Clonazepam combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Arrest Death 37 Male 2/7/2006 Pharmacist United States
Primary
Secondary
Rib Fracture Other Serious Male 2/24/2006 Canada
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/7/2005 56 Male 304 lb 11/10/2005 United States
Primary
Secondary
Pneumothorax Hospitalization 12/13/2005 53 Female 131 lb 3/28/2006 Other Health Professional Canada
Primary
Concomitant
Therapeutic Response Unexpected 1/1/2005 72 Male 1/23/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 1/1/2005 72 Male 1/31/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Peripheral Vascular Disorder Death 12/1/2003 69 Female 214 lb 4/19/2006 Lawyer United States
Primary
Concomitant
Shoulder Pain Other Serious Male 4/10/2006 Canada
Primary
Concomitant
Shock Other Serious 2/1/2006 23 Male 170 lb 4/11/2006 Consumer Thailand
Primary
Secondary
Concomitant
Panic Attack Other Serious 1/1/2006 Female 145 lb 4/20/2006 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 8/29/2001 58 Female 130 lb 5/8/2006 Lawyer United States
Primary
Concomitant
Shock Other Serious 2/1/2006 23 Male 170 lb 4/28/2006 Physician Thailand
Primary
Secondary
Concomitant
Shock Other Serious 2/1/2006 23 Male 170 lb 5/12/2006 Physician Thailand
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 3/17/2006 79 Male 423 lb 5/16/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance 4/23/2006 55 Female 4/23/2006 Pharmacist United States
Primary
Concomitant
Shoulder Pain Other Serious Male 5/30/2006 Canada
Primary
Concomitant
Somnolence Life Threatening 4/12/2006 55 Female 165 lb 6/2/2006 Physician France
Primary
Secondary
Concomitant
Therapeutic Response Unexpected 1/1/2005 72 Male 4/6/2006 Consumer United States
Primary
Concomitant
Respiratory Failure Death 2/23/2006 82 Female 139 lb 6/21/2006 Other Health Professional France
Primary
Concomitant
Skin Ulcer Hospitalization 5/9/2006 69 Male 6/28/2006 Physician France
Primary
Concomitant
Skin Ulcer Hospitalization 5/9/2006 69 Male 6/28/2006 Physician France
Primary
Concomitant
Vomiting Hospitalization 5/26/2006 45 Male 7/3/2006 Other Health Professional France
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 5/9/2006 69 Male 7/14/2006 Physician France
Primary
Concomitant
Drug Ineffective 42 Female 6/6/2006 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/8/2004 47 Female 118 lb 8/28/2006 Physician Canada
Primary
Secondary
Concomitant
Respiratory Failure Death 35 Female 9/19/2006 Physician United States
Primary
Secondary
Haemorrhage Other Serious 9/8/2006 42 Female 9/21/2006 Pharmacist Canada
Primary
Concomitant
Somnolence Other Serious 58 Male 9/22/2006 Japan
Primary
Concomitant
Jaundice Other Serious 8/1/2006 56 Male 220 lb 9/22/2006 Pharmacist Netherlands
Primary
Concomitant
Nausea Hospitalization 9/25/2006 44 Male 283 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 6/1/2006 Male 145 lb 11/8/2006 Consumer United States
Primary
Secondary
Concomitant
Poisoning Death 35 11/17/2006 Physician United States
Primary
Secondary
Vomiting Death 11/12/2002 24 Male 11/20/2006 United States
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 1/1/2005 35 11/22/2006 Physician United States
Primary
Secondary
Hypotension Hospitalization 8/10/2006 84 Male 164 lb 11/27/2006 Other Health Professional United States
Primary
Concomitant
Nicotine Dependence 55 Female 12/20/2006 Consumer United States
Primary
Concomitant
Therapy Regimen Changed Life Threatening 9/1/2006 60 Male 164 lb 12/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 7/31/2006 44 Male 12/14/2006 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 12/16/2006 Male 167 lb 12/29/2006 Canada
Primary
Concomitant
Suicidal Ideation Other Serious 11/7/2006 Male 220 lb 1/5/2007 Physician Canada
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2006 Female 115 lb 1/10/2007 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 6/12/2006 Female 120 lb 1/16/2007 Consumer Canada
Primary
Concomitant
Intentional Overdose Death 11/12/2002 Male 1/22/2007 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Life Threatening 1/1/2005 35 1/24/2007 United States
Primary
Secondary
Completed Suicide Death 35 Unknown 1/25/2007 Physician United States
Primary
Secondary
Malaise Hospitalization 1/17/2007 Female 2/5/2007 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Death 12/16/2006 Male 167 lb 2/21/2007 Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 12/24/2006 67 Female 2/13/2007 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 2/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 4/28/2004 52 Female 2/27/2007 Lawyer United States
Primary
Secondary
Malaise Hospitalization 1/17/2007 Female 2/28/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 1/1/2007 Female 3/15/2007 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization Female 3/16/2007 Physician United States
Primary
Concomitant
Suicide Attempt Other Serious 4/28/2004 Female 3/23/2007 Lawyer United States
Primary
Secondary
Intentional Overdose Death 11/12/2002 Male 3/27/2007 Lawyer United States
Primary
Secondary
Concomitant
Pruritus Other Serious 1/23/2007 74 Male 260 lb 1/31/2007 Pharmacist United States
Primary
Concomitant
Hypokalaemia Hospitalization 3/1/2007 Female 136 lb 4/2/2007 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 6/12/2006 Female 120 lb 4/12/2007 Consumer Canada
Primary
Concomitant
Suicide Attempt Other Serious 4/28/2004 Female 5/8/2007 Lawyer United States
Primary
Secondary
Surgery Other Serious 1/1/2007 Male 168 lb 5/30/2007 Physician United States
Primary
Concomitant
Blood Glucose Increased 2/14/2007 58 Male 230 lb 4/23/2007 Consumer United States
Primary
Secondary
Concomitant
Rhinorrhoea 2/14/2007 66 Female 5/17/2007 United States
Primary
Concomitant
Weight Increased 10/1/2006 34 Female 210 lb 5/11/2007 Physician United States
Primary
Secondary
Concomitant
Skin Infection Death 6/11/2007 Male 6/27/2007 Pharmacist United States
Primary
Concomitant
Hepatitis Toxic Hospitalization 4/3/2007 48 Male 165 lb 7/3/2007 Other Health Professional France
Primary
Concomitant
Death Death 6/2/2007 60 Male 6/27/2007 Pharmacist United States
Primary
Concomitant
Restless Legs Syndrome Other Serious 6/25/2007 Female 150 lb 7/10/2007 Consumer United States
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 1/1/2007 Female 7/30/2007 Physician United States
Primary
Concomitant
Multiple Myeloma Death 6/2/2007 60 Male 7/31/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 5/29/2007 17 Female 8/10/2007 Consumer France
Primary
Secondary
Concomitant
Tremor Hospitalization Male 8/10/2007 Consumer Argentina
Primary
Concomitant
Skin Striae Hospitalization 5/31/2007 17 Female 8/13/2007 Physician France
Primary
Secondary
Concomitant
Application Site Reaction Disability 4/27/2007 64 Female 8/22/2007 Physician Switzerland
Primary
Concomitant
Pleural Effusion Other Serious 6/4/2007 68 Female 8/30/2007 Physician Brazil
Primary
Concomitant
Premature Baby Other Serious 0 Female 5 lb 9/4/2007
Primary
Secondary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/5/2007 United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 6/5/2007 51 Female 280 lb 8/31/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 1/1/2007 Female 9/6/2007 Physician United States
Primary
Concomitant
Nausea Other Serious 8/6/2007 Female 160 lb 9/7/2007 Consumer United States
Primary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/11/2007 United States
Primary
Concomitant
Pleural Effusion Other Serious 6/4/2007 68 Female 9/12/2007 Physician Brazil
Primary
Concomitant
Stomatitis Other Serious 11/1/2006 47 Female 10/18/2007 Other Health Professional Canada
Primary
Concomitant
Respiratory Arrest Other Serious 35 10/29/2007 Physician United States
Primary
Secondary
Death Death 5/23/2007 Male 183 lb 11/2/2007 United States
Primary
Concomitant
Road Traffic Accident Other Serious 57 Male 11/28/2007
Primary
Secondary
Concomitant
Drug Toxicity Death 74 Male 1/15/2008 Physician United States
Primary
Secondary
Serotonin Syndrome Death 48 Male 1/10/2008 Physician Canada
Primary
Secondary
Concomitant
Dental Caries Other Serious 12/2/2007 Female 1/18/2008 Pharmacist Canada
Primary
Concomitant
Respiratory Arrest Death 1/1/2006 46 Female 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 74 Male 1/22/2008 Physician United States
Primary
Secondary
Serotonin Syndrome Death 48 Male 1/23/2008 Physician Canada
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 203 lb 1/30/2008 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 8/6/2007 Female 160 lb 1/30/2008 Consumer United States
Primary
Concomitant
Post Procedural Discharge Other Serious 9/26/2007 Female 2/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 2/5/2008 United States
Primary
Concomitant
Respiratory Arrest Death 46 Female 1/31/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 33 Male 1/31/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 43 Male 1/31/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 43 Male 2/5/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 46 Female 2/13/2008 Physician United States
Primary
Secondary
Serotonin Syndrome Death 2/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Injury Other Serious Female 249 lb 2/22/2008 United States
Primary
Concomitant
Serotonin Syndrome Death 3/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Death 48 Male 2/21/2008 Canada
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2007 48 Male 3/7/2008 Consumer Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 2/1/2008 Female 214 lb 3/11/2008 United States
Primary
Concomitant
Completed Suicide Death 3/19/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 3/19/2008 Physician United States
Primary
Secondary
Weight Increased Other Serious 1/1/2007 Female 203 lb 3/21/2008 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 3/26/2008 Physician United States
Primary
Secondary
Completed Suicide Death 3/26/2008 Physician United States
Primary
Secondary
Completed Suicide Death 3/28/2008 Physician United States
Primary
Secondary
Serotonin Syndrome Death 48 Male 4/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Injury Other Serious 10/1/2007 Female 249 lb 4/25/2008 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 192 lb 5/15/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 150 lb 5/16/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/1/2004 Female 260 lb 6/9/2008 Consumer United States
Primary
Concomitant
Substance Abuse Other Serious 44 Male 6/11/2008 Physician Canada
Primary
Secondary
Substance Abuse Other Serious 50 Male 6/11/2008 Physician Canada
Primary
Secondary
Accidental Exposure 5/7/2008 Female 210 lb 6/13/2008 Consumer United States
Primary
Concomitant
Death Death 5/23/2007 Male 183 lb 6/18/2008 United States
Primary
Concomitant
Respiratory Arrest Other Serious 33 Male 6/19/2008 Physician United States
Primary
Secondary
Respiratory Arrest Other Serious 43 Male 6/19/2008 Physician United States
Primary
Secondary
Respiratory Arrest Other Serious 46 Female 6/19/2008 Physician United States
Primary
Secondary
Respiratory Arrest Other Serious 74 Male 6/19/2008 Physician United States
Primary
Secondary
Serotonin Syndrome Death 48 Male 6/24/2008 Canada
Primary
Concomitant
Interacting
Myalgia Hospitalization 1/1/2008 Male 6/25/2008 Physician France
Primary
Concomitant
Suicidal Ideation Other Serious 4/18/2008 46 Female 7/1/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Overdose Other Serious 1/1/2006 Female 6/30/2008 Consumer United States
Primary
Concomitant
Neutropenia Other Serious 6/17/2008 Female 7/1/2008 Pharmacist United States
Primary
Concomitant
Hepatic Failure Other Serious 4/1/2008 Male 137 lb 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Interacting
Vomiting Hospitalization 6/19/2008 59 Male 7/3/2008 Physician France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 217 lb 7/18/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 192 lb 7/25/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Depression Hospitalization 1/1/2006 50 Female 8/18/2008 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 1/1/2006 74 Male 8/18/2008 Physician United States
Primary
Secondary
Pulmonary Oedema Death 1/1/2006 46 Female 8/18/2008 Physician United States
Primary
Secondary
Concomitant
Neck Pain Other Serious 7/10/2008 Male 214 lb 8/26/2008 Physician United States
Primary
Concomitant
Urine Abnormality Other Serious 10/4/2007 Female 90 lb 9/2/2008 Consumer United States
Primary
Concomitant
Pulmonary Thrombosis Other Serious 7/10/2008 Male 214 lb 9/8/2008 Physician United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 Female 134 lb 9/19/2008 Physician United States
Primary
Concomitant
Paralysis Disability 9/13/2008 Female 9/22/2008 Pharmacist
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/1/2005 35 Female 9/19/2008 Physician United States
Primary
Secondary
Weight Decreased Hospitalization 10/1/2004 Female 260 lb 9/25/2008 Consumer United States
Primary
Concomitant
Urine Abnormality Other Serious 10/4/2007 Female 90 lb 9/25/2008 Consumer United States
Primary
Concomitant
T-cell Lymphoma Other Serious 5/1/2008 Female 10/20/2008 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 5/4/2007 Female 11/24/2008 Physician United States
Primary
Concomitant

Drug Data