Clonazepam combined with Hydromorphone Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Pain Hospitalization 57 Female 2/10/2006 Other Health Professional Canada
Primary
Concomitant
Restless Legs Syndrome Required Intervention 1/19/2005 61 Female 5/16/2006 Pharmacist United States
Primary
Secondary
Tachycardia Required Intervention 4/21/2006 59 Male 159 lb 6/1/2006 Pharmacist United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/8/2004 47 Female 118 lb 8/28/2006 Physician Canada
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 42 Male 420 lb 10/30/2006 Physician United States
Primary
Concomitant
Respiratory Distress Required Intervention 8/2/2006 59 Female 8/29/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Required Intervention 8/1/2006 Male 8/7/2006 Pharmacist United States
Primary
Concomitant
Convulsion Other Serious 28 Female 3/23/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Sleep Walking Other Serious 1/4/2003 Female 4/13/2007 Consumer United States
Primary
Concomitant
Tremor Other Serious 37 Male 6/15/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 4/1/2007 41 Female 8/2/2007 Physician United States
Primary
Concomitant
Stress Other Serious 10/9/2000 Female 132 lb 8/3/2007 Physician United States
Primary
Concomitant
Methaemoglobinaemia Hospitalization Female 125 lb 8/24/2007 United States
Primary
Concomitant
Vision Blurred Other Serious 2/21/2007 Female 260 lb 10/5/2007 Canada
Primary
Concomitant
Wheezing Hospitalization 10/13/2004 40 Female 3/7/2008 Physician United States
Primary
Concomitant
Wheezing Hospitalization 10/13/2004 40 Female 3/11/2008 Physician United States
Primary
Concomitant
Wheezing Hospitalization 10/13/2004 40 Female 3/28/2008 Physician United States
Primary
Concomitant
Wheezing Hospitalization 10/13/2004 40 Female 4/4/2008 Physician United States
Primary
Concomitant
Wheezing Hospitalization 10/13/2004 40 Female 4/8/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 35 Male 4/15/2008 Physician United States
Primary
Concomitant
Angioedema Other Serious 8/26/2007 40 Female 6/20/2008 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 6/1/2008 Female 164 lb 7/8/2008 Consumer United States
Primary
Concomitant
Rash Generalised 7/8/2008 Female 7/9/2008 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 6/1/2008 Female 164 lb 8/6/2008 Physician United States
Primary
Concomitant
Wheezing Hospitalization 10/13/2004 40 Female 8/11/2008 Physician United States
Primary
Concomitant
Drug Interaction Hospitalization 60 Male 9/5/2008 Other Health Professional Belgium
Primary
Concomitant
Interacting
Treatment Failure Other Serious 24 Female 9/11/2008 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2005 Male 183 lb 9/26/2008 Physician United States
Primary
Concomitant
Somnolence Life Threatening 60 Male 10/8/2008 Other Health Professional United States
Primary
Secondary
Neoplasm Progression Required Intervention 8/15/2007 45 Female 175 lb 9/26/2007 Physician United States
Primary
Concomitant
Potentiating Drug Interaction Life Threatening 1/1/2008 60 Male 10/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Wheezing Hospitalization 10/13/2004 40 Female 11/18/2008 Physician United States
Primary
Concomitant
Platelet Count Increased Required Intervention 8/30/2008 66 Female 287 lb 10/3/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 60 Female 180 lb 12/2/2008 United States
Primary
Concomitant
Wheezing Hospitalization 10/13/2004 40 Female 12/12/2008 Physician United States
Primary
Concomitant
Respiratory Acidosis Hospitalization 11/1/2008 75 Female 1/9/2009 Consumer Switzerland
Primary
Concomitant
Interacting
Respiratory Acidosis Hospitalization 11/1/2008 1/15/2009 Physician Switzerland
Primary
Secondary
Concomitant
Respiratory Acidosis Hospitalization 11/1/2008 1/22/2009 Physician Switzerland
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 6/1/2005 43 Male 183 lb 2/19/2009 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/22/2008 30 Female 2/18/2009 Physician United States
Primary
Concomitant
Myalgia Other Serious 11/13/2008 Female 3/12/2009 Physician Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 1/1/2003 36 Female 4/6/2009 United States
Primary
Concomitant
Vomiting Hospitalization 3/20/2009 39 Female 117 lb 4/6/2009 Consumer United States
Primary
Concomitant
Myoclonus Other Serious 46 Female 4/6/2009 Other Health Professional United States
Primary
Secondary
Pain Hospitalization 4/2/2009 Male 4/2/2009 United States
Primary
Concomitant
Vomiting Hospitalization 3/1/2009 39 Female 117 lb 4/10/2009 Other Health Professional United States
Primary
Concomitant
Tendonitis Disability 8/18/2008 4/24/2009 Canada
Primary
Concomitant
Tendonitis Disability 8/18/2008 4/27/2009 Canada
Primary
Concomitant
Vomiting Hospitalization 3/1/2009 39 Female 117 lb 5/11/2009 Other Health Professional United States
Primary
Concomitant
Wound Hospitalization 2/10/2002 40 Male 194 lb 5/20/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 4/25/2009 58 Female 192 lb 4/27/2009 Pharmacist United States
Primary
Concomitant
Pseudocyst Other Serious 1/1/2005 36 Female 140 lb 7/9/2009 United States
Primary
Concomitant
Renal Failure Chronic Other Serious 5/21/2000 46 Male 260 lb 7/10/2009 United States
Primary
Concomitant
Vomiting Other Serious 6/15/2009 Male 195 lb 7/13/2009 Canada
Primary
Concomitant
Vomiting Other Serious 6/15/2009 Male 195 lb 7/14/2009 Canada
Primary
Concomitant
Tooth Disorder Other Serious 3/24/2009 53 Male 7/27/2009 Physician Canada
Primary
Concomitant
Convulsion Other Serious 1 Female 7/28/2009 Physician United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 6/27/2009 41 Female 8/5/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 11/1/2006 Female 8/13/2009 Consumer United States
Primary
Concomitant
Facial Paresis Other Serious 1/1/2008 45 Female 8/16/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 11 Female 49 lb 11/12/2009 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Hospitalization 10/15/2008 Female 183 lb 11/20/2009 Physician
Primary
Secondary
Concomitant
Urticaria Other Serious 8/1/2008 Female 126 lb 11/23/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 56 Female 11/18/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/15/2008 47 Female 183 lb 12/2/2009 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2005 Male 183 lb 11/30/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/15/2008 47 Female 183 lb 12/2/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/13/2004 40 Female 12/15/2009 Physician United States
Primary
Concomitant
Unresponsive To Stimuli 10/31/2009 79 Female 1/20/2010 Pharmacist United States
Primary
Secondary
Concomitant
Pseudocyst Other Serious 1/1/2000 31 Female 140 lb 3/8/2010 United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2008 21 Male 3/12/2010 Physician United States
Primary
Secondary
Restlessness Other Serious 1/13/2010 53 Female 130 lb 3/23/2010 Physician Canada
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 44 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2006 Female 3/24/2010 Consumer United States
Primary
Concomitant
Serotonin Syndrome Other Serious 44 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Serotonin Syndrome Other Serious 44 Female 3/26/2010
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Hesitation Hospitalization 1/1/2002 36 Male 196 lb 3/22/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 44 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Urinary Hesitation Hospitalization 1/1/2002 36 Male 196 lb 4/12/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Serotonin Syndrome Other Serious 44 Female 4/15/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 10/1/2009 54 Female 172 lb 4/23/2010 Pharmacist United States
Primary
Concomitant
Splenomegaly Hospitalization 3/7/2008 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 44 Female 5/10/2010 Consumer United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 6/7/2010 Physician United States
Primary
Secondary
Concomitant
Surgery Other Serious 2/21/2010 56 Male 278 lb 6/11/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 10/15/2008 47 Female 183 lb 9/20/2010 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 52 Male 9/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/15/2008 64 Female 181 lb 10/3/2010 United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 3/1/2008 28 Female 168 lb 10/7/2010 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 8/31/2010 28 Female 10/25/2010 Physician United States
Primary
Concomitant
Yellow Skin 11/1/2010 61 Female 12/29/2010 Consumer Canada
Primary
Concomitant
Toxicity To Various Agents Death 70 Female 1/4/2011 Other Health Professional United States
Primary
Secondary
Intervertebral Disc Degeneration Hospitalization 9/28/2010 53 Female 212 lb 1/5/2011 Physician United States
Primary
Concomitant
Completed Suicide Death 1/1/2009 70 Female 1/7/2011 Physician United States
Primary
Secondary
Completed Suicide Death 70 Female 1/11/2011 Other Health Professional United States
Primary
Secondary
Livedo Reticularis Death 8/25/2010 67 Male 163 lb 1/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Ulcer Hospitalization 1/1/1999 52 Female 1/12/2011 Physician Canada
Primary
Concomitant
Completed Suicide Death 70 Female 1/13/2011
Primary
Secondary
Toxicity To Various Agents Death 1/1/2009 70 Female 1/19/2011 Other Health Professional United States
Primary
Secondary
Confusional State Other Serious 8/25/2010 67 Male 163 lb 2/2/2011 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 70 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Gastritis Other Serious 6/1/2009 20 Female 181 lb 2/15/2011 Consumer United States
Primary
Concomitant
Herpes Zoster Other Serious 2/24/2011 63 Male 3/1/2011 Pharmacist Canada
Primary
Concomitant
Completed Suicide Death 70 Female 3/8/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 70 Female 3/11/2011 Physician United States
Primary
Secondary
Vision Blurred 9/1/2010 61 Female 183 lb 3/14/2011 Physician Canada
Primary
Concomitant
Toxicity To Various Agents Death 70 Female 3/24/2011 Physician United States
Primary
Secondary
Abnormal Behaviour Hospitalization 10/20/2010 44 Male 3/28/2011 Consumer United States
Primary
Concomitant
Malnutrition Hospitalization Female 4/14/2011 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/21/2003 Male 6/1/2011 United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 11/25/2010 57 Female 5/31/2011 Consumer United States
Primary
Concomitant
Bk Virus Infection Hospitalization 10/4/2010 47 Male 295 lb 6/27/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Dehydration Hospitalization 10/4/2010 47 Male 295 lb 7/5/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 2/24/2011 71 Male 7/4/2011 Pharmacist Canada
Primary
Concomitant
Pyrexia Death 1/1/2008 60 Female 7/11/2011 Physician United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Other Serious 6/15/2011 47 Female 189 lb 6/28/2011 Consumer United States
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 10/4/2010 47 Male 295 lb 7/26/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/1/2009 61 Female 7/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 67 Female 251 lb 8/2/2011 Other Health Professional Canada
Primary
Concomitant
Abdominal Pain Other Serious 6/1/2009 20 Female 181 lb 8/12/2011 Consumer United States
Primary
Concomitant
Hepatic Failure Hospitalization 6/16/2011 23 Male 307 lb 8/18/2011 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 3/1/2011 30 Female 130 lb 8/30/2011 Physician United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 11/25/2010 57 Female 9/7/2011 Consumer United States
Primary
Concomitant
Sedation Hospitalization 67 Female 251 lb 9/16/2011 Other Health Professional Canada
Primary
Concomitant
Tooth Fracture Other Serious 11/25/2010 57 Female 10/13/2011 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Death 3/3/2007 41 Female 176 lb 10/24/2011 Physician United States
Primary
Concomitant
Bronchitis 12/14/2010 60 Female 175 lb 10/28/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 8/1/2009 46 Female 134 lb 10/31/2011 Physician France
Primary
Secondary
Concomitant
Hypercholesterolaemia Hospitalization 5/1/2008 41 Female 225 lb 11/9/2011 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/24/2011 50 Female 216 lb 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Death Disability 1/1/2009 60 Male 11/28/2011 Physician United States
Primary
Concomitant
Dehydration Other Serious 6/15/2011 47 Female 189 lb 11/23/2011 Consumer United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 10/26/2009 16 Male 169 lb 12/13/2011 Consumer United States
Primary
Secondary
Concomitant
Large Intestinal Ulcer Other Serious 12/11/2009 53 Female 145 lb 12/13/2011 Lawyer United States
Primary
Concomitant
Dysstasia Hospitalization 6/15/2011 47 Female 189 lb 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 11/25/2010 57 Female 12/27/2011 Consumer United States
Primary
Concomitant
Chest Pain Death 5/17/2011 73 Male 1/12/2012 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 4/23/2011 73 Male 1/17/2012 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2006 59 Male 227 lb 2/2/2012 Physician Canada
Primary
Concomitant
Toxicity To Various Agents Death 1/9/2010 52 Female 134 lb 2/3/2012 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 1/9/2010 52 Female 134 lb 2/3/2012 Consumer United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 1/9/2010 52 Female 134 lb 2/3/2012 Physician United States
Primary
Secondary
Concomitant
Overdose Death 1/9/2010 52 Female 134 lb 2/3/2012 Consumer United States
Primary
Secondary
Concomitant

Drug Data