Clozapine combined with Diazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Aneurysm Death 43 Male 1/11/2006 United States
Primary
Concomitant
Ileus Paralytic Other Serious 34 Male 172 lb 1/25/2006 United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 12/25/2005 39 Male 146 lb 1/31/2006 Other Health Professional France
Primary
Secondary
Wound Infection Staphylococcal Hospitalization 55 Male 2/7/2006 United Kingdom
Primary
Secondary
Myalgia Hospitalization 12/25/2005 39 Male 146 lb 2/20/2006 Other Health Professional France
Primary
Secondary
Tooth Disorder Hospitalization 1/21/2006 36 Male 3/9/2006 Physician Finland
Primary
Concomitant
Ileus Paralytic Other Serious 11/15/2005 34 Male 172 lb 3/11/2006 United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/22/2005 38 Male 245 lb 4/1/2005 Pharmacist United States
Primary
Concomitant
Death Death 38 Male 4/3/2006 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 32 Male 6/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Death 42 Male 6/12/2006 Consumer United Kingdom
Primary
Secondary
Pyrexia Death 5/6/2006 42 Male 6/8/2006 Nigeria
Primary
Secondary
Granulocytopenia Required Intervention 1/9/2006 48 Male 207 lb 5/24/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 2/7/2006 55 Female 3/22/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/2/2005 56 Male 244 lb 1/11/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/28/2005 50 Female 2/15/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/28/2005 39 Male 6/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/30/2006 43 Male 118 lb 5/15/2006 Consumer United States
Primary
Concomitant
Premature Baby Other Serious 10/4/2005 0 Female 10/19/2006 Physician Germany
Primary
Concomitant
Constipation Other Serious 12/3/2005 29 Male 12/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Death 12/1/2006 28 Female 1/16/2007 United Kingdom
Primary
Concomitant
Extrapyramidal Disorder Other Serious 1/1/2005 37 Female 2/28/2007 Consumer Germany
Primary
Concomitant
Transaminases Increased Other Serious 11/20/2006 44 Female 238 lb 3/8/2007 Physician Germany
Primary
Concomitant
Neuroleptic Malignant Syndrome Death 45 Male 3/28/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 34 Male 9/4/2007 Other Health Professional Singapore
Primary
Concomitant
Suicide Attempt Life Threatening 11/18/2006 Male 9/21/2007 Other Health Professional France
Primary
Concomitant
Necrotising Colitis Life Threatening 34 Male 9/21/2007 Physician Singapore
Primary
Concomitant
Necrosis Ischaemic Life Threatening 34 Male 9/14/2007 Physician Singapore
Primary
Concomitant
Septic Shock Death 34 Male 10/29/2007 Physician United Kingdom
Primary
Concomitant
Septic Shock Death 1/1/2001 Male 11/7/2007 Physician United Kingdom
Primary
Concomitant
Death Death 12/15/2007 33 Male 12/20/2007 Physician Brazil
Primary
Secondary
Toxic Encephalopathy Other Serious 4/1/2007 Female 1/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Suicidal Ideation Death 8/24/2007 37 Male 4/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Hepatitis Cholestatic Hospitalization 2/5/2008 22 Female 5/1/2008 Other Health Professional France
Primary
Concomitant
Supraventricular Tachycardia Other Serious 5/16/2008 33 Female 7/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 5/16/2008 33 Female 7/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 6/6/2007 Male 148 lb 7/3/2008 Physician Germany
Primary
Concomitant
Urinary Tract Obstruction Hospitalization 1/1/1991 47 Male 7/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/17/2007 45 Male 7/29/2008 Physician United Kingdom
Primary
Concomitant
Drug Level Increased Hospitalization 1/1/2007 Male 141 lb 7/30/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 3/12/2008 Male 8/26/2008 Physician United States
Primary
Concomitant
Urine Flow Decreased Other Serious 7/1/2008 25 Male 159 lb 12/5/2008 Physician Russian Federation
Primary
Concomitant
Vomiting Other Serious 38 Male 1/13/2009 Other Health Professional Hong Kong
Primary
Concomitant
Pulmonary Oedema Death 38 Male 1/26/2009 Other Health Professional Hong Kong
Primary
Concomitant
Urinary Retention Hospitalization 2/9/2009 59 Male 152 lb 4/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Suprapubic Pain Hospitalization 2/7/2009 59 Male 3/31/2009 Other Health Professional United Kingdom
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious Male 6/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 6/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Other Serious 4/9/2003 52 Male 147 lb 6/19/2009 United States
Primary
Concomitant
Vomiting Other Serious Male 6/18/2009 United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 1/1/2008 29 Female 6/22/2009 Pharmacist Netherlands
Primary
Concomitant
Cerebral Hypoperfusion Other Serious 27 Male 7/14/2009 Other Health Professional South Africa
Primary
Secondary
Pulmonary Oedema Other Serious 26 Male 8/17/2009
Primary
Secondary
Concomitant
Temporomandibular Joint Syndrome Other Serious 56 Female 8/14/2009 Canada
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious Male 8/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 3/29/2009 29 Male 9/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 7/31/2009 52 Male 10/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 10/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 10/14/2009 Other Health Professional France
Primary
Secondary
Concomitant
Schizophrenia Other Serious 5/1/2005 32 Male 10/19/2009
Primary
Concomitant
Syncope Other Serious 7/31/2009 52 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Salivary Hypersecretion Hospitalization 7/31/2009 52 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 7/31/2009 52 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 7/31/2009 52 Male 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 7/31/2009 52 Male 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 11/13/2009 United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 7/31/2009 52 Male 11/19/2009
Primary
Secondary
Concomitant
Septic Shock Death 1/1/2001 Male 11/30/2009 Physician United Kingdom
Primary
Concomitant
Overdose Hospitalization 6/6/2007 Male 148 lb 12/1/2009 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Other Serious 48 Male 12/4/2009 Physician Ireland
Primary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 12/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/4/2008 37 Male 12/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 2/4/2008 37 Male 12/17/2009 Pharmacist Denmark
Primary
Secondary
Syncope Hospitalization 7/31/2009 52 Male 1/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 3/25/2009 29 Male 1/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 24 Male 2/4/2010 United Kingdom
Primary
Concomitant
Interacting
Suicide Attempt Hospitalization 1/21/2004 36 Male 2/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 1/21/2004 36 Male 3/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Restlessness Other Serious 11/1/2009 24 Male 194 lb 3/10/2010 Physician Germany
Primary
Secondary
Concomitant
Skin Discolouration Death 12/15/2007 33 Male 4/5/2010 Physician Brazil
Primary
Secondary
Concomitant
Skin Injury Other Serious 10/8/2009 36 Male 4/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Drug Interaction Death 12/15/2007 33 Male 4/13/2010 Physician Brazil
Primary
Secondary
Interacting
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 6/20/2008 48 Female 4/22/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 5/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Memory Impairment Other Serious 32 Male 6/22/2010 Other Health Professional Switzerland
Primary
Secondary
Granulocytopenia Other Serious 44 Female 180 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 4/12/2010 25 Male 143 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 36 Male 6/30/2010 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Fall Other Serious 6/1/2010 58 Male 184 lb 7/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 42 Male 7/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Neuroleptic Malignant Syndrome Hospitalization 36 Male 7/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Fall Hospitalization 4/1/2008 58 Female 190 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Other Serious 8/12/2009 56 Male 117 lb 8/26/2010 Physician
Primary
Secondary
Concomitant
Torticollis Hospitalization 34 Male 8/25/2010 Physician Greece
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 8/12/2009 56 Male 117 lb 9/3/2010 Physician
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 10/6/2009 56 Male 9/3/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Fall Other Serious 6/1/2010 58 Male 184 lb 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Presyncope Other Serious 8/1/2009 56 Male 117 lb 9/15/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 1/1/2009 56 Male 117 lb 9/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 8/12/2009 9/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 39 Female 10/12/2010
Primary
Secondary
Psychotic Disorder Required Intervention 39 Female 10/5/2010 Other Health Professional United States
Primary
Secondary
Urinary Incontinence Other Serious 29 Female 10/28/2010 Physician United Kingdom
Primary
Secondary
Tremor Required Intervention 39 Female 10/18/2010 Physician United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Required Intervention 39 Female 10/18/2010 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 8/12/2009 56 Male 117 lb 10/29/2010 Physician
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 36 Male 11/1/2010 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Interacting
Psychomotor Hyperactivity Hospitalization 4/7/2010 23 Male 11/8/2010 Argentina
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 36 Male 11/9/2010
Primary
Secondary
Neuroleptic Malignant Syndrome Hospitalization 42 Male 11/9/2010
Primary
Secondary
Trismus Other Serious 36 Male 11/10/2010 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Tremor Other Serious 10/6/2009 56 Male 11/10/2010 Denmark
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Female 11/18/2010 Pharmacist United Kingdom
Primary
Concomitant
Tremor Other Serious 1/1/2009 56 Male 117 lb 11/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Presyncope Other Serious 8/1/2009 56 Male 117 lb 11/19/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 29 Female 12/7/2010 Physician United Kingdom
Primary
Secondary
Urinary Tract Infection Other Serious Female 12/7/2010 Pharmacist United Kingdom
Primary
Concomitant
Respiratory Arrest Death 9/8/2010 32 Male 11/24/2010 Physician Austria
Primary
Secondary
Concomitant
Fall Other Serious 6/1/2010 58 Male 184 lb 7/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Other Serious Male 12/23/2010 Other Health Professional Slovenia
Primary
Interacting
Thrombocytosis Other Serious 41 Male 12/28/2010 Other Health Professional Netherlands
Primary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 6/20/2008 48 Female 12/29/2010 United States
Primary
Concomitant
Somnolence Other Serious 54 Male 1/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Body Temperature Increased Hospitalization 41 Male 1/28/2011 Other Health Professional Netherlands
Primary
Concomitant
Helicobacter Gastritis Other Serious 41 Male 1/20/2011
Primary
Secondary
Neutropenia Other Serious 12/29/2010 25 Male 2/2/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 35 Male 2/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 35 Male 2/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/29/2010 25 Male 2/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Other Serious 41 Male 2/14/2011 Other Health Professional Netherlands
Primary
Concomitant
Haemoglobin Decreased Hospitalization 41 Male 2/14/2011 Other Health Professional Netherlands
Primary
Concomitant
Pneumonia Death 35 Male 2/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 35 Male 2/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/29/2010 25 Male 2/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 35 Male 2/14/2011 Other Health Professional
Primary
Secondary
Concomitant
Myocarditis Other Serious 3/1/2011 Other Health Professional Australia
Primary
Concomitant
Renal Impairment Other Serious 3/1/2011 Other Health Professional Australia
Primary
Concomitant
Renal Impairment Death 3/18/2011 Other Health Professional Australia
Primary
Concomitant
Back Pain Disability 10/1/2009 68 Male 235 lb 3/30/2011 Consumer United States
Primary
Secondary
Concomitant
Abasia Other Serious 10/1/2009 70 Male 235 lb 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Myalgia Other Serious 1/1/2009 69 Male 236 lb 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Nausea Disability 10/1/2009 69 Male 235 lb 4/14/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Irritation Disability 10/1/2009 68 Male 235 lb 4/13/2011 Consumer United States
Primary
Concomitant
Bone Marrow Disorder Other Serious Male 4/5/2011 Physician Ireland
Primary
Concomitant
Vomiting Disability 10/1/2009 70 Male 235 lb 4/18/2011 Consumer United States
Primary
Secondary
Concomitant
Asthenia Other Serious 10/1/2009 70 Male 235 lb 4/7/2011 United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Other Serious 4/1/2011 35 Male 5/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Electroencephalogram Abnormal Other Serious 30 Male 5/10/2011 Physician Germany
Primary
Concomitant
Hypoglycaemia Other Serious 10/3/2010 46 Male 5/11/2011 Other Health Professional Spain
Primary
Concomitant
Overdose Death 2/8/2011 61 Female 5/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting

Drug Data