Clozapine combined with Lithium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
X-ray Gastrointestinal Tract Abnormal Life Threatening 10/31/2005 44 Female 1/13/2006 Physician United Kingdom
Primary
Concomitant
Aneurysm Death 43 Male 1/11/2006 United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 5/31/2005 Male 1/17/2006 Australia
Primary
Secondary
Loss Of Consciousness Hospitalization 51 Female 2/9/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 2/28/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Male 3/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/8/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2006 45 Female 170 lb 3/7/2006 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/10/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 8/5/2005 19 Female 12/14/2005 Other Health Professional United States
Primary
Concomitant
Myoclonus Hospitalization 8/26/2005 43 Female 12/14/2005 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 17 Female 3/28/2006 Physician Chile
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Female 3/27/2006 United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased 2/27/2006 Male 175 lb 4/3/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 61 Male 4/6/2006 Canada
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 2/3/2006 43 Female 183 lb 4/3/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/19/2005 48 Male 3/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/17/2006 35 Male 4/4/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 1/20/2005 53 Female 6/21/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/5/2006 18 Male 6/1/2006 United States
Primary
Concomitant
Neoplasm Malignant Death 7/4/2006 78 Male 7/24/2006 United States
Primary
Concomitant
Treatment Noncompliance Death 7/8/2006 45 Male 7/26/2006 United States
Primary
Concomitant
Tooth Abscess Other Serious 51 Male 203 lb 8/7/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Small Cell Carcinoma Death 7/26/2006 45 Female 8/9/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/3/2005 31 Male 1/9/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 9/12/2005 60 Male 156 lb 1/9/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 2/28/2006 25 Female 4/18/2006 United States
Primary
Concomitant
Death Death 7/4/2006 36 Male 8/16/2006 United States
Primary
Concomitant
Small Cell Carcinoma Death 7/26/2006 45 Female 8/31/2006 United States
Primary
Concomitant
Pyrexia 8/18/2007 36 Male 195 lb 8/18/2007 Pharmacist United States
Primary
Concomitant
Renal Disorder Other Serious 36 Male 12/31/2007 Italy
Primary
Interacting
Staring Other Serious 7/17/2008 Physician Germany
Primary
Concomitant
Viral Myocarditis Hospitalization 3/3/2008 21 Female 12/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Varicose Vein Hospitalization 12/16/2008 Female 1/2/2009 Physician New Zealand
Primary
Concomitant
Tremor Other Serious 41 Male 1/21/2009 Other Health Professional United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/21/2009 Female 2/13/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 10/14/2008 53 Male 2/16/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 2/2/2009 Male 295 lb 3/26/2009 Other Health Professional United States
Primary
Secondary
Tachypnoea Other Serious 28 Male 3/26/2009 France
Primary
Secondary
Vomiting Other Serious 44 Female 5/15/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 4/1/2009 Female 5/19/2009 Other Health Professional United States
Primary
Secondary
Metabolic Acidosis Other Serious Male 5/20/2009 Physician
Primary
Concomitant
Treatment Noncompliance Other Serious 2/17/2009 40 Male 5/22/2009 Physician United States
Primary
Secondary
Concomitant
Influenza Other Serious 4/10/2009 51 Female 7/3/2009 Pharmacist United States
Primary
Concomitant
Overdose Other Serious 12/15/2006 Male 142 lb 7/6/2009 Physician United States
Primary
Concomitant
Granulocytopenia Other Serious 10/14/2008 53 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious Male 7/31/2009 Physician
Primary
Concomitant
Somnolence Other Serious 3/1/2007 42 Male 8/3/2009 Physician India
Primary
Secondary
Concomitant
Granulocytopenia 10/23/2008 Female 8/6/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 29 Male 11/2/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Interacting
Visual Impairment Other Serious 38 Male 11/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myoclonus Other Serious Male 1/21/2010 Other Health Professional United States
Primary
Secondary
Myoclonus Other Serious Male 1/22/2010 Other Health Professional United States
Primary
Secondary
Mental Status Changes 1/27/2009 25 Female 125 lb 2/17/2009 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 38 Male 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 38 Male 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Laboratory Test Abnormal Other Serious 3/18/2010 46 Male 185 lb 3/19/2010 Pharmacist United States
Primary
Concomitant
Tardive Dyskinesia Other Serious Male 4/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 5/30/2010 65 Female 131 lb 6/11/2010 Pharmacist United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 28 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 14 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 15 Male 6/24/2010 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 9 Female 81 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 9/15/2009 60 Female 6/24/2010 Physician United States
Primary
Concomitant
Respiratory Arrest Death 8/13/2009 44 Male 160 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 8/20/2009 53 Male 231 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 10/5/2009 12 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 11/13/2009 12 Male 6/24/2010 Physician United States
Primary
Concomitant
Leukopenia Other Serious 11/17/2009 55 Male 6/24/2010 Physician United States
Primary
Concomitant
Granulocytopenia Other Serious 1/13/2010 54 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 1/19/2010 54 Male 231 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 2/21/2010 58 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Death Death 2/8/2010 49 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 4/6/2010 47 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 4/15/2010 31 Male 226 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 4/5/2010 34 Male 6/24/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 36 Male 6/30/2010 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 7/1/2010 58 Female 9/8/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/16/2010 61 Female 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue 10/5/2010 58 Female 11/10/2010 Consumer
Primary
Concomitant
Suicide Attempt Other Serious 60 Female 11/11/2010 Germany
Primary
Secondary
Hypertension Other Serious 4/17/2010 57 Male 240 lb 11/29/2010 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 11/24/2010 25 Female 170 lb 12/10/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/1/2010 63 Female 1/4/2011 Other Health Professional United States
Primary
Secondary
Medication Error Death 82 Female 1/21/2011 Physician United States
Primary
Secondary
Hydronephrosis Other Serious 10/29/2010 59 Female 1/26/2011 Physician United States
Primary
Secondary
Catatonia Hospitalization 26 Male 1/31/2011 Physician Netherlands
Primary
Secondary
Dysarthria Hospitalization 12/28/2010 51 Male 204 lb 2/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteopenia Other Serious 53 Female 2/17/2011 Other Health Professional Brazil
Primary
Secondary
Dysarthria Hospitalization 12/28/2010 51 Male 204 lb 2/22/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/1/2010 63 Female 2/24/2011 Physician United States
Primary
Secondary
Concomitant
Medication Error Death 82 Female 3/6/2011 Other Health Professional United States
Primary
Secondary
Medication Error Death 82 Female 3/7/2011 Physician United States
Primary
Secondary
Myocarditis Hospitalization 1/18/2011 25 Male 206 lb 3/17/2011 Pharmacist United States
Primary
Concomitant
Malaise Other Serious Male 4/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 2/16/2011 45 Female 4/12/2011 Pharmacist United States
Primary
Secondary
Concomitant
Dyskinesia Other Serious Female 136 lb 2/28/2011 Lawyer United States
Primary
Concomitant
Muscle Spasms Other Serious 5/19/2010 60 Male 160 lb 6/1/2011 Consumer United States
Primary
Concomitant
Convulsion Life Threatening Female 6/13/2011 Pharmacist United Kingdom
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/1/2006 30 Male 6/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Antipsychotic Drug Level Increased Other Serious 7/1/2005 36 Male 6/11/2011 Consumer United Kingdom
Primary
Secondary
Laryngeal Cancer Life Threatening 2/1/2008 51 Male 6/12/2011 Other Health Professional United States
Primary
Concomitant
Hyperthyroidism Other Serious Male 6/14/2011 Consumer United Kingdom
Primary
Concomitant
Hyperthyroidism Other Serious Female 6/14/2011 Consumer United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 9/15/2003 43 Male 6/14/2011 Consumer United Kingdom
Primary
Concomitant
Hepatitis C Virus Test Positive Death Male 6/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Full Blood Count Decreased Hospitalization 1/6/2004 50 Male 6/14/2011 Other Health Professional Ireland
Primary
Concomitant
Renal Cancer Death Male 6/15/2011 Pharmacist United Kingdom
Primary
Concomitant
Body Mass Index Increased Hospitalization 4/12/2011 45 Male 6/16/2011 Physician Australia
Primary
Concomitant
Hallucination, Visual Other Serious 2/23/2011 63 Female 6/16/2011 Physician Canada
Primary
Concomitant
Granulocytopenia Other Serious 4/6/2010 47 Female 6/22/2011 Physician United States
Primary
Concomitant
Respiratory Failure Death 6/9/2010 43 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 24 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 6/17/2010 36 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 6/28/2010 29 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Cardiac Failure Death 7/1/2010 66 Female 6/22/2011 Physician United States
Primary
Concomitant
Leukopenia Other Serious 7/22/2010 56 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 8/2/2010 44 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Colon Operation Hospitalization 49 Male 6/22/2011 Physician United States
Primary
Concomitant
Granulocytopenia Other Serious 8/4/2010 59 Female 124 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Agranulocytosis Other Serious 8/9/2010 33 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 9/1/2010 19 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 9/7/2010 44 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 9/16/2010 40 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 10/7/2010 31 Male 6/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 58 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 11/8/2010 61 Male 180 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 12/1/2010 41 Male 190 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 12/8/2010 56 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 1/3/2011 18 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia 53 Female 235 lb 6/22/2011 Physician United States
Primary
Concomitant
Leukopenia Other Serious 2/15/2011 50 Male 138 lb 6/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/28/2011 59 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Acute Respiratory Failure Death 2/26/2011 57 Male 6/22/2011 Other Health Professional United States
Primary
Concomitant
Granulocytopenia Other Serious 3/14/2011 14 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Life Threatening 3/10/2011 53 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Multiple Drug Overdose Death 2/9/2011 22 Female 6/22/2011 Physician United States
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 3/24/2011 27 Male 147 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 4/12/2011 58 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 1/6/2011 43 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 5/25/2011 49 Male 6/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 5/5/2011 39 Male 6/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data