Clonazepam combined with Methadone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 3/28/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/12/2006 50 Female 200 lb 4/7/2006 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2007 37 Male 12/24/2008 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2007 32 Male 12/23/2008 Physician United States
Primary
Secondary
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2005 42 Female 257 lb 4/3/2009 United States
Primary
Concomitant
Tearfulness Other Serious 8/11/2004 60 Female 160 lb 4/3/2009 United States
Primary
Concomitant
Unevaluable Event Male 5/4/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 5/18/2009 Physician United States
Primary
Secondary
Concomitant
Anxiety Hospitalization 5/11/2009 62 Male 162 lb 5/20/2009 Physician United States
Primary
Concomitant
Pulmonary Oedema Death 5/22/2009 Other Health Professional United States
Primary
Secondary
Dizziness Hospitalization 5/11/2009 62 Male 162 lb 5/26/2009 Physician United States
Primary
Concomitant
Pulmonary Oedema Death Male 5/29/2009 Other Health Professional United States
Primary
Secondary
Myalgia Other Serious 2/12/2009 Male 161 lb 7/7/2009 Physician France
Primary
Secondary
Concomitant
Pruritus Generalised 6/9/2009 52 Female 154 lb 7/8/2009 Other Health Professional United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death 8/15/2008 Female 287 lb 7/13/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 12/1/2005 53 Female 200 lb 8/6/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2006 48 Female 201 lb 8/25/2009 United States
Primary
Concomitant
Pulmonary Congestion Hospitalization 7/10/2007 45 Female 8/28/2009 United States
Primary
Concomitant
Erectile Dysfunction 8/1/2009 Male 8/31/2009 Consumer
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/22/2008 57 Male 10/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 Female 157 lb 10/29/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 11/17/2009 Physician United States
Primary
Secondary
Concomitant
Tremor 1/1/2009 22 Male 12/9/2009 Consumer United States
Primary
Secondary
Concomitant
Fracture Other Serious Female 120 lb 12/18/2009 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 5/17/2009 65 Female 12/29/2009 Consumer United States
Primary
Secondary
Concomitant
Pain Disability 1/1/2006 Female 1/8/2010 Consumer United States
Primary
Concomitant
Death Death 1/1/2008 30 Female 1/14/2010 Physician United States
Primary
Secondary
Sedation Other Serious 32 Female 1/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Poisoning Death 1/1/2008 30 Female 2/2/2010 Physician United States
Primary
Secondary
Depression Suicidal Hospitalization 2/17/2010 42 Female 2/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 2/25/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 6/1/2009 Female 3/2/2010 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/27/2010 43 Male 192 lb 3/10/2010 Pharmacist United States
Primary
Concomitant
Death Death 1/1/2008 30 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2008 22 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2008 45 Male 3/24/2010 Other Health Professional United States
Primary
Secondary
Therapeutic Agent Toxicity Death 11/12/2009 Male 141 lb 3/26/2010 Consumer
Primary
Secondary
Hypersomnia Other Serious 5/21/2008 41 Female 220 lb 4/26/2010 Physician Finland
Primary
Concomitant
Gait Disturbance Other Serious 1/1/2008 59 Female 110 lb 5/5/2010 Other Health Professional Sweden
Primary
Concomitant
Interacting
Vasculitis Hospitalization 9/1/2009 59 Male 161 lb 5/20/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2003 47 Male 298 lb 5/27/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 58 Male 310 lb 5/31/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/25/2002 43 Male 257 lb 6/1/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 48 Female 170 lb 7/2/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 7/7/2010 United States
Primary
Secondary
Concomitant
Incorrect Route Of Drug Administration Hospitalization 2/1/2010 53 Male 204 lb 7/8/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 8/24/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 8/25/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious Female 188 lb 8/26/2010 Physician United States
Primary
Secondary
Concomitant
Foot Fracture Hospitalization 1/1/2008 53 Female 150 lb 8/27/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious Female 188 lb 8/30/2010 Physician United States
Primary
Secondary
Concomitant
Memory Impairment Other Serious 8/27/2010 49 Female 160 lb 9/8/2010 Consumer United States
Primary
Concomitant
Swelling Other Serious 7/16/2010 44 Female 215 lb 9/9/2010 Physician United States
Primary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 9/10/2010 Physician Sweden
Primary
Concomitant
Interacting
Vertigo Other Serious 1/1/2000 59 Female 110 lb 9/15/2010 Other Health Professional Sweden
Primary
Concomitant
Interacting
White Blood Cell Count Increased Other Serious Female 188 lb 9/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nightmare Female 243 lb 9/15/2010 Consumer United States
Primary
Concomitant
Memory Impairment Other Serious 8/27/2010 49 Female 160 lb 9/16/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 64 Female 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Hypersomnia Other Serious 5/21/2008 41 Female 220 lb 9/16/2010 Physician Finland
Primary
Concomitant
Pancreatitis Other Serious 1/1/2005 67 Female 175 lb 9/17/2010 United States
Primary
Concomitant
Sedation 32 Female 9/17/2010 Pharmacist United States
Primary
Concomitant
Interacting
Lung Infiltration Other Serious 1/1/2000 59 Female 110 lb 9/23/2010
Primary
Secondary
Memory Impairment Other Serious 8/27/2010 49 Female 159 lb 9/23/2010 Consumer United States
Primary
Concomitant
Myalgia Other Serious 9/11/2010 Male 9/24/2010 Physician United States
Primary
Concomitant
Vertigo Other Serious 59 Female 110 lb 9/29/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Memory Impairment Other Serious 8/27/2010 49 Female 159 lb 10/1/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 10/7/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 10/7/2010 United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Other Serious 3/1/2008 28 Female 168 lb 10/7/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/11/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2002 50 Female 188 lb 10/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 10/13/2010 Physician Sweden
Primary
Concomitant
Interacting
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/13/2010 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 59 Female 110 lb 10/15/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2002 50 Female 188 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/25/2010 United States
Primary
Secondary
Concomitant
Sudden Death Death 1/1/2006 31 Male 11/3/2010 Other Health Professional France
Primary
Secondary
Sudden Death Death 1/1/2005 28 Male 11/3/2010 Other Health Professional France
Primary
Secondary
Unresponsive To Stimuli Hospitalization 30 Female 11/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2002 50 Female 188 lb 12/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrosclerosis Required Intervention 4/18/2008 59 Female 125 lb 11/23/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 12/13/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 64 Female 2/25/2010 Physician United States
Primary
Secondary
Concomitant
Hypersomnia Other Serious 5/21/2008 41 Female 220 lb 4/26/2010 Physician Finland
Primary
Concomitant
Grand Mal Convulsion Other Serious 11/30/2010 47 Male 198 lb 12/16/2010 Physician Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 12/20/2010 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 30 Female 12/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 58 Male 12/21/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2002 50 Female 188 lb 12/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 12/30/2010 United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 70 Female 1/4/2011 Other Health Professional United States
Primary
Secondary
Agitation Other Serious Male 1/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 70 Female 1/11/2011 Other Health Professional United States
Primary
Secondary
Coordination Abnormal Hospitalization 8/17/2010 71 Female 220 lb 9/8/2010 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 70 Female 1/13/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 45 Female 1/19/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 35 Male 1/19/2011 Physician United States
Primary
Secondary
Death Death 17 Male 1/19/2011 Physician United States
Primary
Secondary
Completed Suicide Death 19 Male 1/19/2011 Physician United States
Primary
Secondary
Completed Suicide Death 70 Female 1/19/2011 Physician United States
Primary
Secondary
Hyperlipidaemia Hospitalization 1/1/2002 38 Female 170 lb 1/20/2011 Consumer United States
Primary
Concomitant
Malaise Other Serious 1/1/2011 50 Female 183 lb 1/20/2011 Consumer United States
Primary
Concomitant
Interacting
Toxicity To Various Agents Death 1/1/2009 70 Female 1/19/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 1/1/2009 70 Female 1/27/2011 Physician United States
Primary
Secondary
Poisoning Death 1/1/2009 70 Female 1/27/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 19 Male 2/8/2011 Physician United States
Primary
Secondary
Osteoarthritis Other Serious 1/1/2005 63 Male 177 lb 2/28/2011 United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 19 Male 3/1/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 70 Female 3/8/2011 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 70 Female 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2005 63 Male 177 lb 3/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 35 Male 3/24/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 45 Female 3/24/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 17 Male 3/24/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 19 Male 3/24/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 70 Female 3/24/2011 Physician United States
Primary
Secondary
Pain Male 220 lb 3/25/2011 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious Male 3/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Emotional Distress Other Serious 2/27/2009 69 Male 3/30/2011 Physician United States
Primary
Concomitant
Product Quality Issue Life Threatening 1/27/2011 36 Male 4/11/2011 Pharmacist Australia
Primary
Concomitant
Muscle Spasms Other Serious 1/28/2011 49 Female 193 lb 3/31/2011 Consumer United States
Primary
Concomitant
Drug Tolerance Other Serious 4/14/2011 Other Health Professional United States
Primary
Secondary
Liver Function Test Abnormal Life Threatening 1/27/2011 36 Male 4/27/2011 Other Health Professional Australia
Primary
Concomitant
Renal Failure Acute Death 4/4/2011 56 Male 249 lb 5/3/2011 Physician United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 11/30/2010 47 Male 198 lb 5/4/2011 Physician Canada
Primary
Concomitant
Calcification Metastatic Other Serious 1/1/2002 50 Female 188 lb 5/4/2011 Physician United States
Primary
Secondary
Concomitant
Hallucination Other Serious 8/1/2009 46 Female 7/14/2011 Lawyer United States
Primary
Concomitant
Weight Increased 7/1/2011 60 Female 140 lb 9/7/2011 Consumer United States
Primary
Concomitant
Screaming Other Serious 1/1/2007 46 Female 96 lb 9/28/2011 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 1/1/2010 46 Female 12/22/2011 Physician United States
Primary
Secondary
Cyst Other Serious Male 212 lb 1/4/2012 Consumer United States
Primary
Secondary
Concomitant
Blood Prolactin Abnormal Hospitalization 58 Male 1/25/2012 Other Health Professional United States
Primary
Concomitant
Jaundice Neonatal Congenital Anomaly 9/10/2009 Female 7 lb 2/21/2012 Lawyer United States
Primary
Concomitant
Headache 1/1/2011 53 Male 251 lb 4/2/2012 Consumer United States
Primary
Concomitant
Suicide Attempt Hospitalization 1/1/2012 33 Male 176 lb 7/8/2012 Consumer Spain
Primary
Concomitant
Drug Abuse Hospitalization 1/1/2012 33 Male 176 lb 7/10/2012 Consumer Spain
Primary
Concomitant
Drug Abuse Other Serious 1/1/2012 33 Male 176 lb 7/20/2012 Consumer Spain
Primary
Concomitant
Alveolar Osteitis 5/18/2012 41 Male 7/30/2012 Consumer United States
Primary
Concomitant
Constipation Other Serious 1/1/2008 46 Female 8/15/2012 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 57 Male 8/21/2012 Physician United States
Primary
Concomitant
Vomiting Other Serious 42 Male 180 lb 11/7/2012 Consumer Us
Primary
Concomitant
Renal Injury Other Serious 53 Female 187 lb 11/21/2012 Other Health Professional Us
Primary
Concomitant
Weight Decreased Hospitalization 58 Male 12/27/2012 Other Health Professional Us
Primary
Concomitant
Tardive Dyskinesia Other Serious Female 200 lb 10/19/2012 Lawyer Us
Primary
Concomitant
Oesophagitis Other Serious Female 192 lb 10/31/2012 Lawyer Us
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 8/2011 Female 140 lb 12/13/2012 Physician Ca
Primary
Concomitant
Weight Increased Other Serious 2007 51 Female 130 lb 12/28/2012 Consumer Us
Primary
Concomitant

Drug Data