Clozapine combined with Propranolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Required Intervention 35 Female 174 lb 12/28/2005 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 10/9/2005 51 Male 1/9/2006 France
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/3/2005 36 Male 197 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Convulsion Death 11/6/2005 56 Male 1/24/2006 Other Health Professional United States
Primary
Concomitant
Dementia Alzheimer's Type Death 1/10/2006 83 Female 2/27/2006 United States
Primary
Concomitant
Road Traffic Accident Death 1/25/2006 48 Male 3/6/2006 United States
Primary
Concomitant
Diabetic Ketoacidosis Other Serious 4/22/2005 26 Male 257 lb 6/27/2005 Physician United States
Primary
Concomitant
Drug Level Below Therapeutic Hospitalization 6/1/2005 39 Female 12/14/2005 Other Health Professional United States
Primary
Concomitant
Road Traffic Accident Death 1/25/2006 48 Male 3/23/2006 United States
Primary
Concomitant
Disease Progression Death 1/10/2006 83 Female 4/17/2006 United States
Primary
Concomitant
Post Procedural Complication Death 2/1/2006 53 Male 5/1/2006 United States
Primary
Concomitant
Akathisia Hospitalization 43 Male 5/3/2006 Physician Greece
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/25/2006 34 Male 5/25/2006 United Kingdom
Primary
Concomitant
Rash Macular Other Serious 34 Male 7/21/2006 France
Primary
Concomitant
Granulocytopenia Hospitalization 1/10/2006 25 Male 3/14/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/23/2006 23 Male 180 lb 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/13/2005 36 Male 1/27/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/24/2005 26 Female 1/27/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/16/2005 43 Male 1/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/27/2005 44 Male 1/18/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/28/2005 41 Male 1/20/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/12/2005 51 Female 2/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/17/2005 35 Male 1/30/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/15/2005 22 Male 2/8/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/8/2005 53 Male 1/13/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/19/2005 39 Female 1/16/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/6/2005 17 Male 1/6/2006 Consumer United States
Primary
Concomitant
Syncope Required Intervention 8/6/2006 48 Male 170 lb 10/5/2006 United States
Primary
Concomitant
Cardiac Failure Hospitalization 12/21/2006 46 Female 150 lb 5/1/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2007 17 Male 166 lb 11/12/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nystagmus Hospitalization 40 Female 143 lb 11/26/2007 Physician Israel
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 1/1/2003 31 Male 227 lb 10/9/2007 Lawyer United States
Primary
Concomitant
Immune System Disorder Hospitalization 5/1/2007 17 Male 166 lb 12/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Therapy Regimen Changed 12/2/2005 32 Female 348 lb 12/2/2005 Pharmacist United States
Primary
Concomitant
Tic 10/17/2006 49 Female 189 lb 11/6/2006 Pharmacist United States
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 5/1/2007 17 Male 166 lb 12/19/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2008 59 Male 250 lb 4/18/2008 United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 5/16/2008 33 Female 7/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 6/4/2008 21 Male 8/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 41 Male 1/21/2009 Other Health Professional United States
Primary
Concomitant
Nystagmus Hospitalization 40 Female 143 lb 8/25/2009 Physician Israel
Primary
Concomitant
Diabetic Ketoacidosis Other Serious 5/7/2003 18 Female 180 lb 9/23/2009 United States
Primary
Concomitant
Pneumonia Other Serious 60 Male 5/3/2010 United Kingdom
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 24 Male 6/24/2010 Other Health Professional United States
Primary
Concomitant
Granulocytopenia Other Serious 44 Female 180 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 36 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 27 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 11/27/2009 58 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 34 Female 135 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 3/31/2010 41 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Pneumonia Other Serious 12/29/2009 38 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Fall Other Serious 6/1/2010 58 Male 184 lb 7/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2010 50 Female 165 lb 7/27/2010 Consumer Canada
Primary
Secondary
Concomitant
Fall Other Serious 6/1/2010 58 Male 184 lb 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Fall Other Serious 6/1/2010 58 Male 184 lb 7/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 11/24/2010 25 Female 170 lb 12/10/2010 Pharmacist United States
Primary
Concomitant
Medication Error Death 82 Female 1/21/2011 Physician United States
Primary
Secondary
Medication Error Death 82 Female 1/10/2011 Physician United States
Primary
Secondary
Grand Mal Convulsion Hospitalization 1/31/2011 33 Male 2/14/2011 Pharmacist United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 1/31/2011 33 Male 2/14/2011 Pharmacist United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 1/31/2011 33 Male 2/14/2011 Pharmacist United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 1/31/2011 33 Male 2/14/2011 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 2/10/2011 53 Female 3/1/2011 Consumer Netherlands
Primary
Concomitant
Cognitive Disorder Hospitalization 11/15/2010 77 Male 2/10/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Medication Error Death 82 Female 3/6/2011 Other Health Professional United States
Primary
Secondary
Medication Error Death 82 Female 3/7/2011 Physician United States
Primary
Secondary
Drug Interaction Hospitalization 1/31/2011 33 Male 291 lb 3/25/2011 Pharmacist United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 1/31/2011 33 Male 291 lb 3/25/2011 Pharmacist United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 1/31/2011 33 Male 291 lb 3/25/2011 Pharmacist United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 1/31/2011 33 Male 291 lb 3/25/2011 Pharmacist United States
Primary
Secondary
Concomitant
Bone Marrow Disorder Other Serious Male 4/5/2011 Physician Ireland
Primary
Concomitant
Lip Swelling Other Serious 5/1/2011 52 Female 168 lb 5/31/2011 Consumer United States
Primary
Concomitant
Granulocytopenia Hospitalization 3/8/2011 42 Male 6/3/2011 Pharmacist United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious Male 6/4/2011 Physician Ireland
Primary
Concomitant
Circulatory Collapse Hospitalization 5/17/2004 48 Male 6/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 10/18/2004 54 Female 6/15/2011 Physician United Kingdom
Primary
Concomitant
Lip Swelling Other Serious 5/1/2011 52 Female 168 lb 6/16/2011 Physician United States
Primary
Concomitant
Subarachnoid Haemorrhage Death 5/25/2011 44 Male 209 lb 6/20/2011 Physician United Kingdom
Primary
Concomitant
Colitis Ischaemic Other Serious 2/18/2011 43 Male 6/21/2011 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/1/2005 47 Female 6/22/2011 Other Health Professional Ireland
Primary
Concomitant
Leukopenia Other Serious 5/26/2010 34 Male 176 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 10/5/2010 39 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 58 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Life Threatening 11/15/2010 30 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 1/6/2011 30 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 2/21/2011 27 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Differential White Blood Cell Count Abnormal Hospitalization 1/1/2011 66 Male 7/8/2011 Physician Ireland
Primary
Concomitant
Cryptorchism Other Serious Male 8 lb 7/13/2011 Other Health Professional Germany
Primary
Secondary
C-reactive Protein Increased Other Serious 12/1/2010 40 Male 6/24/2011 Pharmacist France
Primary
Concomitant
Cryptorchism Other Serious Male 8 lb 7/14/2011 Physician Germany
Primary
Secondary
Respiratory Disorder Congenital Anomaly Male 8 lb 7/19/2011 Other Health Professional Germany
Primary
Secondary
Weight Increased Disability 9/1/2010 30 Male 7/19/2011 Physician United Kingdom
Primary
Concomitant
Dysmorphism Other Serious 0 Male 8 lb 7/19/2011 Other Health Professional Germany
Primary
Secondary
Maternal Exposure During Pregnancy Congenital Anomaly 0 Male 8 lb 7/19/2011 Other Health Professional Germany
Primary
Secondary
Sickle Cell Trait Other Serious 5/3/2011 36 Male 7/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Congenital Anomaly Congenital Anomaly 0 Male 8 lb 7/5/2011 Other Health Professional Germany
Primary
Secondary
Diabetic Retinopathy Other Serious Male 7/25/2011 Consumer Canada
Primary
Concomitant
Cardiac Murmur Other Serious 4/1/2011 21 Male 175 lb 8/3/2011 Physician United Kingdom
Primary
Concomitant
Sickle Cell Trait Other Serious 5/3/2011 36 Male 8/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diabetic Nephropathy Other Serious 1/1/2002 30 Male 239 lb 8/3/2011 Consumer United States
Primary
Concomitant
Weight Increased Disability 9/1/2010 30 Male 8/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Dysfunction Other Serious 4/1/2011 21 Male 175 lb 8/5/2011 Physician United Kingdom
Primary
Concomitant
Decreased Appetite Hospitalization 57 Female 8/1/2011 Physician Canada
Primary
Secondary
Concomitant
Aggression Hospitalization Male 8/16/2011 Consumer United States
Primary
Secondary
Bradykinesia Hospitalization 72 Male 9/12/2011 Other Health Professional India
Primary
Secondary
Concomitant
Dyspnoea Other Serious 8/1/2005 47 Female 9/21/2011 Other Health Professional Ireland
Primary
Concomitant
Hallucination, Visual Hospitalization 1/1/2007 72 Male 9/16/2011 Physician India
Primary
Secondary
Concomitant
Neutrophil Count Decreased Death 8/1/2005 47 Female 9/23/2011 Other Health Professional Ireland
Primary
Concomitant
Parkinsonian Rest Tremor Other Serious 1/1/2008 72 Male 9/21/2011 Physician India
Primary
Secondary
Dyspnoea Other Serious 8/1/2005 47 Female 10/7/2011 Other Health Professional Ireland
Primary
Concomitant
Faecaloma Hospitalization Male 143 lb 10/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 82 Female 12/20/2011 Other Health Professional United States
Primary
Secondary
Death Death 82 Female 12/20/2011 Other Health Professional United States
Primary
Secondary
Abnormal Behaviour Hospitalization 1/5/2012 Other Health Professional Turkey
Primary
Concomitant
Psychotic Disorder Hospitalization 1/5/2012 Other Health Professional Turkey
Primary
Concomitant
Electrocardiogram Qt Shortened Other Serious 1/12/2012 22 Male 2/22/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Enuresis Other Serious 30 Male 4/12/2012 Physician United States
Primary
Concomitant
Localised Oedema 52 Female 5/22/2012 Physician United States
Primary
Concomitant
Antipsychotic Drug Level Increased Other Serious 1/11/2012 22 Male 6/25/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Percentage Decreased Other Serious 6/22/2011 9 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Lung Neoplasm Malignant Death 6/27/2011 55 Male 125 lb 6/28/2012 Pharmacist United States
Primary
Concomitant
Death Death 7/21/2011 36 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 9/15/2011 33 Male 148 lb 6/28/2012 Pharmacist United States
Primary
Concomitant
Death Death 9/1/2011 49 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 1/10/2012 47 Female 6/28/2012 Pharmacist United States
Primary
Concomitant
Convulsion Other Serious 1/11/2012 54 Male 168 lb 6/28/2012 Pharmacist United States
Primary
Concomitant
Granulocytopenia Life Threatening 1/27/2012 33 Male 149 lb 6/28/2012 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 2/21/2011 27 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 12/4/2011 25 Male 183 lb 6/28/2012 Pharmacist United States
Primary
Concomitant
Metabolic Syndrome Hospitalization 25 Male 7/2/2012 Physician Netherlands
Primary
Secondary
Concomitant
Metabolic Syndrome Hospitalization 25 Male 6/29/2012 Physician Netherlands
Primary
Secondary
Concomitant
Death Hospitalization Female 207 lb 7/10/2012 Physician Denmark
Primary
Concomitant
Psoriasis Hospitalization 25 Male 7/11/2012 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/10/2012 26 Female 216 lb 8/16/2012 Other Health Professional United Kingdom
Primary
Concomitant
Mental Impairment Death 1/11/2012 22 Male 146 lb 8/17/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Infection Death 56 Male 9/21/2012 Other Health Professional Fi
Primary
Concomitant
Infection Death 53 Female 9/21/2012 Other Health Professional Fi
Primary
Concomitant
Infection Death 62 Female 9/21/2012 Other Health Professional Fi
Primary
Concomitant
Infection Death 58 Female 9/21/2012 Other Health Professional Fi
Primary
Concomitant
Incorrect Route Of Drug Administration 10/2/2012 65 Female 150 lb 10/17/2012 Consumer Us
Primary
Concomitant
Death Death Male 10/19/2012 Other Health Professional Gb
Primary
Concomitant
Pulmonary Oedema Hospitalization Male 9/18/2012 Pharmacist Us
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/25/2012 53 Male 181 lb 7/25/2013 Pharmacist Us
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious Male 8/5/2013 Consumer Us
Primary
Concomitant
Paranoia Other Serious Female 3/12/2013 Physician Us
Primary
Secondary
Concomitant
Quality Of Life Decreased Other Serious 25 Male 3/14/2013 Other Health Professional Country Not Specified
Primary
Secondary
Neutropenia Other Serious 40 Female 3/28/2013 Other Health Professional Tw
Primary
Concomitant
Suicidal Ideation Hospitalization Female 6/18/2013 Physician Us
Primary
Concomitant
Vomiting Hospitalization 9/3/2013 16 Male 128 lb 9/13/2013 Pharmacist Us
Primary
Concomitant
Suicide Attempt Other Serious 42 Female 10/3/2013 Other Health Professional Gr
Primary
Secondary

Drug Data