Clopidogrel combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 10/2/2005 Male 1/23/2006 Other Health Professional
Primary
Concomitant
Sudden Cardiac Death Death 7/10/2005 Female 157 lb 1/24/2006 Other Health Professional
Primary
Concomitant
Platelet Count Decreased Life Threatening 10/10/2005 Female 10/18/2005 United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 11/29/2005 61 Female 92 lb 1/23/2006 Pharmacist United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Life Threatening 10/2/2004 Female 187 lb 3/23/2006 Other Health Professional Australia
Primary
Concomitant
Pharyngeal Oedema Other Serious 5/27/2005 59 Male 3/27/2006 Consumer Spain
Primary
Concomitant
Respiratory Failure Life Threatening 6/3/2005 63 Male 218 lb 3/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 10/15/2003 45 Male 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 10/2/2005 Male 5/3/2006 Other Health Professional
Primary
Concomitant
Rash Maculo-papular Required Intervention 9/24/2005 76 Female 159 lb United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 5/14/2006 154 lb 6/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Panic Attack Hospitalization 9/3/2006 63 Male 258 lb 10/5/2006 Germany
Primary
Concomitant
Ventricular Fibrillation Other Serious 70 Male 12/29/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 6/6/2006 58 Male 212 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/25/2006 69 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 10/3/2006 70 Male 3/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombolysis Death 10/3/2006 70 Male 132 lb 3/15/2007 United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Rupture Other Serious 2/22/2007 70 Male 176 lb 4/17/2007
Primary
Secondary
Concomitant
Left Ventricular Failure Other Serious 5/14/2006 80 Female 154 lb 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intestinal Obstruction Other Serious 7/15/2007 65 Female 8/6/2007 Pharmacist United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/11/2004 52 Male 7/31/2007 Canada
Primary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/5/2007 United States
Primary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/11/2007 United States
Primary
Concomitant
Death Death 5/23/2007 Male 183 lb 11/2/2007 United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram St Segment Elevation Other Serious 12/14/2007 49 Female 194 lb 12/27/2007 Pharmacist United States
Primary
Concomitant
Death Death 5/23/2007 Male 183 lb 2/5/2008 United States
Primary
Concomitant
Angina Pectoris Hospitalization 3/21/2007 72 Male 2/8/2008 Physician United States
Primary
Concomitant
Circulatory Collapse Hospitalization 1/16/2008 73 Male 2/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 1/16/2008 73 Male 2/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 7/22/2005 65 Male 176 lb 3/1/2008 United Kingdom
Primary
Concomitant
Hypotension Other Serious 8/22/2007 62 Male 201 lb 3/10/2008 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 65 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 65 Male 3/13/2008 United Kingdom
Primary
Secondary
Concomitant
Mental Status Changes Required Intervention 2/17/2008 80 Female 141 lb 2/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Therapy Cessation Hospitalization 62 Female 110 lb 4/15/2008 Physician France
Primary
Concomitant
Death Death 5/23/2007 Male 183 lb 6/18/2008 United States
Primary
Concomitant
Overdose Other Serious 1/1/2006 Female 6/30/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 7/22/2008 65 Male 176 lb 8/13/2008 United Kingdom
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 9/29/2007 9/2/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 9/29/2007 9/4/2008 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 8/26/2008 Male 152 lb 8/29/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 Female 134 lb 9/19/2008 Physician United States
Primary
Concomitant
Tremor Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 11/26/2008 Physician United States
Primary
Concomitant
Liver Disorder Other Serious 44 Female 12/23/2008 Pharmacist United States
Primary
Concomitant
Nausea Other Serious 44 Female 1/26/2009
Primary
Secondary
Liver Disorder Other Serious 44 Female 1/22/2009 Pharmacist United States
Primary
Concomitant
Nausea Other Serious 44 Female 1/27/2009 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Hospitalization 44 Female 2/6/2009 Consumer United States
Primary
Concomitant
Liver Injury Other Serious 44 Female 2/5/2009 Pharmacist United States
Primary
Concomitant
Cardiac Failure Death 10/10/2008 Male 176 lb 3/4/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/12/2003 60 Male 216 lb 4/3/2009 United States
Primary
Concomitant
Syncope Hospitalization 1/16/2008 73 Male 4/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/23/2009 45 Male 5/21/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/23/2005 Male 7/7/2009 Consumer Germany
Primary
Secondary
Concomitant
Pericarditis Other Serious 7/13/2009 Physician Denmark
Primary
Concomitant
Stomatitis Hospitalization 4/7/2008 69 Female 109 lb 7/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Obstructive Airways Disorder Other Serious 70 Male 7/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Obstructive Airways Disorder Other Serious 70 Male 7/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Injection Site Haematoma Other Serious Female 8/25/2009 Physician Denmark
Primary
Concomitant
Death Death Male 8/25/2009 Physician Denmark
Primary
Concomitant
Death Death Male 8/25/2009 Physician Denmark
Primary
Concomitant
Unevaluable Event Other Serious 8/25/2009 Physician Denmark
Primary
Concomitant
Death Death Male 8/25/2009 Physician Denmark
Primary
Concomitant
Death Death Male 8/25/2009 Physician Denmark
Primary
Concomitant
Death Death Male 8/25/2009 Physician Denmark
Primary
Concomitant
Death Death Male 8/25/2009 Physician Denmark
Primary
Concomitant
Death Death Male 8/25/2009 Physician Denmark
Primary
Concomitant
Off Label Use Death Female 8/25/2009 Physician Denmark
Primary
Concomitant
Serotonin Syndrome Hospitalization 65 Male 8/26/2009 United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 8/5/2009 53 Female 287 lb 9/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Required Intervention 7/10/2009 32 Female 158 lb 7/28/2009 Pharmacist United States
Primary
Concomitant
Tremor Required Intervention 7/21/2009 65 7/22/2009 United States
Primary
Secondary
Concomitant
Lethargy Required Intervention 11/16/2008 55 Male 217 lb 11/19/2008 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Rupture Death 6/10/2009 Male 132 lb 9/29/2009 Other Health Professional Japan
Primary
Concomitant
Fluid Overload Other Serious 10/8/2009 62 Female 187 lb 10/15/2009 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 74 Female 164 lb 11/17/2009 United States
Primary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 12/1/2009 Physician United States
Primary
Concomitant
Fluid Overload Other Serious 10/8/2009 12/11/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 74 Female 164 lb 12/2/2009 United States
Primary
Concomitant
Wound Infection Other Serious 8/24/2007 Female 157 lb 12/17/2009 Pharmacist United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 10/22/2009 65 Male 116 lb 11/17/2009 Pharmacist United States
Primary
Concomitant
Suicide Attempt Life Threatening 12/26/2009 60 Male 1/13/2010 Physician Denmark
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/7/2008 69 Female 109 lb 1/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Life Threatening 65 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 65 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 65 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 74 Female 164 lb 1/8/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 74 Female 164 lb 1/20/2010 United States
Primary
Concomitant
Suicide Attempt Life Threatening 12/26/2009 60 Male 2/10/2010 Physician Denmark
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12/1/2007 66 Male 3/9/2010 Lawyer United States
Primary
Concomitant
Somnolence Other Serious 1/16/2010 49 Female 22 lb 1/18/2010 Pharmacist United States
Primary
Concomitant
Weaning Failure Other Serious 12/1/2007 66 Male 4/13/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 44 Male 179 lb 5/3/2010 Lawyer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 5/10/2010 84 Female 113 lb 5/14/2010 Pharmacist United States
Primary
Concomitant
Weaning Failure Other Serious 12/1/2007 66 Male 6/14/2010 Lawyer United States
Primary
Concomitant
Rash 2/4/2008 52 Male 159 lb 6/15/2010 Lawyer United States
Primary
Concomitant
Urticaria Other Serious 5/24/2010 57 Male 6/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Other Serious 5/24/2010 57 Male 6/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Peripheral Vascular Disorder Hospitalization 10/17/2009 59 Male 171 lb 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Other Serious 5/24/2010 57 Male 6/18/2010 Other Health Professional
Primary
Concomitant
Vomiting Other Serious 2/1/2008 44 Male 179 lb 7/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Pruritic 1/31/2008 52 Male 159 lb 8/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/1/2009 8/18/2010 Physician France
Primary
Concomitant
Chronic Myelomonocytic Leukaemia Other Serious 8/11/2010 8/31/2010 Sweden
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Chronic Myelomonocytic Leukaemia Other Serious 8/11/2010 81 Male 9/21/2010 Sweden
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 49 Male 10/8/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Weaning Failure Other Serious 12/1/2007 66 Male 10/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 10/1/2010 73 Male 207 lb 10/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Staphylococcal Other Serious 1/1/2008 0 Male 4 lb 11/10/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/1/2010 73 Male 207 lb 11/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Other Serious 9/1/2010 59 Male 143 lb 12/23/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Vomiting Other Serious 2/1/2008 44 Male 179 lb 12/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myoclonus Other Serious 11/2/2009 68 Male 12/30/2010 Pharmacist United States
Primary
Concomitant
Sepsis Life Threatening 10/1/2010 73 Male 207 lb 2/23/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash Erythematous 1/31/2008 52 Male 159 lb 3/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Other Serious 8/29/2010 59 Male 143 lb 3/21/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Angina Unstable Life Threatening 8/29/2010 59 Male 143 lb 3/30/2011 Physician United States
Primary
Concomitant
Interacting
Sudden Death Hospitalization 8/29/2010 59 Male 143 lb 3/30/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Agitation Other Serious 62 Male 194 lb 4/27/2011 Pharmacist Canada
Primary
Concomitant
Peritoneal Haemorrhage Hospitalization 3/25/2011 59 Female 160 lb 6/10/2011 Physician United States
Primary
Secondary
Concomitant
Fall Other Serious 11/1/2010 64 Male 223 lb 6/15/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Groin Infection Disability 3/7/2011 58 Female 160 lb 6/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Peritoneal Haemorrhage Hospitalization 3/25/2011 59 Female 160 lb 6/22/2011 Physician United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Hospitalization 49 Female 6/17/2011 Consumer United States
Primary
Concomitant
Haemorrhage Intracranial Other Serious 5/3/2011 78 Male 225 lb 6/28/2011 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 5/3/2011 78 Male 225 lb 6/29/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Atrial Fibrillation Life Threatening 70 Female 7/1/2011 Netherlands
Primary
Concomitant
Pulmonary Oedema Death 8/17/2011 83 Male 8/29/2011 Physician Austria
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 6/13/2011 73 Female 8/26/2011 Physician United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 8/17/2011 83 Male 9/2/2011 Physician Austria
Primary
Secondary
Concomitant
Haematochezia Hospitalization 11/22/2010 72 Female 124 lb 9/1/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Pleural Effusion Hospitalization 11/22/2010 72 Female 124 lb 9/16/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Haemorrhage Intracranial Other Serious 5/3/2011 78 Male 225 lb 10/7/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Groin Infection Other Serious 3/7/2011 58 Female 160 lb 9/29/2011 Physician United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Disability 8/29/2010 59 Male 143 lb 9/28/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Depression Hospitalization 56 Male 300 lb 11/23/2011 Lawyer United States
Primary
Concomitant

Drug Data