Clopidogrel combined with Metoprolol

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Other Serious 11/26/2005 66 Female 128 lb 12/30/2005 Switzerland
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 3/9/2005 65 Male 137 lb 1/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 10/28/2005 61 Female 187 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/4/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/4/2004 44 Female 160 lb 1/5/2006 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/26/2005 78 Female 198 lb 1/9/2006 Czech Republic
Primary
Secondary
Concomitant
Myalgia Hospitalization 10/28/2005 61 Female 187 lb 1/12/2006 Denmark
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/12/2006 Netherlands
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Life Threatening 2/16/2004 66 Male 1/19/2006 Consumer Poland
Primary
Concomitant
Haemothorax Life Threatening 8/17/2004 77 Male 1/20/2006 Consumer Poland
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 6/29/2005 Male 132 lb 1/20/2006 Physician Germany
Primary
Secondary
Concomitant
Coronary Artery Thrombosis Other Serious 8/10/2004 50 Male 1/25/2006 Physician Brazil
Primary
Concomitant
Platelet Count Decreased Life Threatening 10/10/2005 Female 10/18/2005 United States
Primary
Concomitant
Thrombosis Hospitalization 9/16/2005 Female 9/22/2005 United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 8/30/2004 52 Female 183 lb 1/24/2006 Germany
Primary
Secondary
Concomitant
Haematocrit Decreased Hospitalization 12/28/2005 62 Male 2/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/27/2005 87 Male 127 lb 12/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Vessel Puncture Site Haemorrhage Life Threatening 8/30/2004 52 Female 183 lb 2/7/2006 Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 8/19/2005 65 Male 212 lb 2/7/2006 Denmark
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 10/17/2005 72 Male 208 lb 12/2/2005 Pharmacist United States
Primary
Secondary
Concomitant
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Insomnia 10/1/2005 83 Male 155 lb 1/5/2006 Consumer United States
Primary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 2/17/2006 Poland
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 2/24/2006 Netherlands
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Rash Hospitalization 7/19/2005 Male 271 lb 3/6/2006 Physician New Zealand
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 11/4/2005 75 Male 161 lb 3/2/2006 Other Health Professional Japan
Primary
Concomitant
Drug Ineffective Life Threatening 4/6/2004 77 Male 163 lb 3/14/2006 Consumer Spain
Primary
Concomitant
Thrombosis Other Serious 6/17/2003 48 Male 238 lb 3/14/2006 Consumer Australia
Primary
Concomitant
Catheter Related Complication Other Serious 2/18/2004 71 Male 231 lb 3/14/2006 Consumer Poland
Primary
Concomitant
Retinal Artery Embolism Other Serious 8/5/2004 48 Male 187 lb 3/14/2006 Consumer Poland
Primary
Concomitant
Drug Ineffective Other Serious 2/9/2004 62 Male 229 lb 3/14/2006 Consumer Germany
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 3/8/2006 Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/19/2005 93 Male 3/16/2006 Physician Brazil
Primary
Secondary
Concomitant
Coronary Artery Stenosis Other Serious 1/12/2006 60 Male 205 lb 3/15/2006 Netherlands
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/3/2005 63 Male 218 lb 3/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 3/9/2005 65 Male 137 lb 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 6/14/2005 67 Female 243 lb 4/12/2006 United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 3/5/2006 Male 4/3/2006 Pharmacist United States
Primary
Concomitant
Respiratory Distress Other Serious 2/19/2006 54 Male 4/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Subcutaneous Haematoma Hospitalization 1/24/2006 84 Female 4/24/2006 Poland
Primary
Secondary
Concomitant
Septic Shock Other Serious 86 Female 4/18/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 4/19/2006 Male 148 lb 6/14/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Intracardiac Thrombus Hospitalization 4/28/2006 52 Male 181 lb 7/18/2006 United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 4/17/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 4/1/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 4/27/2006 72 Male 177 lb 5/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 7/21/2006 Poland
Primary
Secondary
Concomitant
Vitreous Haemorrhage Required Intervention 2/9/2003 84 Male 8/8/2006 Denmark
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 47 Male 198 lb 8/29/2006 Romania
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 7/25/2006 52 Male 198 lb 8/29/2006 Romania
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 8/20/2006 85 Male 141 lb 9/8/2006 United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 8/7/2006 43 Male 210 lb 9/13/2006 United States
Primary
Secondary
Concomitant
Intracardiac Thrombus Hospitalization 4/28/2006 52 Male 181 lb 9/13/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 4/19/2006 79 Male 148 lb 9/18/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/3/2006 68 Male 225 lb 9/18/2006 Physician Germany
Primary
Concomitant
Occult Blood Positive Required Intervention 1/14/2006 74 Female 109 lb 6/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Delirium Hospitalization 66 Male 9/26/2006 Physician Switzerland
Primary
Concomitant
Stent Placement Other Serious 4/26/2006 50 Male 9/30/2006 Consumer United States
Primary
Secondary
White Blood Cell Count Increased Life Threatening 4/19/2006 79 Male 148 lb 10/9/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/20/2006 85 Male 141 lb 10/10/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/22/2006 70 Female 143 lb 10/9/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 5/17/2006 50 Female 176 lb 10/11/2006 United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 4/13/2006 53 Male 167 lb 10/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/19/2006 62 Female 11/8/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious Male 11/23/2006 Physician Germany
Primary
Concomitant
Platelet Count Increased Hospitalization 11/4/2006 Female 125 lb 11/27/2006 Other Health Professional
Primary
Concomitant
Presyncope Hospitalization 9/8/2006 Male 209 lb 11/4/2006 Pharmacist United States
Primary
Concomitant
Epistaxis Hospitalization 8/31/2006 84 Male 1/10/2007 United Kingdom
Primary
Secondary
Concomitant
Wound Necrosis Hospitalization 5/17/2006 50 Female 176 lb 1/25/2007 United States
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 9/5/2007 70 Male 223 lb 9/13/2007 Physician Canada
Primary
Concomitant
Pancreatitis Acute Life Threatening 7/1/2007 67 Male 10/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hepatitis Acute Hospitalization 6/21/2007 44 Male 10/2/2007 Physician Australia
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 2/15/2007 50 Female 10/16/2007 Consumer United States
Primary
Concomitant
Arteriovenous Fistula Hospitalization 12/7/2006 Male 234 lb 11/2/2007 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 10/23/2007 Male 154 lb 11/26/2007 Germany
Primary
Concomitant
Pancreatitis Acute Life Threatening 7/1/2007 67 Male 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 10/23/2007 Male 154 lb 12/5/2007 Germany
Primary
Concomitant
Thrombocytopenia Disability 8/5/2007 68 Female 234 lb 12/4/2007 Pharmacist United States
Primary
Concomitant
Injection Site Pruritus Female 12/14/2007 United States
Primary
Concomitant
Underdose 1/1/2004 Male 241 lb 12/15/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/27/2007 81 Male 12/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Melaena Hospitalization 3/3/2008 67 Male 4/16/2008 Physician Switzerland
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 11/3/2007 Male 209 lb 6/11/2008 Physician Australia
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 9/3/2007 6/12/2008 Consumer Canada
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/12/2008
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Mood Altered 3/1/2008 Male 180 lb 6/12/2008 United States
Primary
Concomitant
Swelling Other Serious 1/1/2007 Female 155 lb 6/12/2008 Consumer United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/17/2008
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/11/2008 Other Health Professional United States
Primary
Secondary
Nausea Hospitalization 86 Male 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stent Placement Hospitalization 79 Male 6/25/2008 Consumer United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 Male 6/27/2008 Netherlands
Primary
Concomitant
Retroperitoneal Fibrosis Hospitalization 11/1/2004 Female 172 lb 8/15/2008 Belgium
Primary
Concomitant
Wound Infection Other Serious 1/1/2006 Female 9/30/2008 United States
Primary
Concomitant
Chest Pain Hospitalization 11/28/2008 Male 12/12/2008 United States
Primary
Concomitant
Psoriasis 6/1/2008 Male 215 lb 12/12/2008 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/2/2008 Female 12/16/2008 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2007 50 Male 12/19/2008 Physician United States
Primary
Secondary
Product Quality Issue 9/14/2008 58 Male 12/19/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Death 6/25/2008 Female 12/23/2008 Physician New Zealand
Primary
Secondary
Concomitant
Platelet Count Decreased Death 3/18/2008 Male 190 lb 12/24/2008 Other Health Professional Turkey
Primary
Concomitant
Rash Hospitalization 11/26/2008 56 Male 12/26/2008 Physician Switzerland
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2007 69 Male 12/24/2008 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2007 50 Male 12/24/2008 Physician
Primary
Secondary
Completed Suicide Death 50 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 50 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 69 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Acute Coronary Syndrome Other Serious 11/3/2008 38 Male 12/31/2008 Physician Germany
Primary
Concomitant
Hypotension Hospitalization 9/13/2008 82 Female 170 lb 1/7/2009 United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Death 50 Male 1/7/2009 Physician United States
Primary
Secondary
Acute Coronary Syndrome Other Serious 11/3/2008 38 Male 1/13/2009 Physician Germany
Primary
Concomitant
Poisoning Death 69 Male 1/19/2009 Physician United States
Primary
Secondary
Drug Abuse Death 69 Male 1/26/2009
Primary
Secondary
Completed Suicide Death 1/29/2009 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 69 Male 1/30/2009 Other Health Professional United States
Primary
Secondary
Pyrexia Other Serious 53 Female 2/10/2009 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Female 2/24/2009 United States
Primary
Concomitant
Pruritus Male 2/24/2009 United States
Primary
Concomitant
Tremor 12/1/2008 Male 2/24/2009 United States
Primary
Concomitant
Diarrhoea Male 2/24/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 80 Male 2/26/2009 Other Health Professional China
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/9/2009 Male 2/26/2009 Physician Switzerland
Primary
Secondary
Concomitant
Vomiting Life Threatening 69 Female 2/23/2009 Physician Italy
Primary
Secondary
Concomitant
Pain Hospitalization 57 Male 256 lb 3/9/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 3/9/2009 Consumer United Kingdom
Primary
Secondary
Respiratory Failure Other Serious 1/1/2008 Male 3/10/2009 Physician Canada
Primary
Concomitant
Multiple Injuries Death 67 Male 3/12/2009 United States
Primary
Concomitant
Vitamin B12 Decreased Life Threatening 12/21/2008 85 Male 121254 lb 3/19/2009 Physician
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 3/23/2009 United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 78 Female 3/26/2009 Other Health Professional United States
Primary
Concomitant
Pericardial Effusion Death 11/11/2008 4/1/2009 Other Health Professional India
Primary
Concomitant
Tobacco User Other Serious 1/1/2007 Female 220 lb 4/1/2009 Consumer
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 1/1/2009 4/2/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 4/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 12/18/2007 Female 153 lb 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 69 Female 229 lb 4/21/2009 Pharmacist United States
Primary
Concomitant
Asthenia Hospitalization 1/11/2009 4/24/2009 Physician Sweden
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 10/16/2008 69 Male 226 lb 1/12/2009 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2006 67 Male 180 lb 5/1/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 4/26/2009 51 Male 271 lb 5/5/2009 Pharmacist United States
Primary
Concomitant
Nephropathy Toxic Other Serious 3/29/2009 52 Female 132 lb 5/13/2009 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Life Threatening 2/1/2009 56 Female 170 lb 5/11/2009 Physician Germany
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/9/2009 Male 5/19/2009 Physician Switzerland
Primary
Secondary
Concomitant
Syncope Hospitalization 2/23/2009 45 Male 5/21/2009 Physician United States
Primary
Concomitant
Myocardial Ischaemia Life Threatening 6/7/2009 71 6/24/2009 Physician India
Primary
Concomitant
Weight Increased Hospitalization 5/1/2002 59 Male 165 lb 7/9/2009 Other Health Professional United States
Primary
Concomitant
Palpitations Hospitalization 6/9/2005 66 Male 227 lb 7/10/2009 Physician Germany
Primary
Concomitant