Clonidine combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pruritus Hospitalization 11/20/2005 54 Male 194 lb 12/13/2005 Pharmacist United States
Primary
Concomitant
Ventricular Dyskinesia Hospitalization 9/1/2001 71 Male 276 lb 3/28/2006 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 6/4/2004 42 Male 274 lb 3/28/2006 Physician United States
Primary
Concomitant
Nausea 77 Female 235 lb 1/20/2006 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 85 Female 4/7/2006 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 85 Female 4/17/2006 Other Health Professional United States
Primary
Concomitant
Dehydration Hospitalization 4/17/2006 Female 176 lb 4/27/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/15/2006 85 Female 5/1/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 9/1/2001 71 Male 276 lb 5/4/2006 Physician United States
Primary
Concomitant
Spinal Cord Disorder Other Serious 1/1/2001 58 Male 209 lb 5/16/2006 Physician United States
Primary
Concomitant
Subdural Haematoma Death 4/30/2006 34 Male 5/22/2006 United States
Primary
Concomitant
Heart Rate Irregular Other Serious 1/1/2006 63 Male 226 lb 5/30/2006 United States
Primary
Concomitant
Weight Increased Other Serious 50 Male 4/20/2006 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 10/7/2005 54 Female 6/19/2006 Physician United States
Primary
Concomitant
Condition Aggravated 2/1/2006 57 Male 4/17/2006 Consumer United States
Primary
Concomitant
Muscular Weakness 12/29/2005 50 Female 4/17/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Death 4/30/2006 34 Male 205 lb 6/29/2006 United States
Primary
Concomitant
Vomiting Other Serious 74 Female 6/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 75 Male 7/21/2006 Consumer United States
Primary
Concomitant
Weight Increased 60 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Leukopenia Required Intervention 4/10/2006 64 Female 5/22/2006 Consumer United States
Primary
Concomitant
Insomnia 1/1/2006 51 Male 230 lb 7/12/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 71 Female 8/18/2006 Denmark
Primary
Concomitant
Weight Decreased Hospitalization 3/26/2006 65 Female 205 lb 8/31/2006 United States
Primary
Concomitant
Weight Decreased 1/1/2006 64 Male 320 lb 7/19/2006 Consumer United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 10/19/2006 73 Female 161 lb 11/2/2006 Pharmacist United States
Primary
Concomitant
Rash Erythematous Other Serious 10/6/2006 62 Female 198 lb 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Erythematous Disability 10/6/2006 62 Female 198 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Generalised Hospitalization 11/5/2006 58 Female 11/16/2006 Consumer United States
Primary
Concomitant
Swelling Face Hospitalization 1/1/2002 50 Female 12/13/2006 Consumer United States
Primary
Concomitant
Application Site Urticaria 62 Male 12/20/2006 Consumer United States
Primary
Concomitant
Dry Mouth Other Serious 69 Female 180 lb 8/19/2005 United States
Primary
Concomitant
Weight Decreased 7/1/2005 58 Male 311 lb 12/11/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 2/26/2007 50 Male 3/23/2007 Physician United States
Primary
Concomitant
Somnolence 3/1/2007 Female 300 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Hypotension 5/1/2007 72 Female 8/16/2007 Physician United States
Primary
Concomitant
Polyuria 5/7/2007 61 Male 8/16/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 2/16/2006 Female 170 lb 10/22/2007 Consumer United States
Primary
Concomitant
Uterine Leiomyoma Other Serious 9/1/2007 Female 168 lb 10/26/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/16/2006 Female 170 lb 1/11/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 1/1/2008 Female 135 lb 3/15/2008 Consumer United States
Primary
Concomitant
Mood Swings 2/1/2008 32 Female 150 lb 3/26/2008 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 4/28/2008 70 Female 6/13/2008 Physician United States
Primary
Concomitant
Sensory Disturbance Other Serious 5/1/2008 Female 6/20/2008 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 7/2/2008 Male 225 lb 7/11/2008 Pharmacist United States
Primary
Concomitant
Pain 1/1/2006 Female 229 lb 8/22/2008 Physician United States
Primary
Secondary
Concomitant
Convulsion Other Serious 8/30/2008 Female 9/9/2008 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 44 Male 230 lb 10/15/2008 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 36 Male 235 lb 10/23/2008 Lawyer United States
Primary
Concomitant
Convulsion Other Serious 9/3/2008 Female 10/28/2008 Physician United States
Primary
Concomitant
Hypotension 9/1/2008 65 Female 11/14/2008 United States
Primary
Concomitant
Hallucination Hospitalization 1/7/2009 Female 167 lb 1/8/2009 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 45 Male 1/12/2009 Physician United States
Primary
Secondary
Swelling Face Hospitalization 11/4/2008 84 Male 1/9/2009 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 1/7/2009 Female 167 lb 1/12/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/18/2008 Female 193 lb 1/16/2009 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 12/30/2008 Female 2/2/2009 Physician United States
Primary
Concomitant
Sepsis Other Serious 5/12/2007 Male 210 lb 2/20/2009 Physician United States
Primary
Concomitant
Cardiomegaly Hospitalization 1/1/2007 43 Male 271 lb 2/26/2009 Consumer United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 11/18/2008 74 Male 254 lb 2/26/2009 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 44 Male 230 lb 3/25/2009 United States
Primary
Concomitant
Normochromic Normocytic Anaemia Hospitalization 1/9/2009 75 Female 207 lb 5/11/2009 Pharmacist United States
Primary
Concomitant
Cellulitis Hospitalization 4/1/2009 60 Female 6/10/2009 Pharmacist Canada
Primary
Concomitant
Breast Cancer Other Serious 5/19/1999 Female 154 lb 6/16/2009 Lawyer United States
Primary
Secondary
Concomitant
Tremor 1/1/2009 80 Female 6/12/2009 Consumer United States
Primary
Concomitant
Renal Failure Life Threatening 57 Female 6/17/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 45 Male 224 lb 6/25/2009 United States
Primary
Concomitant
Torsade De Pointes Other Serious 72 Female 6/25/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Type 2 Diabetes Mellitus Other Serious 5/8/2007 36 Female 260 lb 6/29/2009 United States
Primary
Concomitant
Vomiting Other Serious 3/18/2009 56 Female 258 lb 7/17/2009 United States
Primary
Concomitant
Weight Increased Life Threatening 57 Female 7/21/2009 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/1999 39 Male 258 lb 7/30/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Vitreous Haemorrhage Death 64 Male 217 lb 7/22/2009 United States
Primary
Concomitant
Vomiting Death 83 Female 8/3/2009 United States
Primary
Concomitant
Weight Increased Life Threatening 57 Female 8/3/2009 United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 12/20/2006 69 Male 179 lb 8/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Surgery Death Female 8/4/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 47 Male 8/18/2009 United States
Primary
Secondary
Concomitant
Thinking Abnormal Other Serious 7/6/2005 51 Male 181 lb 8/20/2009 United States
Primary
Concomitant
Heart Rate Increased 10/3/2008 Female 150 lb 8/22/2009 Consumer United States
Primary
Concomitant
Breast Cancer Other Serious 5/19/1999 Female 154 lb 8/26/2009 Lawyer United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 9/1/2009 Male 223 lb 11/6/2009 Physician United States
Primary
Concomitant
Unemployment Hospitalization 72 Male 11/4/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 69 Female 11/4/2009 United States
Primary
Concomitant
Feeling Hot 9/1/2009 345 lb 11/25/2009 United States
Primary
Concomitant
Hypertension 11/1/2008 75 Female 11/25/2009 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 65 Female 11/17/2009 United States
Primary
Concomitant
Surgery Hospitalization 1/24/2002 45 Male 11/18/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 11/1/2009 Female 152 lb 12/11/2009 United States
Primary
Concomitant
Intervertebral Disc Disorder Other Serious 10/1/2009 Female 212 lb 1/5/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 75 Male 165 lb 1/14/2010 United States
Primary
Concomitant
Rash 1/1/2007 Female 1/15/2010 Consumer United States
Primary
Concomitant
Speech Disorder Other Serious 1/1/2009 59 Female 1/21/2010 Consumer Colombia
Primary
Concomitant
Injection Site Swelling 9/2/2009 Female 246 lb 1/29/2010 United States
Primary
Concomitant
Skin Ulcer Other Serious Female 2/19/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 60 Female 165 lb 2/22/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 2/13/2010 64 Male 4/7/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/1997 57 Female 120 lb 4/29/2010 Consumer United States
Primary
Secondary
Concomitant
Retinal Injury Other Serious 9/28/2007 30 Female 249 lb 5/5/2010 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 57 Female 150 lb 6/1/2010 Physician United States
Primary
Concomitant
Headache Hospitalization 5/24/2010 67 Female 6/2/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 18 Female 245 lb 6/4/2010 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 1/1/2009 65 Female 6/7/2010 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 52 Male 281 lb 6/17/2010 Pharmacist United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 5/1/2007 64 Female 6/17/2010 Other Health Professional United States
Primary
Concomitant
Wound Other Serious 4/28/2008 49 Female 220 lb 7/21/2010 Consumer United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 5/1/2007 64 Female 7/27/2010 Other Health Professional United States
Primary
Concomitant
Rash 2/1/2009 57 Female 198 lb 8/6/2010 Consumer United States
Primary
Concomitant
Haematochezia Other Serious 8/7/2010 69 Female 172 lb 8/17/2010 Consumer United States
Primary
Concomitant
Stress Fracture Hospitalization 1/1/2003 48 Female 258 lb 8/23/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 55 Female 185 lb 8/25/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 52 Female 8/18/2010 United States
Primary
Concomitant
Skin Burning Sensation 8/14/2009 70 Female 8/27/2010 United States
Primary
Concomitant
Pain Male 280 lb 8/28/2010 United States
Primary
Concomitant
Flushing Female 202 lb 8/28/2010 United States
Primary
Concomitant
Nausea Male 228 lb 8/28/2010 United States
Primary
Concomitant
Dizziness 2/12/2010 64 Female 157 lb 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation 4/25/2010 59 Female 147 lb 8/29/2010 Consumer United States
Primary
Concomitant
Dyspepsia 6/22/2010 65 Male 180 lb 8/29/2010 Consumer United States
Primary
Concomitant
Rash Female 236 lb 8/30/2010 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/26/2009 9/7/2010 Other Health Professional Canada
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 8/3/2006 73 Male 9/1/2010 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 57 Female 150 lb 9/16/2010 Physician United States
Primary
Concomitant
Tremor Other Serious 1/1/2001 67 Female 9/17/2010 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/1/2005 67 Female 175 lb 9/17/2010 United States
Primary
Concomitant
Osteonecrosis Other Serious 4/1/2010 59 Male 9/15/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/1/2004 41 Male 315 lb 9/20/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2000 45 Female 204 lb 9/20/2010 United States
Primary
Concomitant
Vision Blurred 8/21/2010 74 Male 185 lb 9/22/2010 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 1/1/2010 49 Male 239 lb 9/23/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization Female 9/23/2010 Physician United States
Primary
Concomitant
Panic Attack Hospitalization 65 Female 193 lb 9/27/2010 Other Health Professional United States
Primary
Concomitant
Nervousness 9/19/2010 51 Female 200 lb 9/26/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 9/19/2010 55 Female 194 lb 9/27/2010 Consumer United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 48 Male 200 lb 9/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nervousness 9/19/2010 51 Female 200 lb 10/4/2010 Consumer United States
Primary
Concomitant
Vision Blurred 8/21/2010 74 Male 185 lb 10/7/2010 Consumer United States
Primary
Concomitant
Proteinuria Other Serious 8/11/2010 55 Female 10/8/2010 Other Health Professional Brazil
Primary
Concomitant
Tremor Other Serious 1/1/2009 58 Female 160 lb 10/11/2010 Consumer United States
Primary
Concomitant
Off Label Use Hospitalization Female 175 lb 10/11/2010 Consumer United States
Primary
Concomitant
Muscular Weakness Other Serious 9/1/2010 73 Female 10/14/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred 8/21/2010 74 Male 185 lb 10/18/2010 Physician United States
Primary
Concomitant
Back Pain 81 Female 159 lb 10/26/2010 Consumer United States
Primary
Concomitant
Muscular Weakness Other Serious 9/3/2010 73 Female 176 lb 10/28/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Disorder 71 Female 10/13/2010 Consumer United States
Primary
Concomitant
Haemolytic Anaemia Hospitalization 6/16/2010 72 Female 176 lb 11/4/2010 Physician France
Primary
Concomitant
Dyspepsia 8/26/2010 42 Female 190 lb 11/16/2010 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 53 Female 220 lb 11/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data