Clozapine combined with Levothyroxine Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 12/19/2005 65 Female 12/29/2005 United States
Primary
Concomitant
Staphylococcal Infection Death 11/28/2005 44 Male 1/10/2006 Pharmacist United States
Primary
Concomitant
Aneurysm Death 43 Male 1/11/2006 United States
Primary
Concomitant
Cardiomegaly Death Female 1/16/2006 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukopenia Required Intervention 42 Male 2/8/2006 United States
Primary
Concomitant
Staphylococcal Infection Death 11/28/2005 44 Male 352 lb 2/9/2006 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/14/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash 6/3/2005 55 Female 165 lb 2/28/2006 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Male 3/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Unknown 3/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 51 Female 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiomegaly Death 12/1/2005 49 Female 3/7/2006 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/10/2006 United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/22/2005 38 Male 245 lb 4/1/2005 Pharmacist United States
Primary
Concomitant
Lung Neoplasm Malignant Death 1/30/2006 68 Female 3/14/2006 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukopenia Required Intervention 9/28/2005 42 Female 328 lb 12/14/2005 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Unevaluable Event Death 8/7/2005 54 Female 170 lb 12/14/2005 Other Health Professional United States
Primary
Concomitant
Intentional Drug Misuse Death 5/16/2005 49 Female 12/14/2005 Physician United States
Primary
Concomitant
Neutropenia Other Serious 11/15/2004 27 Female 12/14/2004 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Other Serious 51 Female 3/27/2006 United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 51 Female 3/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 4/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 4/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 1/30/2006 68 Female 4/7/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 8/22/2005 42 Male 4/7/2006 United States
Primary
Concomitant
Death Death 3/1/2006 51 Female 4/12/2006 United States
Primary
Concomitant
Death Death 3/28/2006 51 Female 5/1/2006 United States
Primary
Concomitant
Cardiac Disorder Death 1/1/2006 90 Female 5/22/2006 United States
Primary
Concomitant
Cardiac Death Death 5/27/2006 62 Male 6/21/2006 United States
Primary
Concomitant
Aortic Dissection Death 1/1/2006 90 Female 6/21/2006 United States
Primary
Concomitant
Infection Death 12/19/2005 65 Female 7/10/2006 United States
Primary
Concomitant
Cardiac Disorder Death 5/27/2006 62 Male 7/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/7/2005 55 Female 5/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/1/2005 61 Male 173 lb 5/12/2006 Consumer United States
Primary
Concomitant
Malaise Required Intervention 9/10/2005 50 Male 1/18/2006 United States
Primary
Concomitant
Leukopenia Life Threatening 10/5/2005 72 Male 263 lb 4/26/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/4/2005 17 Male 6/20/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 9/6/2005 46 Male 5/24/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/3/2005 42 Male 1/25/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/12/2005 44 Female 1/30/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/11/2005 46 Female 2/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/6/2005 17 Male 2/6/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 10/31/2005 48 Female 3/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/8/2005 59 Female 3/22/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/11/2006 56 Female 5/23/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 4/4/2006 44 Female 5/23/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/13/2006 40 Female 160 lb 5/23/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/10/2006 43 Male 6/14/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 4/10/2006 64 Female 5/22/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/25/2005 53 Female 1/31/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/28/2005 25 Male 3/22/2006 Consumer United States
Primary
Concomitant
Vomiting Required Intervention 10/31/2005 74 Female 2/8/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/31/2005 40 Male 2/6/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/9/2005 46 Male 1/13/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/13/2005 46 Male 5/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/2/2005 24 Female 1/24/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/22/2006 46 Female 5/8/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/1/2005 34 Female 140 lb 4/17/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 1/31/2006 36 Male 4/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/13/2006 48 Female 203 lb 5/18/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/31/2005 28 Female 2/15/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 11/10/2005 50 Female 3/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/8/2006 61 Female 4/10/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/3/2006 46 Male 5/9/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/8/2006 31 Male 220 lb 4/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/21/2006 50 Male 5/17/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 3/7/2006 38 Male 158 lb 6/1/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 3/22/2006 32 Male 6/12/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/6/2005 43 Male 1/6/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/6/2005 19 Female 6/16/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 9/27/2005 42 Female 328 lb 2/3/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 2/10/2006 54 Female 6/1/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/6/2005 57 Female 1/9/2006 Consumer United States
Primary
Concomitant
Tardive Dyskinesia Other Serious Female 8/29/2006 United States
Primary
Secondary
Respiratory Rate Increased Other Serious 54 Female 8/29/2006 United Kingdom
Primary
Secondary
Concomitant
Small Cell Carcinoma Death 7/26/2006 45 Female 8/31/2006 United States
Primary
Concomitant
Pharmaceutical Product Complaint 7/18/2006 45 Female 9/20/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 7/27/2006 43 Female 9/28/2006 United States
Primary
Concomitant
Therapy Non-responder Other Serious 50 Female 9/27/2006 Physician India
Primary
Secondary
Death Death 9/7/2006 65 Female 10/2/2006 United States
Primary
Concomitant
Self-injurious Ideation 7/18/2006 45 Female 194 lb 10/10/2006 Other Health Professional United States
Primary
Concomitant
Granulocytopenia Required Intervention 7/27/2006 43 Female 10/10/2006 Other Health Professional United States
Primary
Concomitant
Death Death 8/26/2006 74 Male 127 lb 11/3/2006 United States
Primary
Concomitant
Death Death 9/1/2006 50 Male 11/6/2006 Other Health Professional United States
Primary
Concomitant
Psychotic Disorder Required Intervention 35 Male 11/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/23/2005 46 Male 206 lb 2/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/27/2006 Male 184 lb 1/29/2007 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/28/2006 44 Male 2/21/2007 United States
Primary
Secondary
Concomitant
Sudden Death Hospitalization 12/31/2006 74 Female 2/12/2007 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 11/20/2006 44 Female 238 lb 3/8/2007 Physician Germany
Primary
Concomitant
Speech Disorder Other Serious 1/1/2006 64 Female 3/9/2007 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 60 Female 3/14/2007 Other Health Professional New Zealand
Primary
Concomitant
Polyserositis Other Serious 11/1/2005 60 Female 3/19/2007 Physician New Zealand
Primary
Concomitant
Tardive Dyskinesia Other Serious 50 Female 12/19/2006 United States
Primary
Secondary
Sedation Hospitalization 60 Female 3/28/2007 Physician New Zealand
Primary
Concomitant
Sudden Death Hospitalization 12/31/2006 74 Female 4/2/2007 Physician United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 8/15/2005 23 Male 218 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 7/1/2005 23 Male 218 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 8/31/2006 Female 7/4/2007 Physician Germany
Primary
Concomitant
Psychotic Disorder Death 6/1/2007 Male 195 lb 10/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/12/2008 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/13/2008 Physician United States
Primary
Concomitant
Sepsis Death 9/20/2007 72 Female 2/13/2008 Germany
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 2/6/2008 Male 2/19/2008 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/5/2008 Female 2/22/2008 Physician Norway
Primary
Concomitant
Leukopenia Other Serious 3/17/2008 65 Male 164 lb 5/27/2008 Physician United States
Primary
Secondary
Concomitant
Metastases To Breast Other Serious 3/1/2008 Female 6/19/2008 Other Health Professional United States
Primary
Concomitant
Tachycardia Death 7/10/2007 Female 256 lb 6/20/2008 Germany
Primary
Concomitant
Overdose Death 4/14/2006 34 Female 6/18/2008 United Kingdom
Primary
Secondary
Multiple Drug Overdose Death 4/14/2006 34 Female 6/23/2008 United Kingdom
Primary
Secondary
Eosinophilia Hospitalization 4/3/2008 36 Male 6/26/2008 Consumer France
Primary
Secondary
Metastases To Breast Other Serious 3/1/2008 Female 6/27/2008 Other Health Professional United States
Primary
Concomitant
Overdose Death 4/14/2006 34 Female 6/27/2008 Other Health Professional Japan
Primary
Secondary
Renal Failure Acute Hospitalization 2/27/2008 Male 7/2/2008 United States
Primary
Secondary
Concomitant
Overdose Death 4/14/2006 34 Female 6/23/2008 United Kingdom
Primary
Secondary
White Blood Cell Disorder Other Serious 7/6/2008 Female 7/16/2008 Other Health Professional Argentina
Primary
Concomitant
White Blood Cell Disorder Other Serious 7/6/2008 Female 7/22/2008 Other Health Professional Argentina
Primary
Concomitant
Respiratory Depression Death 4/14/2006 34 Female 7/14/2008 United Kingdom
Primary
Secondary
Respiratory Depression Death 34 Female 7/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Depression Death 4/14/2006 34 Female 7/17/2008 United Kingdom
Primary
Secondary
Respiratory Depression Death 4/14/2006 34 Female 7/25/2008 Other Health Professional Japan
Primary
Secondary
Breast Cancer Metastatic Other Serious 3/1/2008 56 Female 7/14/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Depression Death 4/14/2006 34 Female 7/21/2008 United Kingdom
Primary
Secondary
Tachycardia Death 7/10/2007 Female 256 lb 7/29/2008 Germany
Primary
Secondary
Concomitant
Respiratory Depression Death 4/14/2006 34 Female 7/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Depression Death 8/14/2006 34 Female 7/22/2008 United Kingdom
Primary
Secondary
Respiratory Depression Death 4/14/2006 34 Female 7/21/2008 United Kingdom
Primary
Secondary
White Blood Cell Disorder Other Serious 7/6/2008 Female 8/5/2008 Other Health Professional Argentina
Primary
Concomitant
White Blood Cell Count Decreased 9/22/2008 34 Female 9/22/2008 Pharmacist United States
Primary
Concomitant
Tonsillitis Hospitalization 3/28/2008 36 Male 11/4/2008 France
Primary
Secondary
Tonsillitis Hospitalization 3/28/2008 36 Male 11/12/2008 France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/3/2008 49 Male 212 lb 12/19/2008 Pharmacist United States
Primary
Concomitant
Troponin I Increased Hospitalization 1/30/2008 Female 213 lb 1/9/2009 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 Female 213 lb 3/9/2009 Physician United States
Primary
Concomitant
Retinopathy Other Serious 55 Female 3/5/2009 Physician Australia
Primary
Concomitant
Retinal Pigmentation Disability 55 Female 3/16/2009 Physician Australia
Primary
Concomitant
Tachycardia Other Serious 2/1/2008 Female 6/1/2009 Physician Norway
Primary
Concomitant

Drug Data