Clonidine combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Sedation Life Threatening 12/6/2005 44 Female 1/18/2006 Switzerland
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 12/6/2005 44 Female 132 lb 2/3/2006 Physician Switzerland
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 5/17/2006 65 Male 8/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Respiratory Distress Other Serious 5/17/2006 65 Male 1/29/2007 Other Health Professional France
Primary
Secondary
Concomitant
Intestinal Infarction Hospitalization 1/31/2006 Male 170 lb 2/7/2007 Physician
Primary
Concomitant
Drug Ineffective Other Serious 2/20/2007 28 Male 132 lb 3/16/2007 Pharmacist United States
Primary
Concomitant
Oxygen Saturation Decreased Life Threatening 10/24/2005 Male 165 lb 4/5/2007 Physician
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/19/2007 39 Female 450 lb 9/12/2007 Pharmacist United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Drug Effect Decreased Other Serious 58 Female 11/30/2007
Primary
Concomitant
Heart Rate Abnormal Required Intervention 58 Female 11/27/2007 Consumer Australia
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/16/2005 36 Female 2/13/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/16/2005 36 Female 2/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization Female 2/25/2008
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/16/2005 Female 3/4/2008 Consumer
Primary
Secondary
Concomitant
No Adverse Event 44 Female 132 lb 5/7/2008 Physician Switzerland
Primary
Concomitant
Interacting
Haematocrit Decreased Hospitalization 7/20/2007 71 Male 5/20/2008 Other Health Professional United States
Primary
Concomitant
Tachycardia 5/10/2008 25 Female 5/28/2008 Belgium
Primary
Concomitant
Tachycardia Hospitalization 5/10/2008 69 Female 5/28/2008 Belgium
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 3/27/2008 79 Female 165 lb 6/13/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/31/2008 Male 5 lb 6/26/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tachycardia 5/10/2008 25 Female 6/26/2008 Belgium
Primary
Concomitant
Tachycardia Hospitalization 5/10/2008 69 Female 6/26/2008 Belgium
Primary
Concomitant
Pneumonia Death 7/17/2008
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 7/17/2008
Primary
Secondary
Concomitant
Wound Infection Other Serious 7/17/2008
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/17/2008
Primary
Secondary
Concomitant
Demyelination Hospitalization 7/17/2008
Primary
Secondary
Concomitant
Urinary Retention Other Serious 7/17/2008
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/17/2008
Primary
Secondary
Concomitant
Tachycardia 5/10/2008 25 Female 7/16/2008 Physician Belgium
Primary
Concomitant
Drug Ineffective Hospitalization 38 Male 8/7/2008
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 3/27/2008 79 Female 167 lb 10/10/2008 Pharmacist United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 44 Female 11/12/2008 Other Health Professional Australia
Primary
Concomitant
Somnolence Other Serious 61 Female 143 lb 1/8/2009 Other Health Professional Brazil
Primary
Concomitant
Haemorrhage Hospitalization 2/18/2009
Primary
Secondary
Concomitant
Wound Infection Hospitalization 2/18/2009
Primary
Secondary
Concomitant
Tachycardia Life Threatening 61 Female 143 lb 4/6/2009
Primary
Secondary
Concomitant
Weight Fluctuation Other Serious 1/1/2004 20 Male 160 lb 4/14/2009 United States
Primary
Concomitant
Rash Life Threatening 4/7/2009 62 Female 148 lb 4/13/2009 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/23/2005 Male 7/7/2009 Consumer Germany
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Hospitalization 6/4/2009 79 Female 143 lb 7/1/2009 Pharmacist United States
Primary
Concomitant
Tongue Oedema Hospitalization 50 Female 7/16/2009 Pharmacist United States
Primary
Concomitant
Sedation Other Serious 0 Male 11 lb 10/7/2009
Primary
Secondary
Concomitant
Neuromuscular Block Prolonged Hospitalization 10/20/2009
Primary
Secondary
Concomitant
Pyrexia Hospitalization 50 Female 10/31/2009 Pharmacist United States
Primary
Concomitant
Sedation Hospitalization 10 Male 11 lb 12/28/2009 Physician India
Primary
Concomitant
Hepatic Enzyme Abnormal Other Serious 12/27/2009 38 Female 165 lb 1/5/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious 1/6/2010
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 71 Female 2/3/2010 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 50 Female 1/29/2010 Pharmacist United States
Primary
Concomitant
Blood Pressure Decreased Life Threatening 2/5/2010 Male 146 lb 2/24/2010 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 2/26/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2010 Female 2/26/2010 Pharmacist United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 71 Male 3/3/2010 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 71 Male 3/24/2010 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/21/2009 45 Male 5/12/2010 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/10/2009 54 Male 5/17/2010 Physician Germany
Primary
Secondary
Concomitant
Drug Dependence Hospitalization 36 5/20/2010 Physician United States
Primary
Secondary
Pneumonia Aspiration Hospitalization 33 Male 5/20/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 35 Male 5/20/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pneumonia Hospitalization 33 Male 5/20/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 36 5/20/2010 Physician United States
Primary
Secondary
Pulmonary Oedema Hospitalization 36 5/20/2010 Physician United States
Primary
Secondary
Vascular Graft Hospitalization 6/10/2009 54 Male 5/21/2010 Physician
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 5/19/2010 73 Male 198 lb 6/1/2010 Pharmacist Ireland
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 73 Male 6/10/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 4/1/2008 31 Female 284 lb 6/18/2010 Lawyer United States
Primary
Concomitant
Penile Vascular Disorder Other Serious 4 Male 33 lb 6/24/2010
Primary
Secondary
Penile Vascular Disorder Other Serious 4 Male 33 lb 7/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Hypotension Other Serious 1/3/2008 76 Male 7/7/2010 Other Health Professional United States
Primary
Concomitant
Ischaemia Other Serious 4 Male 33 lb 7/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Penile Vascular Disorder Hospitalization 4 Male 33 lb 7/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Somnolence Other Serious 6/1/2010 69 Female 100 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Procedural Complication Other Serious 4 Male 7/9/2010 United Kingdom
Primary
Concomitant
Hypotension Other Serious 7/14/2008 34 Female 7/28/2010 Other Health Professional United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 72 Male 8/5/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/1/2008 31 Female 284 lb 8/17/2010 Other Health Professional United States
Primary
Concomitant
Urosepsis Other Serious 1/1/2007 76 Male 8/26/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2008 71 Female 9/20/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Septic Shock Hospitalization 48 Male 110 lb 10/6/2010
Primary
Secondary
Concomitant
Urosepsis Other Serious 1/1/2007 76 Male 10/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Other Serious 1/1/2007 76 Male 12/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Circulatory Collapse Other Serious 7/1/2008 34 Female 1/7/2011 Lawyer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 1/26/2011 Physician Germany
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 4/1/2008 31 Female 284 lb 2/3/2011 Lawyer United States
Primary
Concomitant
Delayed Recovery From Anaesthesia Other Serious Male 2/15/2011 Other Health Professional Iran (Islamic Republic Of)
Primary
Secondary
Concomitant
Anxiety Death 10/8/2004 45 Female 110 lb 3/10/2011 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 10/8/2004 45 Female 110 lb 3/10/2011 Consumer United States
Primary
Concomitant
Fear Other Serious 12/5/2006 74 Female 225 lb 3/14/2011 Other Health Professional United States
Primary
Concomitant
Asthma Other Serious 4/1/2008 31 Female 284 lb 3/23/2011 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 9/30/2005 82 Female 120 lb 3/29/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Hospitalization 9/30/2005 82 Female 120 lb 3/29/2011 Consumer United States
Primary
Concomitant
Anhedonia Other Serious 10/29/2004 74 Female 150 lb 4/15/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 1/1/2003 76 Female 160 lb 4/19/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 1/1/1980 69 Male 266 lb 4/25/2011 Consumer United States
Primary
Concomitant
Fear Other Serious 7/28/2001 61 Male 161 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Emotional Distress Other Serious 52 Male 275 lb 5/4/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 9/11/2005 62 Male 280 lb 5/11/2011 Other Health Professional United States
Primary
Concomitant
Renal Injury Other Serious Male 214 lb 5/14/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 9/11/2005 62 Male 280 lb 5/17/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Death 2/27/2005 76 Female 160 lb 5/19/2011 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 8/29/2008 53 Male 154 lb 5/24/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Other Serious 5/26/2006 Male 251 lb 5/26/2011 Other Health Professional United States
Primary
Concomitant
Peritonitis Hospitalization 1/1/2005 66 Male 5/27/2011 Other Health Professional Germany
Primary
Interacting
Dystonia Other Serious 7/1/2009 58 Female 175 lb 5/23/2011 Lawyer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 6/22/2005 66 Male 5/26/2011 Consumer
Primary
Secondary
Apnoea Hospitalization 54 Female 344 lb 6/7/2011 Other Health Professional United States
Primary
Concomitant
Renal Injury Other Serious 2/10/2005 83 Male 194 lb 6/10/2011 Other Health Professional United States
Primary
Concomitant
Hypertension Hospitalization Female 6/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Injury Death 2/19/2007 80 Male 180 lb 6/29/2011 Lawyer United States
Primary
Concomitant
Depression Other Serious 6/24/2006 43 Male 7/11/2011 Physician United States
Primary
Concomitant
Dehydration Hospitalization 7/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tongue Paralysis Other Serious 7/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Convulsion Disability 6/30/2011 62 Male 269 lb 7/8/2011 Pharmacist United States
Primary
Concomitant
Unevaluable Event Hospitalization 1/1/2003 76 Female 160 lb 7/20/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Other Serious 11/11/2004 79 Male 194 lb 7/20/2011 Other Health Professional United States
Primary
Concomitant
Disorientation Hospitalization 1/1/2005 66 Male 7/22/2011 Other Health Professional Germany
Primary
Interacting
Cardiac Failure Other Serious 7/30/2010 71 Male 176 lb 7/22/2011 Physician Germany
Primary
Concomitant
Fear Hospitalization 4/14/2007 61 Male 135 lb 7/25/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 11/25/2002 74 Female 150 lb 7/28/2011 Physician United States
Primary
Concomitant
Renal Injury Other Serious 1/1/2003 76 Female 160 lb 8/8/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious Male 276 lb 8/17/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Death 8/29/2008 53 Male 154 lb 8/18/2011 Lawyer United States
Primary
Concomitant
Exposed Bone In Jaw Other Serious Male 240 lb 8/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 38 Male 8/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Anhedonia Other Serious 3/1/2004 56 Male 154 lb 9/6/2011 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 38 Male 9/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Electrocardiogram Qt Prolonged Other Serious 38 Male 9/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 1/7/2011 36 Male 198 lb 9/29/2011 Physician Germany
Primary
Secondary
Concomitant
Interacting
Urethral Stenosis Hospitalization Male 240 lb 10/10/2011 Lawyer United States
Primary
Secondary
Concomitant
Cholelithiasis Other Serious Male 240 lb 10/13/2011 Lawyer United States
Primary
Secondary
Concomitant
Death Other Serious 3/1/2004 56 Male 154 lb 10/20/2011 Consumer United States
Primary
Concomitant
Nephrolithiasis Other Serious Male 240 lb 10/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Other Serious 11/11/2004 79 Male 194 lb 10/25/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious Male 240 lb 11/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 5/7/1996 61 Male 185 lb 11/25/2011 Consumer Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 5/7/1996 61 Male 185 lb 11/25/2011 Consumer Germany
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Oedema Peripheral Death Male 240 lb 12/19/2011 Lawyer United States
Primary
Secondary
Concomitant
Soft Tissue Mass Other Serious Male 240 lb 1/5/2012 Physician United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious Male 240 lb 1/24/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data