Clozapine combined with Lisinopril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Required Intervention 35 Female 174 lb 12/28/2005 Consumer United States
Primary
Concomitant
Menorrhagia Hospitalization 10/2/2005 47 Female 2/15/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/23/2005 50 Male 201 lb 12/14/2005 Other Health Professional United States
Primary
Concomitant
Pre-existing Disease Hospitalization 11/30/2004 82 Female 138 lb 1/18/2005 Other Health Professional United States
Primary
Concomitant
Posturing Life Threatening 3/21/2006 Male 5/17/2006 Pharmacist United States
Primary
Concomitant
Death Death 5/14/2006 57 Female 5/22/2006 United States
Primary
Concomitant
Death Death 5/14/2006 57 Female 6/21/2006 United States
Primary
Concomitant
Cardiac Death Death 5/27/2006 62 Male 6/21/2006 United States
Primary
Concomitant
Cardiac Disorder Death 5/27/2006 62 Male 7/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/9/2006 48 Male 207 lb 5/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/3/2006 60 Male 3/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/23/2005 69 Male 4/4/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/13/2005 33 Male 5/15/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/13/2005 37 Female 209 lb 2/28/2006 United States
Primary
Concomitant
Leukopenia Life Threatening 10/17/2005 59 Female 2/3/2006 United States
Primary
Concomitant
Granulocytopenia Life Threatening 10/5/2005 51 Female 1/25/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/17/2005 20 Female 1/27/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/27/2005 44 Male 1/18/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/14/2005 40 Female 2/15/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/13/2005 64 Male 1/30/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/11/2005 46 Female 2/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/7/2005 47 Male 1/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/10/2005 48 Male 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/31/2005 33 Male 2/9/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 10/31/2005 48 Female 3/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/7/2006 81 Female 5/23/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 4/10/2006 64 Female 5/22/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/2/2005 56 Male 244 lb 1/11/2006 Consumer United States
Primary
Concomitant
Neoplasm Malignant Death 7/4/2006 78 Male 7/24/2006 United States
Primary
Concomitant
Granulocytopenia 1/3/2006 60 Male 5/9/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/28/2005 39 Male 6/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/31/2005 43 Male 1/6/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/23/2005 55 Male 2/27/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 2/10/2006 54 Female 6/1/2006 United States
Primary
Concomitant
Hypoglycaemic Coma Death 6/12/2006 49 Male 8/24/2006 United States
Primary
Concomitant
Psychotic Disorder Required Intervention 35 Male 11/7/2006 United States
Primary
Concomitant
Sudden Death Hospitalization 12/31/2006 74 Female 2/12/2007 Physician United States
Primary
Concomitant
Mitral Valve Incompetence Hospitalization 2/1/2007 Male 124 lb 2/16/2007 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 11/24/2006 54 Male 2/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/1/2007 47 Male 154 lb 4/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Hospitalization 12/31/2006 74 Female 4/2/2007 Physician United States
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 45 Male 4/18/2007 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 2/1/2007 47 Male 154 lb 4/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Shock Required Intervention 2/15/2007 48 Male 5/16/2007 United States
Primary
Secondary
Concomitant
Eosinophilia Hospitalization 12/22/2006 55 Female 6/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2007 53 Male 7/5/2007 Physician United States
Primary
Concomitant
Hypertension Death 11/6/2007 Male 280 lb 12/1/2007 Consumer United States
Primary
Secondary
Concomitant
Hypertensive Heart Disease Death 11/6/2007 Male 280 lb 12/1/2007 Consumer United States
Primary
Secondary
Concomitant
Hypertension Death 11/6/2007 Male 280 lb 12/1/2007 Consumer United States
Primary
Secondary
Concomitant
Retinal Exudates Other Serious 6/9/2008 42 Female 8/18/2008 Other Health Professional United States
Primary
Concomitant
Telangiectasia Other Serious 6/9/2008 42 Female 8/27/2008 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2008 42 Female 8/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Demyelination Hospitalization 5/8/2008 Male 165 lb 12/1/2008 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2008 42 Female 11/19/2008 Physician United States
Primary
Secondary
Concomitant
Retinal Exudates Other Serious 6/9/2008 42 Female 1/9/2009 Physician United States
Primary
Concomitant
Tongue Disorder Hospitalization 9/18/2008 Male 182 lb 2/12/2009 Physician United States
Primary
Concomitant
Suicidal Ideation Hospitalization 3/14/2002 38 Female 276 lb 4/10/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/1/2005 59 Female 175 lb 6/18/2009 United States
Primary
Concomitant
Renal Failure Other Serious 4/9/2003 52 Male 147 lb 6/19/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious Male 7/1/2009 United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 1/1/2003 29 Male 328 lb 7/9/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 10/20/2000 53 Female 207 lb 7/9/2009 United States
Primary
Concomitant
Pulmonary Embolism Death 4/22/2009 34 Male 271 lb 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/22/2009 34 Male 10/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Death 4/22/2009 34 Male 271 lb 11/2/2009
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/10/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Demyelination Hospitalization 5/8/2008 Male 165 lb 11/19/2009 Physician
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/30/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/18/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/28/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 47 Male 257 lb 1/13/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/4/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Haematemesis Other Serious 11/18/2009 Female 1/28/2010 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 8/12/2009 Female 129 lb Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/18/2010 79 Male 3/3/2010 Physician
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/18/2010 79 Male 3/15/2010 Physician United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/15/2010 79 Male 3/19/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 6/20/2008 48 Female 4/22/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/18/2010 79 Male 4/19/2010 Physician
Primary
Concomitant
Granulocytopenia Hospitalization 5/13/2010 35 Male 6/3/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Life Threatening 5/13/2010 35 Male 157 lb 6/18/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 16 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 31 Male 173 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Carotid Arteriosclerosis Death 61 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 22 Male 450 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 43 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 54 Male 150 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 30 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Death 65 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 11/27/2009 58 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 58 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 1/4/2010 60 Female 6/24/2010 Physician United States
Primary
Concomitant
Death Death 1/26/2010 65 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 50 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Death 4/1/2010 48 Male 323 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Granulocytopenia Other Serious 10/23/2009 51 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/1/2005 59 Female 178 lb 7/14/2010 United States
Primary
Concomitant
Fracture Displacement Hospitalization 8/1/2010 52 Male 262 lb 9/24/2010 Other Health Professional United States
Primary
Concomitant
Pathological Fracture Hospitalization 8/1/2010 52 Male 262 lb 11/11/2010 Physician United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 12/1/2009 12/14/2010 Physician United States
Primary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 6/20/2008 48 Female 12/29/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Death 2/20/2011 44 Male 242 lb 3/11/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hydrocephalus Other Serious 1/1/2010 47 Male 240 lb 3/18/2011 Consumer United States
Primary
Secondary
Concomitant
Enterocolitis Infectious Hospitalization 2/9/2011 61 Male 4/7/2011 Other Health Professional United States
Primary
Concomitant
Haemoptysis Death 3/26/2004 73 Male 6/4/2011 Pharmacist United States
Primary
Concomitant
Abscess Hospitalization 6/27/2007 49 Female 6/5/2011 Physician United Kingdom
Primary
Concomitant
Granulocytopenia Other Serious 4/13/2010 30 Male 182 lb 6/22/2011 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/27/2010 59 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 5/5/2010 79 Male 6/22/2011 Physician United States
Primary
Concomitant
Leukopenia Other Serious 6/3/2010 72 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Death 82 Female 210 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 6/22/2010 54 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 7/1/2010 55 Male 330 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Cardiac Failure Death 7/1/2010 66 Female 6/22/2011 Physician United States
Primary
Concomitant
Leukopenia Other Serious 9/13/2010 46 Male 6/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 47 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 12/8/2010 56 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 11/26/2010 67 Female 150 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 1/4/2011 22 Male 230 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 2/13/2011 36 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 11/22/2010 63 Male 228 lb 6/22/2011 Other Health Professional United States
Primary
Concomitant
Granulocytopenia Other Serious 11/24/2010 71 Female 164 lb 6/22/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 4/12/2011 58 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Intestinal Obstruction Death 55 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 10/21/2010 37 Female 6/22/2011 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization Female 280 lb 7/8/2011 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 4/17/2011 61 Male 7/25/2011 Physician United Kingdom
Primary
Concomitant
Paranoia Other Serious Female 8/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Anxiety Other Serious 1/4/2011 60 Male 199 lb 9/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Coma Scale Abnormal Hospitalization 2/17/2009 39 Male 9/2/2011 Germany
Primary
Secondary
Concomitant
Overdose Hospitalization 2/17/2009 39 Male 9/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Agitation Hospitalization 2/17/2009 39 Male 9/2/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 7/1/2010 72 Female 111 lb 8/31/2011 Lawyer United States
Primary
Concomitant
Intentional Overdose Other Serious 8/4/2011 21 Female 9/12/2011 Consumer United States
Primary
Concomitant
Overdose Other Serious 2/17/2009 39 Male 9/13/2011 Physician Germany
Primary
Secondary
Cardiac Arrest Other Serious Male 1/4/2012 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/2/2011 45 Male 2/1/2012 Physician United States
Primary
Secondary
Concomitant
Fall Hospitalization 12/13/2011 Male 2/3/2012 Physician Austria
Primary
Secondary
Concomitant
Megacolon Hospitalization 12/13/2011 Male 2/9/2012 Physician Austria
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 12/9/2011 50 Male 2/10/2012 Physician Austria
Primary
Secondary
Concomitant
Blood Glucose Decreased Hospitalization 5/1/2010 60 Male 6/4/2012 Consumer United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 7/7/2011 54 Male 6/28/2012 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 6/13/2011 30 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Death Death 4/26/2011 56 Female 6/28/2012 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 7/26/2011 57 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 9/15/2011 33 Male 148 lb 6/28/2012 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 10/4/2011 49 Male 160 lb 6/28/2012 Pharmacist United States
Primary
Concomitant
Death Death Male 6/28/2012 Pharmacist United States
Primary
Concomitant

Drug Data