Clozapine combined with Olanzapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 2/5/2000 27 Male 12/23/2005 Australia
Primary
Concomitant
Pericardial Effusion Life Threatening 9/30/2005 58 Male 177 lb 12/22/2005 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/17/2005 44 Male 2/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pericardial Effusion Life Threatening 9/30/2005 58 Male 177 lb 12/22/2005 Pharmacist United States
Primary
Concomitant
Shock Life Threatening 19 Male 143 lb 2/21/2006 Physician France
Primary
Concomitant
Neutrophil Count Decreased 12/22/2005 39 Male 2/12/2006 United Kingdom
Primary
Concomitant
Weight Decreased Death 5/3/2005 49 Male 217 lb 3/16/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/18/2005 36 Female 126 lb 12/14/2005 Physician United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 8/23/2005 50 Male 201 lb 12/14/2005 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/2/2005 33 Female 192 lb 2/2/2005 Pharmacist United States
Primary
Concomitant
Intestinal Obstruction Required Intervention 8/20/2005 52 Male 213 lb 12/14/2005 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 61 Male 4/6/2006 Canada
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Death 4/1/2006 56 Male 4/21/2006 United States
Primary
Concomitant
Tachypnoea Other Serious 36 Female 5/5/2006 Other Health Professional United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death 4/1/2006 56 Male 150 lb 5/15/2006 Consumer United States
Primary
Concomitant
Neutrophil Count Decreased 10/1/2004 27 Female 5/15/2006 United Kingdom
Primary
Concomitant
Failure To Thrive Death 5/15/2006 58 Male 5/31/2006 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 32 Male 6/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 34 Male 7/17/2006 France
Primary
Secondary
Concomitant
Interacting
Rash Macular Other Serious 34 Male 7/21/2006 France
Primary
Concomitant
Granulocytopenia Required Intervention 12/23/2005 69 Male 4/4/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/2/2006 49 Male 3/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/31/2006 59 Male 4/3/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/9/2005 29 Male 155 lb 6/20/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 9/19/2005 44 Female 1/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/3/2005 42 Male 1/25/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/14/2005 47 Male 6/16/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 11/15/2004 45 Male 190 lb 6/16/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/6/2005 50 Male 201 lb 3/7/2006 Consumer United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 11/16/2005 37 Male 210 lb 2/14/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/24/2005 79 Female 2/13/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/11/2005 30 Male 191 lb 3/2/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/7/2005 46 Male 141 lb 2/14/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 8/17/2005 33 Male 1/5/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/12/2005 49 Male 220 lb 1/16/2006 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Required Intervention 7/6/2006 35 Female 172 lb 7/25/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 31 Male 7/21/2006 Physician India
Primary
Concomitant
Granulocytopenia 1/3/2006 60 Male 5/9/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/30/2006 43 Male 118 lb 5/15/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/8/2006 31 Male 220 lb 4/19/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 9/12/2005 50 Male 1/6/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 11/2/2005 43 Male 196 lb 6/16/2006 Consumer United States
Primary
Concomitant
Death Death 7/4/2006 36 Male 8/16/2006 United States
Primary
Concomitant
Completed Suicide Death 7/3/2006 73 Male 148 lb 8/24/2006 Physician Russian Federation
Primary
Concomitant
Parkinson's Disease Death 9/17/2006 54 Female 10/2/2006 United States
Primary
Concomitant
Dysphagia Death 9/17/2006 54 Female 10/23/2006 United States
Primary
Concomitant
Somnolence Other Serious 64 Female 11/7/2006 Other Health Professional Netherlands
Primary
Secondary
Gastrointestinal Haemorrhage 11/5/2006 58 Male 137 lb 11/15/2006 Consumer China
Primary
Concomitant
Postictal State Hospitalization 10/11/2006 18 Female 11/22/2006 Pharmacist United States
Primary
Concomitant
Intentional Overdose Other Serious 35 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Somnolence Other Serious Male 1/4/2007 Consumer Ireland
Primary
Secondary
Troponin Increased Hospitalization 12/13/2006 51 Male 297 lb 12/29/2006 Pharmacist United States
Primary
Concomitant
Posture Abnormal Other Serious 52 Female 1/19/2007 Other Health Professional Spain
Primary
Secondary
Urine Output Decreased Other Serious 1/1/2007 21 Male 2/7/2007 Consumer Australia
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 10/20/2006 40 Female 2/14/2007 United Kingdom
Primary
Secondary
White Blood Cell Count Increased Life Threatening 10/20/2006 40 Female 2/14/2007 United Kingdom
Primary
Secondary
Urine Output Decreased Other Serious 1/1/2007 21 Male 2/16/2007 Consumer Australia
Primary
Concomitant
Vomiting Hospitalization 62 Male 2/22/2007 Other Health Professional Hungary
Primary
Concomitant
Neutropenia Other Serious 36 Female 3/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Weight Increased Other Serious 33 Female 168 lb 3/14/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Weight Increased Other Serious 33 Female 168 lb 4/6/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2000 43 Male 4/28/2007 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Other Serious 60 Female 5/1/2007 Germany
Primary
Secondary
Prescribed Overdose Other Serious 32 Male 5/18/2007 Physician Brazil
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/1/2006 32 Female 5/31/2007 Physician Australia
Primary
Interacting
Urinary Incontinence Other Serious 12/28/2005 41 Male 182 lb 4/2/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 34 Male 6/22/2007 France
Primary
Secondary
Concomitant
Interacting
Splenomegaly Other Serious 10/19/2006 31 Male 7/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2007 53 Male 7/5/2007 Physician United States
Primary
Concomitant
Haemolytic Anaemia Other Serious 16 Female 7/11/2007 Physician United Kingdom
Primary
Concomitant
Splenomegaly Other Serious 9/1/2002 31 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 16 Female 8/10/2007 Physician United Kingdom
Primary
Concomitant
Drug Ineffective Hospitalization 7/24/2007 Male 9/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/1/2006 39 Male 9/11/2007 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/29/2000 41 Female 148 lb 9/18/2007 Physician United States
Primary
Concomitant
Diabetes Mellitus 1/1/2006 49 Male 192 lb 9/18/2007 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Life Threatening 11/18/2006 Male 9/21/2007 Other Health Professional France
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2007 Male 10/9/2007 Physician Italy
Primary
Concomitant
Septic Shock Death 34 Male 10/29/2007 Physician United Kingdom
Primary
Concomitant
Dry Eye Other Serious 8/1/2003 17 Male 11/2/2007 Physician Switzerland
Primary
Concomitant
Septic Shock Death 1/1/2001 Male 11/7/2007 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 62 Male 11/13/2007 Physician Hungary
Primary
Concomitant
Dry Eye Other Serious 8/1/2003 17 Male 11/30/2007 Physician Switzerland
Primary
Concomitant
White Blood Cell Count Decreased 55 Male 12/10/2007 Physician United States
Primary
Concomitant
Tremor Required Intervention 5/18/2007 28 Male 170 lb 5/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Dry Eye Other Serious 8/1/2003 17 Male 12/29/2007 Physician Switzerland
Primary
Concomitant
Pleurothotonus Other Serious 39 Female 1/7/2008 France
Primary
Secondary
Interacting
Somnolence Hospitalization 1/16/2008 Other Health Professional China
Primary
Secondary
Torticollis Other Serious 59 Male 3/14/2008 Other Health Professional United States
Primary
Secondary
Waxy Flexibility Other Serious 31 Male 3/24/2008 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 74 Female 3/17/2008 Physician Netherlands
Primary
Concomitant
Weight Increased Hospitalization 1/1/2000 15 Male 4/7/2008 Consumer United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 3/19/2007 Male 4/11/2008 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 46 Female 4/11/2008 Brazil
Primary
Secondary
Myocarditis Hospitalization 4/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Required Intervention 64 Female 4/30/2008 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 5/21/2008 58 Male 6/24/2008 Other Health Professional United States
Primary
Secondary
Somnolence Hospitalization 5/21/2008 58 Male 6/26/2008 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Life Threatening 53 Male 7/17/2008 Australia
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 53 Male 7/25/2008 Australia
Primary
Secondary
Concomitant
Somnolence Hospitalization Female 8/5/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 55 Male 8/25/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/1/2007 22 Male 9/24/2008 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 5/21/2008 58 Male 10/23/2008 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 7/28/2008 Female 10/29/2008 Physician France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/23/2008 62 Male 11/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sedation Hospitalization 1/1/2005 32 Male 12/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/21/2008 Female 165 lb 12/12/2008 Pharmacist United States
Primary
Concomitant
Psychotic Disorder Hospitalization 1/1/2005 32 Male 12/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 28 Female 12/29/2008 Physician Hong Kong
Primary
Secondary
Varicose Vein Hospitalization 12/16/2008 Female 1/2/2009 Physician New Zealand
Primary
Concomitant
Torticollis Hospitalization 35 Male 12/23/2008 Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 10/14/2008 Male 2/10/2009 Physician United States
Primary
Secondary
Concomitant
Pleurothotonus Disability 67 Male 2/5/2009 Physician Argentina
Primary
Secondary
Concomitant
Mania Other Serious 22 Male 2/27/2009 Consumer United States
Primary
Secondary
Xanthoma Hospitalization 23 Male 3/6/2009 Physician Ireland
Primary
Secondary
Concomitant
Suspiciousness Other Serious 37 Male 3/26/2009 Physician Taiwan, Province Of China
Primary
Secondary
Pleural Effusion Hospitalization 64 Female 6/5/2009 United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 64 Female 6/5/2009 United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 2/1/2008 Female 6/1/2009 Physician Norway
Primary
Concomitant
Productive Cough Hospitalization 64 Female 6/16/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/25/2000 41 Female 162 lb 6/18/2009 United States
Primary
Concomitant
Pleural Effusion Other Serious 64 Female 7/9/2009 Physician United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 10/14/2008 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 10/14/2008 53 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 7/28/2009 23 Male 8/6/2009 Physician China
Primary
Concomitant
Somnolence Death Female 8/4/2009 Physician Canada
Primary
Concomitant
Drug Ineffective Death 7/8/2009 23 Male 8/11/2009 Physician China
Primary
Concomitant
Pulmonary Eosinophilia Hospitalization 64 Female 8/6/2009 Physician Spain
Primary
Concomitant
Pleural Effusion Other Serious 64 Female 8/20/2009 Physician Spain
Primary
Concomitant
Weight Increased Other Serious 16 Male 9/3/2009
Primary
Secondary
Concomitant
Weight Increased Other Serious 16 9/11/2009 Other Health Professional Turkey
Primary
Secondary
Psychotic Disorder Other Serious 47 Female 9/16/2009 Other Health Professional Spain
Primary
Concomitant
Schizoaffective Disorder Other Serious 29 Male 10/2/2009
Primary
Secondary
Visual Impairment Other Serious 38 Male 11/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Oculogyric Crisis Hospitalization Female 11/11/2009 Physician Germany
Primary
Secondary
Weight Increased Other Serious 16 Male 11/18/2009 Other Health Professional Turkey
Primary
Secondary
Thrombocytopenia Other Serious 1/1/2007 Male 11/30/2009 Physician Italy
Primary
Concomitant
Septic Shock Death 1/1/2001 Male 11/30/2009 Physician United Kingdom
Primary
Concomitant
Haemolytic Anaemia Other Serious 16 Female 12/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myoclonus Other Serious Male 1/21/2010 Other Health Professional United States
Primary
Secondary
Myoclonus Other Serious Male 1/22/2010 Other Health Professional United States
Primary
Secondary
Weight Increased Hospitalization 4/5/2008 18 Male 1/25/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Vomiting Death 1/6/2008 Female 2/5/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Sedation 4/16/2009 59 Female 136 lb 7/21/2009 Pharmacist United States
Primary
Secondary
Concomitant
Restlessness Other Serious Male 3/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 Female 3/4/2010 Pharmacist United Kingdom
Primary
Concomitant
Restlessness Other Serious 41 Male 3/5/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 24 Male 3/9/2010 Physician Germany
Primary
Concomitant
Myoclonus Hospitalization 38 Male 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data