Clozapine combined with Ramipril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neuroborreliosis Other Serious 5/1/2005 41 Male 3/10/2006 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 2/22/2006 46 Male 5/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 9/10/2005 Male 6/5/2006 Consumer Germany
Primary
Concomitant
Silent Myocardial Infarction Death 6/7/2006 82 Female 6/28/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/3/2006 46 Male 5/9/2006 United States
Primary
Concomitant
Renal Failure Acute Life Threatening 2/22/2006 46 Male 9/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/22/2006 46 Male 9/21/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/22/2006 46 Male 10/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 2/22/2006 46 Male 10/12/2006 United Kingdom
Primary
Secondary
Concomitant
Hepatitis Life Threatening 12/13/2004 Female 1/16/2007 Canada
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/22/2006 46 Male 10/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/22/2006 46 Male 10/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/22/2006 46 Male 10/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/22/2006 46 Male 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 9/20/2007 72 Female 2/13/2008 Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/20/2009 30 Male 322 lb 7/15/2009 Physician Ireland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/20/2009 30 Male 322 lb 7/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 7/31/2009 52 Male 10/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 10/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 10/14/2009 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Other Serious 7/31/2009 52 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Salivary Hypersecretion Hospitalization 7/31/2009 52 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Life Threatening 7/31/2009 52 Male 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 7/31/2009 52 Male 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 11/13/2009 United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 7/31/2009 52 Male 11/19/2009
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 12/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 1/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 2/1/2010 56 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 3/25/2010 26 Female 7/14/2010 Physician
Primary
Secondary
Concomitant
Breast Cancer Other Serious 8/1/2010 49 Female 9/21/2010 Other Health Professional Netherlands
Primary
Secondary
Breast Cancer Female Other Serious 49 Female 9/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2010 49 Female 10/14/2010 Other Health Professional Netherlands
Primary
Secondary
Platelet Count Decreased Other Serious 49 Female 10/11/2010 United Kingdom
Primary
Secondary
Concomitant
Off Label Use Death Male 10/20/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 49 Female 10/23/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/1/2010 49 Female 10/28/2010 Physician
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 49 Female 11/6/2010 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Female 11/18/2010 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious Female 12/7/2010 Pharmacist United Kingdom
Primary
Concomitant
General Physical Health Deterioration Other Serious 49 Female 1/17/2011 United Kingdom
Primary
Secondary
Concomitant
Myoclonus Other Serious 6/1/2008 29 Male 6/3/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Metastases To Spine Other Serious 8/1/2010 49 Female 5/31/2011 Physician
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious Male 6/8/2011 Physician United Kingdom
Primary
Concomitant
Bladder Obstruction Hospitalization 2/1/2008 60 Male 6/4/2011 Physician United Kingdom
Primary
Concomitant
Coronary Artery Disease Death Male 6/1/2011 Physician Canada
Primary
Concomitant
Antipsychotic Drug Level Increased Death 1/1/2007 54 Female 6/5/2011 Physician United Kingdom
Primary
Concomitant
Decreased Appetite Other Serious Female 6/4/2011 Physician United Kingdom
Primary
Concomitant
Skin Exfoliation Other Serious 9/6/2006 53 Female 6/4/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/24/2003 53 Male 6/13/2011 Consumer United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 3/22/2006 54 Male 6/14/2011 Consumer United Kingdom
Primary
Concomitant
General Physical Health Deterioration Other Serious 8/1/2010 49 Female 6/7/2011 Physician
Primary
Secondary
Concomitant
Mental Impairment Other Serious 54 Male 6/16/2011 Physician United Kingdom
Primary
Secondary
Blood Glucose Increased Disability 3/3/2006 52 Male 6/16/2011 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 6/1/2008 29 Male 6/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Mental Impairment Other Serious 54 Male 6/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mental Impairment Other Serious 54 Male 6/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebral Disorder Other Serious Female 7/1/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Mitral Valve Disease Other Serious 10/18/2010 57 Male 7/5/2011 Other Health Professional Australia
Primary
Concomitant
Death Death Male 7/6/2011 Physician United Kingdom
Primary
Concomitant
Breast Abscess Other Serious 8/1/2010 49 Female 7/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/1/2010 49 Female 7/8/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 7/1/1995 46 Female 7/14/2011 Physician Ireland
Primary
Concomitant
Mania Hospitalization 6/22/2011 39 Male 7/15/2011 Pharmacist Australia
Primary
Concomitant
Electrocardiogram St Segment Abnormal Other Serious 10/18/2010 57 Male 7/20/2011 Other Health Professional Australia
Primary
Concomitant
Death Death Male 7/22/2011 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Increased Other Serious 8/1/2010 49 Female 7/25/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/1/2010 49 Female 7/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Body Temperature Increased Other Serious 4/14/2011 47 Male 252 lb 7/29/2011 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/1/2010 49 Female 8/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Death 7/23/2011 57 Male 8/12/2011 Other Health Professional Canada
Primary
Concomitant
Circulatory Collapse Hospitalization 6/28/2011 54 Male 8/16/2011 Physician United Kingdom
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 4/1/2011 71 Female 8/16/2011 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 8/1/2010 49 Female 8/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 4/27/2011 67 Male 8/22/2011 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/1/2010 49 Female 8/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/1/2010 49 Female 8/22/2011 Physician United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 8/1/2010 49 Female 8/17/2011 Physician
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Female 9/6/2011 Other Health Professional Canada
Primary
Concomitant
Overdose 7/3/2001 49 Male 8/29/2011 Physician Canada
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/1/2010 49 Female 9/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Female 9/8/2011 Other Health Professional Canada
Primary
Concomitant
Neutrophil Count Increased Other Serious 8/1/2010 49 Female 9/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 8/1/2010 49 Female 9/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Increased Other Serious 8/1/2010 49 Female 9/19/2011 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/1/2010 49 Female 9/19/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/1994 45 Female 9/12/2011 Physician Ireland
Primary
Concomitant
Metastases To Spine Other Serious 8/1/2010 49 Female 9/23/2011 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/1/2010 49 Female 9/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 7/21/2011 51 Male 10/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Schizophrenia Life Threatening 9/6/2011 47 Male 168 lb 10/11/2011 Physician France
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 8/22/2011 52 Male 10/20/2011 Physician Germany
Primary
Secondary
Concomitant
Interacting
Malignant Neoplasm Of Pleura Other Serious 8/1/2011 66 Male 163 lb 11/21/2011 Physician Germany
Primary
Secondary
Concomitant
Inflammation Other Serious 9/1/2011 Female 11/30/2011 Physician Germany
Primary
Concomitant
Dilatation Atrial Hospitalization 1/1/2006 27 Female 1/17/2012 Other Health Professional France
Primary
Concomitant
Dehydration Death 10/6/2011 79 Female 106 lb 2/17/2012 Physician Romania
Primary
Concomitant
Sedation Death 10/6/2011 79 Female 106 lb 3/1/2012 Physician Romania
Primary
Concomitant
Muscle Atrophy Other Serious 1/11/2012 72 Male 3/14/2012 Physician Canada
Primary
Concomitant
Deafness Hospitalization 1/11/2012 72 Male 3/19/2012 Physician Canada
Primary
Concomitant
Starvation Death 10/6/2011 79 Female 106 lb 3/19/2012 Physician Romania
Primary
Concomitant
Death Death 50 Female 3/21/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Increased Other Serious 5/12/2006 Female 3/28/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 3/5/2012 33 Male 4/2/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Neutropenia Other Serious 3/5/2012 33 Male 4/5/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Hypertension Other Serious 3/5/2012 33 Male 4/4/2012 Physician
Primary
Secondary
Concomitant
Hypertension Other Serious 3/5/2012 33 Male 4/10/2012 Physician Denmark
Primary
Secondary
Concomitant
Hypertension Other Serious 5/12/2006 Female 4/17/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Monocyte Count Increased Other Serious 36 Female 4/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertension Life Threatening 3/12/2012 44 Male 4/20/2012 Consumer Denmark
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/23/2012 33 Male 5/11/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Hypertension Other Serious 5/12/2006 36 Female 5/11/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 3/5/2012 33 Male 5/15/2012 Physician Denmark
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 3/23/2012 33 Male 5/22/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Neutropenia Other Serious 3/23/2012 33 Male 5/22/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 33 Male 5/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hiv Test Positive Other Serious 3/23/2012 33 Male 5/18/2012 Other Health Professional
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/23/2012 33 Male 5/23/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Neutropenia Other Serious 3/5/2012 33 Male 5/23/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Constipation Other Serious 5/12/2006 36 Female 5/24/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Hiatus Hernia Other Serious 5/12/2006 36 Female 5/24/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/5/2012 33 Male 5/25/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Malaise Other Serious 5/12/2006 36 Female 5/29/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 5/12/2006 36 Female 5/29/2012 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Disorder Other Serious 5/12/2006 36 Female 5/30/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/5/2012 33 Male 5/24/2012 Physician
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/23/2012 33 Male 5/24/2012 Other Health Professional
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/23/2012 33 Male 6/1/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Petit Mal Epilepsy Other Serious Male 6/6/2012 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/5/2012 33 Male 5/31/2012 Physician
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/23/2012 33 Male 6/8/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Hyponatraemia Hospitalization 7/31/2009 52 Male 6/1/2012 Other Health Professional
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 3/23/2012 33 Male 6/12/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Disorder Hospitalization 5/12/2006 36 Female 6/12/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/5/2012 33 Male 6/12/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 3/23/2012 33 Male 6/6/2012 Physician
Primary
Secondary
Concomitant
Constipation Other Serious 33 Male 6/6/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malignant Neoplasm Of Pleura Hospitalization 8/1/2011 66 Male 163 lb 6/25/2012 Physician Germany
Primary
Secondary
Concomitant
Meningioma Hospitalization 2/14/2011 73 Male 6/26/2012 Physician Italy
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 5/15/2012 47 Male 220 lb 6/26/2012 Physician France
Primary
Secondary
Concomitant
Monocyte Count Increased Hospitalization 5/12/2006 36 Female 6/27/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Meningioma Hospitalization 2/14/2011 73 Male 6/29/2012 Consumer Italy
Primary
Concomitant
Abnormal Behaviour Other Serious 5/15/2012 47 Male 220 lb 7/4/2012 Other Health Professional France
Primary
Secondary
Concomitant
Physical Assault Other Serious 5/12/2006 36 Female 7/6/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytosis Other Serious 5/12/2006 35 Female 7/12/2012 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Disorder Hospitalization 5/12/2006 36 Female 7/13/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Mean Cell Volume Decreased Other Serious 5/12/2006 35 Female 7/16/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 5/12/2006 36 Female 7/18/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 36 Female 7/20/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 7/12/2006 36 Female 7/13/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant

Drug Data