Clozapine combined with Venlafaxine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Life Threatening 9/25/2009 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 40 Female 10/19/2009 Physician United States
Primary
Concomitant
Syncope Other Serious 33 Female 10/20/2009 Physician United Kingdom
Primary
Secondary
Sinus Tachycardia Other Serious 27 Male 3/12/2010 Other Health Professional United States
Primary
Concomitant
Laparotomy Life Threatening 52 Female 3/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Stent Placement Life Threatening 3/3/2010 38 Male 4/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Other Serious 33 Female 5/17/2010 Physician United Kingdom
Primary
Secondary
Syncope Other Serious 33 Female 6/3/2010 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 8/19/2009 74 Female 186 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 5/7/2009 33 Female 7/12/2010 Physician United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 6/16/2010 31 Female 8/3/2010 Physician Argentina
Primary
Concomitant
Syncope Other Serious 5/7/2009 33 Female 9/14/2010 Physician United Kingdom
Primary
Secondary
Somnolence Other Serious 37 Female 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Death 37 10/6/2010 Other Health Professional
Primary
Secondary
Somnolence Death 37 Female 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 36 Male 10/25/2010 Consumer Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Somnolence Other Serious 36 Male 10/29/2010 Consumer Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Sepsis Hospitalization 36 Male 11/15/2010 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Urinary Tract Infection Other Serious Female 11/18/2010 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious Female 12/7/2010 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Other Serious 5/7/2009 33 Female 172 lb 12/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Death 5/7/2009 33 Female 12/21/2010 Physician France
Primary
Secondary
Vomiting Death 5/7/2009 33 Female 172 lb 12/29/2010 Physician United Kingdom
Primary
Secondary
Toxicity To Various Agents Death 5/7/2009 33 Female 172 lb 1/3/2011 Physician United Kingdom
Primary
Secondary
Anticonvulsant Drug Level Increased Death 5/7/2009 33 Female 172 lb 1/12/2011 Physician United Kingdom
Primary
Secondary
Sinusitis Hospitalization Female 189 lb 1/7/2011 Lawyer United States
Primary
Concomitant
Vomiting Death 5/7/2009 33 Female 172 lb 1/24/2011 Physician United Kingdom
Primary
Secondary
Pneumonia Death 35 Male 2/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 58 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Epilepsy Death 5/7/2009 33 Female 172 lb 2/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Death 35 Male 2/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 35 Male 2/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Death 3/1/2011 Other Health Professional Australia
Primary
Concomitant
Asthma Death 3/3/2011 Other Health Professional Australia
Primary
Concomitant
Death Death 58 Female 3/7/2011 Other Health Professional United States
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 3/18/2011 Other Health Professional Australia
Primary
Concomitant
Pyrexia Death 3/18/2011 Other Health Professional Australia
Primary
Concomitant
Gastrointestinal Hypomotility Death 37 Female 3/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/30/2011 Female 3/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Circulatory Collapse Death 37 Female 4/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tardive Dyskinesia Other Serious 61 Female 5/6/2011 Physician Turkey
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 5/12/2011 Other Health Professional Australia
Primary
Concomitant
Pyrexia Other Serious 5/12/2011 Pharmacist Australia
Primary
Concomitant
Pulmonary Arterial Pressure Other Serious 3/1/2011 38 Male 5/25/2011 Other Health Professional France
Primary
Concomitant
Haemorrhage Other Serious Male 6/4/2011 Consumer United Kingdom
Primary
Concomitant
Constipation Hospitalization 2/22/2011 72 Male 6/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Fall Hospitalization 4/28/2003 55 Male 6/8/2011 United Kingdom
Primary
Concomitant
Fall Hospitalization Male 6/8/2011 Pharmacist United Kingdom
Primary
Concomitant
Pneumonia Death Male 6/8/2011 Consumer United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious Male 6/8/2011 Physician New Zealand
Primary
Concomitant
Emphysema Other Serious 10/16/2006 63 Female 6/4/2011 Consumer United Kingdom
Primary
Concomitant
Pulmonary Embolism Death Female 6/4/2011 Consumer United Kingdom
Primary
Concomitant
Muscular Weakness Disability 3/19/2008 42 Female 6/2/2011 Consumer United Kingdom
Primary
Concomitant
Weight Increased Other Serious 2/1/2008 20 Male 6/3/2011 Physician United Kingdom
Primary
Concomitant
Coronary Artery Disease Death Male 6/1/2011 Physician Canada
Primary
Concomitant
Neutrophil Count Increased Hospitalization 7/5/2007 61 Female 104 lb 6/5/2011 Physician Ireland
Primary
Concomitant
Myocardial Infarction Death Female 154 lb 6/9/2011 United Kingdom
Primary
Concomitant
Pneumonia Hospitalization Female 5/30/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cardiovascular Disorder Other Serious Male 6/10/2011 Physician United Kingdom
Primary
Concomitant
Thrombocytosis Death 5/1/2002 22 Male 6/10/2011 Consumer United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Disability 4/6/2011 58 Female 6/13/2011 Physician United Kingdom
Primary
Concomitant
Convulsion Life Threatening Female 6/13/2011 Pharmacist United Kingdom
Primary
Concomitant
Bronchial Carcinoma Other Serious Male 6/13/2011 Physician United Kingdom
Primary
Concomitant
Abdominal Pain Hospitalization Male 6/13/2011 Pharmacist United Kingdom
Primary
Concomitant
Blood Potassium Decreased Hospitalization Male 6/13/2011 Physician Ireland
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious Female 6/11/2011 Physician United Kingdom
Primary
Concomitant
Depressed Mood Hospitalization Male 6/14/2011 Physician United Kingdom
Primary
Concomitant
Blood Sodium Decreased Other Serious Male 182 lb 6/15/2011 Consumer United Kingdom
Primary
Concomitant
Haematemesis Hospitalization 7/9/2004 57 Female 6/15/2011 Physician United Kingdom
Primary
Concomitant
Mean Cell Volume Increased Other Serious 6/28/2004 51 Female 6/15/2011 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 11/15/2004 47 Male 6/15/2011 Physician Ireland
Primary
Concomitant
Renal Failure Hospitalization Male 6/16/2011 Physician United Kingdom
Primary
Concomitant
Cyanosis Other Serious Female 6/17/2011 Physician United Kingdom
Primary
Concomitant
Neutropenia Other Serious 3/4/2011 31 Male 6/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 1/1/2008 45 Male 6/17/2011 Other Health Professional Ireland
Primary
Concomitant
Aortic Valve Incompetence Other Serious 1/1/2005 54 Male 6/17/2011 Physician Germany
Primary
Concomitant
Congestive Cardiomyopathy Other Serious 1/1/2011 41 Male 6/20/2011 Physician United Kingdom
Primary
Concomitant
Ejection Fraction Decreased Hospitalization 1/1/2011 33 Male 6/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Myoclonus Other Serious 5/3/2011 64 Female 6/22/2011 Physician United Kingdom
Primary
Concomitant
Leukopenia Other Serious 7/1/2010 55 Male 330 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Malnutrition Death 12/23/2010 77 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Other Serious 12/29/2010 82 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 4/18/2011 21 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/6/2010 52 Female 6/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Diverticulitis Death 4/8/2011 61 Male 6/27/2011 Physician United Kingdom
Primary
Concomitant
Overdose Hospitalization Male 6/27/2011 Physician Ireland
Primary
Secondary
Concomitant
Neutropenia Other Serious 10/6/2010 52 Female 6/28/2011 Physician United Kingdom
Primary
Concomitant
Accidental Poisoning Death 46 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Accidental Poisoning Death 46 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Diabetes Mellitus Life Threatening Female 6/29/2011 Pharmacist United Kingdom
Primary
Concomitant
Personality Disorder Other Serious Female 6/30/2011 Physician United Kingdom
Primary
Concomitant
Mental Impairment Hospitalization 1/1/2011 41 Male 7/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Myoclonus Other Serious 5/3/2011 64 Female 7/6/2011 Physician United Kingdom
Primary
Concomitant
Toxicity To Various Agents Death 46 6/30/2011 Physician United Kingdom
Primary
Concomitant
Diarrhoea Death 4/8/2011 61 Male 7/11/2011 Pharmacist United Kingdom
Primary
Concomitant
Pneumonia Death 46 7/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Accidental Poisoning Death 46 7/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Oedema Death 46 7/12/2011 Other Health Professional Australia
Primary
Secondary
Overdose Death 46 7/12/2011 Other Health Professional Australia
Primary
Secondary
Antipsychotic Drug Level Below Therapeutic Hospitalization 6/16/2011 37 Male 7/13/2011 Physician Australia
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 4/26/2011 38 Female 7/20/2011 Physician United Kingdom
Primary
Concomitant
Social Avoidant Behaviour Hospitalization 9/1/2010 38 Female 7/25/2011 Physician Ireland
Primary
Secondary
Concomitant
Emotional Distress Other Serious 4/24/2011 44 Male 197 lb 7/25/2011 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 9/1/2010 38 Female 7/25/2011 Physician Ireland
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 46 7/26/2011 Physician Australia
Primary
Secondary
Malaise Other Serious Male 7/29/2011 Other Health Professional United Kingdom
Primary
Concomitant
Intentional Overdose Hospitalization 6/25/2011 37 Female 7/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Lower Respiratory Tract Infection Other Serious 7/26/2010 43 Male 8/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Self Esteem Decreased Life Threatening 7/1/2010 37 Male 8/9/2011 Physician Ireland
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Hospitalization 6/25/2011 37 Female 8/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 4/24/2011 44 Male 197 lb 8/11/2011 Physician United Kingdom
Primary
Concomitant
Antipsychotic Drug Level Above Therapeutic Other Serious 5/3/2011 64 Female 8/17/2011 Physician United Kingdom
Primary
Concomitant
Self Esteem Decreased Life Threatening 7/22/2010 37 Male 8/23/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 7/1/2010 37 Male 8/23/2011 Physician Ireland
Primary
Secondary
Concomitant
Self Esteem Decreased Hospitalization 7/22/2010 37 Male 8/23/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 1/1/1994 45 Female 8/24/2011 Physician Ireland
Primary
Concomitant
Clostridium Test Positive Hospitalization 10/3/2005 35 Male 10/5/2011 Consumer Canada
Primary
Secondary
Concomitant
Jaundice Other Serious 48 Male 10/5/2011 Consumer United Kingdom
Primary
Concomitant
Pain Hospitalization Female 11/11/2011 Consumer United States
Primary
Concomitant
Pain Hospitalization 2/1/2011 47 Female 11/14/2011 Consumer Switzerland
Primary
Concomitant
Death Death 58 Female 12/19/2011 Other Health Professional United States
Primary
Secondary
Death Death 58 Female 12/20/2011 Other Health Professional United States
Primary
Secondary
Death Death 43 Female 12/30/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2010 43 Female 1/11/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 1/1/2010 43 Female 1/9/2012 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 43 Female 2/2/2012 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Life Threatening 43 Female 2/16/2012 Physician United States
Primary
Concomitant
Cardiac Arrest Death 43 Female 4/2/2012 Other Health Professional United States
Primary
Secondary
Drug Interaction Other Serious 3/5/2012 33 Male 4/2/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Neutropenia Other Serious 3/5/2012 33 Male 4/5/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Hypertension Other Serious 3/5/2012 33 Male 4/4/2012 Physician
Primary
Secondary
Concomitant
Hypertension Other Serious 3/5/2012 33 Male 4/10/2012 Physician Denmark
Primary
Secondary
Concomitant
Completed Suicide Death 43 Female 4/27/2012 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/23/2012 33 Male 5/11/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Antipsychotic Drug Level Above Therapeutic Other Serious 42 Male 5/16/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Antipsychotic Drug Level Above Therapeutic Other Serious 42 Male 5/16/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Interaction Other Serious 3/5/2012 33 Male 5/15/2012 Physician Denmark
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 42 Male 5/21/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Neutrophil Count Decreased Other Serious 3/23/2012 33 Male 5/22/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Neutropenia Other Serious 3/23/2012 33 Male 5/22/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 33 Male 5/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hiv Test Positive Other Serious 3/23/2012 33 Male 5/18/2012 Other Health Professional
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/23/2012 33 Male 5/23/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Neutropenia Other Serious 3/5/2012 33 Male 5/23/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Psychotic Disorder Other Serious 42 Male 5/24/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Neutropenia Other Serious 3/5/2012 33 Male 5/25/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Neutropenia Other Serious 3/23/2012 33 Male 6/1/2012 Physician United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 3/23/2012 33 Male 6/8/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
White Blood Cell Count Decreased Death 3/23/2012 33 Male 6/12/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Multi-organ Failure Death 6/17/2011 72 Male 6/28/2012 Pharmacist United States
Primary
Concomitant

Drug Data