Clozapine combined with Sertraline Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 12/19/2005 65 Female 12/29/2005 United States
Primary
Concomitant
Staphylococcal Infection Death 11/28/2005 44 Male 1/10/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Death 11/28/2005 44 Male 352 lb 2/9/2006 Physician United States
Primary
Concomitant
Intestinal Obstruction Required Intervention 8/20/2005 52 Male 213 lb 12/14/2005 Physician United States
Primary
Concomitant
Antipsychotic Drug Level Increased Death 43 Male 7/5/2007 United Kingdom
Primary
Concomitant
Weight Decreased Life Threatening 5/2/2006 24 Female 5/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious Female 7/1/2008 Pharmacist Australia
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 19 Male 8/7/2008 Consumer Australia
Primary
Secondary
Thrombocytopenia Other Serious 19 Male 8/7/2008 Australia
Primary
Secondary
Temporomandibular Joint Syndrome Other Serious 56 Female 8/14/2009 Canada
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 24 Female 12/25/2009 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 24 Female 1/8/2010 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/2/2006 23 Female 1/11/2010 Physician United Kingdom
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 6/16/2010 31 Female 8/3/2010 Physician Argentina
Primary
Concomitant
Sinus Tachycardia Other Serious 7/2/2010 27 Male 8/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious 5/25/2008 28 Male 8/24/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Hypomotility Other Serious 41 Male 9/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Oedema Other Serious 41 Male 9/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Gastrointestinal Hypomotility Death 41 Male 9/17/2010 Physician United Kingdom
Primary
Secondary
Gastrointestinal Hypomotility Other Serious 41 Male 9/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Gastrointestinal Hypomotility Death 41 Male 9/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Gastrointestinal Hypomotility Other Serious 9/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Gastrointestinal Hypomotility Other Serious 41 Male 9/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Gastrointestinal Hypomotility Other Serious 41 Male 9/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Gastrointestinal Hypomotility Other Serious 41 Male 9/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Gastrointestinal Hypomotility Other Serious 41 Male 9/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Oedema Life Threatening 41 Male 9/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Spleen Congestion Death 41 9/22/2010 Other Health Professional
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Hypoxic-ischaemic Encephalopathy Other Serious 9/15/2010 55 Female 10/21/2010 Physician United States
Primary
Concomitant
Pulmonary Oedema Other Serious 10/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Death 41 Male 10/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Multiple Sclerosis Hospitalization 12/1/2009 12/14/2010 Physician United States
Primary
Concomitant
Arteriosclerosis Other Serious 3/18/2011 Other Health Professional Australia
Primary
Concomitant
Drug Administered At Inappropriate Site Other Serious 2/23/2011 42 Female 130 lb 3/21/2011 Physician United States
Primary
Secondary
Concomitant
Drug Administered At Inappropriate Site Other Serious 2/23/2011 42 Female 130 lb 3/21/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 41 Male 5/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Extrasystoles Other Serious Male 5/27/2011 Physician Canada
Primary
Secondary
Concomitant
Megacolon Death 6/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Dyspnoea Other Serious 1/1/2011 46 Male 6/6/2011 Physician United Kingdom
Primary
Concomitant
Dyspnoea Life Threatening 2/29/2004 34 Male 6/6/2011 Physician Canada
Primary
Concomitant
Gastrointestinal Hypomotility Other Serious 41 Male 6/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Toxicity To Various Agents Other Serious 6/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Pneumonia Hospitalization 11/3/2005 68 Female 6/8/2011 Other Health Professional Canada
Primary
Concomitant
Panic Attack Other Serious Female 6/4/2011 Physician Australia
Primary
Secondary
Tibia Fracture Hospitalization 11/1/2005 57 Female 6/7/2011 Physician Canada
Primary
Concomitant
Breast Cancer Other Serious Female 6/3/2011 Physician Canada
Primary
Concomitant
Electrocardiogram Abnormal Other Serious 5/10/2006 40 Female 6/5/2011 Physician Australia
Primary
Concomitant
Asthma Hospitalization 10/5/2008 47 Female 225 lb 6/5/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Death Female 295 lb 6/8/2011 Australia
Primary
Concomitant
Visual Impairment Other Serious 1/1/1998 31 Male 6/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 7/1/2007 57 Male 6/5/2011 Ireland
Primary
Concomitant
Abscess Hospitalization 6/27/2007 49 Female 6/5/2011 Physician United Kingdom
Primary
Concomitant
Hemiplegia Hospitalization 11/24/2001 48 Female 6/10/2011 Physician Canada
Primary
Concomitant
Hepatic Steatosis Other Serious 9/27/2000 31 Male 6/10/2011 Consumer United Kingdom
Primary
Concomitant
Tachycardia Other Serious 10/5/2008 47 Female 225 lb 6/12/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Hospitalization 12/20/2002 64 Male 6/13/2011 Consumer Canada
Primary
Concomitant
Urinary Tract Infection Other Serious Female 6/11/2011 United Kingdom
Primary
Concomitant
Cholelithiasis Hospitalization Female 6/12/2011 Physician United Kingdom
Primary
Concomitant
Neoplasm Malignant Other Serious Male 6/14/2011 Other Health Professional Canada
Primary
Concomitant
Salivary Hypersecretion Other Serious Female 6/15/2011 Physician United Kingdom
Primary
Concomitant
Pre-eclampsia Hospitalization Female 6/16/2011 Physician Australia
Primary
Concomitant
Cor Pulmonale Death 10/9/2010 40 Male 6/17/2011 Consumer United Kingdom
Primary
Concomitant
Medication Error Other Serious Female 6/20/2011 Physician United Kingdom
Primary
Concomitant
Asthma Hospitalization 10/5/2008 47 Female 225 lb 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/5/2008 47 Female 225 lb 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 41 Male 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Oedema Other Serious 41 Male 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Oedema Death 41 Male 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Congestion Death 41 Male 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Monocyte Count Increased Hospitalization 10/5/2008 47 Female 225 lb 6/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/17/2010 44 Male 6/22/2011 Physician United States
Primary
Concomitant
Granulocytopenia Other Serious 5/24/2010 22 Female 185 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 6/2/2010 60 Male 181 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Death 82 Female 210 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 7/21/2010 46 Male 193 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Agranulocytosis Other Serious 8/9/2010 33 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Neutrophil Count Increased 5/25/2010 77 Female 6/22/2011 Other Health Professional United States
Primary
Concomitant
Granulocytopenia Other Serious 10/4/2010 51 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 10/15/2010 43 Male 180 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Road Traffic Accident Death 11/4/2010 31 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Pneumonia Other Serious 12/28/2010 71 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 11/22/2010 63 Male 228 lb 6/22/2011 Other Health Professional United States
Primary
Concomitant
Granulocytopenia Other Serious 11/24/2010 71 Female 164 lb 6/22/2011 Physician United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 10/8/2010 69 Male 6/28/2011 Other Health Professional Ireland
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 6/3/2011 15 Female 6/28/2011 Physician United Kingdom
Primary
Secondary
Loss Of Consciousness Other Serious 1/1/1998 41 Male 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Body Temperature Increased Other Serious 10/5/2008 47 Female 6/21/2011 Physician Denmark
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/1998 41 Male 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 1/1/1998 41 Male 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/1998 41 Male 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fall Other Serious 1/1/1998 41 Male 7/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 5/21/2011 44 Male 164 lb 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/3/2011 15 Female 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Death Death Male 7/6/2011 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 6/3/2011 15 Female 7/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Neutropenia Hospitalization 6/3/2011 15 Female 6/24/2011 United Kingdom
Primary
Secondary
Neutropenia Hospitalization 6/3/2011 15 Female 7/7/2011 Physician
Primary
Secondary
Mean Cell Volume Decreased Other Serious 5/11/2010 53 Female 7/19/2011 Other Health Professional Canada
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 6/10/2011 15 Female 7/8/2011 Other Health Professional Denmark
Primary
Secondary
Death Death Male 7/22/2011 Physician United Kingdom
Primary
Concomitant
Overweight Other Serious 1/10/2011 51 Male 7/25/2011 Physician United Kingdom
Primary
Concomitant
Neutropenia Other Serious Female 7/25/2011 Pharmacist Canada
Primary
Concomitant
Cardiac Arrest Death 7/3/2011 65 Female 7/28/2011 Other Health Professional Canada
Primary
Concomitant
Neutropenia Other Serious 5/21/2011 44 Male 164 lb 7/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/21/2011 44 Male 164 lb 8/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Local Swelling Other Serious 5/1/2011 45 Female 8/1/2011 Physician Ireland
Primary
Concomitant
Death Death 7/13/2011 64 Male 8/1/2011 Physician United Kingdom
Primary
Concomitant
Urosepsis Other Serious Female 8/3/2011 Physician Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/21/2011 44 Male 164 lb 8/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Seasonal Allergy Other Serious 5/21/2011 44 Male 164 lb 8/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/1/2011 45 Female 8/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rash Erythematous Other Serious Female 8/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 4/27/2011 67 Male 8/22/2011 Physician United Kingdom
Primary
Concomitant
Overdose Other Serious Female 8/30/2011 Other Health Professional United Kingdom
Primary
Concomitant
Monocyte Count Increased Hospitalization 10/5/2008 47 Female 225 lb 9/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased 11/5/2003 41 Male 8/26/2011 Physician Canada
Primary
Concomitant
Diarrhoea Other Serious 7/13/2011 44 Female 9/6/2011 Other Health Professional Ireland
Primary
Concomitant
Metastases To Central Nervous System Hospitalization 6/18/2011 58 Female 9/7/2011 Physician Ireland
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/1/2011 45 Female 9/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Blood Urea Increased Other Serious 3/16/2010 73 Female 9/23/2011 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 5/1/2011 45 Female 9/23/2011 Pharmacist United Kingdom
Primary
Concomitant
Respiratory Failure Life Threatening 1/1/2011 46 Male 9/29/2011 Pharmacist United Kingdom
Primary
Concomitant
Injury Hospitalization 8/1/2011 48 Male 10/7/2011 Physician United Kingdom
Primary
Concomitant
Haemoglobin Decreased Disability 5/1/2011 45 Female 10/7/2011 Other Health Professional Ireland
Primary
Concomitant
Sinus Tachycardia Other Serious 5/1/2011 17 Female 173 lb 10/10/2011 Physician United Kingdom
Primary
Concomitant
Clostridium Test Positive Hospitalization 10/3/2005 35 Male 10/5/2011 Consumer Canada
Primary
Secondary
Concomitant
Pneumonia Life Threatening 8/30/2001 48 Male 11/7/2011 Physician Canada
Primary
Concomitant
Disorientation Other Serious 85 Female 115 lb 11/22/2011 Brazil
Primary
Secondary
Concomitant
Pneumonia Other Serious Female 11/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Partial Seizures With Secondary Generalisation Other Serious 19 Male 12/5/2011 Other Health Professional India
Primary
Secondary
Myoclonic Epilepsy Other Serious 8/1/2011 25 Male 154 lb 12/15/2011 Physician Denmark
Primary
Concomitant
White Blood Cell Count Increased Disability 11/15/2010 41 Male 12/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Completed Suicide Death 1/1/2010 56 Male 1/10/2012 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2010 56 Male 1/11/2012 Physician United States
Primary
Secondary
Overdose Death 56 Male 1/23/2012 Physician United States
Primary
Secondary
Completed Suicide Death 56 Male 1/18/2012 Other Health Professional United States
Primary
Secondary
Uterine Leiomyoma Hospitalization 9/1/2011 Female 1/31/2012 Physician Croatia (Local Name: Hrvatska)
Primary
Secondary
Deep Vein Thrombosis Death Female 2/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Cardiomegaly Death 34 Male 2/8/2012 Other Health Professional United Kingdom
Primary
Concomitant
Cardiopulmonary Failure Other Serious 34 Male 2/8/2012 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 1/1/2011 24 Male 2/21/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram Qt Shortened Other Serious 1/12/2012 22 Male 2/22/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bradycardia Other Serious Male 3/1/2012 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 34 Male 4/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Completed Suicide Death 56 Male 4/3/2012 Other Health Professional United States
Primary
Secondary
Embolism Other Serious 1/1/2011 57 Male 187 lb 4/13/2012 Physician Switzerland
Primary
Concomitant
Arteriosclerosis Coronary Artery Death 34 Male 4/10/2012 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 4/1/2012 20 Female 4/23/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 4/1/2012 20 Female 4/25/2012 Physician United Kingdom
Primary
Concomitant
Interacting

Drug Data