Clonazepam combined with Pregabalin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Impulsive Behaviour Required Intervention 1/1/2006 39 Male 8/4/2006 Pharmacist United Kingdom
Primary
Concomitant
Overdose Death 9/26/2006 52 Male 190 lb 10/23/2006 United States
Primary
Concomitant
Fatigue Life Threatening 9/9/2006 60 Male 164 lb 10/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 55 Male 10/26/2006 Consumer United States
Primary
Concomitant
Respiratory Rate Decreased Life Threatening 9/3/2006 55 Female 142 lb 11/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Required Intervention 8/24/2006 55 Female 142 lb 11/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/6/2006 63 Male 12/1/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hepatotoxicity Death 12/15/2006 75 Female 1/2/2007 Physician Chile
Primary
Secondary
Platelet Count Decreased Disability 1/4/2007 81 Female 126 lb 1/9/2007 Pharmacist United States
Primary
Concomitant
Hepatic Failure Death 12/15/2006 Female 1/19/2007 Physician Chile
Primary
Secondary
Treatment Noncompliance Life Threatening 9/3/2006 55 Female 142 lb 2/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Life Threatening 9/1/2006 60 Male 164 lb 4/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
Neutropenia 1/1/2007 22 Female 6/12/2007 Physician Chile
Primary
Concomitant
Thrombosis In Device Death 5/18/2007 77 Female 6/19/2007 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 5/24/2007 60 Male 208 lb 7/31/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/17/2007 60 Male 208 lb 8/21/2007 United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 7/1/2007 58 Female 9/10/2007 United Kingdom
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 7/1/2005 Female 155 lb 12/14/2007 Physician United States
Primary
Concomitant
Lethargy 7/4/2007 Male 43 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2006 46 Female 1/18/2008 United States
Primary
Secondary
Cardio-respiratory Arrest Death 2/1/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 46 Female 1/25/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 46 Female 1/31/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 46 Female 2/13/2008 Physician United States
Primary
Secondary
Drug Ineffective 11/1/2007 Female 190 lb 3/14/2008 United States
Primary
Concomitant
Smear Cervix Abnormal 3/10/2007 Female 178 lb 3/15/2008 Physician United States
Primary
Concomitant
Periarthritis 1/25/2008 Female 3/15/2008 United States
Primary
Concomitant
Stomatitis Female 200 lb 3/15/2008 United States
Primary
Concomitant
Fatigue Female 200 lb 3/15/2008 United States
Primary
Concomitant
Cardio-respiratory Arrest Death 3/19/2008 Physician United States
Primary
Secondary
Weight Increased Other Serious 3/1/2008 Female 135 lb 4/2/2008 Physician Canada
Primary
Concomitant
Muscular Weakness Hospitalization 5/1/2007 77 Female 4/26/2008 Pharmacist United States
Primary
Secondary
Rash Morbilliform Hospitalization 4/4/2008 78 Female 5/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Swelling 1/1/2008 Male 201 lb 6/13/2008 United States
Primary
Concomitant
Convulsion Hospitalization Female 6/16/2008 Pharmacist Canada
Primary
Concomitant
Respiratory Arrest Other Serious 46 Female 6/19/2008 Physician United States
Primary
Secondary
Tooth Extraction Other Serious 2/1/2008 Female 160 lb 6/19/2008 Canada
Primary
Concomitant
Drug Ineffective 11/1/2007 47 Female 190 lb 6/23/2008 United States
Primary
Concomitant
Angioedema Other Serious 8/26/2007 40 Female 6/20/2008 Pharmacist United States
Primary
Concomitant
Convulsion Hospitalization Female 170 lb 7/3/2008 Physician Canada
Primary
Concomitant
Rash Morbilliform Hospitalization 4/4/2008 78 Female 7/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Rate Decreased Life Threatening 8/24/2006 55 Female 142 lb 7/2/2008 Physician United States
Primary
Secondary
Concomitant
Rash Morbilliform Hospitalization 4/4/2008 78 Female 7/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria 9/27/2007 48 Female 181 lb 9/28/2007 Consumer United States
Primary
Concomitant
Urticaria 9/27/2007 48 Female 181 lb 8/13/2008 Consumer United States
Primary
Concomitant
Respiratory Depression Hospitalization 1/1/2006 50 Female 8/18/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 1/1/2006 46 Female 8/18/2008 Physician United States
Primary
Secondary
Concomitant
Tremor 7/20/2008 Male 281 lb 8/29/2008 United States
Primary
Concomitant
Pruritus Other Serious 2/10/2008 28 Female 9/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus Other Serious 2/10/2008 28 Female 9/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection 1/25/2008 Female 145 lb 9/12/2008 United States
Primary
Concomitant
Drug Ineffective 8/1/2007 Female 240 lb 9/12/2008 United States
Primary
Concomitant
Rash Macular 6/22/2008 Female 181 lb 9/12/2008 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Female 250 lb 9/13/2008 United States
Primary
Concomitant
Pruritus Other Serious 2/10/2008 28 Female 9/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinusitis Other Serious 7/12/2008 Female 156 lb 10/1/2008 Canada
Primary
Concomitant
Sinusitis Other Serious 7/12/2008 Female 156 lb 11/7/2008 Canada
Primary
Concomitant
Somnolence 6/20/2008 Female 175 lb 12/4/2008 Other Health Professional United States
Primary
Concomitant
Intentional Drug Misuse Death 1/1/2007 21 Female 12/22/2008 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 21 Female 12/29/2008 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 1/1/2007 38 Female 12/29/2008 Physician United States
Primary
Secondary
Completed Suicide Death 38 Female 12/31/2008 Pharmacist United States
Primary
Secondary
Road Traffic Accident Other Serious 1/1/2008 1/6/2009 Physician France
Primary
Concomitant
Intentional Drug Misuse Death 1/1/2007 38 Female 1/6/2009 United States
Primary
Secondary
Intentional Drug Misuse Death 1/1/2007 21 Female 1/6/2009 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 21 Female 1/15/2009 United States
Primary
Secondary
Completed Suicide Death 38 Female 1/16/2009 United States
Primary
Secondary
Drug Abuse Death 21 Female 1/23/2009 Physician United States
Primary
Secondary
Poisoning Death 21 Female 1/19/2009 Physician United States
Primary
Secondary
Poisoning Deliberate Death 38 Female 1/19/2009 Physician United States
Primary
Secondary
Completed Suicide Other Serious 1/30/2009 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 1/1/2007 38 Female 1/30/2009 Physician United States
Primary
Secondary
Death Death 1/1/2007 21 Female 2/2/2009 Pharmacist United States
Primary
Secondary
Death Death 1/1/2007 38 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Diffuse Large B-cell Lymphoma Stage Iv Other Serious 10/1/2008 Female 154 lb 2/6/2009 Consumer Chile
Primary
Concomitant
Overdose Other Serious 12/29/2008 65 Female 2/11/2009 United States
Primary
Secondary
Concomitant
Obsessive Thoughts 9/11/2008 25 Male 220 lb 9/15/2008 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 1/1/2007 38 Female 3/3/2009 Physician United States
Primary
Secondary
Oedema Peripheral Life Threatening 9/1/2006 60 Male 164 lb 3/20/2009 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2006 46 Female 3/20/2009 Physician United States
Primary
Secondary
Somnolence Life Threatening 1/16/2009 52 Male 3/24/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Completed Suicide Death 38 Female 3/31/2009 Physician United States
Primary
Secondary
Food Poisoning Hospitalization 2/7/2009 Female 4/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Intrathecal Pump Insertion Hospitalization 2/23/2009 33 Male 115 lb 5/4/2009 Physician Italy
Primary
Concomitant
Intrathecal Pump Insertion Hospitalization 2/23/2009 33 Male 115 lb 5/21/2009 Physician Italy
Primary
Concomitant
Completed Suicide Other Serious 5/27/2009 Other Health Professional United States
Primary
Secondary
Completed Suicide Other Serious 5/27/2009 Other Health Professional United States
Primary
Secondary
Lethargy 7/4/2007 4 Male 43 lb 6/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Lipodystrophy Acquired Other Serious Female 6/15/2009 Physician France
Primary
Concomitant
Intrathecal Pump Insertion Hospitalization 2/23/2009 33 Male 115 lb 6/26/2009 Physician Italy
Primary
Concomitant
Drug Ineffective Other Serious 20 7/1/2009 Physician Czech Republic
Primary
Secondary
Completed Suicide Death 38 Female 7/1/2009 Physician United States
Primary
Secondary
Food Poisoning Hospitalization 2/6/2009 Female 7/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/14/2009 49 Male 7/21/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 6/27/2009 41 Female 8/5/2009 Physician United States
Primary
Concomitant
Overdose Other Serious 12/29/2008 Female 86 lb 8/11/2009 France
Primary
Secondary
Concomitant
Pruritus 10/1/2008 Female 8/22/2009 United States
Primary
Concomitant
Injection Site Extravasation 8/1/2007 Female 240 lb 9/12/2009 United States
Primary
Concomitant
Vomiting Other Serious 8/1/2007 65 Female 9/21/2009 Lawyer United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/8/2009 56 Male 10/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Overdose Hospitalization 10/12/2009 68 10/28/2009 Physician United Kingdom
Primary
Secondary
Pulmonary Oedema Hospitalization 6/14/2009 49 Male 10/29/2009 Other Health Professional France
Primary
Secondary
Concomitant
Overdose Hospitalization 10/12/2009 68 Female 11/10/2009 Physician
Primary
Secondary
Concomitant
Drug Abuse Other Serious 50 Female 11/23/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Overdose Hospitalization 10/12/2009 68 Female 11/13/2009 Physician United Kingdom
Primary
Secondary
Headache Other Serious 50 Female 11/25/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Symptom Masked Other Serious 50 Female 12/2/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2007 65 Female 1/11/2010 Lawyer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 61 Female 1/5/2010 Consumer United Kingdom
Primary
Concomitant
Respiratory Arrest Death 1/1/2008 47 Female 1/15/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 47 Female 1/16/2010 Physician United States
Primary
Secondary
Treatment Noncompliance Other Serious 44 Female 1/26/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2008 160 lb 2/4/2010 Physician United States
Primary
Concomitant
Post Laminectomy Syndrome Other Serious 1/1/2004 56 Male 2/7/2010 Physician Spain
Primary
Concomitant
Respiratory Arrest Death 1/1/2008 47 Female 2/1/2010 Physician United States
Primary
Secondary
Transient Ischaemic Attack Hospitalization 11/1/2008 59 Female 2/11/2010 Physician United Kingdom
Primary
Concomitant
Drug Abuse Death 47 Female 2/22/2010
Primary
Secondary
Obsessive Thoughts 9/11/2008 25 Male 220 lb 9/15/2008 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/8/2009 56 Male 3/1/2010 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Hesitation 10/12/2008 53 Male 292 lb 11/13/2008 Other Health Professional United States
Primary
Concomitant
Death Death 1/1/2008 47 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Acute Hepatic Failure Other Serious Female 4/14/2010 Physician United States
Primary
Concomitant
Tendon Rupture Other Serious 1/1/2009 51 Female 154 lb 4/15/2010 Brazil
Primary
Concomitant
Hypoglycaemia Hospitalization 3/2/2010 37 Female 179 lb 4/9/2010 Consumer United States
Primary
Concomitant
Autoimmune Hepatitis Other Serious 4/1/2010 50 Female 4/30/2010 Physician United States
Primary
Concomitant
Urethrotomy Other Serious 36 Male 6/10/2010 Pharmacist United Kingdom
Primary
Concomitant
Overdose Hospitalization 10/12/2009 68 Female 7/9/2010 Physician United Kingdom
Primary
Secondary
Upper Gastrointestinal Haemorrhage Hospitalization 2/21/2010 63 Male 7/15/2010 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Overdose Hospitalization 10/12/2009 68 Female 7/20/2010 Physician United Kingdom
Primary
Secondary
Pneumonia Aspiration Hospitalization 7/13/2009 41 Female 7/28/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased 12/1/2006 49 Female 116 lb 8/2/2010 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/1/2010 61 Male 287 lb 8/10/2010 Physician France
Primary
Concomitant
Encephalopathy Hospitalization 10/30/2009 39 Male 8/18/2010 Other Health Professional France
Primary
Concomitant
Peripheral Ischaemia Hospitalization 30 Male 9/14/2010 Physician Sweden
Primary
Concomitant
Overdose Hospitalization 10/12/2009 68 Female 9/16/2010 Physician United Kingdom
Primary
Secondary
Suicide Attempt Other Serious 12/10/2009 20 Female 131 lb 9/16/2010 Physician Peru
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2008 47 Female 9/16/2010 Physician United States
Primary
Secondary
Rash Erythematous Other Serious 9/13/2010 60 Female 220 lb 9/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 69 Female 10/1/2010 Physician Belgium
Primary
Secondary
Concomitant
Pain Other Serious 11/1/2008 59 Female 155 lb 9/30/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2010 38 Male 10/26/2010 Consumer United States
Primary
Concomitant
Subdural Haemorrhage Hospitalization 9/13/2010 40 Female 11/22/2010 Other Health Professional Czech Republic
Primary
Concomitant
Subdural Haemorrhage Hospitalization 9/13/2010 40 Female 12/3/2010 Other Health Professional Czech Republic
Primary
Concomitant
Injection Site Abscess Other Serious 9/7/2010 48 Male 284 lb 12/10/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 11/4/2009 12/13/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 11/4/2009 12/13/2010 Consumer United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 1/1/2007 12/14/2010 Physician United States
Primary
Concomitant
Overdose Hospitalization 10/12/2009 68 10/28/2009 Physician United Kingdom
Primary
Secondary
Suicide Attempt Other Serious 12/10/2009 20 Female 131 lb 12/24/2009 Physician Peru
Primary
Secondary
Concomitant

Drug Data