Clonazepam combined with Metformin

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Overdose Hospitalization 1/1/2004 53 Female 220 lb 1/19/2006 Lawyer United States
Primary
Concomitant
Somnolence Other Serious 1/18/2006 Female 245 lb 1/30/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 40 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Vomiting 49 Female 2/27/2006 Consumer United States
Primary
Concomitant
Mental Disorder Hospitalization 10/1/2005 Female 3/10/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2004 53 Female 220 lb 3/24/2006 Physician United States
Primary
Concomitant
Nightmare Other Serious 12/19/2005 Male 258 lb 3/15/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 3/28/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 4/3/2006 48 Female 4/11/2006 Pharmacist United States
Primary
Concomitant
Viral Infection Hospitalization 1/1/2005 Female 155 lb 4/18/2006 Consumer United States
Primary
Concomitant
Victim Of Crime Other Serious 1/1/2004 53 Female 220 lb 4/24/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 7/19/2005 61 Female 151 lb 2/8/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vaginal Infection Hospitalization 1/1/2004 46 Female 260 lb 4/21/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/21/2006 63 Female 220 lb 5/12/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms 2/14/2006 84 Female 205 lb 4/3/2006 Consumer United States
Primary
Concomitant
Pregnancy Hospitalization 3/22/2006 30 Female 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2005 37 Male 6/7/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Pain Hospitalization 7/1/2004 61 Female 220 lb 6/19/2006 Consumer United States
Primary
Concomitant
Somnolence Other Serious 1/18/2006 Female 245 lb 6/27/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 8/19/2005 58 Male 205 lb 4/17/2006 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Death 4/19/2006 Female 325 lb 7/7/2006 Physician Canada
Primary
Concomitant
Oedema Peripheral Female 7/21/2006 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/19/2006 63 Male Pharmacist United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/30/2005 64 Male 177 lb 2/8/2006 Consumer United States
Primary
Concomitant
Wolff-parkinson-white Syndrome Other Serious 1/1/2006 58 Female 220 lb 7/27/2006 United States
Primary
Secondary
Concomitant
Wolff-parkinson-white Syndrome Other Serious 1/1/2006 58 Female 220 lb 9/8/2006 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 2/8/2006 59 Male 225 lb 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Throat Irritation 6/1/2006 52 Female 235 lb 8/20/2006 United States
Primary
Concomitant
Muscle Spasms Other Serious 10/7/2006 41 Male 222 lb 11/2/2006 United States
Primary
Concomitant
Weight Increased Hospitalization 9/21/2006 78 Male 212 lb 11/2/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 12/5/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/25/2006 Female 185 lb 11/8/2006 Pharmacist United States
Primary
Secondary
Concomitant
Cataract Other Serious 1/1/2006 Male 205 lb 1/25/2007 Physician United States
Primary
Concomitant
Pollakiuria Other Serious 1/1/2004 72 Female 134 lb 6/14/2005 United States
Primary
Concomitant
Erythema Multiforme Other Serious 5/1/2007 62 Female 205 lb 8/13/2007 Physician United States
Primary
Concomitant
Erythema Multiforme Other Serious 5/1/2007 62 Female 205 lb 8/22/2007 Other Health Professional United States
Primary
Concomitant
Skin Laceration Hospitalization 12/1/2006 Female 10/17/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 10/25/2007 Consumer United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 2/19/2007 55 Male 236 lb 10/26/2007 Physician Canada
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 2/14/2007 Male 225 lb 11/6/2007 Pharmacist United States
Primary
Concomitant
Incorrect Dose Administered Other Serious 12/28/2007 40 Female 143 lb 1/21/2008 Consumer Brazil
Primary
Concomitant
Arthralgia 9/28/2007 40 Female 2/15/2008 United States
Primary
Concomitant
Smear Cervix Abnormal 3/10/2007 Female 178 lb 3/15/2008 Physician United States
Primary
Concomitant
Rectal Haemorrhage 12/1/2007 Female 170 lb 3/15/2008 Consumer United States
Primary
Concomitant
Respiratory Tract Congestion 1/1/2007 Female 170 lb 3/15/2008 United States
Primary
Concomitant
Suicide Attempt Hospitalization 5/7/2008 Female 6/13/2008 Consumer Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 194 lb 6/17/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 38 Male 198 lb 6/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Multiple Drug Overdose Death 71 6/19/2008 Physician United States
Primary
Secondary
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 6/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/20/2008 Consumer Brazil
Primary
Secondary
Concomitant
Parkinson's Disease Hospitalization 5/1/2008 67 Male 223 lb 6/23/2008 Physician France
Primary
Concomitant
Renal Failure Acute Other Serious 5/1/2008 70 Male 7/7/2008 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/1/2008 70 Male 8/20/2008 Physician France
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2002 63 Female 191 lb 8/25/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 5/1/2008 70 Male 9/9/2008 Physician France
Primary
Secondary
Concomitant
Pancreatitis Other Serious Female 9/9/2008 Consumer United States
Primary
Concomitant
Colon Cancer Hospitalization 2/15/2008 53 Male 212 lb 10/10/2008 Physician Canada
Primary
Concomitant
Vision Blurred Other Serious 11/1/2008 53 Male 172 lb 12/31/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 5/1/2006 58 Female 190 lb 1/13/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/20/2008 79 Female 150 lb 1/12/2009 Other Health Professional United States
Primary
Concomitant
Occult Blood Positive Hospitalization 9/9/2008 64 Female 284 lb 1/13/2009 Pharmacist United States
Primary
Concomitant
Urinary Retention Hospitalization 60 Male 218 lb 1/23/2009 Physician Canada
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 1/23/2009 Other Health Professional France
Primary
Concomitant
Urinary Retention Hospitalization 60 Male 218 lb 1/29/2009 Physician Canada
Primary
Concomitant
Renal Failure Acute Other Serious 5/1/2008 70 Male 2/20/2009 Physician France
Primary
Secondary
Concomitant
Spinal Disorder Hospitalization 12/1/2007 87 Male 2/26/2009 Consumer Mexico
Primary
Concomitant
Skin Lesion Other Serious Female 155 lb 3/5/2009 Canada
Primary
Concomitant
Malaise Other Serious 2/1/2009 Female 290 lb 3/9/2009 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/11/2009 62 Male 179 lb 3/18/2009 Pharmacist United States
Primary
Concomitant
Psychotic Disorder Hospitalization 6/11/2004 53 Male 204 lb 4/1/2009 United States
Primary
Secondary
Concomitant
Lip Discolouration Other Serious 2/1/2009 Female 290 lb 5/8/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/1/2009 Female 187 lb 6/19/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 4/1/2009 Female 187 lb 6/26/2009 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/11/2009 Female 141 lb 7/1/2009 Canada
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/14/2009 49 Male 7/21/2009 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/29/2009 Female 234 lb 6/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious 2/21/2007 78 Female 200 lb 7/29/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/1/2009 Female 187 lb 7/28/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 4/1/2009 Female 187 lb 7/27/2009 Physician United States
Primary
Concomitant
Surgery Hospitalization 5/7/2009 Male 247 lb 7/10/2009 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 6/20/2000 42 Male 285 lb 8/13/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 56 Female 8/13/2009 Consumer United States
Primary
Secondary
Concomitant
Gastric Ulcer Other Serious 1/1/2009 50 Female 317 lb 8/17/2009 Consumer United States
Primary
Concomitant
Flushing Male 8/21/2009 United States
Primary
Concomitant
Blood Glucose Increased Male 8/22/2009 United States
Primary
Concomitant
Flushing 9/5/2008 Female 8/22/2009 United States
Primary
Concomitant
Spinal Disorder Hospitalization 12/1/2007 87 Male 9/1/2009 Consumer Mexico
Primary
Concomitant
Nocturia Other Serious 8/19/2009 56 9/9/2009 Consumer Brazil
Primary
Concomitant
Rheumatoid Lung Other Serious 9/24/2009 Female 187 lb 10/1/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/20/2004 46 Male 234 lb 10/5/2009 United States
Primary
Concomitant
Organising Pneumonia Life Threatening Female 10/7/2009 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 8/1/2009 Male 200 lb 10/8/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/1/2002 56 10/9/2009 Consumer Brazil
Primary
Secondary
Concomitant
Acquired Macroglossia Other Serious 9/11/2009 Female 188 lb 10/14/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2008 52 Female 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/13/2008 52 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/14/2009 49 Male 10/29/2009 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/1/2002 56 Male 216 lb 11/3/2009 Physician Brazil
Primary
Secondary
Concomitant
Psoriasis Other Serious 6/11/2009 Female 162 lb 11/6/2009 Consumer Canada
Primary
Concomitant
Psoriasis Other Serious 6/11/2009 Female 162 lb 11/9/2009 Consumer Canada
Primary
Concomitant
Vomiting Life Threatening 8/1/2009 57 Male 141 lb 11/16/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/1/2009 57 Male 141 lb 11/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Flushing 10/1/2009 Female 225 lb 11/25/2009 United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2006 36 Female 263 lb 11/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Other Serious 11/18/2009 Female 140 lb 12/14/2009 Canada
Primary
Concomitant
Paraesthesia Other Serious 11/18/2009 Female 140 lb 12/29/2009 Canada
Primary
Concomitant
Completed Suicide Death 66 Female 12/30/2009 Physician United States
Primary
Secondary
Mania Hospitalization 10/17/2009 Female 135 lb 10/19/2009 United States
Primary
Concomitant
Pain Disability 1/1/2006 Female 1/8/2010 Consumer United States
Primary
Concomitant
Drug Toxicity Death 60 Female 1/13/2010 Physician United States
Primary
Secondary
Visual Impairment Other Serious 75 Male 165 lb 1/14/2010 United States
Primary
Concomitant
Completed Suicide Death 1/1/2008 75 Female 1/15/2010 Physician United States
Primary
Secondary
Drug Toxicity Death 60 Female 1/19/2010 Physician United States
Primary
Secondary
Overdose Death 75 Female 1/20/2010 Physician United States
Primary
Secondary
Drug Toxicity Other Serious 60 Female 1/20/2010 Physician United States
Primary
Secondary
Intestinal Adenocarcinoma Other Serious 11/26/2009 59 Female 178 lb 1/21/2010 Physician Canada
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2000 57 Female 186 lb 1/25/2010 United States
Primary
Concomitant
Intestinal Adenocarcinoma Other Serious 11/26/2009 59 Female 178 lb 1/25/2010 Physician Canada
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 46 Female 1/25/2010 Consumer Canada
Primary
Concomitant
Withdrawal Syndrome Other Serious 12/1/2009 Female 240 lb 2/8/2010 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 60 Female 2/22/2010 United States
Primary
Secondary
Completed Suicide Death 75 Female 2/22/2010 United States
Primary
Secondary
Coronary Artery Bypass Hospitalization Female 127 lb 2/22/2010 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 8/1/2009 57 Male 141 lb 3/5/2010 Other Health Professional France
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 1/27/2010 46 Female 230 lb 3/15/2010 Consumer Canada
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization Female 163 lb 4/5/2010 Other Health Professional United States
Primary
Concomitant
Palpitations Other Serious 3/29/2010 62 Female 4/7/2010 Consumer Brazil
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/1/2009 58 Female 176 lb 4/8/2010 Consumer Brazil
Primary
Concomitant
Weight Increased Other Serious 5/1/2002 54 Male 216 lb 4/13/2010 Physician Brazil
Primary
Secondary
Concomitant
Vascular Insufficiency Hospitalization 6/24/2006 71 Male 168 lb 4/21/2010 Physician Poland
Primary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 4/3/2010 55 Female 4/23/2010 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Life Threatening 3/22/2010 61 Female 4/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hyperkalaemia Life Threatening 3/22/2010 61 Female 4/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 3/22/2010 4/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death Female 163 lb 4/29/2010 Consumer United States
Primary
Concomitant
Hyperkalaemia Life Threatening 3/22/2010 61 Female 5/5/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 29 Female 274 lb 6/3/2010 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 6/1/2007 60 Female 163 lb 6/16/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 1/1/2009 52 Female 187 lb 6/22/2010 Physician Canada
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 7/13/2010 United States
Primary
Secondary
Concomitant
Middle Insomnia 3/15/2008 63 Female 168 lb 7/21/2010 Consumer United States
Primary
Concomitant
Wound Other Serious 4/28/2008 49 Female 220 lb 7/21/2010 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 5/12/2008 63 Female 154 lb 7/22/2010 Consumer United States
Primary
Concomitant