Clonidine combined with Fentanyl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sedation Life Threatening 12/6/2005 44 Female 1/18/2006 Switzerland
Primary
Secondary
Concomitant
Vomiting Other Serious 52 Female 2/7/2006
Primary
Secondary
Drug Toxicity Other Serious 12/6/2005 44 Female 132 lb 2/3/2006 Physician Switzerland
Primary
Secondary
Concomitant
Vomiting Disability 9/14/2005 26 Female 112 lb 1/20/2006 Physician United States
Primary
Concomitant
Fatigue Other Serious 2/6/2006 58 Male 164 lb 2/6/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 49 Male 3/20/2006 United States
Primary
Secondary
Concomitant
Wheezing Required Intervention 2/14/1996 41 Male 3/28/2006 Physician United States
Primary
Concomitant
Urinary Hesitation 1/1/2005 45 Female 1/23/2006 Consumer United States
Primary
Concomitant
Pain 8/1/2005 64 Male 1/23/2006 Consumer United States
Primary
Concomitant
Urinary Hesitation 1/1/2005 45 Female 1/31/2006 Consumer United States
Primary
Concomitant
Pain 8/1/2005 64 Male 1/31/2006 Consumer United States
Primary
Concomitant
Wheezing Required Intervention 2/14/1996 41 Male 4/7/2006 Physician United States
Primary
Concomitant
Wheezing Required Intervention 2/14/1996 41 Male 4/7/2006 Physician United States
Primary
Concomitant
Speech Disorder Other Serious 12/1/2005 56 Female 5/16/2006 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 1/1/2005 70 Female 5/19/2006 Consumer United States
Primary
Concomitant
Pain 8/1/2005 64 Male 4/6/2006 Consumer United States
Primary
Concomitant
Peripheral Coldness 12/1/2005 47 Male 4/6/2006 Other Health Professional United States
Primary
Concomitant
Vasospasm Required Intervention 4/17/2006 45 Female 168 lb 6/6/2006 Physician United States
Primary
Concomitant
Quadriplegia Other Serious 12/1/2005 56 Female 6/8/2006 Physician United States
Primary
Secondary
Concomitant
Angioneurotic Oedema Other Serious 5/29/2006 50 Male 177 lb 6/12/2006 United States
Primary
Concomitant
Neuralgia Other Serious 5/29/2006 50 Male 177 lb 6/29/2006 United States
Primary
Concomitant
Cholestasis Hospitalization 20 Female 6/28/2006 Pharmacist United States
Primary
Concomitant
Sarcoidosis Hospitalization 56 Female 7/31/2006 Consumer Germany
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Required Intervention 4/17/2006 45 Female 168 lb 7/27/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2006 79 Female 8/2/2006 Consumer United States
Primary
Concomitant
Hepatic Enzyme Abnormal Other Serious 6/14/2006 56 Male 162 lb 6/14/2006 Pharmacist United States
Primary
Concomitant
Urinary Retention Other Serious 6/12/2006 56 Male 162 lb 6/12/2006 Pharmacist United States
Primary
Concomitant
Sarcoidosis Disability 7/14/2006 56 Female 9/14/2006 Physician Germany
Primary
Secondary
Concomitant
Sarcoidosis Hospitalization 4/16/2006 56 Female 10/6/2006 Physician Germany
Primary
Secondary
Concomitant
Quadriplegia Other Serious 10/8/2006 59 Male 236 lb 11/10/2006 Pharmacist United States
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Suicide Attempt Life Threatening 12/6/2005 42 Female 12/5/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Road Traffic Accident Other Serious 12/15/2006 Female 159 lb 12/27/2006 Consumer United States
Primary
Concomitant
Self Esteem Decreased 7/1/2006 73 Male 11/10/2006 Consumer United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 1/25/2007 29 Male 2/2/2007 Pharmacist United States
Primary
Concomitant
Intestinal Infarction Hospitalization 1/31/2006 Male 170 lb 2/7/2007 Physician
Primary
Concomitant
Tricuspid Valve Incompetence Required Intervention 4/17/2006 45 Female 168 lb 2/6/2007 Physician United States
Primary
Concomitant
Post Procedural Complication Hospitalization 2/2/2007 80 Female 146 lb 2/7/2007 Pharmacist United States
Primary
Concomitant
Medication Error Other Serious 5 Female 37 lb 2/26/2007 United States
Primary
Concomitant
Interacting
Tremor Hospitalization 1/1/2004 79 Male 4/5/2007
Primary
Concomitant
Emotional Disorder Death Female 3/1/2007 Physician United States
Primary
Concomitant
Procedural Complication Death Female 4/26/2007 Physician United States
Primary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Procedural Complication Hospitalization 11/20/2006 36 Female 264 lb 5/1/2007 Consumer United States
Secondary
Concomitant
Gastrointestinal Motility Disorder Hospitalization 11/20/2006 36 Female 265 lb 5/1/2007 United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 12/23/2005 51 Female 121 lb 5/24/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Death 5/11/2007 52 Female 5/24/2007 Physician United States
Primary
Concomitant
Cancer Pain Death 11/18/2006 48 Female 7/20/2007 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Disability 4/14/2007 68 Male 262 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Drug Tolerance Hospitalization 18 Male 8/27/2007
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 12/23/2005 51 Female 121 lb 9/11/2007 Other Health Professional United States
Primary
Concomitant
Pain Required Intervention Male 6/19/2006 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 4/19/2007 39 Female 450 lb 9/12/2007 Pharmacist United States
Primary
Secondary
Concomitant
Paraesthesia Required Intervention 68 Male 1/22/2007 Other Health Professional United States
Primary
Concomitant
Apgar Score Low Other Serious 9/24/2007
Primary
Secondary
Respiratory Disorder Neonatal Other Serious 9/24/2007
Primary
Secondary
Apgar Score Low Other Serious 9/24/2007
Primary
Secondary
Apgar Score Low Other Serious 9/24/2007
Primary
Secondary
West Nile Viral Infection Other Serious 8/20/2007 Male 100 lb 10/4/2007 Physician Canada
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 1/3/2007 58 Female 112 lb 10/9/2007 Pharmacist United States
Primary
Concomitant
Insomnia 3/1/2007 52 Male 10/25/2007 Consumer United States
Primary
Concomitant
West Nile Viral Infection Other Serious 8/20/2007 Male 100 lb 11/6/2007 Physician Canada
Primary
Secondary
Concomitant
Somnambulism 7/1/2007 45 Female 10/9/2007 Other Health Professional United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Speech Disorder Other Serious 58 Male 12/27/2007
Primary
Secondary
Concomitant
Oculogyric Crisis Other Serious 8 Male 1/2/2008
Primary
Secondary
Pancreatic Carcinoma Death 11/10/2007 58 Male 12/28/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/3/2007 58 Female 112 lb 1/22/2008 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/16/2005 36 Female 2/13/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/16/2005 36 Female 2/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Radiculitis Brachial Hospitalization 65 Male 2/28/2008
Primary
Secondary
Concomitant
Tremor Other Serious 1/28/2008 Male 278 lb 2/22/2008 United States
Primary
Concomitant
Flatulence 5/1/2007 71 Male 1/10/2008 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/16/2005 Female 3/4/2008 Consumer
Primary
Secondary
Concomitant
Convulsion Other Serious 17 Male 3/5/2008
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 3/5/2008
Primary
Secondary
Concomitant
Ureteric Obstruction Other Serious 32 Female 3/7/2008 Physician United States
Primary
Secondary
Neoplasm Malignant Death 5/15/2005 65 Female 2/29/2008 Physician United States
Primary
Concomitant
Urosepsis Death 6/20/2005 54 Female 2/29/2008 Physician United States
Primary
Concomitant
Rash 12/17/2007 Female 303 lb 3/14/2008 United States
Primary
Secondary
Concomitant
Hallucination Other Serious 5 Male 31 lb 3/20/2008
Primary
Concomitant
Convulsion Other Serious 17 Male 3/20/2008
Primary
Secondary
Concomitant
Partial Seizures Other Serious 17 Male 3/20/2008
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 3/20/2008
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 3/20/2008
Primary
Secondary
Concomitant
Low Density Lipoprotein Increased Hospitalization 3/1/2007 50 Female 150 lb 3/7/2008 Physician United States
Primary
Concomitant
Death Death 50 Female 4/29/2008 Physician United States
Primary
Concomitant
No Adverse Event 44 Female 132 lb 5/7/2008 Physician Switzerland
Primary
Concomitant
Interacting
Haematocrit Decreased Hospitalization 7/20/2007 71 Male 5/20/2008 Other Health Professional United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 3/27/2008 79 Female 165 lb 6/13/2008 Pharmacist United States
Primary
Concomitant
Thoracic Haemorrhage Hospitalization 9 Male 79 lb 6/18/2008
Primary
Secondary
Spinal Cord Oedema Disability 9 Male 79 lb 6/17/2008 Physician Netherlands
Primary
Secondary
Concomitant
Viral Infection Death 46 Male 7/1/2008 Physician Canada
Primary
Secondary
Concomitant
Pain Required Intervention 1/1/2008 55 Male 4/30/2008 Physician United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 50 Male 9/12/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Interacting
Wound Drainage Other Serious 9/14/2004 Male 165 lb 9/17/2008 Physician United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Withdrawal Syndrome 8/1/2007 53 Male 9/23/2008 Consumer United States
Primary
Concomitant
Wound Drainage Other Serious 9/14/2004 Male 165 lb 9/25/2008 Physician United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 3/27/2008 79 Female 167 lb 10/10/2008 Pharmacist United States
Primary
Secondary
Concomitant
Impaired Gastric Emptying Hospitalization 10/7/2008 Male 11/12/2008 Pharmacist United States
Primary
Concomitant
Suicidal Ideation Other Serious Female 11/18/2008 Physician Canada
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 11/14/2008 Male 124 lb 11/17/2008 Pharmacist United States
Primary
Concomitant
Product Quality Issue 11/1/2008 Male 195 lb 11/26/2008 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 61 Female 143 lb 1/8/2009 Other Health Professional Brazil
Primary
Concomitant
Death Death 1/1/2007 52 Female 1/15/2009 Other Health Professional United States
Primary
Secondary
Pain In Extremity Hospitalization 5/1/2007 63 Male 1/21/2009 Consumer United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 1/1/2007 52 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Cardio-respiratory Arrest Death 52 Female 3/6/2009 Physician United States
Primary
Secondary
Weight Fluctuation Other Serious 1/1/2004 20 Male 160 lb 4/14/2009 United States
Primary
Concomitant
Drug Ineffective Other Serious 56 Male 4/15/2009
Primary
Secondary
Concomitant
Granuloma Other Serious 5/1/2007 54 Female 4/16/2009
Primary
Secondary
Concomitant
Incisional Hernia Hospitalization Female 487 lb 4/17/2009
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 5/31/2005 33 Female 174 lb 5/21/2009 United States
Primary
Concomitant
Wound Infection Other Serious 3/15/2009 48 Female 5/21/2009 United States
Primary
Concomitant
Skin Necrosis Other Serious 3/15/2009 48 Female 5/21/2009 Other Health Professional United States
Primary
Concomitant
Skin Burning Sensation 4/15/2009 Female 5/27/2009 United States
Primary
Concomitant
Respiratory Rate Increased Hospitalization 5/9/2009 63 Female 110 lb 5/22/2009 Consumer United States
Primary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 3/23/2005 Male 7/7/2009 Consumer Germany
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 4/30/2007 46 Male 161 lb 7/10/2009 Lawyer United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 8/7/2009 United States
Primary
Concomitant
Vertebral Injury Other Serious 1/20/2009 Female 136 lb 8/17/2009 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 8/20/2009 United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 9/2/2009 United States
Primary
Concomitant
Urine Output Decreased Life Threatening 8/31/2009 40 Male 230 lb 9/18/2009 Physician United States
Primary
Concomitant
Withdrawal Syndrome Required Intervention 12/1/2004 Male 1/21/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Death 6/21/2005 54 Female 9/25/2009 Physician United States
Primary
Concomitant
Testicular Pain Other Serious 1/1/2006 Male 230 lb 10/12/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 4/21/2009 46 Male 227 lb 11/3/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 10/5/2009 Female 12/17/2009 United States
Primary
Concomitant
Treatment Noncompliance Required Intervention 8/9/2009 40 Female 135 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/1/2009 Female 223 lb 1/20/2010 Physician United States
Primary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/10/2010 53 Male 176 lb 1/28/2010 Other Health Professional United States
Primary
Concomitant
Hypersensitivity Female 174 lb 2/4/2010 Physician United States
Primary
Concomitant
Spinal Cord Compression Hospitalization 34 Female 2/25/2010
Primary
Secondary
Vibration Test Abnormal Other Serious 65 Male 2/19/2010 Physician United States
Primary
Secondary
Pyrexia Other Serious 66 Female 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Interacting
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2003 57 Female 180 lb 4/20/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/1/2003 57 Female 180 lb 4/27/2010 United States
Primary
Secondary
Concomitant
Hidradenitis Hospitalization 10/5/2009 33 Female 5/7/2010 United States
Primary
Concomitant
Renal Failure Acute Other Serious 54 Male 5/3/2010 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/21/2009 45 Male 5/12/2010 Physician Germany
Primary
Secondary
Concomitant
Hidradenitis Hospitalization 10/5/2009 33 Female 5/27/2010 United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 5/19/2010 73 Male 198 lb 6/1/2010 Pharmacist Ireland
Primary
Concomitant
Uterine Leiomyoma Other Serious 12/1/2003 57 Female 180 lb 6/4/2010 United States
Primary
Secondary
Concomitant

Drug Data