Clozapine combined with Furosemide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 1/31/2006 85 Female 2/15/2006 United States
Primary
Concomitant
Respiratory Arrest Life Threatening 1/1/2006 56 Female 2/22/2006 Physician China
Primary
Concomitant
Somnolence Life Threatening 1/1/2006 56 Female 3/3/2006 Physician China
Primary
Concomitant
Renal Failure Death 2/24/2006 55 Female 3/14/2006 United States
Primary
Concomitant
Death Death 4/22/2006 88 Male 5/8/2006 United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/8/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/17/2006 29 Female 157 lb 4/11/2006 United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 1/31/2006 59 Male 4/3/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/1/2005 61 Male 173 lb 5/12/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/26/2005 41 Female 2/6/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 4/10/2006 64 Female 5/22/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/9/2005 46 Male 1/13/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/22/2006 46 Female 5/8/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/22/2006 99 Female 4/20/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 2/6/2006 55 Female 4/3/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/6/2005 57 Female 1/9/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance Death 8/6/2006 81 Female 112 lb 9/11/2006 United States
Primary
Concomitant
Parkinson's Disease Death 7/29/2006 87 Female 136 lb 9/13/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 10/4/2006 United States
Primary
Concomitant
Sudden Death Death 9/25/2006 76 Female 10/10/2006 Other Health Professional United States
Primary
Concomitant
Sudden Death Death 9/25/2006 76 Female 11/2/2006 United States
Primary
Concomitant
Vomiting Hospitalization 62 Male 2/22/2007 Other Health Professional Hungary
Primary
Concomitant
Vomiting Hospitalization 5/12/2006 41 Male 12/19/2006 Other Health Professional United States
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 45 Male 4/18/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 4/23/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/17/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/31/2007 United States
Primary
Concomitant
Drug Effect Decreased Death 6/1/2007 42 Male 279 lb 9/11/2007 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 62 Male 11/13/2007 Physician Hungary
Primary
Concomitant
Renal Failure Other Serious 1/1/1995 Male 11/19/2007 Physician Germany
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/12/2008 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/13/2008 Physician United States
Primary
Concomitant
Obesity Other Serious 6/12/2008 Female 322 lb 8/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Troponin I Increased Hospitalization 1/30/2008 Female 213 lb 1/9/2009 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 Female 213 lb 3/9/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 2/4/2006 59 Male 348 lb 7/31/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 3/25/2003 45 Female 370 lb 8/3/2009 United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 5/29/2007 39 Female 11/9/2009 Physician Germany
Primary
Interacting
Atrial Fibrillation Hospitalization 1/29/2008 Female 213 lb 12/9/2009 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 5/29/2007 39 Female 12/11/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 47 Male 257 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Neutrophilia Other Serious 1/1/2002 58 Male 3/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 77 Female 99 lb 4/6/2010 Consumer Brazil
Primary
Concomitant
Staphylococcal Infection Other Serious 49 Male 290 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 71 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 1/12/2010 70 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Death 4/1/2010 48 Male 323 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Death 1/1/2010 60 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Hypoxic-ischaemic Encephalopathy Other Serious 9/15/2010 55 Female 10/21/2010 Physician United States
Primary
Concomitant
Fatigue 10/5/2010 58 Female 11/10/2010 Consumer
Primary
Concomitant
Urinary Tract Infection Other Serious Female 11/18/2010 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious Female 12/7/2010 Pharmacist United Kingdom
Primary
Concomitant
Pain Other Serious 1/1/2010 53 Female 175 lb 2/11/2011 Consumer United States
Primary
Concomitant
Back Pain Disability 10/1/2009 68 Male 235 lb 3/30/2011 Consumer United States
Primary
Secondary
Concomitant
Abasia Other Serious 10/1/2009 70 Male 235 lb 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Myalgia Other Serious 1/1/2009 69 Male 236 lb 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Nausea Disability 10/1/2009 69 Male 235 lb 4/14/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Irritation Disability 10/1/2009 68 Male 235 lb 4/13/2011 Consumer United States
Primary
Concomitant
Vomiting Disability 10/1/2009 70 Male 235 lb 4/18/2011 Consumer United States
Primary
Secondary
Concomitant
Asthenia Other Serious 10/1/2009 70 Male 235 lb 4/7/2011 United States
Primary
Secondary
Concomitant
Death Death 2/25/2004 79 Female 6/4/2011 Pharmacist United States
Primary
Concomitant
Death Death 12/7/2005 66 Female 6/6/2011 Physician New Zealand
Primary
Concomitant
Bladder Obstruction Hospitalization 2/1/2008 60 Male 6/4/2011 Physician United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization Male 6/4/2011 Physician United Kingdom
Primary
Concomitant
Abscess Hospitalization 6/27/2007 49 Female 6/5/2011 Physician United Kingdom
Primary
Concomitant
Blood Urea Increased Death 12/1/2007 81 Male 6/6/2011 Other Health Professional Canada
Primary
Concomitant
Empyema Death 3/19/2001 43 Male 6/9/2011 Physician Australia
Primary
Concomitant
Platelet Count Decreased Hospitalization 3/26/2009 35 Male 6/13/2011 Physician United Kingdom
Primary
Concomitant
Foot Fracture Hospitalization 7/22/2002 38 Male 317 lb 6/13/2011 Physician Canada
Primary
Concomitant
Interacting
Left Ventricular Failure Death Male 154 lb 6/11/2011 Consumer United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/24/2003 53 Male 6/13/2011 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 12/1/2004 72 Female 6/11/2011 Pharmacist United Kingdom
Primary
Concomitant
Urethral Stenosis Other Serious Male 6/13/2011 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious Female 6/16/2011 Physician United Kingdom
Primary
Concomitant
Drug Level Increased Hospitalization 4/20/2003 67 Female 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 1 Female 6/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Cerebrovascular Accident Death 82 Female 210 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 6/23/2010 51 Male 6/22/2011 Physician United States
Primary
Concomitant
Death Death 7/28/2010 73 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death 8/31/2010 62 Male 220 lb 6/22/2011 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 12/28/2010 71 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 1/4/2011 56 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Death 63 Female 220 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 2/2/2011 52 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Drug Level Increased Hospitalization 4/20/2003 67 Female 6/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 4/20/2003 67 Female 6/24/2011 Consumer United Kingdom
Primary
Secondary
Overdose Hospitalization 4/20/2003 1 Female 6/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 4/20/2003 67 Female 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Level Increased Hospitalization 4/20/2003 67 Female 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Level Increased Hospitalization 4/20/2003 67 Female 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Level Increased Hospitalization 4/20/2003 67 Female 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Level Increased Hospitalization 4/20/2003 67 Female 7/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 4/20/2003 67 Female 7/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Endocarditis Death 8/9/2010 63 Male 7/11/2011 Physician New Zealand
Primary
Concomitant
Lumbar Spinal Stenosis Other Serious Female 238 lb 6/29/2011 Physician Canada
Primary
Concomitant
Overdose Hospitalization 4/20/2003 67 Female 7/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 4/20/2003 67 Female 7/1/2011 Physician United Kingdom
Primary
Secondary
Syncope Other Serious 1/31/2011 65 Male 7/19/2011 Physician Ireland
Primary
Concomitant
Diarrhoea Hospitalization Female 7/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Level Increased Hospitalization 4/20/2003 67 Female 7/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization 1/1/2010 52 Male 7/14/2011 Physician United States
Primary
Concomitant
Diabetic Nephropathy Other Serious 1/1/2002 30 Male 239 lb 8/3/2011 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 6/25/2011 61 Male 8/3/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Faecal Incontinence Other Serious Female 8/8/2011 Physician United Kingdom
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 4/1/2011 71 Female 8/16/2011 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 8/30/2011 United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 7/1/2010 72 Female 111 lb 8/31/2011 Lawyer United States
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 4/21/2011 71 Female 9/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Lymphocyte Count Decreased Other Serious 11/2/2010 59 Female 9/28/2011 Physician United Kingdom
Primary
Concomitant
Leukopenia Hospitalization 11/2/2010 59 Female 10/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 11/2/2010 59 Female 10/7/2011 Pharmacist United Kingdom
Primary
Concomitant
Syncope Hospitalization 6/25/2011 61 Male 10/13/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious Male 11/4/2011 Colombia
Primary
Concomitant
Pain Hospitalization Female 11/11/2011 Consumer United States
Primary
Concomitant
Diabetic Neuropathy Disability 11/9/2011 69 Male 11/28/2011 Physician Colombia
Primary
Concomitant
Pain Hospitalization 6/13/2011 48 Female 258 lb 1/17/2012 Other Health Professional Poland
Primary
Concomitant
Neutrophil Count Increased Other Serious 5/12/2006 Female 3/28/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 5/12/2006 Female 4/17/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Monocyte Count Increased Other Serious 36 Female 4/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Agranulocytosis Life Threatening 3/18/2012 79 Female 5/2/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Disability 10/1/2009 68 Male 225 lb 5/9/2012 Consumer United States
Primary
Secondary
Concomitant
Hypertension Other Serious 5/12/2006 36 Female 5/11/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/1/2009 70 Male 235 lb 5/16/2012 Consumer United States
Primary
Secondary
Concomitant
Constipation Other Serious 5/12/2006 36 Female 5/24/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Hiatus Hernia Other Serious 5/12/2006 36 Female 5/24/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Disability 10/1/2009 70 Male 225 lb 5/24/2012 Consumer United States
Primary
Secondary
Concomitant
Sleep Disorder Disability 1/1/2009 69 Male 225 lb 5/29/2012 Consumer United States
Primary
Secondary
Concomitant
Malaise Other Serious 5/12/2006 36 Female 5/29/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 5/12/2006 36 Female 5/29/2012 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Disorder Other Serious 5/12/2006 36 Female 5/30/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fatigue Other Serious 10/22/2010 71 Male 236 lb 6/8/2012 Consumer United States
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 10/1/2009 70 Male 235 lb 6/11/2012 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Disorder Hospitalization 5/12/2006 36 Female 6/12/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Monocyte Count Increased Hospitalization 5/12/2006 36 Female 6/27/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abdominal Distension Death 4/28/2011 64 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Death 6/6/2011 49 Female 210 lb 6/28/2012 Pharmacist United States
Primary
Concomitant
Death Death 78 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Death Death 1/2/2012 60 Female 6/28/2012 Pharmacist United States
Primary
Concomitant
Dyspnoea Death 1/30/2012 66 Female 6/28/2012 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 5/10/2012 58 Female 145 lb 6/29/2012 Pharmacist United States
Primary
Concomitant
White Blood Cell Disorder Hospitalization 5/12/2006 36 Female 7/13/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 5/12/2006 36 Female 7/18/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 36 Female 7/20/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 7/12/2006 36 Female 7/13/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/12/2006 36 Female 7/26/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/12/2006 36 Female 7/27/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Potassium Decreased 7/18/2012 54 Female 197 lb 7/23/2012 Pharmacist United States
Primary
Concomitant
Abasia Other Serious 7/31/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 7/31/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Disability 7/31/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data