Clonazepam combined with Xyrem

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Ketone Body Present Life Threatening 5/3/2006 54 Female 160 lb 5/23/2006 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance 4/23/2006 55 Female 4/23/2006 Pharmacist United States
Primary
Concomitant
Periorbital Haematoma Other Serious 11/4/2006 49 Female 170 lb 11/17/2006 Other Health Professional United States
Primary
Concomitant
Condition Aggravated Death 4/1/2007 61 Female 4/6/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 51 Male 167 lb 9/13/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 10/1/2007 63 Female 11/6/2007 Physician United States
Primary
Secondary
Concomitant
Somnambulism Other Serious Female 146 lb 3/6/2008 Consumer United States
Primary
Concomitant
Somnolence Other Serious 1/25/2008 49 Female 205 lb 4/23/2008 United States
Primary
Secondary
Concomitant
Pelvic Fracture Other Serious 3/1/2008 31 Female 5/7/2008 Consumer United States
Primary
Concomitant
Death Death 7/19/2008 53 Female 8/28/2008 Physician United States
Primary
Concomitant
Pollakiuria Other Serious 6/27/2008 34 Male 154 lb 8/29/2008 Consumer United States
Primary
Concomitant
Restlessness Other Serious 6/27/2008 34 Male 154 lb 9/11/2008 Consumer United States
Primary
Concomitant
Road Traffic Accident Death 4/14/2008 63 Female 9/12/2008 Physician Norway
Primary
Concomitant
Weight Decreased Other Serious 6/27/2008 34 Male 154 lb 9/25/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 6/27/2008 34 Male 154 lb 10/9/2008 Physician United States
Primary
Concomitant
Memory Impairment Required Intervention 3/1/2008 52 Female 158 lb 10/16/2008 Consumer United States
Primary
Concomitant
Memory Impairment Other Serious 3/1/2008 52 Female 185 lb 11/5/2008 Other Health Professional United States
Primary
Concomitant
Impulse-control Disorder 1/1/2008 40 Female 200 lb 10/15/2008 Consumer United States
Primary
Concomitant
Lower Limb Fracture Hospitalization 7/28/2008 56 Female 180 lb 11/14/2008 Consumer United States
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Other Serious 47 Female 107 lb 11/26/2008 Consumer United States
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 11/1/2008 61 Female 210 lb 12/17/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 6/27/2008 34 Male 154 lb 2/4/2009 Physician United States
Primary
Concomitant
Hernia Other Serious 1/1/2009 53 Female 188 lb 2/13/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/1/2008 20 Male 2/23/2009 Belgium
Primary
Secondary
Weight Decreased Other Serious 6/27/2008 34 Male 154 lb 3/26/2009 Physician United States
Primary
Concomitant
X-linked Chromosomal Disorder Other Serious 12/1/2008 20 Male 4/23/2009 Belgium
Primary
Secondary
Sleep Apnoea Syndrome Other Serious 12/1/2008 20 Male 4/30/2009 Belgium
Primary
Secondary
Tooth Abscess Other Serious 1/23/2008 54 Female 165 lb 7/17/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2009 43 Female 152 lb 8/11/2009 Other Health Professional United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2009 52 Male 174 lb 8/31/2009 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 47 Female 142 lb 10/6/2009 Consumer United States
Primary
Concomitant
Spinal Fracture Other Serious 12/8/2007 47 Female 130 lb 12/4/2009 Physician United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2006 36 Female 263 lb 11/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Hospitalization 3/23/2010 25 Male 165 lb 3/30/2010 Consumer United States
Primary
Concomitant
Urine Odour Abnormal Hospitalization 1/1/2010 58 Female 143 lb 4/5/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 9/1/2009 50 Male 267 lb 4/13/2010 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Hospitalization 3/2/2010 37 Female 179 lb 4/9/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2010 25 Male 165 lb 4/30/2010 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2008 42 Female 4/23/2010 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2008 42 Female 4/30/2010 Physician United States
Primary
Concomitant
Muscular Weakness Hospitalization 7/1/2009 67 Female 5/19/2010 Consumer United States
Primary
Secondary
Concomitant
Cellulitis Other Serious 44 Female 6/4/2010 Consumer United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 5/27/2010 54 Female 130 lb 6/16/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 11/1/2008 Female 180 lb 9/9/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 1/1/2010 48 Female 9/28/2010 Consumer United States
Primary
Concomitant
Pain Other Serious 11/1/2008 59 Female 155 lb 9/30/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2010 38 Male 10/26/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 48 Female 200 lb 10/21/2010 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2008 41 Female 145 lb 12/6/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 48 Female 200 lb 12/10/2010 Consumer United States
Primary
Secondary
Concomitant
Insomnia Hospitalization 1/1/2010 51 Female 130 lb 12/13/2010 Consumer United States
Primary
Concomitant
Mental Disorder Other Serious 12/6/2010 30 Female 116 lb 12/21/2010 United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 1/1/2010 25 Male 157 lb 1/12/2011 Consumer United States
Primary
Secondary
Concomitant
Exophthalmos Other Serious 2/6/2011 51 Male 195 lb 2/17/2011 Other Health Professional United States
Primary
Concomitant
Depression Other Serious 1/1/2007 60 Female 180 lb 2/16/2011 Consumer United States
Primary
Secondary
Concomitant
Trismus Other Serious 2/1/2011 51 Male 195 lb 3/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Clostridial Infection Hospitalization 1/30/2011 43 Female 3/7/2011 Consumer United States
Primary
Concomitant
Feeling Abnormal Hospitalization 2/1/2011 40 Female 205 lb 3/4/2011 Consumer United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 9/13/2010 43 Female 3/16/2011 Physician United States
Primary
Concomitant
Clostridial Infection Hospitalization 9/13/2010 43 Female 3/16/2011 Physician United States
Primary
Concomitant
Vitamin D Deficiency Hospitalization 1/1/2009 39 Female 238 lb 3/21/2011 Consumer United States
Primary
Concomitant
Feeling Abnormal Other Serious 1/1/2009 48 Female 200 lb 3/21/2011 Consumer United States
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 6/1/2009 28 Female 125 lb 3/22/2011 Consumer United States
Primary
Secondary
Concomitant
Anxiety Other Serious 1/1/2011 38 Female 148 lb 4/1/2011 Consumer United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 3/27/2011 57 Female 4/5/2011 Consumer United States
Primary
Secondary
Rash Maculo-papular Other Serious 8/1/2007 64 Female 160 lb 4/7/2011 Consumer United States
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 8/1/2007 64 Female 160 lb 4/7/2011 Consumer United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Other Serious 1/1/2009 39 Female 232 lb 4/26/2011 Consumer United States
Primary
Concomitant
Ear Infection Fungal Hospitalization 9/13/2010 43 Female 190 lb 4/28/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 4/18/2011 30 Female 125 lb 5/27/2011 Consumer United States
Primary
Concomitant
Road Traffic Accident Death 11/27/2006 53 Male 5/24/2011 Physician United States
Primary
Concomitant
Multiple Drug Overdose Other Serious 6/15/2011 47 Female 189 lb 6/28/2011 Consumer United States
Primary
Secondary
Concomitant
Initial Insomnia Other Serious 1/1/2009 39 Female 232 lb 7/13/2011 Consumer United States
Primary
Concomitant
Skeletal Injury Other Serious 6/1/2009 34 Male 190 lb 8/2/2011 Consumer United States
Primary
Concomitant
Burns Third Degree Other Serious 4/1/2011 39 Female 145 lb 8/5/2011 Consumer United States
Primary
Concomitant
Fatigue Other Serious 6/1/2010 51 Female 279 lb 8/4/2011 United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Death 4/1/2007 61 Female 8/15/2011 Consumer United States
Primary
Concomitant
Tooth Abscess Other Serious 1/23/2008 54 Female 149 lb 8/17/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2010 52 Female 160 lb 8/29/2011 Consumer United States
Primary
Concomitant
Abscess Hospitalization 9/13/2010 43 Female 205 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2007 55 Male 198 lb 9/20/2011 Physician United States
Primary
Concomitant
Endometriosis Other Serious 1/1/2009 29 Female 120 lb 9/23/2011 Consumer United States
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 1/1/2010 65 Male 245 lb 10/11/2011 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2009 62 Male 211 lb 10/5/2011 Consumer United States
Primary
Concomitant
Surgical Failure Other Serious 1/23/2008 54 Female 165 lb 10/18/2011 Consumer United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 1/1/2010 65 Male 243 lb 10/27/2011 Consumer United States
Primary
Concomitant
Road Traffic Accident Hospitalization 11/15/2010 37 Female 211 lb 11/23/2011 Consumer United States
Primary
Concomitant
Dehydration Other Serious 6/15/2011 47 Female 189 lb 11/23/2011 Consumer United States
Primary
Secondary
Concomitant
Surgical Failure Other Serious 1/23/2008 54 Female 187 lb 11/22/2011 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 6/1/2009 28 Female 125 lb 11/21/2011 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 6/1/2009 28 Female 125 lb 12/5/2011 Physician United States
Primary
Secondary
Concomitant
Dysstasia Hospitalization 6/15/2011 47 Female 189 lb 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 11/3/2011 54 Male 12/12/2011 Physician United States
Primary
Concomitant
Dizziness Death 7/26/2008 53 Female 12/22/2011 Physician United States
Primary
Concomitant
Initial Insomnia Hospitalization 1/1/2010 58 Female 143 lb 1/13/2012 Consumer United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Death 7/12/2008 53 Female 1/13/2012 Physician United States
Primary
Concomitant
Back Pain Hospitalization 11/1/2011 61 Male 205 lb 1/26/2012 Consumer United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 1/1/2011 48 Female 1/26/2012 Physician United States
Primary
Concomitant
Nausea Hospitalization 8/1/2011 22 Male 2/8/2012 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2007 45 Male 2/8/2012 Physician France
Primary
Secondary
Concomitant
Convulsion Hospitalization 8/1/2011 22 Male 2/17/2012 Physician United States
Primary
Secondary
Concomitant
Terminal Insomnia Hospitalization 2/2/2012 39 Female 2/21/2012 Physician United States
Primary
Concomitant
Post Concussion Syndrome Other Serious 1/1/2009 51 Male 250 lb 2/29/2012 Consumer United States
Primary
Concomitant
Sedation Other Serious 1/1/2011 48 Male 198 lb 3/1/2012 Consumer United States
Primary
Concomitant
Panic Attack Other Serious 1/1/2009 47 Female 3/1/2012 Physician United States
Primary
Concomitant
Sedation Hospitalization 1/1/2011 48 Male 198 lb 3/5/2012 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 2/28/2012 41 Female 157 lb 3/9/2012 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 1/1/2009 51 Male 250 lb 3/14/2012 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2011 45 Female 207 lb 3/30/2012 Physician United States
Primary
Concomitant
Breast Cancer Female Other Serious 3/19/2012 55 Female 4/4/2012 Consumer United States
Primary
Concomitant
Breast Cancer Other Serious 3/19/2012 55 Female 4/11/2012 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2010 51 Female 160 lb 4/10/2012 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 3/19/2012 55 Female 4/16/2012 Other Health Professional United States
Primary
Concomitant
Acne 7/26/2010 17 Male 150 lb 5/2/2012 Consumer United States
Primary
Concomitant
Nausea Other Serious 1/1/2012 60 Female 122 lb 4/27/2012 Physician United States
Primary
Concomitant
Insomnia Hospitalization 11/23/2011 39 Female 4/27/2012 Physician United States
Primary
Secondary
Concomitant
Lymphadenectomy Other Serious 3/26/2012 53 Male 225 lb 5/3/2012 Consumer United States
Primary
Secondary
Concomitant
Palpitations Hospitalization 4/20/2012 32 Female 5/9/2012 Physician United States
Primary
Concomitant
Bronchitis Death 4/16/2012 43 Female 5/8/2012 Consumer United States
Primary
Concomitant
Heart Rate Increased Other Serious 3/26/2012 53 Male 225 lb 5/11/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Pressure Systolic Increased Disability 10/1/2011 60 Female 125 lb 5/31/2012 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Disability 10/1/2011 60 Female 125 lb 6/5/2012 Physician United States
Primary
Secondary
Concomitant
Multiple Allergies Other Serious 1/1/2010 33 Female 315 lb 6/5/2012 Consumer United States
Primary
Secondary
Concomitant
Victim Of Crime Hospitalization 5/1/2012 40 Male 175 lb 6/12/2012 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious 1/1/2010 63 Female 116 lb 6/15/2012 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 31 Male 6/25/2012 Consumer United States
Primary
Secondary
Concomitant
Activities Of Daily Living Impaired Other Serious 10/1/2011 60 Female 125 lb 7/3/2012 Physician United States
Primary
Secondary
Concomitant
Restlessness Other Serious 1/1/2008 59 Female 7/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Seborrhoea Other Serious 1/1/2008 59 Female 7/9/2012 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Thrombosis Hospitalization 1/1/2012 56 Male 7/16/2012 Physician United States
Primary
Concomitant
Asthenia Other Serious 1/1/2010 63 Female 116 lb 7/17/2012 Consumer United States
Primary
Concomitant
Crying Other Serious 1/1/2008 59 Female 7/16/2012 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/1/2012 41 Female 7/19/2012 Consumer United States
Primary
Secondary
Concomitant
Anxiety Hospitalization 3/1/2012 22 Female 7/23/2012 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 2009 29 Female 120 lb 10/12/2012 Consumer Us
Primary
Concomitant
Somnambulism Death 11/3/2011 54 Male 9/14/2012 Physician Us
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/2011 22 Male 1/16/2013 Physician Us
Primary
Secondary
Concomitant
Weight Increased Disability 10/2011 60 Female 134 lb 10/9/2012 Physician Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 2010 33 Female 315 lb 10/17/2012 Registered Nurse Us
Primary
Secondary
Concomitant
Weight Increased Hospitalization 11/2011 56 Male 260 lb 1/16/2013 Physician Us
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 2012 41 Female 8/9/2012 Physician Us
Primary
Secondary
Concomitant
Tongue Disorder Other Serious 8/3/2012 50 Female 230 lb 9/4/2012 Physician Us
Primary
Concomitant
Suicidal Ideation Other Serious 7/2012 49 Female 9/28/2012 Physician Us
Primary
Secondary
Plasma Cell Myeloma Other Serious 5/2012 54 Male 9/5/2012 Physician Us
Primary
Concomitant
Plasma Cell Myeloma Other Serious 5/2012 54 Male 12/21/2012 Physician Us
Primary
Concomitant
Wrist Fracture Other Serious 1/27/2012 30 Female 8/22/2012 Us
Primary
Secondary
Stress Hospitalization 5/2012 58 Male 195 lb 2/27/2013 Consumer Us
Primary
Concomitant
Vomiting Other Serious 10/2012 22 Female 105 lb 12/18/2012 Consumer Us
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2012 51 Male 225 lb 12/24/2012 Physician Us
Primary
Concomitant
Somnambulism Hospitalization 3/23/2012 59 Female 100 lb 3/7/2013 Physician Us
Primary
Concomitant

Drug Data