Clonazepam combined with Phenobarbital Tab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Other Serious 10/2/2004 65 Female 1/23/2006 Physician United States
Primary
Secondary
Concomitant
Infusion Related Reaction Death 2/7/2006 Other Health Professional Netherlands
Primary
Concomitant
Ventricular Extrasystoles Other Serious 2/7/2006 Physician Netherlands
Primary
Concomitant
Neonatal Disorder Other Serious 2/7/2006 Physician Netherlands
Primary
Concomitant
Ventricular Extrasystoles Other Serious 2/7/2006 Physician Netherlands
Primary
Concomitant
Infusion Related Reaction Other Serious 2/7/2006 Physician Netherlands
Primary
Concomitant
Tachycardia Other Serious 2/7/2006 Physician Netherlands
Primary
Concomitant
Bladder Cancer Required Intervention 10/1/2005 42 Male 110 lb 4/4/2006 Physician Japan
Primary
Concomitant
Granulocytopenia Required Intervention 10/9/2005 29 Male 155 lb 6/20/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 31 Female 7/28/2006 Physician Japan
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 6/29/2003 1 Male 13 lb 11/7/2006 Physician Japan
Primary
Concomitant
Metrorrhagia Female 7/7/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 5/27/2005 3 Male 29 lb 12/14/2006 Physician Japan
Primary
Concomitant
Initial Insomnia 7/6/2006 45 Male 148 lb 10/11/2006 Consumer United States
Primary
Concomitant
Tremor Other Serious 6/1/2006 Male 170 lb 1/25/2007 Consumer United States
Primary
Concomitant
Restlessness Death 5/21/2003 69 Male 2/2/2007 Other Health Professional Japan
Primary
Concomitant
Hypersomnia 57 Male 3/1/2007 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Death 1/1/2004 45 Unknown 3/22/2007 Pharmacist United States
Primary
Secondary
Pseudolymphoma Other Serious Male 4/11/2007 Physician France
Primary
Concomitant
Nervous System Disorder Other Serious 1/1/2007 38 Male 4/27/2007 Consumer Brazil
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 4/28/2004 Female 5/8/2007 Lawyer United States
Primary
Secondary
Nervous System Disorder Other Serious 1/1/2007 38 Male 6/4/2007 Consumer Brazil
Primary
Secondary
Concomitant
Malabsorption Other Serious 8/1/2006 Female 6/7/2007 Physician France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 7/5/2005 Female 93 lb 6/13/2007 Lawyer United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 12/6/2003 55 Male 6/18/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/6/2003 55 Male 6/25/2007 Other Health Professional Japan
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 12/6/2003 55 Male 6/26/2007 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 7/5/2005 Female 93 lb 7/10/2007 Lawyer United States
Primary
Secondary
Concomitant
Status Epilepticus Other Serious Female 7/26/2007 Consumer United States
Primary
Secondary
Concomitant
Epilepsy Hospitalization 13 Male 8/15/2007 Japan
Primary
Concomitant
Status Epilepticus Other Serious Female 8/22/2007 United States
Primary
Secondary
Concomitant
Epilepsy Hospitalization 13 Male 8/28/2007 Japan
Primary
Concomitant
Status Epilepticus Hospitalization 6/29/2003 1 Male 13 lb 9/7/2007 Physician Japan
Primary
Concomitant
Sepsis Death 3/30/2006 5 Male 33 lb 10/17/2007 Physician Japan
Primary
Concomitant
Metabolic Acidosis Other Serious 0 Male 11/1/2007 Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 0 Male 11/13/2007 Japan
Primary
Secondary
Concomitant
Peripheral Paralysis Other Serious 12/1/2006 Male 12/6/2007 Consumer United States
Primary
Concomitant
Prostration Other Serious 1/1/2007 38 Male 12/17/2007 Consumer Brazil
Primary
Secondary
Concomitant
Petit Mal Epilepsy Other Serious 53 Male 1/10/2008 Other Health Professional France
Primary
Concomitant
Lethargy 7/4/2007 Male 43 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 0 Male 2/15/2008 Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 11 Male 3/25/2008 Physician Japan
Primary
Secondary
Concomitant
Fall Other Serious 2/13/2008 47 Female 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Somnolence 9/21/2007 Female 145 lb 4/11/2008 Consumer United States
Primary
Secondary
Concomitant
Femoral Neck Fracture Hospitalization 11/10/2006 5 Male 33 lb 4/8/2008 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 2/1/2008 1 Female 22 lb 5/1/2008 Other Health Professional France
Primary
Secondary
Hepatic Failure Life Threatening 2/13/2008 1 Female 5/14/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 16 Female 6/3/2008 Japan
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 16 Female 6/13/2008 Japan
Primary
Secondary
Concomitant
Syncope Other Serious 7/1/2006 Female 130 lb 6/17/2008 United States
Primary
Concomitant
Respiratory Arrest Other Serious 45 6/19/2008 Physician United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 7/9/2008 Other Health Professional Netherlands
Primary
Secondary
Overdose Other Serious 30 Male 7/4/2008 United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 7/3/2008 Female 7/16/2008 United States
Primary
Concomitant
Swelling Face Other Serious 7/3/2008 Female 7/23/2008 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 11/1/2007 16 Female 62 lb 8/15/2008 Physician Japan
Primary
Secondary
Concomitant
Petit Mal Epilepsy Other Serious 60 Male 8/15/2008 France
Primary
Concomitant
Urine Abnormality Other Serious 10/4/2007 Female 90 lb 9/2/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 75 Female 9/19/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Urine Abnormality Other Serious 10/4/2007 Female 90 lb 9/25/2008 Consumer United States
Primary
Concomitant
Sopor Other Serious 10/17/2008 29 Female 10/24/2008 Physician Brazil
Primary
Secondary
Femoral Neck Fracture Hospitalization 11/10/2006 5 Male 33 lb 10/27/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 10/11/2008 Female 137 lb 10/29/2008 Consumer Brazil
Primary
Concomitant
Headache Other Serious 1/1/2008 Male 234 lb 11/24/2008 Consumer Brazil
Primary
Concomitant
Epilepsy Other Serious 6/2/2005 1 Male 22 lb 3/6/2009 Italy
Primary
Concomitant
Vision Blurred Other Serious 3 Male 4/28/2009 Other Health Professional Germany
Primary
Secondary
Lethargy 7/4/2007 4 Male 43 lb 6/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/19/2007 2 Male 13 lb 6/8/2009 Physician Japan
Primary
Concomitant
Petit Mal Epilepsy Other Serious 4/1/2009 Male 6/16/2009 Consumer Argentina
Primary
Concomitant
Anaemia Hospitalization 6/22/2009 Female 129 lb 12/30/2009 Physician United States
Primary
Concomitant
Hypotension Required Intervention 0 Female 12/22/2009 Physician India
Primary
Concomitant
Multiple Drug Overdose Death 53 Male 200 lb 1/22/2010 Physician United States
Primary
Secondary
Pancreatitis Hospitalization 70 Female 2/4/2010
Primary
Secondary
Grand Mal Convulsion Hospitalization 40 Female 2/4/2010
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 5/21/2004 67 Male 2/4/2010
Primary
Secondary
Concomitant
Ischaemic Cerebral Infarction Life Threatening 6 Male 53 lb 2/5/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/19/2010 17 Male 4/7/2010 Physician Japan
Primary
Secondary
Restlessness Other Serious 44 Female 4/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Lethargy Other Serious 7/13/2010 23 Female 7/23/2010 United States
Primary
Concomitant
Hyperammonaemic Encephalopathy Other Serious 5 Male 9/9/2010
Primary
Secondary
Lethargy Other Serious 7/13/2010 23 Female 9/8/2010 United States
Primary
Concomitant
Somnolence Hospitalization 10/11/2010 0 Male 10/27/2010 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 30 Female 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 30 Female 11/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 28 Female 11/30/2010 Other Health Professional Iran (Islamic Republic Of)
Primary
Secondary
Somnolence Hospitalization 28 Female 11/30/2010 Other Health Professional Iran (Islamic Republic Of)
Primary
Secondary
Somnolence Hospitalization 28 Female 11/30/2010 Other Health Professional Iran (Islamic Republic Of)
Primary
Secondary
Transaminases Increased Other Serious 3 Female 12/3/2010 Other Health Professional Spain
Primary
Concomitant
Completed Suicide Death 36 Female 1/20/2011 United States
Primary
Secondary
Off Label Use Other Serious 10 Female 5/5/2011 Germany
Primary
Concomitant
Status Epilepticus Death 10 Female 5/19/2011 Physician Germany
Primary
Concomitant
Lip Dry Hospitalization Female 5/27/2011 Consumer Brazil
Primary
Concomitant
Multiple Drug Overdose Hospitalization 45 Female 5/31/2011 Other Health Professional Brazil
Primary
Secondary
Acute Hepatic Failure Death 7/14/2010 7 Female 5/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization Female 143 lb 6/13/2011 Consumer Brazil
Primary
Secondary
Concomitant
Bradycardia Hospitalization 75 Female 6/14/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Gliosis Other Serious 5 Male 6/13/2011 Other Health Professional India
Primary
Concomitant
Neutropenia Hospitalization 75 Female 6/28/2011 Pharmacist United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 75 Female 7/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pupillary Reflex Impaired Life Threatening 30 Female 6/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/1/2011 47 Female 8/4/2011 Consumer Brazil
Primary
Concomitant
Toxicity To Various Agents Life Threatening 24 Male 7/29/2011 Other Health Professional India
Primary
Secondary
Grand Mal Convulsion Hospitalization 75 Female 8/3/2011 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious Male 8/12/2011 Other Health Professional Germany
Primary
Concomitant
Partial Seizures With Secondary Generalisation Other Serious 25 Male 8/15/2011 Other Health Professional Japan
Primary
Concomitant
Hyperventilation Other Serious 2/8/2008 51 Male 154 lb 8/16/2011 Consumer Brazil
Primary
Concomitant
Ammonia Increased Hospitalization Male 8/18/2011 Other Health Professional Lebanon
Primary
Secondary
Hyporeflexia Hospitalization Male 8/18/2011 Other Health Professional Lebanon
Primary
Secondary
Renal Tubular Disorder Hospitalization 8 Female 51 lb 8/26/2011 Physician Japan
Primary
Concomitant
Hypothermia Hospitalization 5/3/2011 64 Male 9/2/2011 Physician France
Primary
Concomitant
Gastrointestinal Infection Other Serious Male 137 lb 9/7/2011 Consumer Brazil
Primary
Concomitant
Intentional Drug Misuse Other Serious 9/3/2011 41 Female 9/13/2011 Physician Italy
Primary
Secondary
Nervousness Hospitalization 6/8/2011 36 Female 9/13/2011 Consumer Brazil
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/7/2011 54 Female 9/13/2011 United States
Primary
Concomitant
Epilepsy Hospitalization 6/8/2011 36 Female 9/19/2011 Consumer Brazil
Primary
Concomitant
Status Epilepticus Death 7/14/2010 7 Female 9/19/2011 Other Health Professional France
Primary
Secondary
Concomitant
Tongue Disorder Female 9/22/2011 United States
Primary
Concomitant
Intentional Drug Misuse 12/1/2009 59 Female 240 lb 9/22/2011 Consumer United States
Primary
Concomitant
Status Epilepticus Hospitalization 7/1/2011 2 Male 9/22/2011 Physician Ireland
Primary
Concomitant
Tremor 6/22/2011 54 Female 138 lb 9/28/2011 Other Health Professional United States
Primary
Concomitant
Myoclonus Other Serious Male 5 lb 10/4/2011 Physician United States
Primary
Secondary
Nervousness Hospitalization 6/8/2011 36 Female 10/4/2011 Consumer Brazil
Primary
Concomitant
Oedema Peripheral Hospitalization 6/8/2011 36 Female 10/11/2011 Consumer Brazil
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2007 54 Male 220 lb 10/19/2011 Consumer Brazil
Primary
Secondary
Concomitant
Psychomotor Retardation Other Serious Male 10/24/2011 Other Health Professional India
Primary
Secondary
Concomitant
Epilepsy Hospitalization 10/21/2009 10/25/2011 China
Primary
Concomitant
Interacting
Propofol Infusion Syndrome Death 7 Male 61 lb 11/3/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Other Serious 30 Female 11/4/2011 Other Health Professional Japan
Primary
Secondary
Oedema Peripheral Other Serious 6/8/2011 36 Female 11/4/2011 Consumer Brazil
Primary
Concomitant
Fatigue Other Serious 55 Unknown 10/10/2011 Pharmacist United States
Primary
Concomitant
Convulsion Hospitalization 5/10/2010 15 Male 11/11/2011 Physician Japan
Primary
Concomitant
Dyspnoea Other Serious 30 Female 11/15/2011 Other Health Professional Japan
Primary
Secondary
Bradyarrhythmia Other Serious Male 11/23/2011 Physician Japan
Primary
Concomitant
Drug Interaction Other Serious 1/1/2009 30 Male 11/23/2011 Other Health Professional China
Primary
Concomitant
Interacting
Dizziness Hospitalization 6/8/2011 36 Female 11/23/2011 Consumer Brazil
Primary
Concomitant
Blood Pressure Decreased Other Serious 1/1/2011 43 Male 85 lb 11/28/2011 Physician Japan
Primary
Concomitant
Renal Tubular Acidosis Other Serious 2 Female 12/7/2011 Physician Taiwan, Province Of China
Primary
Concomitant
Cutaneous Lupus Erythematosus Hospitalization 6/25/2009 28 Female 12/14/2011 Physician France
Primary
Concomitant
Tonic Clonic Movements Hospitalization 5/10/2010 15 Male 12/22/2011 Physician Japan
Primary
Concomitant
Bradyarrhythmia Other Serious 4/19/2011 43 Male 85 lb 12/28/2011 Physician Japan
Primary
Concomitant
Completed Suicide Death 1/1/2010 45 Female 12/23/2011 Physician United States
Primary
Secondary
Completed Suicide Death 45 Female 1/4/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 45 Female 1/4/2012 Physician United States
Primary
Secondary
Epilepsy Life Threatening 30 Male 12/30/2011 Other Health Professional United States
Primary
Secondary
Renal Tubular Acidosis Other Serious 2 Female 1/6/2012 Physician Taiwan, Province Of China
Primary
Concomitant
Sudden Unexplained Death In Epilepsy Death 1/15/2011 21 Female 165 lb 1/9/2012 Physician France
Primary
Concomitant
Toxicity To Various Agents Death 45 Female 1/11/2012 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2010 45 Female 1/13/2012 Physician United States
Primary
Secondary
Poisoning Death 45 Female 1/9/2012 Physician United States
Primary
Secondary
Overdose Death 45 Female 1/23/2012 Physician United States
Primary
Secondary

Drug Data