Clonazepam combined with Levetiracetam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hemiparesis Hospitalization 3/13/2004 61 Female 128 lb 1/18/2006 Physician United States
Primary
Concomitant
Status Epilepticus Other Serious 5/5/2006 Female 49 lb 5/5/2006 Pharmacist United States
Primary
Concomitant
Amphetamines Positive Other Serious 3/21/2006 25 4/20/2006 Pharmacist United States
Primary
Concomitant
Fall Other Serious 6/8/2006 63 Male 8/9/2006 Pharmacist Spain
Primary
Secondary
Vitamin K Deficiency Hospitalization 5/15/2006 45 Female 8/18/2006 Consumer France
Primary
Concomitant
Stag Horn Calculus Other Serious 3/29/2005 2 Female 22 lb 8/18/2006 Physician United States
Primary
Concomitant
Anaphylactoid Reaction 7/5/2006 29 Female 8/13/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Death 7/13/2006 Male 88 lb 12/22/2006 Pharmacist United States
Primary
Concomitant
Partial Seizures Hospitalization 9/30/2006 Male 132 lb 1/27/2007 Ireland
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 Female 2/2/2007 Consumer United States
Primary
Concomitant
Transaminases Increased Other Serious 1/10/2007 Male 132 lb 2/9/2007 Physician Mexico
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/10/2007 Male 132 lb 2/23/2007 Physician Mexico
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/10/2007 Male 132 lb 3/14/2007 Physician Mexico
Primary
Secondary
Concomitant
Partial Seizures Other Serious 9/30/2006 Male 132 lb 3/26/2007 Physician Mexico
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/10/2007 Male 132 lb 3/28/2007 Physician Mexico
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 10/13/2006 Female 121 lb 4/3/2007 Netherlands
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/10/2007 Male 132 lb 4/10/2007 Physician Mexico
Primary
Secondary
Concomitant
Pseudolymphoma Other Serious Male 4/11/2007 Physician France
Primary
Concomitant
Neutropenia Hospitalization 11/23/2006 72 Female 4/25/2007 Other Health Professional France
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 7 Female 35 lb 5/11/2007 Israel
Primary
Concomitant
Visual Acuity Reduced Disability 3/7/2007 50 Female 7/2/2007 Other Health Professional France
Primary
Concomitant
Ventricular Tachycardia Required Intervention 28 Female 7/31/2007 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 50 Female 8/17/2007 Physician France
Primary
Concomitant
Vitamin B12 Increased Death 1/1/2007 36 Female 135 lb 8/30/2007 Physician United States
Primary
Secondary
Urine Ketone Body Present Death 36 Female 8/23/2007 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 36 Female 135 lb 9/13/2007 Physician United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 1/1/2007 36 Female 10/17/2007 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/1/2006 Female 11/2/2007 Physician United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/10/2007 Male 132 lb 11/21/2007 Physician Mexico
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/28/2007 52 Female 12/3/2007 Other Health Professional France
Primary
Secondary
Concomitant
Flatulence 10/24/2007 Male 148 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 6/1/2007 Female 74 lb 12/14/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 Female 2/20/2008 Consumer Australia
Primary
Concomitant
Convulsion Hospitalization 4/27/2008 45 Female 150 lb 5/14/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2006 78 Male 196 lb 5/30/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 10/17/2006 78 Male 199 lb 6/12/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 37 6/19/2008 Other Health Professional United States
Primary
Secondary
Stress Hospitalization 37 Female 7/24/2008 Switzerland
Primary
Concomitant
Pancreatitis Acute Hospitalization 4/30/2008 Male 8/27/2008 Other Health Professional France
Primary
Concomitant
Joint Sprain 5/31/2008 Male 258 lb 9/2/2008 Physician United States
Primary
Concomitant
Pyrexia 8/19/2008 Female 200 lb 9/13/2008 United States
Primary
Concomitant
Hypernatraemia Life Threatening 8/22/2008 15 Male 55 lb 9/16/2008 Physician Sweden
Primary
Concomitant
Convulsion Hospitalization 37 Female 10/21/2008 Other Health Professional Switzerland
Primary
Secondary
Drug Toxicity Death 37 12/18/2008 Physician United States
Primary
Secondary
Therapeutic Response Unexpected With Drug Substitution Other Serious 12/1/2008 Male 98 lb 1/1/2009 Other Health Professional United States
Primary
Concomitant
Visual Field Defect Other Serious 1/23/2009 Other Health Professional France
Primary
Concomitant
Drug Level Increased Death Female 169 lb 2/4/2009 Other Health Professional United States
Primary
Concomitant
Renal Tubular Disorder Other Serious 7/1/2008 10 Male 2/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious 7/1/2008 2/23/2009 Other Health Professional France
Primary
Secondary
Therapeutic Response Unexpected With Drug Substitution Other Serious 2/14/2009 Male 151 lb 2/17/2009 Physician United States
Primary
Concomitant
Somnolence Life Threatening 11/10/2008 52 Male 234 lb 3/16/2009 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia 2/2/2009 44 Female 3/30/2009 Physician Spain
Primary
Concomitant
Pulmonary Oedema Death 5/22/2009 Other Health Professional United States
Primary
Secondary
Pulmonary Oedema Death Male 5/29/2009 Other Health Professional United States
Primary
Secondary
Pancytopenia Other Serious 76 Female 5/27/2009 Physician France
Primary
Concomitant
Respiratory Distress Hospitalization Male 7 lb 6/5/2009 Physician Australia
Primary
Concomitant
Vomiting Other Serious 3/1/2009 Female 209 lb 6/1/2009 Physician Germany
Primary
Concomitant
Weight Decreased 10/24/2007 64 Male 148 lb 6/18/2009 United States
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 1/1/2007 80 Female 6/26/2009
Primary
Secondary
Concomitant
Premature Baby Hospitalization 8/8/2008 Male 7 lb 7/22/2009 Physician Australia
Primary
Concomitant
Premature Baby Hospitalization 8/8/2008 Male 7 lb 7/24/2009 Physician Australia
Primary
Concomitant
Product Substitution Issue Disability 1/1/2002 40 Male 295 lb 8/17/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Level Decreased Other Serious 10/26/2008 Male 44 lb 9/15/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 51 Female 157 lb 9/23/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 6/17/2009 Female 134 lb 7/5/2009 Pharmacist United States
Primary
Concomitant
Panic Attack Other Serious 6/1/2009 38 Female 160 lb 10/5/2009 United States
Primary
Concomitant
Weight Decreased Female 9/24/2009 Consumer United States
Primary
Secondary
Concomitant
Viral Upper Respiratory Tract Infection Required Intervention 21 Female 128 lb 10/6/2009 Switzerland
Primary
Concomitant
Thrombocytopenia Hospitalization 5/15/2005 Female 119 lb 10/26/2009 Physician France
Primary
Concomitant
Drug Ineffective Other Serious 11 Female 11/5/2009 Physician Spain
Primary
Concomitant
Drug Ineffective Other Serious 50 Male 11/5/2009 Spain
Primary
Concomitant
Weight Decreased Hospitalization 10/12/2009 Female 185 lb 11/13/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/12/2008 Female 11/20/2009 Physician United States
Primary
Concomitant
Irritability 50 Female 139 lb 12/9/2009 Consumer United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 70 Female 12/16/2009 Other Health Professional France
Primary
Secondary
Concomitant
Partial Seizures Female 37 lb 12/22/2009 Consumer
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 70 Female 12/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 40 Female 12/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Swelling Face Hospitalization 1 Female 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Hospitalization 1 Female 1/6/2010 France
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 61 Female 1/5/2010 Consumer United Kingdom
Primary
Concomitant
Swelling Face Hospitalization 1 Female 1/11/2010 United Kingdom
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 12/10/2009 Female 95 lb 1/19/2010 Other Health Professional Portugal
Primary
Concomitant
Swelling Face Hospitalization 1 Female 1/20/2010 Physician France
Primary
Secondary
Concomitant
Swelling Face Other Serious 1 Female 1/21/2010 United Kingdom
Primary
Secondary
Concomitant
Myoclonic Epilepsy Hospitalization 26 Female 1/22/2010 France
Primary
Secondary
Pancreatitis Hospitalization 70 Female 2/4/2010
Primary
Secondary
Grand Mal Convulsion Hospitalization 40 Female 2/4/2010
Primary
Secondary
Concomitant
Partial Seizures Life Threatening 11/30/2009 Female 35 lb 2/19/2010 Consumer
Primary
Secondary
Concomitant
Psychomotor Hyperactivity Other Serious 1 Male 4/12/2010
Primary
Secondary
Wound Infection Hospitalization 9/5/2009 48 Female 174 lb 4/14/2010 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 1/1/2009 45 Female 123 lb 4/19/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 36 Male 4/27/2010 Austria
Primary
Concomitant
Respiratory Distress Hospitalization Male 7 lb 5/10/2010 Physician Sweden
Primary
Concomitant
Bronchospasm Other Serious 3/23/2010 52 Male 233 lb 5/27/2010 Other Health Professional United States
Primary
Concomitant
Convulsion Death Female 101 lb 5/28/2010 Other Health Professional Singapore
Primary
Concomitant
Weight Decreased Other Serious 63 Female 6/4/2010 Physician Belgium
Primary
Concomitant
Granulocytopenia Other Serious 44 Female 180 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Convulsion Death Female 101 lb 7/6/2010 Other Health Professional Singapore
Primary
Concomitant
Pyrexia Hospitalization 1/1/2009 45 Female 123 lb 7/7/2010 Physician United States
Primary
Concomitant
Asthma Other Serious 3/23/2010 52 Male 233 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Fatigue Other Serious 34 Female 7/8/2010
Primary
Secondary
Bronchospasm Other Serious 3/23/2010 52 Male 233 lb 7/12/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/11/2010 82 Female 7/19/2010 India
Primary
Secondary
Concomitant
Weight Decreased Death Female 93 lb 7/23/2010 Other Health Professional Singapore
Primary
Concomitant
Ventricular Fibrillation Other Serious 7/14/2010 26 Female 176 lb 7/26/2010 Physician Portugal
Primary
Concomitant
Asthma Other Serious 3/23/2010 52 Male 233 lb 7/27/2010 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 7/7/2010 26 Female 176 lb 8/2/2010 Physician Portugal
Primary
Secondary
Concomitant
Nausea Other Serious 7/3/2010 40 Female 115 lb 7/28/2010 Consumer United States
Primary
Concomitant
Sensory Loss Hospitalization 65 Female 12/28/2009 Spain
Primary
Concomitant
Somnolence Other Serious 72 Male 8/4/2010 Chile
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 72 Male 8/16/2010 Chile
Primary
Secondary
Concomitant
Hyperammonaemic Encephalopathy Hospitalization 5 Male 9/3/2010 Other Health Professional India
Primary
Secondary
Concomitant
Hyperammonaemic Encephalopathy Other Serious 5 Male 9/9/2010
Primary
Secondary
Sensory Loss Hospitalization 65 Female 9/17/2010 Spain
Primary
Concomitant
Weight Increased Hospitalization 16 Male 9/29/2010 Physician United States
Primary
Secondary
Concomitant
Fatigue Hospitalization Female 10/5/2010 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 56 Female 9/29/2010 Other Health Professional France
Primary
Concomitant
Diarrhoea Haemorrhagic Other Serious 8/9/2010 5 Female 50 lb 10/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 65 Female 10/22/2010 Other Health Professional Spain
Primary
Concomitant
Hyperammonaemic Encephalopathy Hospitalization 5 Male 11/4/2010 Other Health Professional India
Primary
Secondary
Concomitant
Sensory Loss Hospitalization 65 Female 11/19/2010 Other Health Professional Spain
Primary
Concomitant
Product Substitution Issue Other Serious 12/8/2010 33 Male 148 lb 12/17/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 35 Male 12/9/2010 Physician United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 65 Female 12/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 65 Female 12/26/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Sensory Loss Hospitalization 65 Female 12/30/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2009 29 Male 1/7/2011 Physician United States
Primary
Secondary
Fall Hospitalization 65 Female 1/7/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/27/2010 30 Male 1/11/2011 Physician France
Primary
Concomitant
Completed Suicide Death 29 Male 1/19/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 29 Male 1/21/2011 Physician United States
Primary
Secondary
Platelet Disorder Other Serious 35 Male 1/24/2011 Other Health Professional United States
Primary
Concomitant
Speech Disorder Other Serious 21 Female 1/25/2011 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 35 Male 1/26/2011
Primary
Secondary
Concomitant
Amnesia Hospitalization 7/3/2010 40 Female 97 lb 1/12/2011 Consumer United States
Primary
Concomitant
Feeling Abnormal 1/1/2005 59 Male 210 lb 1/19/2011 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 21 Female 1/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Muscle Twitching Other Serious 21 Female 1/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Convulsion Other Serious 48 Male 2/1/2011 Physician
Primary
Concomitant
Cardiac Arrest Death 29 Male 1/14/2011 United States
Primary
Secondary
Anaemia Other Serious 35 Male 2/1/2011 Other Health Professional United States
Primary
Secondary
Haematuria Other Serious 35 Male 2/3/2011 Other Health Professional United States
Primary
Secondary
Fear Other Serious 21 Female 2/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Toxicity To Various Agents Death 1/1/2009 29 Male 2/3/2011 Physician United States
Primary
Secondary
Grand Mal Convulsion Other Serious 21 Female 2/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Nervousness Other Serious 21 Female 2/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Completed Suicide Death 1/1/2009 29 Male 1/27/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2009 29 Male 1/25/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 29 Male 1/26/2011 Other Health Professional United States
Primary
Secondary

Drug Data