Clozapine combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ileus Paralytic Other Serious 34 Male 172 lb 1/25/2006 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/17/2005 44 Male 2/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Death 11/28/2005 44 Male 352 lb 2/9/2006 Physician United States
Primary
Concomitant
Menorrhagia Hospitalization 10/2/2005 47 Female 2/15/2006 United States
Primary
Concomitant
Death Death 1/10/2006 62 Male 2/27/2006 United States
Primary
Concomitant
Pyrexia Hospitalization 12/15/2005 56 Male 3/3/2006 France
Primary
Concomitant
Neutropenia Other Serious 2/27/2006 50 Male 3/9/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Ileus Paralytic Other Serious 11/15/2005 34 Male 172 lb 3/11/2006 United Kingdom
Primary
Secondary
Concomitant
Death Death 2/13/2006 44 Male 3/8/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2005 39 Male 3/24/2006 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 2/1/2005 39 Male 4/26/2006 Pharmacist United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/8/2006 United States
Primary
Concomitant
Pyrexia Other Serious 8/16/2005 82 Male 5/24/2006 France
Primary
Concomitant
Death Death 5/14/2006 57 Female 5/22/2006 United States
Primary
Concomitant
Psychotic Disorder Required Intervention 4/10/2006 44 Male 6/5/2006 United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 9/21/2005 35 Male 6/12/2006 United Kingdom
Primary
Secondary
Concomitant
Death Death 5/14/2006 57 Female 6/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/10/2005 45 Female 1/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/9/2005 50 Male 3/22/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/10/2006 43 Male 6/14/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 9/29/2005 24 Male 192 lb 2/3/2006 Consumer United States
Primary
Concomitant
Overdose Life Threatening 5/5/2006 37 Female 8/17/2006 United Kingdom
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 3/8/2006 61 Female 4/10/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 3/1/2006 60 Female 5/18/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/23/2005 55 Male 2/27/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 9/30/2005 62 Female 1/18/2006 United States
Primary
Concomitant
Hypoglycaemic Coma Death 6/12/2006 49 Male 8/24/2006 United States
Primary
Concomitant
Death Death 7/29/2006 60 Male 9/7/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 10/4/2006 United States
Primary
Concomitant
Postictal State Other Serious 7/13/2006 42 Female 1/3/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/27/2006 Male 184 lb 1/29/2007 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 11/24/2006 54 Male 2/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 4/23/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/17/2007 United States
Primary
Concomitant
Urinary Incontinence Other Serious 12/28/2005 41 Male 182 lb 4/2/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/31/2007 United States
Primary
Concomitant
Leukocytosis 5/23/2007 60 Male 169 lb 5/31/2007 Pharmacist United States
Primary
Concomitant
Speech Disorder Hospitalization 6/17/2007 75 Male 141 lb 8/7/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Overdose Life Threatening 5/5/2006 37 Female 8/10/2007 United Kingdom
Primary
Secondary
Concomitant
Hyperthyroidism Other Serious 18 Male 120 lb 8/20/2007 Physician United States
Primary
Concomitant
Psychotic Disorder Death 6/1/2007 Male 195 lb 10/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 36 Male 11/12/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 10/5/2007 49 Male 162 lb 11/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Regimen Changed 12/2/2005 32 Female 348 lb 12/2/2005 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/25/2008 51 Male 4/23/2008
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/25/2008 51 Male 4/25/2008
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/25/2008 51 Male 4/29/2008
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/1/2008 46 Male 5/5/2008 Physician Belgium
Primary
Secondary
Concomitant
Surgery Other Serious 1/1/2006 44 Male 209 lb 5/29/2008 Consumer Brazil
Primary
Concomitant
Somnolence Other Serious Female 6/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious Female 7/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Disability 6/27/2008 7/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious Female 7/14/2008 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious Female 7/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 6/27/2008 7/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Grand Mal Convulsion Disability 6/27/2008 29 Male 192 lb 7/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Grand Mal Convulsion Disability 6/27/2008 29 Male 192 lb 7/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Disability 6/27/2008 29 Male 7/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Obesity Other Serious 6/12/2008 Female 322 lb 8/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Failure Death 54 Male 8/14/2008 Other Health Professional France
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 6/27/2008 8/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 6/27/2008 29 Male 192 lb 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 8/12/2008 Male 9/9/2008 Consumer South Africa
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 63 Male 9/22/2008 Consumer Israel
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 1/13/2008 Male 360 lb 10/8/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 8/3/2008 49 Male 212 lb 12/19/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased 6/6/2008 33 Male 212 lb 6/9/2008 Pharmacist United States
Primary
Concomitant
Retinopathy Other Serious 55 Female 3/5/2009 Physician Australia
Primary
Concomitant
Retinal Pigmentation Disability 55 Female 3/16/2009 Physician Australia
Primary
Concomitant
Drug Interaction Other Serious 44 Male 3/31/2009 Other Health Professional New Zealand
Primary
Interacting
Loss Of Consciousness Other Serious 32 Male 3/31/2009 Other Health Professional New Zealand
Primary
Interacting
Grand Mal Convulsion Hospitalization 10/22/1998 45 Male 5/12/2009 Physician New Zealand
Primary
Concomitant
Interacting
Phaeochromocytoma Other Serious 4/21/2008 Female 136 lb 7/1/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/2/2006 62 Female 359 lb 7/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/9/2009 Female 117 lb 7/20/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Subileus Death 1/11/2009 68 Female 117 lb 7/29/2009 Physician Germany
Primary
Secondary
Subileus Death 1/11/2009 68 Female 117 lb 7/30/2009 Physician Germany
Primary
Secondary
Type 2 Diabetes Mellitus Hospitalization 2/4/2006 59 Male 348 lb 7/31/2009 United States
Primary
Concomitant
Hyponatraemia Hospitalization 10/12/2008 48 Male 8/3/2009 Physician Australia
Primary
Secondary
Concomitant
Subileus Death 1/11/2009 68 Female 117 lb 7/27/2009 Physician Germany
Primary
Secondary
Drug Interaction Hospitalization Male 8/4/2009 Other Health Professional United Kingdom
Primary
Interacting
Subileus Death 1/11/2009 68 Female 117 lb 8/5/2009 Other Health Professional Germany
Primary
Secondary
Subileus Death 1/11/2009 68 Female 8/10/2009 Physician France
Primary
Secondary
Drug Interaction Hospitalization Male 8/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Treatment Noncompliance Other Serious 60 Male 8/3/2009 United Kingdom
Primary
Secondary
Treatment Noncompliance Hospitalization Male 8/12/2009 United Kingdom
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Other Serious 5/7/2003 18 Female 180 lb 9/23/2009 United States
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 8/30/2009 31 Male 10/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Subileus Other Serious 1/11/2009 68 Female 117 lb 10/12/2009 Pharmacist Germany
Primary
Secondary
Platelet Count Decreased Hospitalization 7/31/2009 52 Male 10/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 10/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 10/14/2009 Other Health Professional France
Primary
Secondary
Concomitant
Subileus Other Serious 1/1/2009 68 Female 117 lb 10/19/2009 Pharmacist United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Ileus Hospitalization 1/9/2009 Female 10/23/2009 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/26/2009 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 9/10/2009 40 Female 10/26/2009 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Syncope Other Serious 7/31/2009 52 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Salivary Hypersecretion Hospitalization 7/31/2009 52 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/10/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 7/31/2009 52 Male 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 7/31/2009 52 Male 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 11/13/2009 United Kingdom
Primary
Concomitant
Russell's Viper Venom Time Abnormal Other Serious 2/1/2007 48 Male 11/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 7/31/2009 52 Male 11/19/2009
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/30/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 12/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ultrafiltration Failure Other Serious 1/1/2009 74 Male 12/23/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/18/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/28/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 1/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/4/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 12/27/2009 58 Female 265 lb 2/8/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Overdose 5/1/2009 Female 104 lb 2/4/2010 Consumer United States
Primary
Concomitant
Weight Increased 6/6/2008 33 Male 212 lb 6/9/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 22 Male 2/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Laparotomy Life Threatening 52 Female 3/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Drug Level Increased Life Threatening 3/3/2010 40 Male 254 lb 4/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Nightmare Hospitalization 2/1/2010 52 Male 4/23/2010 United States
Primary
Concomitant
Drug Level Increased Life Threatening 3/3/2010 40 Male 254 lb 5/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pneumonia Other Serious 60 Male 5/3/2010 United Kingdom
Primary
Secondary
Concomitant
Leukopenia Other Serious 4/30/2009 83 Female 6/24/2010 Physician United States
Primary
Concomitant
Death Death 64 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 36 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 54 Male 150 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 83 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 71 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/19/2009 74 Female 186 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 45 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Choking Death 8/25/2009 59 Male 6/24/2010 Other Health Professional United States
Primary
Concomitant
Granulocytopenia Other Serious 9/27/2009 34 Male 240 lb 6/24/2010 United States
Primary
Secondary
Concomitant
Death Death 10/10/2009 51 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 20 Male 146 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 12/14/2009 59 Male 6/24/2010 Physician United States
Primary
Concomitant
Death Death 36 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 2/5/2010 38 Female 218 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Death Death 2/10/2010 56 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 3/9/2010 57 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 4/12/2010 25 Male 143 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 4/13/2010 59 Male 6/24/2010 Pharmacist United States
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 4/5/2010 30 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Epilepsy Death 220 lb 7/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Mass Other Serious 48 Male 159 lb 7/9/2010 Other Health Professional United States
Primary
Concomitant

Drug Data