Clozapine combined with Mirtazapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Disorder Death 1/1/2006 90 Female 5/22/2006 United States
Primary
Concomitant
Aortic Dissection Death 1/1/2006 90 Female 6/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/15/2005 13 Male 6/1/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/25/2006 64 Female 4/11/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 2/7/2006 45 Male 6/1/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/28/2005 73 Male 1/18/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/23/2005 44 Male 4/25/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/12/2005 44 Female 1/30/2006 Consumer United States
Primary
Concomitant
Type Ii Hypersensitivity Death 34 Female 7/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Leukopenia Required Intervention 3/13/2006 73 Male 5/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Death 1/1/2006 56 Male 9/18/2006 United States
Primary
Concomitant
Neutrophil Count Decreased Death 10/5/2006 76 Male 10/16/2006 United States
Primary
Concomitant
Neutrophil Count Decreased Death 10/5/2006 76 Male 11/20/2006 Consumer United States
Primary
Concomitant
Posture Abnormal Other Serious 52 Female 1/19/2007 Other Health Professional Spain
Primary
Secondary
Pyrexia Hospitalization Male 3/14/2007 Physician Italy
Primary
Concomitant
Wheezing Other Serious 1/4/2007 36 Male 3/21/2007 Physician Italy
Primary
Concomitant
Prescribed Overdose Hospitalization 1/1/2003 38 Male 250 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2000 28 Male 253 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 5/1/2005 40 Female 233 lb 9/17/2007 Other Health Professional United States
Primary
Secondary
Metabolic Syndrome Other Serious 1/1/2003 31 Male 227 lb 10/9/2007 Lawyer United States
Primary
Concomitant
Suicidal Ideation Hospitalization 7/1/2005 Female 156 lb 1/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 9/20/2007 72 Female 2/13/2008 Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 2/28/2008 41 Male 4/16/2008 Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/19/2008 44 Male 4/21/2008 Germany
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 2/28/2008 41 Male 5/5/2008 Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/19/2008 44 Male 9/5/2008 Physician Germany
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 3/28/2008 36 Male 11/4/2008 France
Primary
Secondary
Tonsillitis Hospitalization 3/28/2008 36 Male 11/12/2008 France
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization 2/19/2008 Female 11/25/2008 Other Health Professional Germany
Primary
Secondary
Mental Disorder Hospitalization Female 12/3/2008 Germany
Primary
Concomitant
Personality Disorder Hospitalization 55 Male 12/15/2008
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 2/11/2008 48 Female 1/21/2009 Germany
Primary
Secondary
Tardive Dyskinesia Hospitalization 2/1/2003 Female 2/19/2009 Physician United Kingdom
Primary
Concomitant
Unresponsive To Stimuli 2/6/2009 84 Female 3/6/2009 Portugal
Primary
Secondary
Urinary Retention Hospitalization 2/9/2009 59 Male 152 lb 4/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Suprapubic Pain Hospitalization 2/7/2009 59 Male 3/31/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 2/6/2009 84 Female 6/17/2009 Portugal
Primary
Secondary
Parkinson's Disease 4/1/2009 Male 287 lb 7/22/2009 Physician United States
Primary
Concomitant
Malaise Hospitalization Female 9/7/2009 Consumer United Kingdom
Primary
Secondary
Pulmonary Embolism Death 4/22/2009 34 Male 271 lb 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/22/2009 34 Male 10/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Death 4/22/2009 34 Male 271 lb 11/2/2009
Primary
Secondary
Concomitant
Death Death 9/15/2009 Male 11/16/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Russell's Viper Venom Time Abnormal Other Serious 2/1/2007 48 Male 11/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 12/27/2009 58 Female 265 lb 2/8/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Treatment Failure Other Serious 49 Male 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 49 Male 5/17/2010 Other Health Professional United States
Primary
Secondary
Failure To Thrive Other Serious 92 Female 90 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 54 Male 150 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 8/17/2009 54 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Choking Death 8/25/2009 59 Male 6/24/2010 Other Health Professional United States
Primary
Concomitant
Epilepsy Death 220 lb 7/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 4/29/2010 65 Female 7/28/2010 Physician Switzerland
Primary
Secondary
Concomitant
Nerve Compression Hospitalization 1/1/2008 58 Female 190 lb 7/26/2010 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Other Serious 4/29/2010 65 Female 7/29/2010 Physician Switzerland
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/3/2010 86 Female 7/23/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Fall Hospitalization 4/1/2008 58 Female 190 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Epilepsy Death 26 Male 220 lb 8/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/3/2010 86 Female 8/12/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 49 Male 9/17/2010 Pharmacist United States
Primary
Secondary
Concomitant
Overdose Hospitalization 10/8/2010 24 Male 11/2/2010 Other Health Professional Denmark
Primary
Secondary
Urinary Tract Infection Other Serious Female 11/18/2010 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious Female 12/7/2010 Pharmacist United Kingdom
Primary
Concomitant
Device Failure Other Serious 1/1/2011 Female 5/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Insipidus Hospitalization 3/17/2011 55 Female 5/23/2011 Other Health Professional France
Primary
Secondary
Myoclonus Hospitalization 3/17/2011 55 Female 5/23/2011 Other Health Professional France
Primary
Secondary
Renal Failure Acute Hospitalization 3/17/2011 55 Female 5/18/2011 Physician France
Primary
Secondary
Antisocial Behaviour Other Serious 3/23/2009 16 Male 6/8/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Ulcer Hospitalization 7/15/2005 26 Male 6/4/2011 Consumer United Kingdom
Primary
Concomitant
Diabetes Mellitus Other Serious Female 6/4/2011 Physician United Kingdom
Primary
Concomitant
Sinus Tachycardia Hospitalization 4/19/2006 50 Male 6/4/2011 Physician Australia
Primary
Concomitant
Neutrophil Count Increased Death Male 6/4/2011 Physician United Kingdom
Primary
Concomitant
Death Death 3/10/2008 40 Male 6/8/2011 Physician Canada
Primary
Concomitant
Malaise Other Serious 2/20/2008 51 Male 6/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Other Serious 12/16/2006 44 Male 6/5/2011 Pharmacist United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 3/23/2009 16 Male 6/9/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/27/2003 67 Female 6/13/2011 Consumer United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 3/22/2006 54 Male 6/14/2011 Consumer United Kingdom
Primary
Concomitant
Incorrect Dose Administered Hospitalization 3/18/2011 51 Male 6/15/2011 Physician United Kingdom
Primary
Concomitant
Tachycardia Hospitalization Female 6/15/2011 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious Female 6/16/2011 Physician United Kingdom
Primary
Concomitant
Hemiparesis Disability 2/1/2007 47 Male 6/16/2011 Consumer United Kingdom
Primary
Concomitant
Mental Impairment Hospitalization Female 6/17/2011 Physician United Kingdom
Primary
Concomitant
Granulocytopenia Other Serious 1/4/2011 22 Male 230 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Multi-organ Failure Death 12/31/2010 51 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Other Serious 2/8/2011 69 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 3/2/2011 58 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 1/1/2011 78 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Neutropenia Other Serious 28 Male 6/17/2011
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/6/2010 52 Female 6/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Other Serious 3/23/2009 16 Male 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 10/6/2010 52 Female 6/28/2011 Physician United Kingdom
Primary
Concomitant
Blood Pressure Decreased Other Serious 4/22/2011 85 Female 6/28/2011 Physician Canada
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2008 16 Male 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 4/15/2011 28 Male 6/23/2011 Other Health Professional
Primary
Concomitant
Incorrect Dose Administered Hospitalization 3/18/2011 51 Male 7/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Leukaemia Other Serious 7/6/2010 49 Female 7/11/2011 Physician United Kingdom
Primary
Concomitant
Hyperhidrosis Hospitalization 3/23/2009 16 Male 7/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Accidental Poisoning Death 46 7/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Haemoglobin Decreased Hospitalization 7/1/1995 46 Female 7/14/2011 Physician Ireland
Primary
Concomitant
Extrapyramidal Disorder Other Serious 1/1/2008 16 Male 7/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 5/12/2011 39 Male 7/8/2011 Pharmacist United Kingdom
Primary
Concomitant
Syncope Other Serious 1/31/2011 65 Male 7/19/2011 Physician Ireland
Primary
Concomitant
Psychotic Disorder Hospitalization 2/1/2011 85 Female 7/22/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Drug Administration Error Other Serious 5/12/2011 39 Male 7/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Social Avoidant Behaviour Hospitalization 9/1/2010 38 Female 7/25/2011 Physician Ireland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2010 38 Female 7/25/2011 Physician Ireland
Primary
Secondary
Concomitant
Extrapyramidal Disorder Hospitalization 1/1/2008 16 Male 7/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 5/12/2011 39 Male 7/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Dose Omission Other Serious 39 Male 7/20/2011 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/23/2009 16 Male 7/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 5/12/2011 39 Male 7/26/2011 Other Health Professional Denmark
Primary
Concomitant
Cardiac Murmur Other Serious 4/1/2011 21 Male 175 lb 8/3/2011 Physician United Kingdom
Primary
Concomitant
Product Packaging Quantity Issue Other Serious 5/12/2011 39 Male 7/27/2011 Pharmacist United Kingdom
Primary
Concomitant
Ventricular Dysfunction Other Serious 4/1/2011 21 Male 175 lb 8/5/2011 Physician United Kingdom
Primary
Concomitant
Lymphocyte Count Increased Other Serious 7/6/2010 49 Female 8/9/2011 Physician United Kingdom
Primary
Concomitant
Pneumonia Life Threatening 12/30/2007 82 Male 8/10/2011 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Life Threatening 12/31/2007 82 Male 8/15/2011 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/4/2011 59 Female 8/16/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Increased Other Serious 4/4/2011 59 Female 8/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fatigue Other Serious 12/30/2007 82 Male 8/16/2011 Physician Germany
Primary
Secondary
Concomitant
Antisocial Behaviour Hospitalization 1/1/2008 16 Male 8/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Self Esteem Decreased Life Threatening 7/22/2010 37 Male 8/23/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Self Esteem Decreased Hospitalization 7/22/2010 37 Male 8/23/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 1/1/1994 45 Female 8/24/2011 Physician Ireland
Primary
Concomitant
Nausea Other Serious 5/12/2011 39 Male 8/18/2011 Pharmacist United Kingdom
Primary
Concomitant
Cardio-respiratory Arrest Life Threatening 7/19/2011 77 Female 8/30/2011 Other Health Professional France
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 4/4/2011 59 Female 9/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 4/4/2011 59 Female 9/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oropharyngeal Pain Other Serious 4/4/2011 59 Female 9/6/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/4/2011 59 Female 9/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 8/28/2011 39 Female 9/8/2011 Physician United Kingdom
Primary
Concomitant
Product Packaging Issue Other Serious 5/12/2011 39 Male 9/8/2011 Pharmacist United Kingdom
Primary
Concomitant
Nausea Other Serious 5/12/2011 39 Male 9/7/2011 Pharmacist United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 6/20/2011 62 Female 9/8/2011 Other Health Professional Ireland
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/4/2011 59 Female 9/19/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Sedation Death 7/25/2006 78 Male 9/19/2011 Other Health Professional Denmark
Primary
Concomitant
Neutrophil Count Decreased Other Serious 4/4/2011 59 Female 9/19/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/1994 45 Female 9/12/2011 Physician Ireland
Primary
Concomitant
Blood Glucose Decreased Other Serious 1/1/1998 27 Male 201 lb 9/22/2011 United States
Primary
Concomitant
Leukaemia Other Serious 7/6/2010 49 Female 9/22/2011 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/4/2011 59 Female 9/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lymphocyte Count Increased Other Serious 7/6/2010 49 Female 9/29/2011 Other Health Professional United Kingdom
Primary
Concomitant
Death Death Male 10/3/2011 Other Health Professional Ireland
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 1/29/2010 61 Male 196 lb 10/5/2011 Other Health Professional Ireland
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 1/29/2010 61 Male 196 lb 10/11/2011 Other Health Professional Ireland
Primary
Concomitant
Tachycardia Other Serious 7/12/2011 24 Male 10/13/2011 Physician Denmark
Primary
Secondary
Muscle Twitching Other Serious 9/17/2011 31 Male 10/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 9/17/2011 31 Male 10/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Back Pain Other Serious 6/27/2003 40 Male 10/31/2011 Physician Australia
Primary
Secondary
Concomitant

Drug Data