Clozapine combined with Fluoxetine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ileus Paralytic Other Serious 34 Male 172 lb 1/25/2006 United Kingdom
Primary
Concomitant
Neutrophil Count Increased Other Serious 3/14/2006 49 Male 4/10/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/28/2006 47 Male 4/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/8/2006 United States
Primary
Concomitant
Respiratory Failure Death 4/22/2006 30 Female 5/11/2006 United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 9/21/2005 35 Male 6/12/2006 United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Death 6/1/2006 45 Male 6/16/2006 United States
Primary
Concomitant
Myocardial Infarction Death 6/1/2006 45 Male 7/6/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/3/2006 60 Male 3/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/25/2006 23 Female 167 lb 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/31/2006 43 Male 3/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/13/2005 36 Male 1/27/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/22/2005 77 Female 134 lb 3/15/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/28/2005 32 Male 1/25/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/12/2005 51 Female 2/27/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 11/7/2005 31 Female 5/15/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/2/2005 61 Female 2/6/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/28/2005 25 Male 3/22/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/28/2005 50 Female 2/15/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/27/2006 37 Female 5/18/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 3/22/2006 32 Male 6/12/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 8/22/2005 33 Female 209 lb 1/11/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/6/2005 43 Male 1/6/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 2/8/2006 23 Male 3/21/2006 United States
Primary
Concomitant
Urine Odour Abnormal Other Serious 8/1/2006 14 Male 123 lb 11/13/2006 Physician Portugal
Primary
Secondary
Concomitant
Constipation Other Serious 12/3/2005 29 Male 12/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Posture Abnormal Other Serious 52 Female 1/19/2007 Other Health Professional Spain
Primary
Secondary
Weight Increased Other Serious 3/1/2003 42 Male 301 lb 1/25/2007 Consumer United States
Primary
Concomitant
Pulmonary Oedema Death 34 Male 3/9/2007 United Kingdom
Primary
Concomitant
Pulmonary Oedema Death 34 Male 3/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Death 34 Male 3/28/2007 United Kingdom
Primary
Concomitant
Pulmonary Oedema Death 34 Male 4/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 4/23/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/17/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/31/2007 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2001 50 Female 249 lb 4/2/2007 Consumer United States
Primary
Concomitant
Salivary Hypersecretion Other Serious 4/1/2006 32 Male 8/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocarditis Hospitalization 23 Male 8/17/2007 Australia
Primary
Secondary
Weight Increased Hospitalization 32 Male 225 lb 9/29/2007 Other Health Professional Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/21/2008 Female 6/30/2008 Physician Philippines
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/17/2002 Male 181 lb 7/1/2008 Physician France
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 11/24/2008 23 Female 2/4/2009 Physician United States
Primary
Concomitant
Urinary Retention Other Serious Male 4/15/2009 Physician United States
Primary
Secondary
Concomitant
Schizophrenia Hospitalization 6/18/2009 Male 154 lb 11/6/2009 Physician Kazakhstan
Primary
Secondary
Concomitant
Mesenteric Artery Thrombosis Death 6/20/2009 Female 12/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sedation Hospitalization 2/1/2010 36 Male 3/5/2010 Other Health Professional
Primary
Concomitant
Neutrophilia Other Serious 1/1/2002 58 Male 3/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 6/20/2008 48 Female 4/22/2010 United States
Primary
Concomitant
Myocardial Infarction Death 3/23/2010 47 Male 5/17/2010 Consumer Colombia
Primary
Concomitant
Platelet Count Decreased Other Serious 4/13/2010 69 Female 5/26/2010 Physician United Kingdom
Primary
Secondary
Suicide Attempt Other Serious 1/7/2010 52 Male 6/10/2010 Other Health Professional Denmark
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/7/2010 52 Male 6/28/2010 Other Health Professional Denmark
Primary
Concomitant
Tooth Abscess Other Serious 56 Male 7/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 5/22/2010 46 Male 7/28/2010 United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 2/1/2005 37 Male 8/9/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/23/2010 24 Female 174 lb 8/31/2010 Pharmacist United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 9/25/2010 67 Female 185 lb 11/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 2/1/2005 37 Male 12/2/2010 Other Health Professional United States
Primary
Secondary
Treatment Noncompliance Hospitalization 9/20/2010 45 Male 12/2/2010 United Kingdom
Primary
Secondary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 6/20/2008 48 Female 12/29/2010 United States
Primary
Concomitant
Pain Other Serious 1/1/2010 53 Female 175 lb 2/11/2011 Consumer United States
Primary
Concomitant
Sinobronchitis Other Serious 2/1/2005 37 Male 2/15/2011 Other Health Professional United States
Primary
Secondary
Unresponsive To Stimuli Death 2/20/2011 44 Male 242 lb 3/11/2011 Pharmacist United States
Primary
Secondary
Concomitant
Activities Of Daily Living Impaired Other Serious 40 Female 4/4/2011 Other Health Professional
Primary
Secondary
Neoplasm Malignant Other Serious Male 6/14/2011 Other Health Professional Canada
Primary
Concomitant
Asthenia Other Serious Male 6/14/2011 Physician United Kingdom
Primary
Concomitant
Gastritis Other Serious Male 6/14/2011 Physician United Kingdom
Primary
Concomitant
Sickle Cell Trait Other Serious 3/1/2006 20 Female 6/14/2011 Physician United Kingdom
Primary
Concomitant
Fractured Sacrum Other Serious 7/11/2005 55 Male 6/14/2011 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/17/2010 30 Male 6/30/2011 Physician United Kingdom
Primary
Concomitant
Fall Other Serious 9/1/2005 39 Female 7/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Differential White Blood Cell Count Abnormal Hospitalization 1/1/2011 66 Male 7/8/2011 Physician Ireland
Primary
Concomitant
Partial Seizures Other Serious 2/20/2011 39 Female 7/14/2011 Physician United Kingdom
Primary
Concomitant
Mania Hospitalization 6/22/2011 39 Male 7/15/2011 Pharmacist Australia
Primary
Concomitant
Hypertension Other Serious Female 7/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Social Avoidant Behaviour Hospitalization 9/1/2010 38 Female 7/25/2011 Physician Ireland
Primary
Secondary
Concomitant
Cardiac Arrest Death 1/18/2011 46 Male 7/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 9/1/2010 38 Female 7/25/2011 Physician Ireland
Primary
Secondary
Concomitant
Death Death Female 7/26/2011 Pharmacist United Kingdom
Primary
Concomitant
Myeloproliferative Disorder Other Serious 8/17/2010 30 Male 8/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 5/12/2011 44 Female 8/12/2011 Physician United Kingdom
Primary
Concomitant
Antipsychotic Drug Level Above Therapeutic Other Serious 3/16/2011 53 Male 8/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 7/15/2011 29 Male 209 lb 8/9/2011 Consumer Greece
Primary
Concomitant
Platelet Count Decreased Other Serious Male 8/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
C-reactive Protein Increased Death 1/12/2011 46 Male 8/19/2011 Physician United Kingdom
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 7/15/2011 29 Male 209 lb 8/23/2011 Physician Greece
Primary
Concomitant
Hypotension Other Serious Male 8/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hyperhidrosis Other Serious 1/1/2010 47 Male 8/26/2011 Physician United Kingdom
Primary
Interacting
Lethargy Other Serious 1/1/2010 47 Male 8/29/2011 Other Health Professional United Kingdom
Primary
Interacting
Alanine Aminotransferase Increased Other Serious Male 8/30/2011 Physician United Kingdom
Primary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 1/1/2010 47 Male 8/30/2011 Consumer United Kingdom
Primary
Concomitant
Cough Other Serious 1/1/2010 47 Male 8/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Hyperhidrosis Other Serious 1/1/2010 47 Male 8/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Sudden Death Death 8/5/2011 35 Female 320 lb 9/2/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Other Serious 1/1/2010 47 Male 8/26/2011 Physician
Primary
Secondary
Blood Alkaline Phosphatase Increased Other Serious 1/1/2011 47 Male 8/31/2011 Other Health Professional Denmark
Primary
Secondary
Disease Progression Other Serious 1/1/2005 52 Male 9/8/2011 Physician Canada
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 1/1/2005 52 Male 9/9/2011 Physician Canada
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2011 23 Female 137 lb 9/9/2011 Pharmacist Germany
Primary
Secondary
Lethargy Other Serious 1/1/2010 47 Male 9/12/2011 Other Health Professional United Kingdom
Primary
Interacting
Completed Suicide Death 7/21/2011 39 Male 9/13/2011 Physician United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 1/1/2010 47 Male 9/19/2011 Physician United Kingdom
Primary
Interacting
Hyperhidrosis Other Serious 1/1/2010 47 Male 9/14/2011 Physician
Primary
Secondary
Diarrhoea Other Serious 1/1/2010 47 Male 9/28/2011 Other Health Professional United Kingdom
Primary
Interacting
Non-hodgkin's Lymphoma Other Serious 7/4/2011 65 Male 9/28/2011 Physician United Kingdom
Primary
Concomitant
Body Temperature Increased Other Serious 7/4/2011 19 Male 10/2/2011 Consumer United Kingdom
Primary
Concomitant
Interacting
Affective Disorder Other Serious 4/9/2011 27 Female 10/4/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 4/9/2011 27 Female 10/4/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Obesity Other Serious 8/9/2011 33 Male 10/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Decreased Appetite Other Serious 1/1/2010 47 Male 10/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Diarrhoea Other Serious 1/1/2010 47 Male 10/19/2011 Physician United Kingdom
Primary
Concomitant
Interacting
Drug Interaction Other Serious 1/1/2010 47 Male 10/20/2011 Consumer United Kingdom
Primary
Concomitant
Cough Other Serious 1/1/2011 47 Male 10/14/2011 Physician Denmark
Primary
Secondary
Concomitant
Diarrhoea Other Serious 1/1/2010 47 Male 10/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Diarrhoea Other Serious 1/1/2010 47 Male 10/18/2011 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2010 47 Male 10/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diabetic Neuropathy Disability 11/9/2011 69 Male 11/28/2011 Physician Colombia
Primary
Concomitant
Respiratory Arrest Death 1/1/2010 43 Female 12/23/2011 Physician United States
Primary
Secondary
Death Death 43 Female 12/30/2011 Physician United States
Primary
Secondary
Abnormal Behaviour Hospitalization 1/5/2012 Other Health Professional Turkey
Primary
Concomitant
Psychotic Disorder Hospitalization 1/5/2012 Other Health Professional Turkey
Primary
Concomitant
Salivary Hypersecretion Other Serious Female 1/9/2012 Physician Argentina
Primary
Concomitant
Respiratory Arrest Death 1/1/2010 43 Female 1/11/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 1/1/2010 43 Female 1/9/2012 Physician United States
Primary
Secondary
Leukocytosis Other Serious 1/24/2012 Physician Germany
Primary
Concomitant
Cardio-respiratory Arrest Death 43 Female 2/2/2012 Physician United States
Primary
Secondary
Cough Other Serious 1/1/2010 47 Male 2/28/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Gastrointestinal Motility Disorder Hospitalization 61 Female 2/29/2012 Other Health Professional United States
Primary
Concomitant
Abdominal Distension Hospitalization 61 Female 3/1/2012 Other Health Professional United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 1/1/2010 47 Male 3/1/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Cough Other Serious 1/1/2010 47 Male 3/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Interaction Other Serious 1/1/2011 47 Male 2/28/2012 Physician Denmark
Primary
Secondary
Concomitant
C-reactive Protein Increased Other Serious 1/1/2010 47 Male 2/27/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 1/1/2010 47 Male 3/1/2012 Consumer United Kingdom
Primary
Concomitant
Abdominal Pain Other Serious 1/1/2010 47 Male 2/28/2012 Physician
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 1/1/2010 47 Male 3/5/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 1/1/2010 47 Male 3/7/2012 Physician
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 1/1/2010 47 Male 3/13/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Cardiac Arrest Death 43 Female 4/2/2012 Other Health Professional United States
Primary
Secondary
Drug Level Above Therapeutic Hospitalization 61 Female 4/12/2012 Physician United States
Primary
Concomitant
Interacting
Psychotic Disorder Hospitalization 61 Female 4/13/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Antipsychotic Drug Level Above Therapeutic Hospitalization 61 Female 4/13/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Hallucination, Auditory Hospitalization 61 Female 4/13/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Drug Level Above Therapeutic Hospitalization 61 Female 4/15/2012 Physician United States
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 61 Female 4/15/2012 Physician United States
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 61 Female 4/19/2012 Other Health Professional United States
Primary
Interacting
Ileus Paralytic Hospitalization 61 Female 4/22/2012 Other Health Professional United States
Primary
Interacting
Drug Interaction Other Serious 4/27/2012 Physician United States
Primary
Concomitant
Interacting
Completed Suicide Death 43 Female 4/27/2012 Physician United States
Primary
Secondary
Small Intestinal Obstruction Other Serious 61 Female 4/27/2012 Physician United States
Primary
Secondary
Concomitant

Drug Data