Clozapine combined with Quetiapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Mental Status Changes Other Serious 9/14/2005 44 Male 135 lb 2/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 27 Male 2/17/2006 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2006 64 Female 2/24/2006 Physician United States
Primary
Concomitant
Death Death 10/1/2005 55 Female 3/3/2006 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Other Serious 9/14/2005 44 Male 135 lb 12/14/2005 Physician United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 9/15/2005 22 Male 2/8/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/15/2006 43 Female 202 lb 4/17/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/13/2006 48 Female 203 lb 5/18/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/13/2006 23 Female 5/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/8/2006 24 Male 5/9/2006 Consumer United States
Primary
Concomitant
Drug Toxicity Hospitalization 36 Male 6/12/2007 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 36 Male 6/21/2007 Physician United States
Primary
Concomitant
Pleurothotonus Other Serious 39 Female 1/7/2008 France
Primary
Secondary
Interacting
Suicidal Ideation Hospitalization 7/1/2005 Female 156 lb 1/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Torticollis Other Serious 59 Male 3/14/2008 Other Health Professional United States
Primary
Secondary
Psychotic Disorder Other Serious 1/1/2004 Female 8/29/2008 Physician
Primary
Concomitant
Completed Suicide Death Female 12/29/2008 Pharmacist United States
Primary
Secondary
Vomiting Other Serious 4/1/2009 Female 5/4/2009 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 8/18/2008 74 Male 5/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 47 Female 9/16/2009 Other Health Professional Spain
Primary
Concomitant
Sudden Death Death 4/27/2003 28 Female 10/12/2009 Physician New Zealand
Primary
Concomitant
Somnolence Other Serious 3/1/2007 42 Male 11/5/2009 Physician India
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/21/2009 55 Female 11/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Increased Other Serious 4/21/2007 25 Male 238 lb 1/4/2010 Australia
Primary
Secondary
Respiratory Disorder Other Serious 69 Female 1/7/2010
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 25 Male 2/1/2010 Other Health Professional United States
Primary
Secondary
Sedation 10/18/2008 54 Male 219 lb 11/18/2008 Other Health Professional United States
Primary
Concomitant
Drug Exposure During Pregnancy Hospitalization 11/1/2009 31 Female 3/11/2010 Physician Australia
Primary
Secondary
Concomitant
Myocarditis Hospitalization 6/15/2007 39 Male 3/25/2010 Physician New Zealand
Primary
Concomitant
Interacting
Weight Increased Other Serious 36 Male 4/6/2010 Other Health Professional Austria
Primary
Secondary
Treatment Failure Other Serious 49 Male 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/21/2009 55 Female 4/22/2010 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 26 Female 5/13/2010 Taiwan, Province Of China
Primary
Secondary
Tremor Other Serious 49 Male 5/17/2010 Other Health Professional United States
Primary
Secondary
Respiratory Failure Other Serious 1/1/2009 26 Female 5/18/2010
Primary
Secondary
Psychotic Disorder Other Serious 26 Female 5/23/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Tardive Dyskinesia Hospitalization 26 Female 5/19/2010 Taiwan, Province Of China
Primary
Secondary
Myasthenia Gravis Hospitalization 26 Female 5/24/2010 Taiwan, Province Of China
Primary
Secondary
Respiratory Failure Other Serious 2/1/2009 26 Female 5/27/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Thought Broadcasting Hospitalization 26 Female 5/25/2010 Taiwan, Province Of China
Primary
Secondary
Tardive Dyskinesia Other Serious 26 Female 6/2/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Leukopenia Other Serious 54 Male 150 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Death 8/13/2009 44 Male 160 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 10/29/2009 62 Female 137 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Hypertension Hospitalization 31 Female 7/1/2010 Other Health Professional Poland
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2010 50 Female 165 lb 7/27/2010 Consumer Canada
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 26 Female 8/10/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Hypertension Hospitalization 31 Female 8/25/2010 Other Health Professional Poland
Primary
Concomitant
Respiratory Failure Hospitalization 26 Female 8/27/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Treatment Noncompliance Hospitalization 10/9/2007 44 Male 8/30/2010 Consumer Poland
Primary
Concomitant
Torticollis Hospitalization 34 Male 8/25/2010 Physician Greece
Primary
Secondary
Concomitant
Hypertension Hospitalization 31 Female 9/9/2010 Other Health Professional Poland
Primary
Concomitant
Traumatic Liver Injury Hospitalization 10/9/2007 44 Male 9/10/2010 Consumer Poland
Primary
Concomitant
Pulmonary Oedema Other Serious 49 Male 174 lb 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Liver Injury Death 49 Male 174 lb 9/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Neuroleptic Malignant Syndrome Hospitalization 49 Male 9/17/2010 Pharmacist United States
Primary
Secondary
Concomitant
Liver Injury Death 49 Male 174 lb 9/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Schizoaffective Disorder Other Serious 30 Male 9/21/2010 Physician United States
Primary
Concomitant
Pulmonary Oedema Death 49 Male 174 lb 9/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 8/9/2010 14 Male 198 lb 9/17/2010 Pharmacist United States
Primary
Secondary
Hypertension Hospitalization 31 Female 9/29/2010 Other Health Professional Poland
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 6/7/2010 44 Male 194 lb 10/12/2010 Physician United States
Primary
Secondary
Concomitant
Salivary Hypersecretion Other Serious 10/1/2010 9 Male 11/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 60 Female 11/11/2010 Germany
Primary
Secondary
Leukopenia Male 11/12/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization Female 11/19/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Syncope Other Serious 10/1/2010 9 Male 11/22/2010 Consumer Canada
Primary
Secondary
Concomitant
Dysarthria Other Serious 10/1/2010 9 Male 1/5/2011 Consumer Argentina
Primary
Secondary
Concomitant
Sinusitis Hospitalization Female 189 lb 1/7/2011 Lawyer United States
Primary
Concomitant
Cardiac Failure Death Female 1/28/2011 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Neutropenia Other Serious 12/29/2010 25 Male 2/2/2011 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/29/2010 25 Male 2/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 30 Male 2/10/2011 Other Health Professional United States
Primary
Secondary
Vision Blurred Hospitalization 11/2/2010 25 Male 2/9/2011 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 9/1/2010 63 Female 2/24/2011 Physician United States
Primary
Secondary
Concomitant
Dyskinesia Other Serious Female 136 lb 2/28/2011 Lawyer United States
Primary
Concomitant
Parkinsonism Other Serious 72 Female 4/15/2011 Physician United States
Primary
Secondary
Acute Hepatic Failure Death 49 Male 174 lb 4/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Intestinal Dilatation Death 49 Male 174 lb 4/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Condition Aggravated Other Serious 54 Male 4/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abnormal Behaviour Hospitalization 21 Male 5/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 21 Male 5/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Incontinence Hospitalization 21 Male 5/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 21 Male 5/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Incontinence Hospitalization 21 Male 5/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Paranoia Hospitalization 21 Male 5/23/2011 Physician United Kingdom
Primary
Secondary
Waxy Flexibility Hospitalization 21 Male 5/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Ineffective Hospitalization 21 Male 5/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Paranoia Hospitalization 21 Male 6/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 26 Female 5/20/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Nocturia Hospitalization 21 Male 5/25/2011 Other Health Professional
Primary
Secondary
Asthma Hospitalization 10/5/2008 47 Female 225 lb 6/5/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 3/10/2008 40 Male 6/8/2011 Physician Canada
Primary
Concomitant
Embolism Hospitalization Male 6/4/2011 Physician United Kingdom
Primary
Concomitant
Death Death 5/23/2007 31 Male 6/1/2011 Other Health Professional Australia
Primary
Secondary
Tachycardia Other Serious 10/5/2008 47 Female 225 lb 6/12/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious Male 6/14/2011 Other Health Professional Canada
Primary
Concomitant
Multiple Drug Overdose Intentional Hospitalization 1/10/2007 42 Female 6/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Abnormal Behaviour Hospitalization 21 Male 6/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Multiple Drug Overdose Intentional Hospitalization 1/10/2007 42 Female 6/16/2011 Consumer Germany
Primary
Secondary
Neutropenia Other Serious 3/4/2011 31 Male 6/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Asthma Hospitalization 10/5/2008 47 Female 225 lb 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/5/2008 47 Female 225 lb 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Monocyte Count Increased Hospitalization 10/5/2008 47 Female 225 lb 6/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukopenia Other Serious 9/13/2010 46 Male 6/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Body Temperature Increased Other Serious 10/5/2008 47 Female 6/21/2011 Physician Denmark
Primary
Concomitant
Infection Hospitalization 4/19/2011 53 Female 7/1/2011 Pharmacist Ireland
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 2/8/2011 39 Female 7/1/2011 Physician New Zealand
Primary
Concomitant
Troponin Increased Hospitalization 2/17/2011 61 Female 176 lb 7/5/2011 Physician Australia
Primary
Concomitant
Psychotic Disorder Other Serious 25 Male 7/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Delusion Other Serious 64 Female 7/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Abnormal Behaviour Other Serious 64 Female 7/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 25 Male 7/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 5/23/2007 31 Male 7/19/2011 Other Health Professional Australia
Primary
Secondary
Respiratory Disorder Other Serious Female 229 lb 7/21/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Dementia With Lewy Bodies Hospitalization 7/22/2011 Consumer United States
Primary
Concomitant
Respiratory Disorder Hospitalization Female 229 lb 7/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Antipsychotic Drug Level Above Therapeutic Other Serious 1/1/2005 53 Male 7/28/2011 New Zealand
Primary
Concomitant
Dyspnoea Hospitalization 32 Female 229 lb 8/1/2011 Physician United Kingdom
Primary
Secondary
Dilatation Ventricular Hospitalization 1/1/2009 20 Female 8/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Petit Mal Epilepsy Other Serious 7/14/2011 9 Male 8/4/2011 Consumer Argentina
Primary
Concomitant
Nocturia Hospitalization 21 Male 8/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 21 Male 8/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Congestive Cardiomyopathy Hospitalization 24 Male 8/10/2011 Other Health Professional Belgium
Primary
Concomitant
Posture Abnormal Hospitalization 21 Male 8/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Heart Rate Increased Hospitalization 1/1/2009 20 Female 8/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Speech Disorder Other Serious 21 Male 8/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Muscular Weakness Other Serious 3/29/2011 49 Female 8/26/2011 Physician United Kingdom
Primary
Concomitant
Subcutaneous Abscess Hospitalization 7/29/2011 31 Male 247 lb 8/30/2011 Physician Australia
Primary
Concomitant
Monocyte Count Increased Hospitalization 10/5/2008 47 Female 225 lb 9/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metastases To Central Nervous System Hospitalization 6/18/2011 58 Female 9/7/2011 Physician Ireland
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 34 Male 191 lb 9/8/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization Female 229 lb 9/9/2011 Physician United Kingdom
Primary
Secondary
Muscular Weakness Hospitalization 3/29/2011 49 Female 9/12/2011 Physician United Kingdom
Primary
Concomitant
Dystonia Other Serious 1/1/2009 34 Male 191 lb 9/13/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 1/1/2009 20 Female 9/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Catatonia Other Serious 1/1/2007 9/16/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Catatonia Other Serious 1/1/2007 37 Male 9/16/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Overdose Hospitalization 3/3/2010 37 Male 9/19/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Schizophrenia Other Serious 32 Female 229 lb 9/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Frontotemporal Dementia Other Serious 7/14/2011 9 Male 9/20/2011 Consumer Argentina
Primary
Concomitant
Mean Cell Haemoglobin Concentration Other Serious 1/1/2009 34 Male 191 lb 9/23/2011 Physician Ireland
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 1/1/2009 20 Female 9/23/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious Female 10/5/2011 Pharmacist United Kingdom
Primary
Concomitant
Pulmonary Oedema Death 9/11/2011 48 Female 10/12/2011 Other Health Professional New Zealand
Primary
Concomitant
Hypertension Hospitalization 49 Male 10/14/2011 Other Health Professional Netherlands
Primary
Concomitant
Hypertension Hospitalization 49 Male 10/14/2011 Other Health Professional Netherlands
Primary
Concomitant
Drug Ineffective Other Serious 49 Male 10/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Lacunar Infarction Other Serious 49 Male 10/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Blood Prolactin Increased Other Serious Female 10/20/2011 Consumer Venezuela
Primary
Concomitant

Drug Data