Clozapine combined with Lansoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Aneurysm Death 43 Male 1/11/2006 United States
Primary
Concomitant
Respiratory Disorder Death 12/26/2005 63 Male 1/16/2006 United States
Primary
Concomitant
Cardiac Arrest Death 1/3/2006 64 Female 1/19/2006 United States
Primary
Concomitant
Sepsis Death 8/2/2005 65 Male 165 lb 2/8/2006 United States
Primary
Concomitant
Respiratory Disorder Death 12/26/2005 63 Male 2/16/2006 United States
Primary
Concomitant
Menorrhagia Hospitalization 10/2/2005 47 Female 2/15/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2006 45 Female 170 lb 3/7/2006 Other Health Professional United States
Primary
Concomitant
Death Death 3/6/2006 54 Female 3/27/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/25/2006 34 Male 5/25/2006 United Kingdom
Primary
Concomitant
Death Death 1/1/2006 55 Female 6/14/2006 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Death 5/30/2006 55 Female 7/6/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/18/2006 46 Female 3/22/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/23/2006 23 Male 180 lb 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/3/2006 20 Female 179 lb 3/28/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/7/2005 28 Female 5/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/27/2005 33 Male 3/7/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 10/27/2005 47 Female 1/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/15/2006 43 Female 202 lb 4/17/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 9/12/2005 60 Male 156 lb 1/9/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/28/2005 39 Male 6/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/9/2006 22 Male 5/9/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/8/2006 24 Male 5/9/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 11/28/2005 53 Male 5/15/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/1/2005 34 Male 2/24/2006 Consumer United States
Primary
Concomitant
Pneumonia Aspiration Death 9/19/2006 90 Male 10/11/2006 United States
Primary
Concomitant
Neutrophil Count Decreased Death 10/5/2006 76 Male 10/16/2006 United States
Primary
Concomitant
Neutrophil Count Decreased Death 10/5/2006 76 Male 11/20/2006 Consumer United States
Primary
Concomitant
Head Injury Other Serious 12/6/2006 38 Male 157 lb 12/27/2006 Physician United Kingdom
Primary
Concomitant
Head Injury Other Serious 12/6/2006 38 Male 157 lb 12/22/2006 Physician United Kingdom
Primary
Concomitant
Leukopenia Other Serious 7/27/2005 50 Female 160 lb 10/23/2006 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Death 34 Male 10/29/2007 Physician United Kingdom
Primary
Concomitant
Septic Shock Death 1/1/2001 Male 11/7/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 7/24/2007 49 Male 165 lb 4/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Death 4/14/2006 34 Female 6/18/2008 United Kingdom
Primary
Secondary
Multiple Drug Overdose Death 4/14/2006 34 Female 6/23/2008 United Kingdom
Primary
Secondary
Overdose Death 4/14/2006 34 Female 6/27/2008 Other Health Professional Japan
Primary
Secondary
Overdose Death 4/14/2006 34 Female 6/23/2008 United Kingdom
Primary
Secondary
Respiratory Depression Death 4/14/2006 34 Female 7/14/2008 United Kingdom
Primary
Secondary
Respiratory Depression Death 34 Female 7/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Depression Death 4/14/2006 34 Female 7/17/2008 United Kingdom
Primary
Secondary
Respiratory Depression Death 4/14/2006 34 Female 7/25/2008 Other Health Professional Japan
Primary
Secondary
Respiratory Depression Death 4/14/2006 34 Female 7/21/2008 United Kingdom
Primary
Secondary
Respiratory Depression Death 4/14/2006 34 Female 7/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Depression Death 8/14/2006 34 Female 7/22/2008 United Kingdom
Primary
Secondary
Respiratory Depression Death 4/14/2006 34 Female 7/21/2008 United Kingdom
Primary
Secondary
White Blood Cell Count Increased Hospitalization 6/4/2008 21 Male 8/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death 5/28/2008 Female 10/9/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 6/24/2008 31 Male 12/1/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/24/2008 31 Male 12/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 6/24/2008 31 Male 12/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 7/12/2008 31 Male 12/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 31 Male 12/22/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 1/1/2008 66 Female 2/19/2009 Physician Switzerland
Primary
Concomitant
Interacting
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 6/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Mesenteric Artery Thrombosis Death 6/20/2009 Female 7/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Blood Creatinine Increased Hospitalization 25 Male 176 lb 9/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lethargy Required Intervention 7/21/2009 88 Female 145 lb 7/22/2009 United States
Primary
Concomitant
Septic Shock Death 1/1/2001 Male 11/30/2009 Physician United Kingdom
Primary
Concomitant
Mesenteric Artery Thrombosis Death 6/20/2009 Female 12/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2002 31 Male 4/1/2010 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 10/21/2009 55 Female 4/22/2010 Other Health Professional France
Primary
Secondary
Concomitant
Repetitive Speech Other Serious 20 Female 203 lb 4/21/2010 Other Health Professional
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 5/10/2010 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 11/10/2009 42 Male 5/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/1/2002 31 Male 5/17/2010 Physician United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 3/1/2002 31 Male 6/4/2010 Physician United Kingdom
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 2/1/2005 37 Male 8/9/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2002 31 Male 8/26/2010 Physician United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 3/1/2002 31 Male 10/6/2010 Physician United Kingdom
Primary
Secondary
Transient Ischaemic Attack Other Serious 9/25/2010 67 Female 185 lb 11/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious Female 11/18/2010 Pharmacist United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 2/1/2005 37 Male 12/2/2010 Other Health Professional United States
Primary
Secondary
Urinary Tract Infection Other Serious Female 12/7/2010 Pharmacist United Kingdom
Primary
Concomitant
Sinobronchitis Other Serious 2/1/2005 37 Male 2/15/2011 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Other Serious 3/1/2002 31 Male 6/2/2011 Physician United Kingdom
Primary
Secondary
Feeling Cold Death Male 154 lb 6/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Gastritis Hospitalization 2/28/2011 56 Male 165 lb 6/6/2011 Other Health Professional Ireland
Primary
Concomitant
Anaemia Other Serious 1/10/2011 59 Male 6/6/2011 Physician United Kingdom
Primary
Concomitant
Anaemia Other Serious 6/1/2005 68 Male 6/3/2011 Consumer United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious Male 6/8/2011 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 10/1/2005 68 Male 6/2/2011 Physician United Kingdom
Primary
Concomitant
Circulatory Collapse Death 2/20/2006 56 Male 6/3/2011 Consumer United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 2/1/2006 43 Male 6/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Laryngeal Cancer Other Serious Female 6/3/2011 Physician United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization Male 6/4/2011 Physician United Kingdom
Primary
Concomitant
Epididymitis Other Serious 6/24/2008 31 Male 6/8/2011 Physician United Kingdom
Primary
Concomitant
Influenza Like Illness Other Serious 11/22/2008 25 Male 6/5/2011 Physician Ireland
Primary
Concomitant
Pulmonary Embolism Death Female 295 lb 6/8/2011 Australia
Primary
Concomitant
Decreased Appetite Other Serious Female 6/4/2011 Physician United Kingdom
Primary
Concomitant
Death Death 5/3/2007 66 Male 6/5/2011 Pharmacist Ireland
Primary
Concomitant
Hepatitis C Virus Test Positive Other Serious 3/1/2002 31 Male 6/9/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatitis C Other Serious 1/1/2009 42 Male 6/9/2011 Physician United Kingdom
Primary
Concomitant
Cardiac Disorder Death Male 6/10/2011 Consumer United Kingdom
Primary
Concomitant
Convulsion Life Threatening Female 6/13/2011 Pharmacist United Kingdom
Primary
Concomitant
Ill-defined Disorder Death Female 6/13/2011 Consumer United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 9/17/2005 69 Male 6/11/2011 Other Health Professional Ireland
Primary
Concomitant
General Physical Health Deterioration Hospitalization 2/1/2005 58 Male 6/11/2011 Physician United Kingdom
Primary
Concomitant
Full Blood Count Increased Hospitalization 9/1/2003 4 Male 6/14/2011 United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Life Threatening 7/12/2004 39 Female 6/14/2011 Consumer United Kingdom
Primary
Concomitant
Confusional State Hospitalization 1/27/2006 76 Male 6/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 5/14/2004 42 Male 163 lb 6/14/2011 Pharmacist United Kingdom
Primary
Concomitant
Electrocardiogram Abnormal Hospitalization 5/10/2006 39 Female 190 lb 6/14/2011 Consumer United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 3/1/2003 25 Male 6/15/2011 Physician United Kingdom
Primary
Concomitant
Overdose Death Female 6/15/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization Male 6/15/2011 United Kingdom
Primary
Concomitant
Accidental Overdose Hospitalization 1/27/2006 76 Male 6/20/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Anaemia Other Serious 2/22/2011 62 Female 6/21/2011 Physician United Kingdom
Primary
Concomitant
Hepatitis C Virus Test Positive Other Serious 3/1/2002 31 Male 6/22/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 5/6/2011 63 Female 6/22/2011 Physician United Kingdom
Primary
Concomitant
Medication Error Hospitalization 1/27/2006 76 Male 6/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Flushing Other Serious 5/22/2011 74 Female 6/24/2011 Physician United Kingdom
Primary
Concomitant
Medication Error Other Serious 1/24/2011 26 Female 6/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hyperlipidaemia Death Male 6/27/2011 Other Health Professional Ireland
Primary
Concomitant
Cirrhosis Alcoholic Other Serious 3/1/2002 31 Male 6/28/2011 Physician United Kingdom
Primary
Secondary
Neutropenia Other Serious 1/1/2011 47 Male 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 1/1/2002 26 Male 6/29/2011 Physician United Kingdom
Primary
Concomitant
Differential White Blood Cell Count Abnormal Hospitalization 3/23/2011 49 Female 6/29/2011 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Mellitus Life Threatening Female 6/29/2011 Pharmacist United Kingdom
Primary
Concomitant
Medication Error Hospitalization 1/27/2006 76 Male 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Confusional State Hospitalization 1/27/2006 76 Male 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 4/26/2011 49 Female 7/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2002 31 Male 7/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cirrhosis Alcoholic Other Serious 3/1/2002 31 Male 7/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Coagulation Test Abnormal Hospitalization 5/23/2011 39 Male 154 lb 7/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 5/6/2011 63 Female 7/5/2011 Physician United Kingdom
Primary
Concomitant
Differential White Blood Cell Count Abnormal 3/23/2011 49 Female 7/14/2011 Physician United Kingdom
Primary
Concomitant
Death Death 3/7/2011 79 Female 7/14/2011 United Kingdom
Primary
Concomitant
Accidental Overdose Hospitalization 1/27/2006 76 Male 7/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sickle Cell Trait Other Serious 5/3/2011 36 Male 7/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Disability 2/10/2011 62 Female 148 lb 7/22/2011 Physician United Kingdom
Primary
Concomitant
Neutropenia Other Serious 1/1/2011 47 Male 7/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Conduction Disorder Hospitalization 1/1/2002 26 Male 7/25/2011 Physician United Kingdom
Primary
Concomitant
Cardiac Arrest Death 1/18/2011 46 Male 7/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Hospitalization 4/26/2011 49 Female 7/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 6/25/2011 61 Male 7/27/2011 Physician Italy
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/1/2011 47 Male 8/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization Male 8/3/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Sickle Cell Trait Other Serious 5/3/2011 36 Male 8/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 6/25/2011 61 Male 8/3/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2011 47 Male 8/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lymphocyte Count Increased Other Serious 7/6/2010 49 Female 8/9/2011 Physician United Kingdom
Primary
Concomitant
Spinal Fracture Other Serious 2/10/2011 62 Female 148 lb 8/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Accidental Overdose Hospitalization 1/27/2006 76 Male 6/20/2011 Physician United Kingdom
Primary
Secondary
Concomitant
C-reactive Protein Increased Death 1/12/2011 46 Male 8/19/2011 Physician United Kingdom
Primary
Concomitant
Hypotension Other Serious Male 8/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 7/14/2011 51 Male 8/29/2011 Pharmacist United States
Primary
Concomitant
Hepatitis C Virus Test Positive Other Serious Male 9/2/2011 Physician United Kingdom
Primary
Concomitant
Cough Other Serious 12/22/2010 62 Male 9/6/2011 Physician Ireland
Primary
Concomitant
Circulatory Collapse Other Serious 11/14/2010 59 Female 9/7/2011 Other Health Professional Ireland
Primary
Concomitant
Death Other Serious Male 9/9/2011 Physician Ireland
Primary
Concomitant

Drug Data