Clonidine combined with Optimark

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Nephrogenic Systemic Fibrosis Other Serious 1/1/2007 12/17/2007 Other Health Professional United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 6/22/2007 6/20/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 6/22/2007 7/1/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Disability 9/12/2007 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Death 5/5/2005 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 11/9/2007 7/31/2008 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Death 4/1/2006 7/31/2008 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 4/12/2006 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Toe Amputation Other Serious 6/22/2007 8/14/2008 Physician Germany
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 11/9/2007 8/15/2008 Physician United States
Primary
Concomitant
Pain Other Serious 6/22/2007 Male 10/29/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Death 4/1/2006 3/17/2009 Physician United States
Primary
Concomitant
Venous Insufficiency Other Serious 6/11/2006 43 Male 3/23/2009 United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Death 2/1/2007 Female 4/7/2009 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 11/17/2006 Female 4/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Death 4/1/2006 5/4/2009 Physician United States
Primary
Concomitant
Toe Amputation Other Serious 6/22/2007 5/7/2009 Physician Germany
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 11/17/2006 Female 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 3/14/2005 7/8/2009 Physician United States
Primary
Concomitant
Oedema Peripheral Death 10/7/2007 Female 7/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 3/24/2005 Female 7/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 4/30/2007 46 Male 161 lb 7/10/2009 Lawyer United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 4/1/2006 7/13/2009 Physician United States
Primary
Concomitant
Off Label Use Other Serious 3/14/2005 7/13/2009 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 2/1/2007 Female 7/14/2009 Physician United States
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 6/18/2007 41 Female 159 lb 7/15/2009 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 4/30/2007 46 Male 161 lb 7/20/2009 Lawyer United States
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 6/18/2007 41 Female 159 lb 7/20/2009 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 12/2/2005 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/26/2003 Female 7/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 9/12/2007 7/28/2009 Consumer United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 3/14/2005 7/28/2009 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 2/1/2004 7/30/2009 Physician United States
Primary
Concomitant
Periorbital Cellulitis Other Serious 3/24/2005 Female 184 lb 8/2/2009 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2006 8/2/2009 Physician United States
Primary
Concomitant
Tremor Other Serious 3/14/2007 8/14/2009 Physician Germany
Primary
Secondary
Concomitant
Oedema Peripheral Death 10/7/2007 Female 8/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2006 8/17/2009 Physician United States
Primary
Concomitant
Oedema Peripheral Death 10/7/2007 Female 179 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 3/14/2007 9/18/2009 Physician Germany
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/28/2004 10/6/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/29/2006 Female 138 lb 10/8/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2006 10/9/2009 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 6/7/2007 Female 116 lb 10/22/2009 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 3/14/2007 11/25/2009 Physician Germany
Primary
Secondary
Concomitant
Tremor Other Serious 3/14/2007 12/1/2009 Physician Germany
Primary
Secondary
Concomitant
Tremor Other Serious 3/14/2007 12/2/2009 Physician Germany
Primary
Secondary
Concomitant
Off Label Use Other Serious 7/27/2006 12/17/2009 Consumer United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 11/8/2005 12/17/2009 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 8/1/2006 46 Male 161 lb 1/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 3/7/2001 51 Male 2/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 11/8/2005 2/19/2010 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/29/2006 Female 152 lb 3/17/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 7/10/2004 Female 179 lb 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 3/9/2005 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Xerosis Other Serious 7/27/2006 3/24/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/29/2006 Female 152 lb 3/26/2010 United States
Primary
Concomitant
Skin Tightness Other Serious 9/1/2006 51 Male 170 lb 5/11/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 9/1/2006 51 Male 170 lb 5/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/24/2005 67 Male 154 lb 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/1/2003 31 Female 5/21/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 9/1/2006 76 Male 176 lb 5/21/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 9/1/2006 51 Male 170 lb 5/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 9/1/2006 76 Male 176 lb 5/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2004 59 Female 269 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2004 59 Female 269 lb 6/10/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/24/2005 67 Male 154 lb 6/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/24/2005 67 Male 154 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2004 59 Female 269 lb 6/23/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/24/2005 67 Male 154 lb 6/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/24/2005 67 Male 154 lb 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2006 50 Male 170 lb 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 8/1/2006 46 Male 161 lb 6/30/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious Female 148 lb 7/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2006 50 Male 170 lb 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 8/1/2006 46 Male 161 lb 7/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 1/1/2005 55 Female 148 lb 7/6/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2004 59 Female 269 lb 7/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/24/2005 67 Male 154 lb 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/24/2005 67 Male 154 lb 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2004 59 Female 269 lb 7/21/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/24/2005 67 Male 154 lb 7/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/28/2004 8/19/2010 Physician United States
Primary
Concomitant
Skin Tightness Other Serious 39 Male 220 lb 9/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 39 Male 220 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/24/2005 67 Male 154 lb 9/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Plaque Death Female 141 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Plaque Death 1/1/2005 52 Female 141 lb 10/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 10/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/10/2004 60 Female 141 lb 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 3/7/2001 51 Male 154 lb 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 9/1/2006 51 Male 174 lb 11/24/2010 Physician United States
Primary
Secondary
Concomitant
Skin Hypertrophy Other Serious 9/1/2006 50 Male 175 lb 1/4/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 3/7/2001 50 Male 154 lb 2/11/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 3/7/2001 50 Male 154 lb 2/11/2011 Consumer United States
Primary
Secondary
Concomitant
Aneurysm Hospitalization 1/1/2006 49 Male 170 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 9/1/2006 50 Male 175 lb 3/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anxiety Death 11/1/2005 34 Male 217 lb 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anhedonia Death 11/1/2005 34 Male 217 lb 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 8/31/2005 40 Female 182 lb 3/14/2011 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 9/1/2006 50 Male 175 lb 3/15/2011 Physician United States
Primary
Secondary
Concomitant
Skin Hypertrophy Disability 10/24/2005 67 Male 153 lb 3/21/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Fissures Disability 1/1/2007 54 Male 110 lb 3/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Joint Stiffness Other Serious 9/1/2006 50 Male 175 lb 3/24/2011 Consumer United States
Primary
Secondary
Concomitant
Rash Papular Other Serious Male 154 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 9/1/2006 50 Male 175 lb 4/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious Male 154 lb 4/4/2011 Physician United States
Primary
Secondary
Concomitant
Burning Sensation Death 11/1/2005 34 Male 217 lb 4/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Face Oedema Other Serious 4/29/2006 56 Female 152 lb 4/12/2011 United States
Primary
Concomitant
Cardiac Murmur Hospitalization 7/10/2004 52 Female 179 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious Male 164 lb 5/2/2011 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious Male 164 lb 5/2/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 11/1/2008 72 Male 184 lb 5/2/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Range Of Motion Decreased Other Serious 3/1/2005 48 Male 5/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Plaque Other Serious 4/1/2004 52 Female 171 lb 5/9/2011 Consumer United States
Primary
Secondary
Concomitant
Injury Other Serious 1/1/2003 70 Female 5/19/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Range Of Motion Decreased Other Serious 3/7/2001 50 Male 154 lb 5/19/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2003 70 Female 5/19/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 3/7/2001 50 Male 154 lb 5/19/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Stiffness Other Serious 9/1/2006 50 Male 175 lb 5/31/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Hypertrophy Other Serious 7/1/2003 69 Male 157 lb 6/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 4/1/2004 52 Female 171 lb 6/4/2011 Consumer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 9/1/2006 50 Male 175 lb 6/7/2011 Physician United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 4/1/2004 52 Female 171 lb 6/7/2011 Consumer United States
Primary
Secondary
Concomitant
Pruritus Other Serious 1/1/2003 31 Female 6/10/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Range Of Motion Decreased Other Serious 3/1/2005 48 Male 6/17/2011 Physician United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 3/1/2008 Female 6/18/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Hypertrophy Death Female 210 lb 6/23/2011 Lawyer United States
Primary
Secondary
Concomitant
Amputation Disability 6/22/2007 66 Male 6/29/2011 Physician United States
Primary
Secondary
Concomitant
Skin Induration Death 1/1/2004 39 Female 117 lb 6/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 4/1/2004 52 Female 171 lb 7/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Skin Plaque Other Serious 4/1/2004 52 Female 171 lb 7/1/2011 Consumer United States
Primary
Secondary
Concomitant
Muscle Contracture Other Serious Female 7/2/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death Female 7/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Disability 2/1/2008 3 Female 174 lb 7/6/2011 Physician United States
Primary
Secondary
Concomitant
Pain Death 6/21/2007 50 Female 155 lb 7/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Other Serious 11/1/2008 72 Male 183 lb 7/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fall Other Serious 22 Male 160 lb 7/12/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Hypertrophy Other Serious 11/1/2008 72 Male 183 lb 7/13/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Range Of Motion Decreased Death 3/7/2001 50 Male 154 lb 7/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Injury Other Serious 3/26/2003 29 Female 188 lb 7/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 1/1/2007 39 Female 174 lb 7/18/2011 Physician United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 1/1/2007 55 Male 110 lb 7/20/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Exfoliation Disability 1/1/2004 38 Male 179 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Calcification Other Serious 22 Male 160 lb 7/22/2011 Consumer United States
Primary
Secondary
Concomitant
Pruritus Other Serious 1/1/2006 67 Male 140 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Other Serious 1/1/2006 48 Female 180 lb 7/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data