Clozapine combined with Cogentin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Failure Death 9/17/2005 68 Female 2/20/2006 Physician Canada
Primary
Secondary
Concomitant
Respiratory Failure Death 9/17/2005 68 Female 2/24/2006 Physician Canada
Primary
Secondary
Concomitant
Death Death 1/1/2005 42 Male 211 lb 3/28/2005 Physician United States
Primary
Concomitant
Neutropenia Required Intervention 3/24/2005 45 Female 210 lb 6/2/2005 Physician United States
Primary
Concomitant
Suicidal Ideation Hospitalization 4/1/2005 46 Male 5/13/2005 Physician United States
Primary
Concomitant
Leukocytosis Hospitalization 4/1/2004 46 Male 5/10/2005 Other Health Professional United States
Primary
Concomitant
Neutropenia Other Serious 5/9/2002 34 Female 218 lb 12/20/2004 Physician United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 11/1/2004 39 Female 12/20/2004 Other Health Professional United States
Primary
Concomitant
Convulsion Hospitalization 10/27/2004 48 Female 12/2/2004 Physician United States
Primary
Concomitant
Dysmenorrhoea Hospitalization 1/18/2005 44 Female 3/14/2005 Other Health Professional United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 10/19/2006 24 Male 11/22/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased 17 Female 172 lb 2/2/2007 Physician United States
Primary
Concomitant
Death Death 10/1/2006 Male 235 lb 2/2/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/28/2006 44 Male 2/21/2007 United States
Primary
Secondary
Concomitant
Ultrasound Liver Abnormal Hospitalization 9/19/2005 Male 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Required Intervention 4/10/2007 46 Female 180 lb 5/31/2007 United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/28/2007 Male 7/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Sinusitis Required Intervention 5/16/2007 42 Female 196 lb 8/3/2007 United States
Primary
Concomitant
Vomiting Other Serious 2/1/2007 Male 180 lb 10/11/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/1/2006 41 Female 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia 7/5/2006 37 Male 292 lb 7/12/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/1/2006 41 Female 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Myocarditis Death 4/23/2007 Male 408 lb 4/5/2008 United States
Primary
Concomitant
Oral Intake Reduced Hospitalization 11/1/2007 51 Male 204 lb 4/8/2008 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 4/23/2008 48 Female 5/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 4/23/2008 48 Female 5/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/29/2008 Norway
Primary
Concomitant
Intestinal Obstruction Hospitalization 7/15/2008 46 Male 7/25/2008 Pharmacist United States
Primary
Concomitant
Rash Other Serious Female 8/25/2008 Other Health Professional United States
Primary
Concomitant
Rash Other Serious Female 9/5/2008 Pharmacist United States
Primary
Concomitant
Haemoptysis 11/7/2008 51 Male 12/15/2008 Other Health Professional United States
Primary
Concomitant
Tongue Disorder Hospitalization 9/18/2008 Male 182 lb 2/12/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/14/2009 48 Male 100 lb 3/19/2009 Pharmacist United States
Primary
Concomitant
Drug Level Increased Death 8/28/2008 Female 6/17/2009 Physician United States
Primary
Concomitant
Overdose Other Serious 12/15/2006 Male 142 lb 7/6/2009 Physician United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2003 29 Male 328 lb 7/9/2009 United States
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 10/14/2008 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 10/14/2008 53 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 61 Female 160 lb 8/5/2009 Physician United States
Primary
Concomitant
Diabetic Ketoacidosis Other Serious 5/7/2003 18 Female 180 lb 9/23/2009 United States
Primary
Concomitant
Ill-defined Disorder Disability Female 209 lb 10/15/2009 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Other Serious 2/20/2004 41 Male 208 lb 11/4/2009 United States
Primary
Concomitant
Hypoglycaemia Other Serious 2/20/2004 41 Male 208 lb 11/30/2009 United States
Primary
Concomitant
Sedation 12/23/2008 24 Male 190 lb 1/20/2009 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Required Intervention 10/26/2008 Male 166 lb 11/18/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 57 Male 3/22/2010 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 57 Male 4/20/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 30 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 44 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 38 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 30 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 38 Male 6/24/2010 Physician United States
Primary
Concomitant
Leukopenia Other Serious 43 Female 166 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 9 Female 81 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 8/3/2009 28 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 54 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 23 Male 189 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 9/8/2009 60 Male 180 lb 6/24/2010 Physician United States
Primary
Concomitant
Granulocytopenia Other Serious 53 Female 189 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 25 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 47 Male 180 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Death 8/1/2009 74 Female 188 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Cerebrovascular Disorder Death 57 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 11/17/2009 30 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 11/17/2009 55 Male 6/24/2010 Physician United States
Primary
Concomitant
Leukopenia Other Serious 11/16/2009 45 Female 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 12/10/2009 38 Male 242 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 12/9/2009 43 Male 212 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 11/24/2009 25 Male 161 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 12/23/2009 31 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Lung Cancer Metastatic Death 53 Male 188 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Granulocytopenia Other Serious 1/4/2010 60 Female 6/24/2010 Physician United States
Primary
Concomitant
Leukopenia Other Serious 2/1/2010 20 Female 125 lb 6/24/2010 Physician United States
Primary
Concomitant
Granulocytopenia Other Serious 2/16/2010 31 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 1/29/2010 76 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 12/28/2009 66 Male 6/24/2010 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 2/24/2010 39 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 2/21/2010 58 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 64 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Granulocytopenia Other Serious 12/30/2009 24 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 3/3/2010 31 Male 6/24/2010 Physician United States
Primary
Concomitant
Sepsis Hospitalization 3/5/2010 57 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 53 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 3/14/2010 45 Male 6/24/2010 Physician United States
Primary
Concomitant
Leukopenia Other Serious 4/15/2010 31 Male 226 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 4/14/2010 27 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 16 Male 6/24/2010 Physician United States
Primary
Concomitant
Leukopenia Other Serious 21 Male 6/24/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 36 Male 8/5/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/1/2003 25 Male 12/12/2010 Physician Canada
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 6/6/2009 48 Male 1/17/2011 Consumer United States
Primary
Secondary
Concomitant
Schizophrenia Hospitalization 6/6/2009 48 Male 1/25/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Level Below Therapeutic 5/6/2010 43 Male 1/27/2011 Pharmacist United States
Primary
Concomitant
Incorrect Dose Administered Other Serious 2/23/2011 42 Female 130 lb 3/3/2011 Physician United States
Primary
Secondary
Concomitant
Hydrocephalus Other Serious 1/1/2010 47 Male 240 lb 3/18/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Administered At Inappropriate Site Other Serious 2/23/2011 42 Female 130 lb 3/21/2011 Physician United States
Primary
Secondary
Concomitant
Drug Administered At Inappropriate Site Other Serious 2/23/2011 42 Female 130 lb 3/21/2011 Physician United States
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 3/22/2011 39 Female 5/18/2011 Pharmacist United States
Primary
Concomitant
Sudden Death Death 4/20/2002 43 Male 6/8/2011 Other Health Professional Canada
Primary
Concomitant
Laryngeal Cancer Life Threatening 2/1/2008 51 Male 6/12/2011 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 12/23/2009 31 Male 6/22/2011 Physician United States
Primary
Concomitant
Leukopenia Other Serious 5/6/2010 50 Male 140 lb 6/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Choking Death 5/20/2010 51 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 6/11/2010 54 Male 210 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 6/15/2010 85 Female 6/22/2011 Physician United States
Primary
Concomitant
Granulocytopenia Other Serious 6/22/2010 54 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 7/12/2010 22 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 7/27/2010 51 Male 201 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 7/19/2010 24 Male 6/22/2011 Physician United States
Primary
Concomitant
Granulocytopenia Other Serious 7/23/2010 27 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Asthma Death 47 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 9/1/2010 19 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 9/11/2010 32 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 9/13/2010 56 Female 193 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 9/21/2010 49 Female 150 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia 10/14/2010 35 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 10/26/2010 51 Female 119 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 11/18/2010 28 Female 148 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 11/24/2010 67 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 12/13/2010 53 Male 175 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 12/16/2010 21 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 1/3/2011 52 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 63 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 1/19/2011 26 Female 220 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 1/18/2011 49 Male 6/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 1/21/2011 62 Female 160 lb 6/22/2011 Physician United States
Primary
Concomitant
Granulocytopenia Other Serious 3/2/2011 58 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 3/9/2011 52 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Lung Neoplasm Malignant Death 71 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Death Death 3/27/2011 77 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 4/12/2011 35 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 4/19/2011 26 Male 154 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Neoplasm Malignant Death 3/21/2011 57 Male 144 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 9/22/2010 50 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Blood Prolactin Increased Other Serious Female 6/23/2011 Physician United States
Primary
Concomitant
Neutrophil Count Increased Other Serious 7/12/2011 31 Male 7/27/2011 Pharmacist Canada
Primary
Concomitant
Malaise Life Threatening 8/22/2011 60 Female 8/29/2011 Other Health Professional Canada
Primary
Concomitant
Gait Disturbance Life Threatening 8/22/2011 60 Female 8/30/2011 Other Health Professional Canada
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious Male 254 lb 9/8/2011 Physician Canada
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 5/1/2006 57 Female 205 lb 9/22/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Decreased Other Serious 1/1/1998 27 Male 201 lb 9/22/2011 United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 8/22/2011 60 Female 10/3/2011 Other Health Professional Canada
Primary
Concomitant
Overdose Other Serious Female 10/20/2011 Consumer New Zealand
Primary
Concomitant
Gait Disturbance 1/1/2010 43 Male 12/16/2011 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2012 39 Male 306 lb 3/2/2012 Consumer United States
Primary
Concomitant
Granulocytopenia Other Serious 5/19/2011 16 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 6/4/2011 33 Male 161 lb 6/28/2012 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 6/1/2011 22 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 6/24/2011 60 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 3/29/2011 51 Female 6/28/2012 Pharmacist United States
Primary
Concomitant

Drug Data