Clozapine combined with Haloperidol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Aneurysm Death 43 Male 1/11/2006 United States
Primary
Concomitant
Respiratory Disorder Death 12/26/2005 63 Male 1/16/2006 United States
Primary
Concomitant
Thinking Abnormal Other Serious 1/1/2002 60 Female 2/6/2006 Physician Switzerland
Primary
Concomitant
Respiratory Disorder Death 12/26/2005 63 Male 2/16/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/31/2006 48 Female 2/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/27/2006 50 Male 3/9/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 2/24/2006 55 Female 3/14/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2005 39 Male 3/24/2006 Pharmacist United Kingdom
Primary
Concomitant
Sudden Death Death 2/28/2006 72 Male 3/22/2006 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 8/16/2005 57 Female 180 lb 12/14/2005 Physician United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 2/8/2005 15 Male 3/7/2005 Pharmacist United States
Primary
Secondary
Neutropenia Other Serious 11/15/2004 27 Female 12/14/2004 Pharmacist United States
Primary
Concomitant
Convulsion Other Serious 8/27/2005 35 Female 210 lb 12/14/2005 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 2/3/2006 43 Female 183 lb 4/3/2006 United States
Primary
Concomitant
Loss Of Consciousness Life Threatening 8/13/2005 29 Male 213 lb 4/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sudden Death Death 3/1/2006 72 Male 4/7/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2005 39 Male 4/26/2006 Pharmacist United Kingdom
Primary
Concomitant
Posturing Life Threatening 3/21/2006 Male 5/17/2006 Pharmacist United States
Primary
Concomitant
Hypertension Death 4/1/2006 46 Female 5/19/2006 United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 9/21/2005 35 Male 6/12/2006 United Kingdom
Primary
Secondary
Concomitant
Mental Disorder Required Intervention 1/26/2006 45 Female 6/14/2006 United States
Primary
Concomitant
Choking Hospitalization 6/12/2006 35 Female 137 lb 6/29/2006 Physician Malta
Primary
Concomitant
Vomiting Hospitalization 34 Male 7/17/2006 France
Primary
Secondary
Concomitant
Interacting
Rash Macular Other Serious 34 Male 7/21/2006 France
Primary
Concomitant
Granulocytopenia Required Intervention 1/9/2006 48 Male 207 lb 5/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/17/2006 45 Male 5/17/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 1/20/2006 37 Female 4/3/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/23/2006 42 Female 6/12/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/12/2005 35 Male 275 lb 2/28/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/4/2005 40 Male 6/20/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 10/12/2005 43 Female 1/25/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/9/2005 29 Male 155 lb 6/20/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/30/2005 64 Male 177 lb 2/8/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 9/16/2005 21 Female 1/17/2006 Consumer United States
Primary
Concomitant
Leukopenia Life Threatening 10/5/2005 72 Male 263 lb 4/26/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/4/2005 42 Male 5/24/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 8/19/2005 22 Male 1/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/1/2005 26 Female 3/6/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/18/2005 56 Female 5/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/27/2005 33 Male 3/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/17/2005 35 Male 1/30/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/13/2006 50 Female 5/12/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/17/2005 30 Female 153 lb 2/8/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/7/2005 47 Male 1/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/26/2005 16 Male 1/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/14/2005 29 Male 150 lb 3/22/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/1/2005 44 Male 217 lb 5/17/2006 United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 2/14/2005 51 Male 5/23/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/13/2006 31 Male 5/23/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 4/10/2006 64 Female 5/22/2006 Consumer United States
Primary
Concomitant
Tonic Convulsion 29 Male 212 lb 1/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Leukopenia Required Intervention 10/13/2005 50 Male 281 lb 1/23/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/21/2005 52 Female 217 lb 1/23/2006 Consumer United States
Primary
Concomitant
Neoplasm Malignant Death 7/4/2006 78 Male 7/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/13/2006 56 Female 180 lb 5/11/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/8/2006 24 Male 5/9/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/10/2006 52 Female 5/22/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/17/2006 19 Male 4/11/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/16/2006 38 Male 5/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/6/2005 45 Male 5/11/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 2/6/2006 55 Female 4/3/2006 United States
Primary
Concomitant
Social Avoidant Behaviour Other Serious 42 Male 8/24/2006 Physician Germany
Primary
Secondary
Concomitant
Completed Suicide Death 7/3/2006 73 Male 148 lb 8/24/2006 Physician Russian Federation
Primary
Concomitant
Trismus Other Serious 47 Female 9/4/2006 United States
Primary
Concomitant
Stupor Hospitalization 8/10/2006 Male 139 lb 10/20/2006 Physician Switzerland
Primary
Secondary
Concomitant
Restlessness Death 84 Male 11/8/2006 Other Health Professional Netherlands
Primary
Secondary
Tachypnoea Other Serious 73 Male 11/7/2006 Other Health Professional Netherlands
Primary
Secondary
Muscle Contractions Involuntary Death 71 Male 11/7/2006 Other Health Professional Netherlands
Primary
Secondary
Sudden Death Death 7/7/2006 35 Male 269 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
Salivary Hypersecretion Other Serious 48 Male 172 lb 1/15/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Posture Abnormal Other Serious 52 Female 1/19/2007 Other Health Professional Spain
Primary
Secondary
White Blood Cell Count Increased Death 12/1/2006 28 Female 1/16/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Death 12/1/2006 28 Female 1/17/2007 United Kingdom
Primary
Secondary
Vomiting Hospitalization 62 Male 2/22/2007 Other Health Professional Hungary
Primary
Concomitant
Sudden Death Hospitalization 12/31/2006 74 Female 2/12/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 33 Female 168 lb 3/14/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Weight Increased Other Serious 33 Female 168 lb 4/6/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Sudden Death Hospitalization 12/31/2006 74 Female 4/2/2007 Physician United States
Primary
Concomitant
Suicide Attempt Other Serious 60 Female 5/1/2007 Germany
Primary
Secondary
Prescribed Overdose Hospitalization 1/1/2003 38 Male 250 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Drug Toxicity Hospitalization 36 Male 6/12/2007 Physician United States
Primary
Concomitant
Obesity Other Serious 1/1/2004 35 Female 210 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 34 Male 6/22/2007 France
Primary
Secondary
Concomitant
Interacting
Treatment Noncompliance Hospitalization 36 Male 6/21/2007 Physician United States
Primary
Concomitant
Neoplasm Malignant Other Serious 10/1/2005 59 Female 180 lb 7/11/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/2/2007 53 Male 7/5/2007 Physician United States
Primary
Concomitant
Fall Hospitalization 56 Male 9/3/2007 Other Health Professional Greece
Primary
Concomitant
Pyrexia Required Intervention 4/9/2007 44 Male 9/5/2007 Other Health Professional United States
Primary
Concomitant
Fall Hospitalization 74 Male 9/29/2007 Physician Greece
Primary
Concomitant
Syncope Other Serious 56 Female 10/9/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Dry Eye Other Serious 8/1/2003 17 Male 11/2/2007 Physician Switzerland
Primary
Concomitant
Syncope Other Serious 56 Female 11/7/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Septic Shock Death 1/1/2001 Male 11/7/2007 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 62 Male 11/13/2007 Physician Hungary
Primary
Concomitant
Dry Eye Other Serious 8/1/2003 17 Male 11/30/2007 Physician Switzerland
Primary
Concomitant
Urine Osmolarity Decreased Hospitalization 1/11/2007 53 Female 11/27/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Syncope Other Serious 56 Female 152 lb 11/27/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 1/1/2003 31 Male 227 lb 10/9/2007 Lawyer United States
Primary
Concomitant
Dry Eye Other Serious 8/1/2003 17 Male 12/29/2007 Physician Switzerland
Primary
Concomitant
Granulocytopenia Other Serious 2/6/2008 Male 2/19/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2002 48 Male 4/21/2008 Consumer Germany
Primary
Concomitant
Hepatitis Cholestatic Hospitalization 2/5/2008 22 Female 5/1/2008 Other Health Professional France
Primary
Concomitant
Rhabdomyolysis Life Threatening 2/29/2008 41 Male 5/27/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/21/2008 Female 6/30/2008 Physician Philippines
Primary
Concomitant
Pyrexia Life Threatening 2/8/2008 51 Female 8/12/2008 France
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 44 Male 8/21/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Pneumonia Other Serious 41 Male 9/2/2008 Physician United States
Primary
Concomitant
Tardive Dyskinesia Disability 30 Male 9/29/2008 Other Health Professional Germany
Primary
Secondary
Enuresis Hospitalization 10/23/2006 38 Male 10/15/2008 Physician Germany
Primary
Secondary
Concomitant
Hyperventilation Life Threatening 10/23/2006 38 Male 10/21/2008 Physician France
Primary
Secondary
Concomitant
Interacting
Pyrexia Other Serious 1/1/1994 Male 11/6/2008 Physician Australia
Primary
Secondary
Mental Disorder Hospitalization Female 12/3/2008 Germany
Primary
Concomitant
Sedation Hospitalization 1/1/2005 32 Male 12/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Delusion Hospitalization 10/9/2008 49 Male 176 lb 12/11/2008 Physician Germany
Primary
Secondary
Thrombocytopenia Life Threatening 10/21/2008 Female 165 lb 12/12/2008 Pharmacist United States
Primary
Concomitant
Delusion Hospitalization 10/9/2008 49 Male 176 lb 12/17/2008 Physician Germany
Primary
Secondary
Psychotic Disorder Hospitalization 1/1/2005 32 Male 12/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Lower Limb Fracture Other Serious 27 Female 12/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death 43 Male 12/29/2008 Physician United States
Primary
Secondary
Weight Increased Other Serious 28 Female 12/29/2008 Physician Hong Kong
Primary
Secondary
Drug Toxicity Death 1/1/2007 43 Male 12/29/2008 Physician United States
Primary
Secondary
Completed Suicide Death 43 Male 1/13/2009 United States
Primary
Secondary
Completed Suicide Death 43 Male 1/15/2009 Physician United States
Primary
Secondary
Mental Disorder Hospitalization 2/11/2008 48 Female 1/21/2009 Germany
Primary
Secondary
Shock Life Threatening 52 Male 190 lb 1/30/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 37 Male 2/17/2009 Other Health Professional Germany
Primary
Concomitant
Completed Suicide Death 43 Male 2/13/2009 Physician United States
Primary
Secondary
Weight Decreased 6/6/2008 33 Male 212 lb 6/9/2008 Pharmacist United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 35 Female 2/23/2009 Physician United States
Primary
Secondary
Treatment Noncompliance Other Serious 33 Male 2/19/2009 Canada
Primary
Secondary
Concomitant
Restless Legs Syndrome Other Serious 36 Female 3/30/2009 Physician Korea, Republic Of
Primary
Concomitant
Withdrawal Syndrome Hospitalization 45 Female 4/3/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 45 Female 5/14/2009 Other Health Professional Brazil
Primary
Concomitant
Pleural Effusion Hospitalization 64 Female 6/5/2009 United States
Primary
Secondary
Concomitant
Catatonia Other Serious 79 Female 6/5/2009 Other Health Professional United States
Primary
Secondary
Pleural Effusion Hospitalization 64 Female 6/5/2009 United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious Male 6/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Productive Cough Hospitalization 64 Female 6/16/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/1/2005 59 Female 175 lb 6/18/2009 United States
Primary
Concomitant
Vomiting Other Serious Male 6/18/2009 United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 64 Female 7/9/2009 Physician United States
Primary
Secondary
Concomitant
Headache Other Serious 5/1/2009 Male 8/3/2009 Other Health Professional Argentina
Primary
Concomitant
Pulmonary Eosinophilia Hospitalization 64 Female 8/6/2009 Physician Spain
Primary
Concomitant
Urinary Incontinence Other Serious Male 8/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 64 Female 8/20/2009 Physician Spain
Primary
Concomitant
Psychomotor Hyperactivity Other Serious 46 Female 9/15/2009
Primary
Secondary
Concomitant
Wound Infection Other Serious 4/24/2005 9/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Angioedema Life Threatening 8/19/2009 39 Male 178 lb 8/21/2009 Pharmacist United States
Primary
Concomitant
Schizoaffective Disorder Other Serious 29 Male 10/2/2009
Primary
Secondary
Pulmonary Embolism Death 4/22/2009 34 Male 271 lb 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data