Clozapine combined with Clozaril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Failure Death 9/17/2005 68 Female 2/20/2006 Physician Canada
Primary
Secondary
Concomitant
Respiratory Failure Death 9/17/2005 68 Female 2/24/2006 Physician Canada
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 46 Male 265 lb 4/13/2006 Physician United States
Primary
Concomitant
Schizophrenia Other Serious 1/1/2005 Female 5/1/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/21/2000 40 Female 6/1/2006 Physician United States
Primary
Secondary
Concomitant
Social Avoidant Behaviour Other Serious 42 Male 8/24/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/1/2005 35 Male 10/30/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/1/2006 36 Male 12/2/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/14/2006 58 Male 1/22/2007 Physician United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 1/1/1995 Male 2/20/2007 Consumer United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 1/1/1995 Male 2/20/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/28/2006 44 Male 2/21/2007 United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 1/1/1995 Male 2/20/2007 Consumer United States
Primary
Secondary
Concomitant
Hysterectomy Other Serious 11/1/2006 43 Female 3/10/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/3/2006 42 Male 3/18/2007 United States
Primary
Secondary
Hallucination, Auditory Other Serious 10/13/2004 53 Male 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 1/1/1997 46 Female 161 lb 11/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2005 Female 270 lb 11/6/2006 Consumer United States
Primary
Secondary
Ultrasound Liver Abnormal Hospitalization 9/19/2005 Male 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Neutrophil Count Abnormal Other Serious 12/1/2005 50 Female 11/6/2006 Physician United States
Primary
Secondary
Diabetes Mellitus Death 1/1/2004 Female 4/5/2007 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 8/1/2002 21 Male 4/18/2007 Physician United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 6/23/2007 33 Female 8/1/2007 Physician Australia
Primary
Secondary
Concomitant
Hypertensive Heart Disease Death 1/1/2004 40 Female 9/26/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/1/2006 41 Female 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 7/1/2004 45 Female 2/5/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Grip Strength Decreased Hospitalization 2/1/2007 46 Female 150 lb 2/6/2008 Consumer United States
Primary
Concomitant
Skin Neoplasm Excision Other Serious 1/1/2005 60 Female 2/5/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/1/2006 41 Female 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Grip Strength Decreased Hospitalization 2/1/2007 46 Female 150 lb 3/10/2008 Consumer United States
Primary
Concomitant
Rash Generalised Other Serious 20 Male 3/9/2008 Consumer
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 20 Male 4/9/2008 Consumer United States
Primary
Secondary
Concomitant
Malaise Other Serious 4/19/2008 Female 6/2/2008 Physician Canada
Primary
Concomitant
Malaise Other Serious 4/19/2008 Female 6/2/2008 Physician Canada
Primary
Concomitant
White Blood Cell Disorder Other Serious Male 8/8/2008 Other Health Professional United States
Primary
Secondary
Violence-related Symptom Other Serious Male 154 lb 9/9/2008 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 8/12/2008 Male 9/9/2008 Consumer South Africa
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 7/23/2000 Male 11/6/2008 Physician Australia
Primary
Secondary
Brain Neoplasm Hospitalization 11/27/2008 Consumer United Kingdom
Primary
Secondary
Death Death 11/16/2008 Female 11/28/2008 Pharmacist United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2008 42 Female 11/19/2008 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 7/23/2000 Male 12/4/2008 Physician Australia
Primary
Secondary
Metastases To Central Nervous System Hospitalization Female 12/5/2008 Physician United Kingdom
Primary
Secondary
Varicose Vein Hospitalization 12/16/2008 Female 1/2/2009 Physician New Zealand
Primary
Concomitant
Death Death 11/16/2008 Female 1/16/2009 Pharmacist United Kingdom
Primary
Concomitant
Death Death 11/16/2008 Female 1/27/2009 Pharmacist United Kingdom
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious Female 2/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/21/2009 Female 2/13/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Surgery Hospitalization Male 3/19/2009 Other Health Professional Australia
Primary
Secondary
Surgery Hospitalization 3/4/2009 Male 3/26/2009 Other Health Professional Australia
Primary
Secondary
Suicidal Ideation Hospitalization 3/14/2002 38 Female 276 lb 4/10/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious Male 4/15/2009 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/3/2009 Male 5/15/2009 Other Health Professional United States
Primary
Secondary
Suicide Attempt Other Serious Female 5/21/2009 Other Health Professional Canada
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/3/2009 Male 5/21/2009 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/3/2009 Male 6/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 35 Male 183 lb 6/24/2009 United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2003 29 Male 328 lb 7/9/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 10/20/2000 53 Female 207 lb 7/9/2009 United States
Primary
Concomitant
Lymphoma Death Male 7/9/2009 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 4/1/2009 49 Female 8/12/2009 United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 10/1/2007 Male 8/18/2009 Physician New Zealand
Primary
Secondary
Suicide Attempt Other Serious Female 8/19/2009 Other Health Professional Canada
Primary
Secondary
Hysterectomy Other Serious 11/1/2006 Female 8/25/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/9/2009 Female 11/3/2009 Other Health Professional Ireland
Primary
Secondary
Concomitant
Terminal State Other Serious 70 Female 11/5/2009 United Kingdom
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious Male 11/30/2009 Physician United States
Primary
Secondary
Urinary Incontinence Other Serious 7/10/2009 Male 12/2/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 12/21/2009 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious Female 12/29/2009 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 12/15/2009 Male 1/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 1/1/2003 47 Male 257 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Hospitalization Male 2/2/2010 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/15/2010 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/12/2009 Female 2/16/2010 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/21/2010 Female 2/17/2010 Physician United States
Primary
Secondary
Obstructive Airways Disorder Other Serious Female 3/1/2010 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/10/2009 Male 3/2/2010 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/1/2009 Female 3/4/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/10/2009 Male 3/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Treatment Failure Hospitalization Female Consumer United States
Primary
Secondary
Tardive Dyskinesia Other Serious Male 4/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 20 Female 203 lb 4/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Repetitive Speech Other Serious 20 Female 203 lb 4/15/2010 Other Health Professional
Primary
Secondary
Concomitant
Death Death 5/11/2010 25 Male 5/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/10/2009 42 Male 5/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Death 5/11/2010 25 Male 7/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious Female 8/13/2010 Canada
Primary
Secondary
Overdose Death 5/11/2010 25 Male 8/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious Female 8/23/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Tachycardia Other Serious 5/25/2008 28 Male 8/24/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vessel Puncture Site Haematoma Other Serious 5/11/2010 25 Male 280 lb 8/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Female Other Serious 49 Female 9/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Obstruction Other Serious 1/1/2010 55 Male 10/15/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Hospitalization Female 10/18/2010 Other Health Professional New Zealand
Primary
Concomitant
Platelet Count Decreased Other Serious 49 Female 10/11/2010 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Obstruction Other Serious 1/1/2010 55 Male 10/21/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 49 Female 10/23/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 49 Female 11/6/2010 United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death Male 11/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Death Death 7/28/2010 Male 12/21/2010 Canada
Primary
Secondary
Muscle Twitching Other Serious Male 1/24/2011 United Kingdom
Primary
Secondary
General Physical Health Deterioration Other Serious 49 Female 1/17/2011 United Kingdom
Primary
Secondary
Concomitant
Hepatitis Death 6/7/2011 Other Health Professional Canada
Primary
Secondary
Pyrexia Other Serious Female 6/9/2011 Physician Canada
Primary
Concomitant
General Physical Health Deterioration Other Serious 8/1/2010 49 Female 8/17/2011 Physician
Primary
Secondary
Concomitant
Tachycardia Other Serious Male 10/27/2011 Consumer United Kingdom
Primary
Secondary
Back Pain Other Serious 6/27/2003 40 Male 10/31/2011 Physician Australia
Primary
Secondary
Concomitant
Skeletal Injury Other Serious 6/27/2003 40 Male 11/2/2011 Physician Australia
Primary
Secondary
Concomitant
Pneumonia Other Serious Female 11/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Disability 11/15/2010 41 Male 12/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Fatigue Other Serious Male 1/31/2012 Consumer United States
Primary
Secondary
Drug Ineffective Hospitalization 52 Male 2/2/2012 Consumer United States
Primary
Secondary
Poikilocytosis Other Serious 1/1/2011 60 Male 2/2/2012 Physician Ireland
Primary
Concomitant
Deep Vein Thrombosis Death Female 2/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Bundle Branch Block Right Other Serious 1/19/2012 31 Male 2/21/2012 Physician Australia
Primary
Secondary
Haemoglobin Decreased Other Serious 1/1/2011 60 Male 2/28/2012 Other Health Professional Ireland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/12/2011 46 Female 3/6/2012 Other Health Professional Australia
Primary
Secondary
Malaise Hospitalization 52 Male 3/9/2012 Consumer United States
Primary
Secondary
White Blood Cell Count Increased Other Serious Female 3/12/2012 Pharmacist Australia
Primary
Secondary
Cardiac Disorder Other Serious Female 3/12/2012 Consumer Australia
Primary
Secondary
Neoplasm Malignant Other Serious Female 3/12/2012 Other Health Professional Australia
Primary
Secondary
Sedation Other Serious Female 3/12/2012 Pharmacist Australia
Primary
Secondary
Neutrophil Count Increased Other Serious Female 3/14/2012 Other Health Professional Australia
Primary
Secondary
White Blood Cell Count Increased Other Serious Female 3/14/2012 Other Health Professional Australia
Primary
Secondary
Death Death Female 3/19/2012 Other Health Professional Australia
Primary
Secondary
Cerebrovascular Accident Death 1/1/2012 77 Female 3/20/2012 Consumer New Zealand
Primary
Secondary
Mood Swings Other Serious 58 Female 3/21/2012 Other Health Professional Sweden
Primary
Secondary
Concomitant
Decreased Activity Other Serious 58 Female 3/21/2012 Other Health Professional Sweden
Primary
Secondary
Concomitant
Fatigue Hospitalization Male 3/22/2012 Physician United States
Primary
Secondary
Loss Of Consciousness Hospitalization 2/1/2012 45 Female 3/26/2012 Other Health Professional Australia
Primary
Secondary
Sedation Other Serious 2/3/2012 79 Female 3/26/2012 Consumer Australia
Primary
Secondary
Cardiac Disorder Hospitalization 2/3/2012 79 Female 3/26/2012 Consumer Australia
Primary
Secondary
Asthenia Other Serious 5/10/2010 39 Male 8/10/2010 Physician United States
Primary
Concomitant
Eating Disorder Hospitalization Male 4/4/2012 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/15/2007 52 Male 4/5/2012 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/24/2007 28 Male 4/10/2012 Physician Australia
Primary
Secondary
Nausea Other Serious 1/1/2003 29 Male 4/12/2012 Physician Australia
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 3/29/2012 67 Male 4/13/2012 Pharmacist Australia
Primary
Concomitant
Unevaluable Event Hospitalization Male 4/16/2012 Consumer United States
Primary
Secondary
Catatonia Hospitalization Male 4/16/2012 Consumer United States
Primary
Secondary
Anaemia Other Serious 1/1/2011 60 Male 4/19/2012 Physician Ireland
Primary
Concomitant
Schizophrenia Other Serious 4/2/2012 34 Male 4/23/2012 Consumer United States
Primary
Secondary
Speech Disorder Hospitalization Male 4/24/2012 Physician United States
Primary
Concomitant
Swelling Face Other Serious Female 5/2/2012 Consumer United States
Primary
Secondary
Depressed Mood Other Serious Female 5/2/2012 Consumer United States
Primary
Secondary
Splenomegaly Other Serious 1/1/2003 29 Male 170 lb 5/8/2012 Physician Australia
Primary
Secondary
Concomitant
Insomnia Hospitalization 6/1/2011 Male 5/7/2012 Consumer United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 5/4/2012 78 Female 5/10/2012 Pharmacist Australia
Primary
Secondary
White Blood Cell Count Decreased Other Serious 5/4/2012 78 Female 5/10/2012 Pharmacist Australia
Primary
Secondary

Drug Data