Clozapine combined with Risperidone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Hospitalization 11/17/2005 44 Male 2/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thinking Abnormal Other Serious 1/1/2002 60 Female 2/6/2006 Physician Switzerland
Primary
Concomitant
Death Death 1/10/2006 62 Male 2/27/2006 United States
Primary
Concomitant
Neuroborreliosis Other Serious 5/1/2005 41 Male 3/10/2006 Physician Germany
Primary
Concomitant
Small Intestinal Obstruction Death 1/7/2006 38 Female 3/7/2006 United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 8/9/2005 54 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 5/9/2002 34 Female 218 lb 12/20/2004 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Death 8/7/2005 54 Female 170 lb 12/14/2005 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Death 1/7/2006 38 Female 148 lb 3/28/2006 United States
Primary
Concomitant
Respiratory Failure Death 4/22/2006 30 Female 5/11/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 7/25/2005 17 Female 180 lb 1/10/2006 United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Death 6/1/2006 45 Male 6/16/2006 United States
Primary
Concomitant
Death Death 5/14/2006 57 Female 6/21/2006 United States
Primary
Concomitant
Myocardial Infarction Death 6/1/2006 45 Male 7/6/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/3/2006 52 Female 3/13/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/7/2005 40 Female 220 lb 5/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/3/2006 60 Male 3/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/25/2006 23 Female 167 lb 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/23/2006 23 Male 180 lb 5/17/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 2/7/2006 45 Male 6/1/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/12/2005 47 Female 2/28/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/1/2005 44 Male 163 lb 6/30/2006 United States
Primary
Secondary
Concomitant
Leukopenia Life Threatening 10/17/2005 59 Female 2/3/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 10/17/2005 46 Male 1/27/2006 Consumer United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 9/26/2005 36 Male 259 lb 1/17/2006 United States
Primary
Concomitant
Leukopenia Life Threatening 10/5/2005 72 Male 263 lb 4/26/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 9/19/2005 44 Female 1/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/7/2005 28 Female 5/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/23/2005 44 Male 4/25/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/20/2005 32 Male 2/3/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/27/2005 70 Female 228 lb 3/9/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/3/2005 47 Male 2/14/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/28/2005 37 Male 2/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/24/2005 79 Female 2/13/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/20/2005 37 Male 220 lb 1/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/19/2005 31 Male 1/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/18/2005 39 Female 2/13/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/12/2005 49 Male 225 lb 3/1/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/7/2005 46 Male 141 lb 2/14/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/10/2005 48 Male 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/31/2005 47 Female 92 lb 2/13/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 10/31/2005 48 Female 3/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/8/2005 59 Female 3/22/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 1/20/2005 53 Female 6/21/2006 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 4/13/2006 29 Male 218 lb 5/23/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/3/2006 26 Female 5/30/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 4/5/2006 43 Female 140 lb 6/12/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 9/13/2005 48 Male 1/13/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 10/10/2005 32 Male 3/15/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/29/2005 53 Female 1/5/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/8/2005 33 Male 153 lb 3/14/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/12/2005 49 Male 220 lb 1/16/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 31 Male 7/21/2006 Physician India
Primary
Concomitant
Small Cell Carcinoma Death 7/26/2006 45 Female 8/9/2006 United States
Primary
Concomitant
Overdose Life Threatening 5/5/2006 37 Female 8/17/2006 United Kingdom
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 2/22/2006 46 Female 5/8/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/31/2005 27 Male 4/25/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/3/2006 46 Male 5/9/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 3/1/2006 60 Female 5/18/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/20/2006 29 Male 6/12/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 2/10/2006 54 Female 6/1/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/17/2005 26 Male 1/9/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/15/2005 54 Male 198 lb 1/9/2006 United States
Primary
Concomitant
Death Death 8/1/2006 51 Male 8/24/2006 United States
Primary
Concomitant
Small Cell Carcinoma Death 7/26/2006 45 Female 8/31/2006 United States
Primary
Concomitant
Trismus Other Serious 47 Female 9/4/2006 United States
Primary
Concomitant
Treatment Noncompliance Death 7/27/2006 38 Female 10/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 64 Female 11/7/2006 Other Health Professional Netherlands
Primary
Secondary
Death Death 10/8/2006 59 Male 10/27/2006 United States
Primary
Concomitant
Sepsis Hospitalization 7/12/2006 37 Female 11/2/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 4/30/2005 38 Male 12/2/2006 Physician Canada
Primary
Concomitant
Sudden Death Death 7/7/2006 35 Male 269 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 10/1/1999 47 Female 238 lb 1/8/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Death 45 Male 1/23/2007 India
Primary
Concomitant
Weight Increased Other Serious 3/1/2003 42 Male 301 lb 1/25/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 33 Female 168 lb 3/14/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 60 Female 5/1/2007 Germany
Primary
Secondary
Leukocytosis 5/23/2007 60 Male 169 lb 5/31/2007 Pharmacist United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2000 28 Male 253 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 43 Male 250 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2001 37 Male 154 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Cardiac Tamponade Death 6/1/2007 Female 225 lb 6/15/2007 Physician United States
Primary
Concomitant
Wound Evisceration Hospitalization 11/20/2006 Male 8/10/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/6/2007 47 Male 154 lb 8/7/2007 Pharmacist United States
Primary
Concomitant
Dysphagia Other Serious 9/1/2006 46 Female 132 lb 9/7/2007 Other Health Professional United States
Primary
Secondary
Suicide Attempt Life Threatening 11/18/2006 Male 9/21/2007 Other Health Professional France
Primary
Concomitant
Tardive Dyskinesia Other Serious 28 Male 9/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 25 Female 10/3/2007 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2007 Male 180 lb 10/11/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 25 Female 10/5/2007 Netherlands
Primary
Secondary
Concomitant
Weight Increased Other Serious 25 Female 10/24/2007 Netherlands
Primary
Secondary
Concomitant
Dry Eye Other Serious 8/1/2003 17 Male 11/2/2007 Physician Switzerland
Primary
Concomitant
Weight Increased Other Serious 25 Female 11/6/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 62 Male 11/13/2007 Physician Hungary
Primary
Concomitant
Weight Increased Hospitalization 25 Female 11/20/2007
Primary
Secondary
Concomitant
Dysphagia Hospitalization 9/1/2006 46 Female 11/22/2007 United States
Primary
Secondary
Concomitant
Dry Eye Other Serious 8/1/2003 17 Male 11/30/2007 Physician Switzerland
Primary
Concomitant
Visual Disturbance Hospitalization 1/1/2005 44 Male 270 lb 10/9/2007 Lawyer United States
Primary
Concomitant
Pyrexia 8/18/2007 36 Male 195 lb 8/18/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 25 Female 12/18/2007 Netherlands
Primary
Secondary
Concomitant
Dry Eye Other Serious 8/1/2003 17 Male 12/29/2007 Physician Switzerland
Primary
Concomitant
Somnolence Hospitalization 1/16/2008 Other Health Professional China
Primary
Secondary
Suicidal Ideation Hospitalization 7/1/2005 Female 156 lb 1/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization Male 12/7/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 9/18/2007 51 Male 12/7/2007 United States
Primary
Concomitant
Intentional Self-injury Other Serious 33 Female 2/29/2008 United States
Primary
Secondary
Concomitant
Torticollis Other Serious 59 Male 3/14/2008 Other Health Professional United States
Primary
Secondary
Weight Increased Hospitalization 1/1/2000 15 Male 4/7/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 17 Female 116 lb 4/10/2008 Other Health Professional Mexico
Primary
Secondary
Neutropenia Other Serious 46 Female 4/11/2008 Brazil
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 40 Female 6/1/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Ultrasound Scan Abnormal Other Serious 5/1/2008 Male 6/10/2008 Physician Germany
Primary
Concomitant
Neutropenia 55 Male 8/19/2008 United States
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 55 Male 8/25/2008 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 1/13/2008 Male 360 lb 10/8/2008 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Death 8/9/2008 Male 309 lb 10/27/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Tremor Other Serious 35 Male 11/24/2008 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Testis Cancer Other Serious 1/1/2000 Male 187 lb 12/2/2008 Consumer Argentina
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 11/1/2008 59 Female 159 lb 12/5/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Testis Cancer Other Serious 1/1/2000 Male 187 lb 12/8/2008 Consumer Argentina
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 45 Male 12/8/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Neutropenia Other Serious 45 Male 12/8/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Sedation Hospitalization 1/1/2005 32 Male 12/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 1/1/2005 32 Male 12/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Torticollis Hospitalization 35 Male 12/23/2008 Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2000 Male 187 lb 1/6/2009 Consumer Argentina
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 1/1/2008 42 Female 176 lb 1/15/2009 Consumer Denmark
Primary
Secondary
Concomitant
Tremor Other Serious 41 Male 1/21/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Other Serious 28 Male 1/27/2009 Other Health Professional United States
Primary
Secondary
Troponin Increased Other Serious 28 Male 2 lb 1/23/2009 Physician United States
Primary
Secondary
Rhabdomyolysis Other Serious 28 Male 2/6/2009 France
Primary
Secondary
Ventricular Extrasystoles Other Serious 37 Male 2/17/2009 Other Health Professional Germany
Primary
Concomitant
Mania Other Serious 22 Male 2/27/2009 Consumer United States
Primary
Secondary
Tongue Disorder Hospitalization 9/18/2008 Male 182 lb 2/12/2009 Physician United States
Primary
Concomitant
Somnolence 3/12/2009 Other Health Professional United States
Primary
Interacting
Neutropenia Other Serious 45 Male 3/16/2009 Other Health Professional Canada
Primary
Secondary
Pulmonary Oedema Hospitalization 28 Male 3/23/2009 United States
Primary
Concomitant
Suspiciousness Other Serious 37 Male 3/26/2009 Physician Taiwan, Province Of China
Primary
Secondary
Tachypnoea Other Serious 28 Male 3/26/2009 France
Primary
Secondary
Sudden Death Life Threatening Male 3/27/2009 Physician United States
Primary
Secondary
Pulmonary Oedema Other Serious 28 Male 3/27/2009 United Kingdom
Primary
Secondary
Vomiting Other Serious 45 Female 5/14/2009 Other Health Professional Brazil
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious Male 6/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Heat Stroke Hospitalization 4/27/2009 Male 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Influenza Other Serious 4/10/2009 51 Female 6/18/2009 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious Male 6/18/2009 United Kingdom
Primary
Secondary
Concomitant
Hallucination, Auditory Hospitalization 27 Male 6/23/2009 Physician Korea, Republic Of
Primary
Secondary
Influenza Other Serious 4/10/2009 51 Female 7/3/2009 Pharmacist United States
Primary
Concomitant
Somnolence Death Female 8/4/2009 Physician Canada
Primary
Concomitant
Urinary Incontinence Other Serious Male 8/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data