Clonazepam combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Overdose Other Serious 8/4/2001 48 Female 1/27/2006 Consumer Canada
Primary
Concomitant
Swelling Hospitalization 10/28/2005 34 Male 1/25/2006 Pharmacist United States
Primary
Secondary
Hemivertebra Congenital Anomaly 2/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Initial Insomnia 1/1/2005 47 Female 130 lb 1/5/2006 Consumer United States
Primary
Concomitant
Dysgeusia 9/1/2005 28 Female 1/5/2006 Pharmacist United States
Primary
Concomitant
Vomiting 49 Female 2/27/2006 Consumer United States
Primary
Concomitant
Rash 3/1/2005 Female 2/28/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/2/2001 44 Female 201 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 44 Female 201 lb 3/23/2006 Physician United States
Primary
Concomitant
Visual Field Defect Other Serious 3/9/2005 46 Male 245 lb 3/17/2006 United States
Primary
Concomitant
Visual Field Defect Other Serious 3/9/2005 46 Male 245 lb 3/21/2006 United States
Primary
Concomitant
Speech Disorder Disability 5/1/2002 Female 3/27/2006 Canada
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 3/9/2005 46 Male 245 lb 4/3/2006 Consumer United States
Primary
Concomitant
Infusion Related Reaction Hospitalization 1/1/2006 Female 300 lb 4/18/2006 Consumer United States
Primary
Concomitant
Purpura Other Serious 46 Female 211 lb 4/14/2006 Other Health Professional United States
Primary
Concomitant
Purpura Other Serious 46 Female 211 lb 4/14/2006 Other Health Professional United States
Primary
Concomitant
Volvulus Hospitalization 11/22/2005 53 Female 155 lb 5/2/2006 Consumer United States
Primary
Concomitant
Lethargy Other Serious 26 Female 5/25/2006 Consumer Canada
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious Female 190 lb 6/1/2006 Physician Canada
Primary
Concomitant
Pyrexia Hospitalization 1/1/2006 18 Female 121 lb 6/7/2006 Physician Brazil
Primary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2006 Female 300 lb 6/12/2006 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 8/4/2005 56 Female 243 lb 6/14/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2006 18 Female 121 lb 6/22/2006 Physician Brazil
Primary
Concomitant
Tinnitus Other Serious 37 Male 7/6/2006 Pharmacist United States
Primary
Concomitant
Tinnitus Other Serious 5/1/2004 45 Male 7/14/2006 Pharmacist United States
Primary
Concomitant
Epilepsy Other Serious 3/23/2006 44 Female 97 lb 6/12/2006 Consumer United States
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Brain Abnormal Other Serious 1/1/2005 43 Female 135 lb 7/31/2006 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 5/1/2006 50 Female 8/3/2006 Canada
Primary
Concomitant
Road Traffic Accident Other Serious Female 190 lb 8/10/2006 Physician Canada
Primary
Concomitant
Weight Increased Other Serious 6/22/2004 Male 8/17/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 57 Female 244 lb 7/19/2006 United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 5/1/2006 50 Female 8/29/2006 Other Health Professional Canada
Primary
Concomitant
Drug Level Increased Hospitalization 43 Male 9/15/2006 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 5/1/2006 50 Female 9/22/2006 Other Health Professional Canada
Primary
Concomitant
Hyponatraemia Hospitalization 8/27/2006 7 Female 9/25/2006 Canada
Primary
Concomitant
Tachypnoea Hospitalization 42 Male 420 lb 10/30/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1997 38 Female 176 lb 8/18/2006 United States
Primary
Concomitant
Stag Horn Calculus Other Serious 3/29/2005 2 Female 22 lb 8/18/2006 Physician United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 5/5/2005 74 Female 11/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 9/19/2006 57 Male 195 lb 12/5/2006 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 9/28/2006 35 Female 12/14/2006 Other Health Professional United States
Primary
Concomitant
Cataract Hospitalization 5/27/2003 19 Female 12/29/2006 Physician Thailand
Primary
Concomitant
Cataract Hospitalization 5/27/2003 19 Female 1/9/2007 Physician Thailand
Primary
Concomitant
Dyskinesia 57 Female 12/29/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 149 lb 1/11/2007 Physician Canada
Primary
Secondary
Concomitant
Hemiparesis Other Serious 1/1/2004 Female 180 lb 1/18/2007 Consumer United States
Primary
Concomitant
Epilepsy Other Serious 3/23/2006 43 Female 96 lb 11/14/2006 United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 50 Male 172 lb 1/26/2007 Physician United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 1/1/2007 52 Female 223 lb 1/26/2007 Other Health Professional United States
Primary
Concomitant
Hemiparesis Other Serious 1/1/2004 Female 180 lb 2/2/2007 Consumer United States
Primary
Concomitant
Nausea Death 50 Male 172 lb 1/26/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2003 47 Female 290 lb 2/22/2007 Consumer United States
Primary
Concomitant
Renal Disorder Other Serious 10 Male 44 lb 3/16/2007 Physician Mexico
Primary
Concomitant
Renal Disorder Other Serious 10 Male 44 lb 3/27/2007 Physician Mexico
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2005 23 Female 12/4/2006 United States
Primary
Secondary
Concomitant
Renal Cyst Disability 3/20/2006 60 Female 12/4/2006 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 2/18/2007 48 Female 321 lb 4/2/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 30 Male 4/13/2007 Consumer United Kingdom
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/1/2007 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 3/22/2007 37 Female 4/23/2007 Consumer United States
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 2/5/2007 39 Female 178 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 3/28/2007 United States
Primary
Secondary
Concomitant
Initial Insomnia 1/1/2006 50 Female 180 lb 4/12/2007 Consumer United States
Primary
Concomitant
Venous Occlusion Hospitalization 5/23/2007 44 Female 150 lb 6/8/2007 Consumer Brazil
Primary
Concomitant
Weight Increased Other Serious 6/3/2003 40 Female 130 lb 4/2/2007 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 2/18/2007 48 Female 321 lb 6/22/2007 Physician United States
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 6/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 2/1/2007 Female 6/29/2007 Pharmacist Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 136 lb 7/5/2007 Consumer United States
Primary
Concomitant
Status Epilepticus Other Serious Female 7/26/2007 Consumer United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 7/23/2007 18 Female 8/3/2007 Physician Colombia
Primary
Concomitant
Dysgeusia 5/1/2007 46 Female 115 lb 7/10/2007 Consumer United States
Primary
Concomitant
Urticaria Other Serious 1/1/2007 Female 189 lb 8/16/2007 Consumer United States
Primary
Secondary
Concomitant
Status Epilepticus Other Serious Female 8/22/2007 United States
Primary
Secondary
Concomitant
Hemiparesis Other Serious 1/1/2004 Female 180 lb 9/18/2007 Consumer United States
Primary
Concomitant
Pathological Gambling 11/9/2005 Female 10/1/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint 9/7/2006 30 Female 10/25/2007 Consumer United States
Primary
Concomitant
Somnolence Other Serious 7/1/2006 58 Female 145 lb 10/11/2007 United States
Primary
Concomitant
Pathological Gambling 11/9/2005 Female 11/5/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 6/22/2004 45 Male 11/19/2007 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2005 Female 166 lb 11/20/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 49 Female 11/30/2007 Consumer United States
Primary
Concomitant
Weight Increased Life Threatening 6/8/2007 24 Female 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Migraine 5/1/2007 48 Female 50 lb 12/17/2007 United States
Primary
Concomitant
Renal Cyst Disability 3/20/2006 60 Female 11/19/2007 Physician United States
Primary
Secondary
Concomitant
Insomnia Death 54 Female 100 lb 1/14/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 261 lb 1/18/2008 Physician United States
Primary
Concomitant
Epilepsy Other Serious 3/23/2006 44 Female 97 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2000 Female 150 lb 1/28/2008 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2005 Female 166 lb 2/4/2008 Physician United States
Primary
Secondary
Concomitant
Drug Effect Decreased Hospitalization 8/17/2007 41 NotSpecified 172 lb 2/4/2008 Physician China
Primary
Secondary
Concomitant
Depression Hospitalization 8/17/2007 41 Male 172 lb 1/31/2008 Physician China
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/1/2001 Female 150 lb 2/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/1/2001 Female 150 lb 3/4/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2007 51 Female 419 lb 1/10/2008 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2005 Female 166 lb 3/6/2008 Physician United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Other Serious 1/1/2007 41 Female 3/11/2008 Consumer United States
Primary
Concomitant
Drug Effect Decreased 50 Male 3/7/2008 Pharmacist United States
Primary
Concomitant
Suicide Attempt Other Serious 2/1/2003 Female 3/14/2008 Consumer United States
Primary
Concomitant
Sciatica Hospitalization 1/28/2008 47 Female 265 lb 3/10/2008 United States
Primary
Concomitant
Pruritus Other Serious 1/18/2008 32 Female 3/18/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 8/1/2001 Female 150 lb 4/1/2008 Pharmacist United States
Primary
Secondary
Concomitant
Pruritus Other Serious 1/18/2008 32 Female 4/2/2008 Physician United States
Primary
Concomitant
Suicidal Ideation Hospitalization 8/1/2006 Female 4/1/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/29/2008 Male 4/15/2008 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Hospitalization Female 205 lb 4/22/2008 Pharmacist Australia
Primary
Concomitant
Treatment Noncompliance Hospitalization 3/1/2008 Female 4/21/2008 Consumer United States
Primary
Concomitant
Thinking Abnormal Hospitalization 3/1/2008 Female 4/30/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious Female 180 lb 5/2/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization Female 205 lb 5/2/2008 Pharmacist Australia
Primary
Concomitant
Pruritus Other Serious 1/18/2008 32 Female 5/9/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2008 Female 200 lb 5/20/2008 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 2/1/2003 Female 6/10/2008 Consumer United States
Primary
Concomitant
Convulsion Neonatal Death 6/11/2008 Other Health Professional Israel
Primary
Secondary
Weight Increased 3/1/2003 Female 240 lb 6/12/2008 Consumer United States
Primary
Concomitant
Violence-related Symptom Other Serious 5/29/2008 41 Female 6/13/2008 Consumer United States
Primary
Concomitant
Nerve Degeneration Other Serious 5/1/2008 43 Female 154 lb 6/11/2008 Physician United States
Primary
Concomitant
Weight Decreased 1/1/2007 51 Female 419 lb 4/10/2008 Consumer United States
Primary
Concomitant
Syncope Other Serious 7/1/2006 Female 130 lb 6/17/2008 United States
Primary
Concomitant
Thinking Abnormal Hospitalization 3/1/2008 Female 6/17/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2004 46 Male 249 lb 6/18/2008 Consumer Mexico
Primary
Concomitant
Thrombosis Hospitalization 10/1/2007 Male 210 lb 6/27/2008 Consumer United States
Primary
Concomitant
Urticaria 1/1/1994 30 Female 7/15/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 7/27/2007 65 Male 201 lb 7/29/2008 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 2/1/2008 28 Female 200 lb 7/31/2008 Consumer United States
Primary
Concomitant
Restless Legs Syndrome Hospitalization 1/1/2005 Female 120 lb 8/7/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 1/1/1999 Female 8/8/2008 Consumer United States
Primary
Concomitant
Hip Dysplasia Other Serious Female 7 lb 8/11/2008 United Kingdom
Primary
Secondary
Throat Tightness Other Serious 4/29/2008 Female 160 lb 8/20/2008 Physician United States
Primary
Concomitant
Deafness Unilateral Other Serious 6/28/2008 38 Female 8/25/2008 Physician Canada
Primary
Concomitant
Viral Infection Other Serious 3/1/2008 Female 290 lb 9/3/2008 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/26/2008 Female 158 lb 9/11/2008 Physician United States
Primary
Concomitant
Throat Tightness Other Serious 4/1/2008 Female 160 lb 9/17/2008 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 5/21/2008 35 Female 9/15/2008 Consumer United States
Primary
Concomitant
Pruritus Other Serious 5/1/2006 38 Female 200 lb 7/11/2008 Consumer United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2008 Female 130 lb 10/3/2008 Physician United States
Primary
Concomitant
Malignant Melanoma Stage I Other Serious 5/1/2008 43 Female 154 lb 9/30/2008 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 5/21/2008 35 Female 9/30/2008 United States
Primary
Concomitant
Pneumonia Aspiration Life Threatening 6/6/2008 53 Female 10/3/2008 United States
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 3/1/2008 53 Female 112 lb 10/13/2008 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2008 Male 10/24/2008 Consumer Canada
Primary
Secondary
Concomitant
Interacting
Weight Decreased Other Serious 6/1/2000 Female 115 lb 11/3/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 3/1/2008 Female 10/29/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 260 lb 11/10/2008 United States
Primary
Concomitant
Somnolence 9/18/2008 54 Female 10/31/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2000 Female 115 lb 11/12/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/1/2008 Female 235 lb 11/11/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 Female 110 lb 12/1/2008 Lawyer United States
Primary
Concomitant
Meniscus Lesion Other Serious 3/3/2007 43 Female 291 lb 12/3/2008 United States
Primary
Concomitant

Drug Data