Clonazepam combined with Lorazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Required Intervention 4/1/2002 39 Male 213 lb 12/30/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2005 68 Female 220 lb 1/17/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 68 Female 1/18/2006 Physician United States
Primary
Concomitant
Hemiparesis Hospitalization 3/13/2004 61 Female 128 lb 1/18/2006 Physician United States
Primary
Concomitant
Skin Discolouration Other Serious 1/4/2006 Female 110 lb 2/3/2006 Canada
Primary
Concomitant
Urine Output Decreased Hospitalization 81 Male 2/7/2006 Pharmacist United States
Primary
Secondary
Transient Ischaemic Attack Other Serious 1/1/2000 72 Female 150 lb 2/17/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/21/2001 52 Female 141 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 11/16/2005 55 Male 161 lb 12/13/2005 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Disability 4/1/2005 19 Male 175 lb 2/24/2006 Consumer United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 1/4/2006 Female 110 lb 2/27/2006 Physician Canada
Primary
Concomitant
Skin Discolouration Other Serious 1/4/2006 Female 110 lb 2/27/2006 Consumer Canada
Primary
Concomitant
Skin Discolouration Other Serious 1/4/2006 Female 110 lb 2/27/2006 Consumer Canada
Primary
Concomitant
Drug Ineffective Other Serious 2/14/2006 47 Male 150 lb 2/22/2006 United States
Primary
Concomitant
Pharyngolaryngeal Pain Disability 1/1/1999 46 Male 201 lb 3/1/2006 Physician United States
Primary
Concomitant
Dementia Alzheimer's Type Death 1/10/2006 83 Female 2/27/2006 United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/1/1999 46 Male 201 lb 3/10/2006 Physician United States
Primary
Concomitant
Drug Tolerance Increased Other Serious Female 162 lb 3/14/2006 Other Health Professional United States
Primary
Concomitant
Mental Disorder Hospitalization 10/1/2005 Female 3/10/2006 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 3/10/2006 United States
Primary
Concomitant
Vomiting Other Serious 12/2/2001 44 Female 201 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 44 Female 201 lb 3/23/2006 Physician United States
Primary
Concomitant
Vertigo Other Serious 1/1/2000 72 Female 150 lb 3/24/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 3/24/2006 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 8/22/2005 Female 4/14/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Disease Progression Death 1/10/2006 83 Female 4/17/2006 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 10/25/1999 42 Female 4/17/2006 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 8/29/2001 58 Female 130 lb 5/8/2006 Lawyer United States
Primary
Concomitant
Poor Quality Drug Administered Other Serious 1/2/2006 46 Female 140 lb 5/5/2006 Consumer United States
Primary
Secondary
Tremor Life Threatening 3/9/2006 40 Male 205 lb 3/10/2006 United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2000 59 Male 220 lb 5/17/2006 Lawyer United States
Primary
Concomitant
Suicidal Ideation Other Serious 10/25/1999 42 Female 238 lb 5/22/2006 Consumer United States
Primary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2000 Female 126 lb 6/8/2006 Physician United States
Primary
Concomitant
Vomiting 7/27/2005 52 Male 7/12/2006 Consumer United States
Primary
Concomitant
Weight Loss Poor 2/1/2004 68 Female 197 lb 7/21/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/14/2005 29 Male 150 lb 3/22/2006 United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/25/1999 42 Female 238 lb 7/26/2006 Consumer United States
Primary
Concomitant
Anaemia 9/2/2005 Female 213 lb 8/9/2006 Physician United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 5/10/2006 52 Female 155 lb 8/18/2006 Physician United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/10/2006 52 Female 5/22/2006 United States
Primary
Concomitant
Nausea 5/10/2006 42 Male 8/28/2006 Consumer United States
Primary
Concomitant
Stem Cell Transplant Other Serious 1/26/2005 41 Female 132 lb 8/17/2006 Physician Canada
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/25/1999 42 Female 238 lb 8/22/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Required Intervention 8/24/2006 57 Male 290 lb 8/24/2006 Pharmacist United States
Primary
Concomitant
Vertigo Hospitalization 5/23/2006 71 Female 8/22/2006 Other Health Professional France
Primary
Concomitant
Vomiting Hospitalization 41 Male 9/15/2006 Physician United States
Primary
Concomitant
Drug Level Increased Hospitalization 43 Male 9/15/2006 Consumer United States
Primary
Concomitant
Therapy Regimen Changed Other Serious 10/25/1999 42 Female 238 lb 9/11/2006 Consumer United States
Primary
Concomitant
Haemorrhage Other Serious 9/8/2006 42 Female 9/21/2006 Pharmacist Canada
Primary
Concomitant
Weight Increased Hospitalization 1/1/2000 Female 126 lb 10/6/2006 Physician United States
Primary
Concomitant
Throat Tightness Other Serious 10/3/2006 41 Female 10/18/2006 Other Health Professional Canada
Primary
Concomitant
Weight Increased Hospitalization 1/1/2000 Female 126 lb 10/24/2006 Physician United States
Primary
Concomitant
Tremor Death 7/19/2002 17 Male 10/25/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2000 Female 126 lb 10/26/2006 Physician United States
Primary
Concomitant
Nausea Hospitalization 9/25/2006 Female 135 lb 10/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Life Threatening 9/9/2006 60 Male 164 lb 10/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thermal Burn Other Serious 11/3/2002 47 Male 11/3/2006 Lawyer United States
Primary
Secondary
Concomitant
Poisoning Death 68 NotSpecified 11/16/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 42 NotSpecified 11/16/2006 Physician United States
Primary
Secondary
Hepatocellular Damage 9/22/2006 62 Female 11/15/2006 Switzerland
Primary
Concomitant
Respiratory Arrest Death 42 11/17/2006 Physician United States
Primary
Secondary
Poisoning Death 68 11/17/2006 Physician United States
Primary
Secondary
Drug Toxicity Death 1/1/2005 68 11/21/2006 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2005 68 11/21/2006 Physician United States
Primary
Secondary
Visual Disturbance Other Serious 1/1/2002 47 Male 230 lb 11/30/2006 Physician United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 1/1/1986 Male 212 lb 12/1/2006 Consumer Canada
Primary
Concomitant
Respiratory Failure Other Serious 1/26/2005 41 Female 132 lb 12/4/2006 Other Health Professional Canada
Primary
Concomitant
Therapy Regimen Changed Life Threatening 9/1/2006 60 Male 164 lb 12/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Wrong Drug Administered 11/3/2006 Pharmacist United States
Primary
Secondary
Suicide Attempt Other Serious Male 12/22/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/10/2006 50 Female 134 lb 1/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 11/25/2006 42 Female 137 lb 1/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/5/2006 38 Male 226 lb 1/18/2007 Physician United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 7/1/2006 81 Female 11/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/17/2004 45 Female 230 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Death Death 1/1/2005 68 Unknown 2/12/2007 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2005 42 Unknown 2/12/2007 Physician United States
Primary
Secondary
Pain Other Serious 66 Male 201 lb 2/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Retroperitoneal Haematoma Other Serious 66 Male 201 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Other Serious 66 Male 201 lb 2/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Hospitalization 66 Male 2/20/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 2/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 4/28/2004 52 Female 2/27/2007 Lawyer United States
Primary
Secondary
International Normalised Ratio Increased Hospitalization 1/1/2006 66 Male 201 lb 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 66 Male 201 lb 2/23/2007 United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 66 Male 201 lb 2/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 47 Female 3/23/2007 Lawyer United States
Primary
Concomitant
Suicide Attempt Other Serious 4/28/2004 Female 3/23/2007 Lawyer United States
Primary
Secondary
Photopsia Other Serious 3/1/2007 Female 165 lb 3/30/2007 Consumer United States
Primary
Concomitant
Renal Impairment Life Threatening 10/13/2006 Female 121 lb 4/3/2007 Netherlands
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2002 Female 202 lb 4/4/2007 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/18/2007 70 Female 4/4/2007 Consumer United States
Primary
Concomitant
Death Death 39 Female 4/6/2007
Primary
Secondary
Extrapyramidal Disorder Other Serious Female 4/12/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Sleep Walking Other Serious 1/4/2003 Female 4/13/2007 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/29/2006 42 Female 4/6/2007 Other Health Professional United States
Primary
Concomitant
Death Death 39 Female 4/18/2007
Primary
Secondary
Somnolence Other Serious 4/9/2007 Female 4/19/2007 Consumer Canada
Primary
Concomitant
Oedema Peripheral Life Threatening 9/1/2006 60 Male 164 lb 4/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2000 Female 126 lb 4/24/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 4/25/2007 Consumer Canada
Primary
Concomitant
Grand Mal Convulsion Hospitalization 11/29/2006 60 Female 190 lb 4/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 1/15/2007 44 Male 4/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Arrhythmia Other Serious Male 4/30/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Extrapyramidal Disorder Other Serious 4/17/2001 Female 4/30/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/1/2007 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 4/28/2004 Female 5/8/2007 Lawyer United States
Primary
Secondary
Sinusitis Hospitalization 1/2/2007 60 Male 4/27/2007 Other Health Professional Switzerland
Primary
Concomitant
Dyspnoea Hospitalization 1/18/2007 70 Female 5/16/2007 Consumer United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Stage Iv Other Serious 3/21/2007 55 Female 5/11/2007 Consumer United States
Primary
Concomitant
Sputum Culture Positive Hospitalization 1/2/2007 61 Male 5/9/2007 Other Health Professional Switzerland
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 5/18/2007 Consumer Canada
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 12/1/2001 49 Male 161 lb 5/18/2007 Consumer United States
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 140 lb 5/24/2007 Consumer Canada
Primary
Concomitant
Toxic Induced Encephalopathy Other Serious 4/15/2007 78 Male 128 lb 5/18/2007 Physician Switzerland
Primary
Concomitant
Subcutaneous Abscess Other Serious 2/5/2007 39 Female 178 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1999 47 210 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Drug Level Decreased Hospitalization 1/1/2007 Female 6/19/2007 Pharmacist Canada
Primary
Concomitant
Weight Increased Other Serious 1/1/1983 Female 194 lb 6/20/2007 Consumer United States
Primary
Concomitant
Poisoning Death 39 Female 6/21/2007 Germany
Primary
Secondary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 6/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 25 Male 6/27/2007 Physician Italy
Primary
Concomitant
Drug Level Decreased Hospitalization 1/1/2007 Female 6/29/2007 Pharmacist Canada
Primary
Concomitant
Pain Hospitalization 66 Male 201 lb 7/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2000 Female 126 lb 7/2/2007 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 63 Female 7/11/2007
Primary
Secondary
Retroperitoneal Haematoma Other Serious 66 Male 7/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 66 Male 201 lb 7/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Overdose 6/28/2007 55 Female 7/16/2007 Physician Netherlands
Primary
Concomitant
Traumatic Haematoma Other Serious 27 Female 7/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Loss Poor 2/1/2004 68 Female 197 lb 7/23/2007 Consumer United States
Primary
Concomitant
Hyperthyroidism Hospitalization 21 Male 8/1/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Hepatic Steatosis Other Serious 4/1/2007 41 Female 8/2/2007 Physician United States
Primary
Concomitant
Stress Other Serious 10/9/2000 Female 132 lb 8/3/2007 Physician United States
Primary
Concomitant
Insomnia Hospitalization 6/18/2007 Female 190 lb 8/6/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/1/2007 Female 143 lb 8/10/2007 Other Health Professional France
Primary
Concomitant
Interacting
Pain Hospitalization 66 Male 201 lb 8/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 8/17/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2006 66 Male 201 lb 8/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 66 Male 201 lb 8/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Retroperitoneal Haematoma Hospitalization 66 Male 8/16/2007 Pharmacist United Kingdom
Primary
Concomitant
Self Injurious Behaviour Other Serious 12/13/2006 17 Male 9/4/2007 Physician Japan
Primary
Concomitant

Drug Data