Clonazepam combined with Lamotrigine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 1/6/2006 50 Male 110 lb 1/19/2006 Pharmacist United States
Primary
Concomitant
Anger Hospitalization 8/18/2005 43 Male 1/20/2006 Australia
Primary
Secondary
Concomitant
Menorrhagia Hospitalization 10/2/2005 47 Female 2/15/2006 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 52 Female 2/17/2006 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/25/2006 38 Female 2/22/2006 Slovakia (Slovak Republic)
Primary
Secondary
Missed Labour Other Serious 6/23/2005 31 Female 3/14/2006 Physician Poland
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2005 62 Female 12/14/2005 Physician United States
Primary
Concomitant
Wrong Drug Administered Other Serious 3/1/2005 36 Male 2/8/2006 United Kingdom
Primary
Secondary
Concomitant
Purpura Other Serious 46 Female 211 lb 4/14/2006 Other Health Professional United States
Primary
Concomitant
Purpura Other Serious 46 Female 211 lb 4/14/2006 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 2/28/2006 61 Male 5/12/2006 Other Health Professional France
Primary
Concomitant
Interacting
Vomiting Hospitalization 2/1/2005 Male 5/26/2006 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/1995 31 Female 3/21/2005 United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 10/28/2005 55 Male 126 lb 6/2/2006 Physician Brazil
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 12/31/2005 Female 152 lb 6/26/2006 Pharmacist United States
Primary
Secondary
Concomitant
Mania Other Serious 45 Male 7/26/2006 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2006 44 Male 9/5/2006 Physician Czech Republic
Primary
Concomitant
Status Epilepticus Hospitalization 8/26/2006 29 Male 9/25/2006 Other Health Professional Ireland
Primary
Concomitant
Splenomegaly Hospitalization 8/23/2006 4 Female 10/9/2006 Consumer Croatia (Local Name: Hrvatska)
Primary
Concomitant
Drug Dispensing Error Other Serious 6/1/2006 40 Male 10/13/2006 Consumer France
Primary
Concomitant
Intentional Overdose Death 7/25/2006 23 Female 150 lb 10/26/2006 Physician Russian Federation
Primary
Concomitant
Hepatic Lesion Life Threatening 7/1/2006 36 Female 10/27/2006 Other Health Professional France
Primary
Secondary
Drug Ineffective Other Serious Female 10/26/2006 Brazil
Primary
Concomitant
Overweight Other Serious Female 143 lb 11/3/2006 Brazil
Primary
Concomitant
Poisoning Death 48 11/17/2006 Physician United States
Primary
Secondary
Vomiting Hospitalization 10 Female 12/11/2006 Consumer Israel
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2002 Female 12/21/2006 Consumer United States
Primary
Secondary
Concomitant
Interacting
Tachycardia Other Serious Female 1/4/2007 Consumer Ireland
Primary
Secondary
Respiratory Distress Hospitalization 64 Male 12/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 64 Male 12/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 8/8/2006 Male 8/15/2006 Pharmacist United States
Primary
Concomitant
Unevaluable Event Other Serious 11/5/2006 Male 156 lb 2/12/2007 Physician France
Primary
Concomitant
Death Death 1/1/2005 48 Unknown 2/8/2007 Physician United States
Primary
Secondary
Large Intestine Perforation Death 12/27/2006 12 Male 2/16/2007 Physician Netherlands
Primary
Concomitant
Pneumonia Hospitalization 1/21/2007 Male 3/2/2007 Other Health Professional France
Primary
Secondary
Concomitant
Verbigeration Required Intervention 35 Female 3/5/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/10/2007 48 Female 3/26/2007 Physician Korea, Republic Of
Primary
Concomitant
Thinking Abnormal Hospitalization 35 Female 3/27/2007 Physician United States
Primary
Concomitant
Nicotine Dependence Other Serious 55 Male 5/25/2007 Consumer United States
Primary
Secondary
Concomitant
Mania 1/1/2006 59 Female 270 lb 4/12/2007 Consumer United States
Primary
Concomitant
Malabsorption Other Serious 8/1/2006 Female 6/7/2007 Physician France
Primary
Secondary
Concomitant
Nicotine Dependence Other Serious 55 Male 6/11/2007 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 22 Female 6/13/2007 Other Health Professional Canada
Primary
Secondary
Tremor Other Serious 22 Female 6/21/2007 Other Health Professional Canada
Primary
Secondary
Somnolence Other Serious 2/1/2007 Female 6/29/2007 Pharmacist Canada
Primary
Concomitant
Status Epilepticus Hospitalization 8/26/2006 29 Male 8/10/2007 Other Health Professional Ireland
Primary
Concomitant
Status Epilepticus Hospitalization 8/26/2006 29 Male 9/13/2007 Other Health Professional Ireland
Primary
Concomitant
Pseudophaeochromocytoma Other Serious 31 Female 9/26/2007 Other Health Professional New Zealand
Primary
Concomitant
Transaminases Increased Hospitalization 2 Female 9/22/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 8/26/2006 29 Male 9/28/2007 Other Health Professional Ireland
Primary
Concomitant
Completed Suicide Death 48 10/29/2007 Physician United States
Primary
Secondary
Convulsion Other Serious 11/1/2006 6 Male 42 lb 10/1/2007 United States
Primary
Concomitant
Restlessness Required Intervention Female 11/14/2007 Physician United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 27 Female 12/3/2007 United States
Primary
Concomitant
Hepatotoxicity Hospitalization 2 Female 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Drug Toxicity Death 52 Male 1/11/2008 Physician United States
Primary
Secondary
Drug Toxicity Death 53 Female 1/14/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 52 Male 1/21/2008 United States
Primary
Secondary
Completed Suicide Death 50 Male 1/21/2008 United States
Primary
Secondary
Accidental Exposure Death 53 Female 1/21/2008 United States
Primary
Secondary
Poisoning Death 53 Female 1/21/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 52 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 52 Male 1/22/2008 Physician United States
Primary
Secondary
Death Death 44 Male 1/21/2008 Physician United States
Primary
Secondary
Tooth Extraction Disability 64 Female 1/29/2008 Pharmacist Canada
Primary
Concomitant
Death Death 1/29/2008 Physician United States
Primary
Secondary
Death Death 53 Female 1/31/2008 Physician United States
Primary
Secondary
Completed Suicide Death 50 Male 1/31/2008 Physician United States
Primary
Secondary
Death Death 44 Male 1/31/2008 Physician United States
Primary
Secondary
Death Death 1/1/2006 44 Male 2/12/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 52 Male 2/13/2008 Physician United States
Primary
Secondary
Death Death 1/1/2006 50 Male 2/13/2008 Physician United States
Primary
Secondary
Death Death 1/1/2006 53 Female 2/12/2008 Physician United States
Primary
Secondary
Death Death 53 Female 2/15/2008 Physician United States
Primary
Concomitant
Multiple Drug Overdose Intentional Death 44 Male 2/28/2008 United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 45 Male 2/29/2008 United States
Primary
Concomitant
Neoplasm Recurrence Other Serious 7/12/2005 Male 19 lb 3/5/2008 France
Primary
Concomitant
Weight Increased Other Serious 36 Female 3/6/2008 Physician United States
Primary
Concomitant
Rash Generalised Other Serious 20 Male 3/9/2008 Consumer
Primary
Secondary
Concomitant
Staphylococcal Infection 8/16/2007 Female 3/14/2008 Physician United States
Primary
Secondary
Concomitant
Somnolence 12/21/2007 Female 172 lb 3/14/2008 Consumer United States
Primary
Concomitant
Injection Site Urticaria 1/23/2008 Female 140 lb 3/15/2008 United States
Primary
Concomitant
Liver Injury Other Serious 3/25/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Speech Disorder Disability 2/14/2008 20 Female 3/27/2008 Consumer United Kingdom
Primary
Concomitant
Completed Suicide Death 3/27/2008 Physician United States
Primary
Secondary
Epilepsy Other Serious 12/15/2007 29 Male 3/28/2008 Other Health Professional France
Primary
Concomitant
Interacting
Vomiting Hospitalization 3/26/2008 35 Female 132 lb 4/1/2008 Pharmacist United States
Primary
Concomitant
Tremor Disability 14 Male 4/3/2008 France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 20 Male 4/9/2008 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred 7/1/2007 Female 182 lb 4/11/2008 Consumer United States
Primary
Concomitant
Pelvic Fracture Other Serious 3/1/2008 31 Female 5/7/2008 Consumer United States
Primary
Concomitant
Inhibitory Drug Interaction Other Serious 1/1/2008 2 Female 5/12/2008 Netherlands
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 11/22/2002 32 Female 5/21/2008 Physician United Kingdom
Primary
Concomitant
Drug Toxicity Hospitalization 36 Male 5/22/2008 Consumer Brazil
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 10/31/2007 Male 5/22/2008 Physician France
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 2 Female 6/2/2008 Other Health Professional Netherlands
Primary
Concomitant
Drug Eruption Hospitalization 12/1/2007 36 Male 187 lb 6/3/2008 Physician Switzerland
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 6/12/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia 4/24/2008 Female 137 lb 6/13/2008 United States
Primary
Concomitant
Skin Atrophy 1/1/2007 Female 165 lb 6/13/2008 Consumer United States
Primary
Concomitant
Contusion 5/1/2008 Female 6/13/2008 United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 38 Male 198 lb 6/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Adverse Reaction Death 44 Male 6/19/2008 Physician United States
Primary
Secondary
Respiratory Arrest Other Serious 52 Male 6/19/2008 Physician United States
Primary
Secondary
Death Death 53 Female 6/19/2008 Physician United States
Primary
Secondary
Overdose Death 50 Male 6/19/2008 Physician United States
Primary
Secondary
Withdrawal Syndrome Other Serious 11/22/2002 32 Female 6/23/2008 Physician United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 45 Male 6/27/2008 United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 7/10/2008 Other Health Professional United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 6/1/2008 72 Male 7/14/2008 Pharmacist Canada
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 6/30/2008 Male 7/18/2008 Pharmacist Canada
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 198 lb 8/7/2008 Pharmacist United Kingdom
Primary
Concomitant
Pregnancy With Implant Contraceptive 1/1/2007 36 Female 8/19/2008 Australia
Primary
Concomitant
Simple Partial Seizures Other Serious 7/25/2008 26 Female 8/22/2008 Other Health Professional South Africa
Primary
Concomitant
Dystonia Other Serious 12/1/2007 61 Female 8/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus 5/1/2008 Female 222 lb 8/29/2008 Consumer United States
Primary
Concomitant
Visual Impairment 4/1/2008 Female 175 lb 9/2/2008 Consumer United States
Primary
Concomitant
Rib Fracture Other Serious 8/1/2008 37 Male 9/8/2008 Consumer United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 9/8/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 8/1/2007 Female 240 lb 9/12/2008 United States
Primary
Concomitant
Pain 4/25/2008 Female 9/12/2008 United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 10/2/2004 50 Male 9/10/2008 Denmark
Primary
Concomitant
Delirium Hospitalization 41 Female 9/23/2008 Physician United States
Primary
Secondary
Weight Increased Other Serious 8/1/2007 22 Male 9/24/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2008 Female 10/28/2008 Physician United States
Primary
Concomitant
Pregnancy With Implant Contraceptive 1/1/2007 36 Female 11/5/2008 Australia
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 1/1/2008 24 Male 10/7/2008 United States
Primary
Secondary
Visual Impairment Other Serious 1/1/2006 Female 130 lb 11/17/2008 Consumer United States
Primary
Concomitant
Dysphagia 9/21/2008 Female 11/26/2008 United States
Primary
Concomitant
Completed Suicide Death 37 Male 12/19/2008 Physician United States
Primary
Secondary
Tachypnoea Other Serious 10/5/2008 Female 225 lb 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2007 37 Male 12/24/2008 Physician United States
Primary
Secondary
Completed Suicide Death 37 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Somnolence Life Threatening 11/10/2008 Male 234 lb 12/16/2008 Other Health Professional United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious Female 1/12/2009 Consumer Canada
Primary
Concomitant
Swelling Other Serious 12/4/2008 66 Male 1/14/2009 Consumer South Africa
Primary
Concomitant
Tachypnoea Other Serious 47 Female 1/12/2009 Physician
Primary
Concomitant
Tachypnoea Other Serious 47 Female 1/9/2009 United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2007 37 Male 1/15/2009 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2007 40 Male 1/15/2009 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 37 Male 1/16/2009 United States
Primary
Secondary
Rash Disability 6/1/2008 73 Female 1/13/2009 Physician United States
Primary
Concomitant
Drug Toxicity Death 40 Male 1/20/2009 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 50 Male 1/20/2009 Other Health Professional United States
Primary
Secondary
Lower Respiratory Tract Infection Hospitalization 11/1/2008 Female 188 lb 1/22/2009 Consumer United Kingdom
Primary
Concomitant
Respiratory Arrest Other Serious 37 Male 1/23/2009 Physician United States
Primary
Secondary
Death Death 40 Male 1/23/2009 Physician United States
Primary
Secondary
Hepatic Steatosis 61 Female 1/16/2009 Physician Canada
Primary
Concomitant
Petit Mal Epilepsy Other Serious 23 Female 1/26/2009 Consumer Canada
Primary
Concomitant

Drug Data