Clonazepam combined with Zopiclone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 2/28/2006 61 Male 5/12/2006 Other Health Professional France
Primary
Concomitant
Interacting
Disease Progression Hospitalization 2/2/2006 57 Male 126 lb 5/24/2006 Physician Chile
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 8/4/2005 56 Female 243 lb 6/14/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 2/1/2005 Female 6/29/2006 Physician United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/8/2004 47 Female 118 lb 8/28/2006 Physician Canada
Primary
Secondary
Concomitant
Vaginal Infection Other Serious 3/1/2006 Female 133 lb 9/11/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Haemorrhage Other Serious 9/8/2006 42 Female 9/21/2006 Pharmacist Canada
Primary
Concomitant
Loss Of Consciousness Other Serious 10/6/2006 Female 12/20/2006 Physician
Primary
Secondary
Concomitant
Sinus Tachycardia Life Threatening 2/20/2006 37 Female 12/21/2006 Other Health Professional France
Primary
Secondary
Sinus Tachycardia Life Threatening 2/20/2006 37 Female 12/29/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vaginal Infection Other Serious 3/1/2006 Female 133 lb 1/23/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Unevaluable Event Other Serious 11/5/2006 Male 156 lb 2/12/2007 Physician France
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 3/23/2006 70 Female 154 lb 2/7/2007 United Kingdom
Primary
Concomitant
Rash Erythematous Hospitalization 1/12/2007 54 Male 2/20/2007 Other Health Professional France
Primary
Secondary
Rash Erythematous Hospitalization 1/12/2007 54 Male 3/6/2007 Other Health Professional France
Primary
Secondary
Weight Increased Hospitalization Male 3/17/2007 Consumer Canada
Primary
Concomitant
Nightmare Other Serious 10/25/2006 Female 108 lb 3/19/2007 Physician France
Primary
Concomitant
Rash Erythematous Hospitalization 1/12/2007 54 Male 4/23/2007 Other Health Professional France
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 1/12/2007 54 Male 4/25/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Disability 1/1/2006 69 Male 4/20/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/28/2007 20 Male 8/24/2007 Physician
Primary
Concomitant
Stress Hospitalization 8/11/2007 29 Female 304 lb 9/10/2007 Consumer United Kingdom
Primary
Concomitant
Pseudophaeochromocytoma Other Serious 31 Female 9/26/2007 Other Health Professional New Zealand
Primary
Concomitant
Raynaud's Phenomenon Other Serious 2/2/2003 43 Female 9/20/2007 Other Health Professional Denmark
Primary
Concomitant
Raynaud's Phenomenon Other Serious 2/2/2003 43 Female 10/2/2007 Denmark
Primary
Concomitant
Shock Hospitalization 7/17/2007 57 Male 9/21/2007 Other Health Professional Poland
Primary
Concomitant
Psychotic Disorder Hospitalization 7/17/2007 57 Male 10/24/2007 Physician Finland
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 80 Female 11/29/2007 Finland
Primary
Concomitant
Transaminases Increased Other Serious 80 Female 11/30/2007
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 5/1/2007 Female 11/30/2007 Physician
Primary
Concomitant
General Physical Health Deterioration Other Serious 3/23/2006 70 Female 154 lb 12/7/2007 United Kingdom
Primary
Concomitant
Dental Caries Other Serious 12/2/2007 Female 1/18/2008 Pharmacist Canada
Primary
Concomitant
Hyperlipidaemia Other Serious 1/12/2008 Female 163 lb 1/30/2008 Pharmacist Canada
Primary
Concomitant
Dysarthria Other Serious Female 183 lb 3/11/2008 Canada
Primary
Concomitant
Transaminases Increased Other Serious 80 Female 3/24/2008 Other Health Professional Finland
Primary
Concomitant
Transaminases Increased Other Serious 80 Female 3/31/2008 Other Health Professional Finland
Primary
Concomitant
Dysarthria Other Serious Female 183 lb 4/4/2008 Canada
Primary
Concomitant
Cryptogenic Organising Pneumonia Hospitalization 3/1/2008 Female 4/15/2008 Physician France
Primary
Concomitant
Withdrawal Syndrome Other Serious 11/22/2002 32 Female 4/16/2008 Physician United Kingdom
Primary
Concomitant
Hyperlipidaemia Other Serious 1/12/2008 Female 163 lb 4/25/2008 Pharmacist Canada
Primary
Concomitant
Psychotic Disorder Hospitalization 7/17/2007 57 Male 4/30/2008 Physician Finland
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 7/17/2007 57 Male 4/25/2008 Physician Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 11/22/2002 32 Female 5/21/2008 Physician United Kingdom
Primary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Substance Abuse Other Serious 50 Male 6/11/2008 Physician Canada
Primary
Secondary
Withdrawal Syndrome Other Serious 11/22/2002 32 Female 6/23/2008 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Death 4/11/2008 Male 6/17/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 31 Male 6/26/2008 Consumer Canada
Primary
Concomitant
Pain In Extremity Other Serious 6/20/2008 64 Male 8/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/30/2008 Female 155 lb 9/3/2008 Consumer Canada
Primary
Concomitant
Depression Disability 6/27/2007 54 Male 9/11/2008 Physician Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2008 Male 10/24/2008 Consumer Canada
Primary
Secondary
Concomitant
Interacting
Joint Effusion Other Serious Female 175 lb 11/10/2008 Canada
Primary
Concomitant
Ear Operation Other Serious 12/1/2008 Female 238 lb 12/23/2008 Other Health Professional Canada
Primary
Concomitant
Drug Interaction Other Serious 54 Male 12/31/2008 Other Health Professional Canada
Primary
Secondary
Interacting
Drug Interaction Other Serious 6/20/2007 54 Male 1/12/2009 Physician Canada
Primary
Secondary
Concomitant
Interacting
Schizophrenia Hospitalization 11/23/2008 43 Male 198 lb 1/14/2009 Other Health Professional Australia
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 2/6/2009 75 Female 3/3/2009 Consumer Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/25/2009 Male 4/9/2009 Physician New Zealand
Primary
Secondary
Concomitant
Fracture Delayed Union Other Serious 2/6/2009 75 Female 4/3/2009 Physician Canada
Primary
Concomitant
Fracture Delayed Union Other Serious 2/6/2009 75 Female 5/5/2009 Physician Canada
Primary
Concomitant
Sedation Other Serious 1/1/2004 Male 5/26/2009 Other Health Professional Canada
Primary
Concomitant
Sedation Other Serious 1/1/2004 Male 6/4/2009 Other Health Professional Canada
Primary
Concomitant
Myoclonus Hospitalization 8/19/2008 Female 6/30/2009 Physician France
Primary
Secondary
Concomitant
Myoclonus Hospitalization 8/19/2008 Female 6/30/2009 Physician France
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/14/2009 49 Male 7/21/2009 Other Health Professional France
Primary
Secondary
Concomitant
Ear Operation Other Serious 12/1/2008 Female 238 lb 7/23/2009 Other Health Professional Canada
Primary
Concomitant
Viral Myocarditis Other Serious 41 Male 9/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Viral Myocarditis Death 41 Male 9/18/2009 Consumer United Kingdom
Primary
Secondary
Renal Impairment Death 41 Male 9/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 23 Female 10/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 23 Female 10/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 52 Male 10/21/2009 Physician Canada
Primary
Secondary
Thrombocytopenia Other Serious 6/8/2009 56 Male 10/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/14/2009 49 Male 10/29/2009 Other Health Professional France
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/1/2009 Female 130 lb 11/4/2009 Canada
Primary
Concomitant
Tendon Disorder Other Serious Female 11/18/2009 Canada
Primary
Concomitant
Fracture Delayed Union Other Serious 2/6/2009 75 Female 12/1/2009 Physician Canada
Primary
Concomitant
Pruritus Other Serious 10/1/2009 60 Male 265 lb 12/12/2009 Other Health Professional
Primary
Concomitant
Pruritus Other Serious 10/1/2009 60 Male 265 lb 2/25/2010 Other Health Professional
Primary
Concomitant
Thrombocytopenia Other Serious 6/8/2009 56 Male 3/1/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pain Disability 3/7/2010 69 Female 3/23/2010 Consumer Canada
Primary
Concomitant
Malignant Neoplasm Progression Death Female 3/25/2010 Physician Canada
Primary
Concomitant
Intestinal Perforation Other Serious 1/6/2010 73 Male 4/16/2010 Consumer United Kingdom
Primary
Concomitant
Intestinal Perforation Hospitalization 1/5/2010 73 Male 4/20/2010 Pharmacist United Kingdom
Primary
Concomitant
Gait Disturbance Other Serious 1/1/2008 59 Female 110 lb 5/5/2010 Other Health Professional Sweden
Primary
Concomitant
Interacting
Off Label Use Hospitalization 2/11/2009 45 Male 148 lb 5/26/2010 Physician Canada
Primary
Concomitant
Sleep Disorder Other Serious Male 6/21/2010 Consumer Canada
Primary
Concomitant
Drug Interaction Other Serious 54 Male 7/13/2010 Other Health Professional Canada
Primary
Secondary
Drug Interaction Other Serious 54 Male 7/15/2010 Consumer United States
Primary
Interacting
Tardive Dyskinesia Hospitalization 73 Male 7/19/2010 Physician Japan
Primary
Secondary
Concomitant
Tardive Dyskinesia Hospitalization 5/1/2009 73 Male 7/20/2010 Physician Japan
Primary
Secondary
Concomitant
Tardive Dyskinesia Hospitalization 73 Male 7/29/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization Female 180 lb 8/18/2010 Physician Canada
Primary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 9/10/2010 Physician Sweden
Primary
Concomitant
Interacting
Drug Interaction Other Serious 54 Male 9/10/2010 Other Health Professional Canada
Primary
Secondary
Vertigo Other Serious 1/1/2000 59 Female 110 lb 9/15/2010 Other Health Professional Sweden
Primary
Concomitant
Interacting
Lung Infiltration Other Serious 1/1/2000 59 Female 110 lb 9/23/2010
Primary
Secondary
Vertigo Other Serious 59 Female 110 lb 9/29/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious Female 10/1/2010 Other Health Professional New Zealand
Primary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 10/13/2010 Physician Sweden
Primary
Concomitant
Interacting
Vertigo Other Serious 59 Female 110 lb 10/15/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 3/1/2010 11/12/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 3/1/2010 11/23/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Overdose Other Serious 7/22/2010 37 Male 11/30/2010 Other Health Professional Ireland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/12/2010 75 Female 12/28/2010 Other Health Professional France
Primary
Secondary
Concomitant
Yellow Skin 11/1/2010 61 Female 12/29/2010 Consumer Canada
Primary
Concomitant
Upper Limb Fracture Hospitalization 12/31/2010 61 Female 145 lb 1/13/2011 Other Health Professional Canada
Primary
Concomitant
Depression Other Serious Male 2/8/2011 Consumer Canada
Primary
Concomitant
Upper Limb Fracture Hospitalization 12/31/2010 61 Female 145 lb 3/2/2011 Other Health Professional Canada
Primary
Concomitant
Polyp Colorectal Hospitalization 12/30/2010 62 Female 3/8/2011 Consumer Canada
Primary
Concomitant
Vision Blurred 9/1/2010 61 Female 183 lb 3/14/2011 Physician Canada
Primary
Concomitant
Physical Assault Other Serious 12/1/2010 26 Male 3/17/2011 Physician New Zealand
Primary
Concomitant
Pathological Fracture Hospitalization 12/30/2010 62 Female 4/12/2011 Physician Canada
Primary
Concomitant
Atrial Fibrillation Other Serious 12/1/2010 71 Female 127 lb 4/27/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Blood Triglycerides Increased Hospitalization 1/29/2007 34 Male 240 lb 5/10/2011 Consumer Canada
Primary
Concomitant
Musculoskeletal Discomfort Other Serious 5/18/2011 56 Female 345 lb 6/1/2011 Other Health Professional Canada
Primary
Concomitant
Irritable Bowel Syndrome Other Serious Male 215 lb 6/2/2011 Physician Canada
Primary
Secondary
Concomitant
Neoplasm Malignant Death Male 6/8/2011 Physician United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 59 Female 6/21/2011 Other Health Professional Sweden
Primary
Concomitant
Eye Haemorrhage Other Serious 5/19/2011 39 Male 187 lb 6/30/2011 Physician France
Primary
Concomitant
Abdominal Pain Lower Other Serious 6/2/2011 56 Female 358 lb 7/8/2011 Other Health Professional Canada
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization Male 7/6/2011 Physician Canada
Primary
Concomitant
Transient Ischaemic Attack 5/19/2011 39 Male 187 lb 7/21/2011 Physician France
Primary
Concomitant
Psychotic Disorder Hospitalization 2/1/2011 85 Female 7/22/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Subcutaneous Other Serious 7/20/2000 41 Male 7/21/2011 Physician Canada
Primary
Concomitant
Hepatic Encephalopathy Other Serious 10/19/2004 54 Male 8/8/2011 Physician Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 6/2/2011 56 Female 358 lb 8/12/2011 Other Health Professional Canada
Primary
Concomitant
Renal Failure Other Serious 5/14/2010 58 Male 8/9/2011 Consumer Canada
Primary
Secondary
Concomitant
Self Esteem Decreased Life Threatening 7/22/2010 37 Male 8/23/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Self Esteem Decreased Hospitalization 7/22/2010 37 Male 8/23/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 12/30/2010 62 Female 134 lb 8/18/2011 Consumer Canada
Primary
Concomitant
Tuberculosis Other Serious 12/21/2005 74 Female 8/23/2011 Physician Canada
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 7/1/2011 49 Female 8/29/2011 Other Health Professional Ireland
Primary
Concomitant
Mania Hospitalization 29 Female 142 lb 8/30/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Other Serious Male 231 lb 8/29/2011 Physician Canada
Primary
Concomitant
Mania Hospitalization 29 Female 142 lb 8/31/2011 Other Health Professional United Kingdom
Primary
Concomitant
Blood Cholesterol Increased Other Serious 8/15/2005 44 Female 9/1/2011 Consumer Canada
Primary
Concomitant
Weight Increased 3/2/2001 49 Male 9/2/2011 Physician Canada
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 12/9/2006 64 Male 9/12/2011 Consumer Canada
Primary
Secondary
Concomitant
No Adverse Event Other Serious Female 9/17/2011 Consumer Canada
Primary
Concomitant
Atrioventricular Block Hospitalization 8/25/2011 71 Female 9/22/2011 Other Health Professional New Zealand
Primary
Concomitant
Overdose Hospitalization Male 9/22/2011 Consumer Canada
Primary
Concomitant
Fall Hospitalization 8/8/2011 91 Male 10/6/2011 Other Health Professional France
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2007 48 Male 9/29/2011 Consumer Canada
Primary
Concomitant
Suicide Attempt Life Threatening 5/25/2011 58 Female 10/10/2011 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Acidosis Hospitalization 5/25/2011 58 Female 10/17/2011 Other Health Professional France
Primary
Secondary
Concomitant
Neutrophilia Other Serious 7/1/2011 49 Female 10/27/2011 Physician Ireland
Primary
Concomitant

Drug Data