Clonazepam combined with Levothyroxine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Initial Insomnia 9/10/2005 63 Male 154 lb 1/5/2006 Consumer United States
Primary
Concomitant
Nausea Female 8/29/2008 United States
Primary
Concomitant
Completed Suicide Death 1/1/2007 37 Male 12/24/2008 Physician United States
Primary
Secondary
Drug Toxicity Death 57 Female 12/24/2008 Physician United States
Primary
Secondary
Peripheral Ischaemia Other Serious 11/29/2008 55 Female 158 lb 12/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Convulsion Other Serious 7/31/2008 Female 243 lb 12/29/2008 Physician Chile
Primary
Secondary
Concomitant
Completed Suicide Death 37 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Angina Unstable Other Serious 7/9/2001 Male 194 lb 1/8/2009 Physician United States
Primary
Concomitant
Angina Unstable Hospitalization 7/5/2001 Male 194 lb 1/9/2009 Physician United States
Primary
Concomitant
Occult Blood Positive Hospitalization 9/9/2008 64 Female 284 lb 1/13/2009 Pharmacist United States
Primary
Concomitant
Angina Unstable Hospitalization 7/5/2001 Male 194 lb 1/21/2009 Physician United States
Primary
Concomitant
Respiratory Arrest Other Serious 37 Male 1/23/2009 Physician United States
Primary
Secondary
Angina Unstable Other Serious 7/9/2001 Male 194 lb 1/24/2009 Physician United States
Primary
Concomitant
Death Death 1/1/2007 57 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Diffuse Large B-cell Lymphoma Stage Iv Other Serious 10/1/2008 Female 154 lb 2/6/2009 Consumer Chile
Primary
Concomitant
Neuropathy Peripheral Other Serious 2/26/2009 54 Female 128 lb 3/1/2009 Other Health Professional United States
Primary
Concomitant
Completed Suicide Death 37 Male 3/20/2009 Physician United States
Primary
Secondary
Urticaria Other Serious 10/29/2008 Female 3/25/2009 Physician United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 2/9/2008 Female 112 lb 3/24/2009 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/3/2009 Female 4/7/2009 Physician United States
Primary
Concomitant
Spinal Disorder Other Serious Female 197 lb 4/9/2009 Consumer United States
Primary
Concomitant
Interacting
Dysgeusia 12/15/2008 29 Male 4/24/2009 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 5/12/2009 57 5/20/2009 Brazil
Primary
Secondary
Concomitant
Spinal Disorder Other Serious Female 197 lb 5/21/2009 Physician United States
Primary
Concomitant
Interacting
Atrial Flutter Hospitalization 5/5/2009 57 5/22/2009 Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 50 Female 5/26/2009 Other Health Professional United States
Primary
Concomitant
Urine Leukocyte Esterase Positive Hospitalization 50 Female 5/27/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 5/12/2009 57 6/2/2009 Brazil
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 5/5/2009 57 6/4/2009 Physician Brazil
Primary
Secondary
Concomitant
Lethargy 7/4/2007 4 Male 43 lb 6/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Other Serious 6/8/2009 Other Health Professional United States
Primary
Secondary
Transient Ischaemic Attack Other Serious 2/3/2009 Female 5/28/2009 Physician United States
Primary
Concomitant
Shock Other Serious 6/24/2009 Other Health Professional United States
Primary
Secondary
Vomiting Other Serious 1/1/2005 38 Female 252 lb 6/25/2009 United States
Primary
Concomitant
Meningitis Aseptic Other Serious 50 Female 7/7/2009 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 1/1/2008 Female 230 lb 7/7/2009 Consumer United States
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 4/1/2009 Female 299 lb 7/15/2009 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 5/6/2009 Female 196 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/2/2007 64 Male 272 lb 8/7/2009 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization 6/11/2009 87 Female 159 lb 8/8/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/2/2007 64 Male 272 lb 8/12/2009 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 6/20/2000 42 Male 285 lb 8/13/2009 United States
Primary
Concomitant
Joint Dislocation Other Serious 7/20/2009 61 Female 8/7/2009 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 5/12/2009 57 8/14/2009 Brazil
Primary
Secondary
Concomitant
Facial Paresis Other Serious 1/1/2008 45 Female 8/16/2009 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 7/29/2009 79 Male 8/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 7/7/2009 Female 8/18/2009 Consumer United States
Primary
Concomitant
Nephrolithiasis Other Serious 6/25/2009 Female 235 lb 8/21/2009 United States
Primary
Concomitant
Headache 9/5/2008 Female 8/21/2009 United States
Primary
Concomitant
Rash 9/14/2008 Female 8/21/2009 Consumer United States
Primary
Concomitant
Skin Burning Sensation 8/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization Male 178 lb 9/4/2009 Physician United States
Primary
Concomitant
Pain Of Skin 1/1/2005 Female 9/8/2009 Consumer
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 4/1/2009 Female 299 lb 9/24/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 50 Female 9/21/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/19/2009 51 Female 223 lb 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 38 Female 260 lb 10/14/2009 United States
Primary
Concomitant
Vomiting Hospitalization 10/12/2008 Female 11/20/2009 Physician United States
Primary
Concomitant
Nausea Hospitalization 1/1/2009 Female 140 lb 1/19/2010 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 12/1/2009 Female 240 lb 2/8/2010 Consumer United States
Primary
Secondary
Concomitant
Rash 3/15/2009 46 Female 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 25 Female 2/26/2010 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral 7/29/2009 42 Male 162 lb 8/18/2009 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 11/13/2009 82 Female 12/8/2009 Pharmacist United States
Primary
Secondary
Concomitant
Uterine Leiomyoma Other Serious 9/1/1999 Female 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/8/2008 56 Female 159 lb 3/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Varices Oesophageal Hospitalization 12/1/2007 Male 3/10/2010 Consumer
Primary
Concomitant
Varices Oesophageal Hospitalization 12/1/2007 Male 3/13/2010 Consumer
Primary
Concomitant
Thrombocytopenia Hospitalization 9/19/2009 51 Female 223 lb 3/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Odour Abnormal Hospitalization 1/1/2010 58 Female 143 lb 4/5/2010 Consumer United States
Primary
Secondary
Concomitant
Femur Fracture Other Serious 9/18/2009 45 Female 4/14/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 66 Female 197 lb 4/16/2010 United States
Primary
Concomitant
Vomiting Other Serious 8/1/2009 72 Female 4/15/2010 Netherlands
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2009 52 Female 4/23/2010 Physician United States
Primary
Concomitant
Nausea Hospitalization 1/1/2009 49 Female 140 lb 4/26/2010 Consumer United States
Primary
Concomitant
Varices Oesophageal Hospitalization 12/1/2007 44 Male 4/30/2010 Physician
Primary
Concomitant
Vomiting Other Serious 8/1/2009 72 Female 4/27/2010 Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/1/2010 52 Male 212 lb 6/23/2010 Consumer United States
Primary
Secondary
Concomitant
Death Death 53 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 49 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 11/27/2009 58 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/6/2010 52 Male 212 lb 7/9/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 3/1/2010 57 Female 7/12/2010 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/1/2010 57 Female 168 lb 7/12/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 44 Female 192 lb 7/12/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting 3/1/2007 57 Female 135 lb 7/12/2010 Other Health Professional United States
Primary
Concomitant
Nausea 4/11/2007 49 Female 174 lb 7/12/2010 Consumer United States
Primary
Concomitant
Vomiting 5/1/2007 60 Female 112 lb 7/13/2010 Consumer United States
Primary
Concomitant
Surgery 9/28/2007 49 Female 180 lb 7/16/2010 Consumer United States
Primary
Concomitant
Tongue Discolouration Other Serious 6/27/2004 45 Female 7/27/2010 Consumer United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 6/1/2010 45 Male 7/23/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/22/2008 49 Female 8/3/2010 Other Health Professional United States
Primary
Concomitant
Swelling Face Other Serious 6/3/2008 49 Female 187 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 57 Female 180 lb 8/3/2010 Physician United States
Primary
Concomitant
Weight Increased Female 155 lb 8/3/2010 Consumer United States
Primary
Concomitant
Weight Increased Female 94 lb 8/4/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious Female 154 lb 8/4/2010 Consumer Brazil
Primary
Concomitant
Panic Attack 60 Female 8/9/2010 Consumer United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 4/13/2010 72 Female 185 lb 8/10/2010 Physician United States
Primary
Secondary
Concomitant
Tremor 1/1/2009 57 Female 229 lb 8/10/2010 Physician United States
Primary
Concomitant
Sinus Operation Female 8/13/2010 United States
Primary
Concomitant
Nausea Hospitalization 6/14/2010 77 Female 8/18/2010 Physician Canada
Primary
Concomitant
Vision Blurred Other Serious 1/1/2000 42 Male 265 lb 8/26/2010 United States
Primary
Concomitant
Pruritus Male 200 lb 8/29/2010 Consumer United States
Primary
Concomitant
Blood Glucose Increased 7/18/2010 91 Male 160 lb 8/29/2010 Consumer United States
Primary
Concomitant
Uterine Cancer Other Serious 11/1/2002 76 Female 8/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2004 39 Female 290 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Drug Ineffective Male 9/1/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 7/29/2010 65 Female 250 lb 9/2/2010 Consumer United States
Primary
Concomitant
Somnolence 3/23/2009 77 Female 139 lb 9/14/2010 Physician United States
Primary
Concomitant
Headache 6/15/2009 45 Female 152 lb 9/15/2010 Physician United States
Primary
Concomitant
Intentional Drug Misuse 5/1/2010 48 Female 207 lb 9/17/2010 United States
Primary
Concomitant
Intentional Drug Misuse 9/1/2009 75 Female 165 lb 9/17/2010 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 4/13/2010 72 Female 185 lb 9/20/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2003 30 Female 215 lb 9/20/2010 United States
Primary
Concomitant
Vomiting 7/1/2010 54 Female 150 lb 9/20/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious Female 10/5/2010 Consumer United States
Primary
Concomitant
Dyspnoea 81 Male 198 lb 10/13/2010 United States
Primary
Concomitant
Urticaria Other Serious 8/31/2010 57 Female 151 lb 10/7/2010 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 10/1/2009 52 Female 250 lb 10/22/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/8/2010 56 Female 315 lb 10/25/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased 8/1/2010 55 Female 158 lb 10/25/2010 United States
Primary
Concomitant
Drug Toxicity Death 57 Female 10/27/2010 Physician United States
Primary
Secondary
Vomiting Hospitalization 3/8/2008 56 Female 159 lb 10/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Female 180 lb 10/28/2010 Consumer United States
Primary
Concomitant
Product Quality Issue 81 Female 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea 81 Male 10/13/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 7/29/2010 65 Female 250 lb 10/21/2010 Consumer United States
Primary
Concomitant
Product Quality Issue Disability 40 Female 11/3/2010 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious Female 99 lb 11/12/2010 United States
Primary
Concomitant
Pancreatic Neoplasm Hospitalization 5/17/2010 76 Female 11/15/2010 Consumer France
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 1/1/2008 51 Female 12/1/2010 Lawyer United States
Primary
Concomitant
Uterine Cancer Other Serious 11/1/2002 76 Female 12/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia 11/1/2009 54 Female 200 lb 12/14/2010 Consumer United States
Primary
Concomitant
Aphasia Other Serious 8/4/2010 49 Female 12/20/2010 Physician United States
Primary
Concomitant
Nail Disorder Female 12/21/2010 Physician United States
Primary
Concomitant
Tremor Other Serious 12/2/2010 75 Female 155 lb 12/21/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 12/2/2010 75 Female 155 lb 12/21/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 12/2/2010 75 Female 155 lb 12/21/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 12/2/2010 75 Female 155 lb 12/21/2010 Consumer United States
Primary
Secondary
Concomitant
Uterine Cancer Other Serious 11/1/2002 76 Female 12/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 6/27/2010 71 Female 12/28/2010 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/1/2010 81 Female 1/6/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2010 81 Female 1/6/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Other Serious 11/1/2010 81 Female 1/6/2011 Consumer United States
Primary
Concomitant
Nail Disorder Female 1/7/2011 Physician United States
Primary
Concomitant
Completed Suicide Death 1/1/2009 37 Female 1/10/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 36 Female 1/10/2011 Physician United States
Primary
Secondary
Nausea 1/2/2011 55 Female 229 lb 1/6/2011 Consumer United States
Primary
Concomitant

Drug Data