Clonazepam combined with Fentanyl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Mental Status Changes Hospitalization 10/5/2005 Male 1/19/2006 Pharmacist United States
Primary
Concomitant
Femur Fracture Hospitalization 1/8/2006 Female 135 lb 1/26/2006 Canada
Primary
Concomitant
Supraventricular Extrasystoles Hospitalization 12/15/2005 72 Male 2/16/2006 Consumer France
Primary
Secondary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 2/28/2006 Physician Brazil
Primary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 3/13/2006 Physician Brazil
Primary
Concomitant
Coma Life Threatening 2/6/2006 70 Female 132 lb 3/21/2006 Physician France
Primary
Concomitant
West Nile Viral Infection Other Serious Female 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Disorder Hospitalization 9/30/2004 63 Male 240 lb 4/17/2006 United States
Primary
Concomitant
Urinary Retention Hospitalization 9/30/2004 63 Male 240 lb 5/5/2006 United States
Primary
Concomitant
Homicide Death 1/1/2000 26 Male 5/12/2006 Consumer United States
Primary
Secondary
Drug Withdrawal Syndrome Hospitalization 9/14/2005 36 Male 247 lb 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/28/2006 59 Male 180 lb 4/28/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 7/1/2006 Male 7/24/2006 Physician France
Primary
Concomitant
Rectal Haemorrhage Other Serious 7/13/2005 56 Female 8/3/2006 Physician United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 7/13/2005 56 Female 8/3/2006 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 3/1/2006 Female 180 lb 8/18/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious Male 9/7/2006 Physician Canada
Primary
Concomitant
Rectal Haemorrhage Other Serious 7/13/2005 56 Female 9/7/2006 United States
Primary
Concomitant
Multiple Drug Overdose Death 20 Male 9/13/2006 Physician United States
Primary
Secondary
Multiple Drug Overdose Death 20 Male 9/14/2006 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 19 Male 9/15/2006 Physician United States
Primary
Secondary
White Blood Cell Count Increased Other Serious Male 9/18/2006 Physician Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious Male 10/4/2006 Physician Canada
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 8/29/2006 44 Female 118 lb 10/31/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 9/30/2004 63 Male 240 lb 11/7/2006 United States
Primary
Concomitant
Respiratory Arrest Death 20 NotSpecified 11/17/2006 Physician United States
Primary
Secondary
Weight Decreased Hospitalization 9/30/2004 63 Male 240 lb 11/20/2006 United States
Primary
Concomitant
Tachycardia Death 20 Male 12/4/2006 Physician United States
Primary
Secondary
Nausea Other Serious 8/24/2006 Female 175 lb 12/19/2006 Physician United States
Primary
Concomitant
Leukocytosis Hospitalization 11/8/2006 74 Male 1/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Drug Abuser Death 20 1/24/2007 Physician United States
Primary
Secondary
Vomiting Neonatal Hospitalization 1/14/2003 Male 2/9/2007 Physician Japan
Primary
Secondary
Serotonin Syndrome Life Threatening 1/1/2007 54 Male 2/13/2007 Physician Spain
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 3/24/2006 Female 115 lb 3/16/2007 Physician France
Primary
Concomitant
Platelet Count Decreased Required Intervention 11/7/2006 54 Female 119 lb 12/11/2006 Pharmacist United States
Primary
Concomitant
Suicide Attempt Other Serious 4/28/2004 Female 5/8/2007 Lawyer United States
Primary
Secondary
Pharyngolaryngeal Pain Female 2/22/2007 United States
Primary
Concomitant
Overdose 6/28/2007 55 Female 7/16/2007 Physician Netherlands
Primary
Concomitant
Rash Erythematous Hospitalization 7/24/2007 16 Female 9/4/2007 Other Health Professional France
Primary
Secondary
Concomitant
Premature Baby Other Serious 0 Female 5 lb 9/4/2007
Primary
Secondary
Concomitant
Sedation Other Serious 36 Female 9/19/2007 Spain
Primary
Concomitant
Incorrect Dose Administered Hospitalization 10/16/2007 Male 289 lb 10/16/2007 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Other Serious 20 10/29/2007 Physician United States
Primary
Secondary
Respiratory Arrest Other Serious 7/1/2007 Female 190 lb 11/1/2007 Physician United States
Primary
Concomitant
Wound Infection Death Male 115 lb 12/4/2007 United States
Primary
Concomitant
Viral Infection 7/1/2007 Female 12/10/2007 Consumer United States
Primary
Concomitant
Renal Tubular Acidosis Hospitalization Male 12/20/2007 Pharmacist Canada
Primary
Concomitant
Drug Toxicity Death 46 Female 1/14/2008 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Hospitalization 11/4/2007 47 Female 145 lb 1/10/2008 United States
Primary
Concomitant
Dental Caries Other Serious 12/2/2007 Female 1/18/2008 Pharmacist Canada
Primary
Concomitant
Narcotic Intoxication Death 1/1/2002 32 Female 1/30/2008 Physician Canada
Primary
Secondary
Concomitant
Drug Toxicity Death 1/1/2004 45 1/30/2008 Physician Canada
Primary
Secondary
Narcotic Intoxication Death 1/1/2002 32 Female 1/31/2008 Physician Canada
Primary
Secondary
Concomitant
Drug Toxicity Death 1/1/2004 45 1/31/2008 Physician Canada
Primary
Secondary
Respiratory Arrest Death 20 Female 1/31/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 36 Female 1/31/2008 Physician United States
Primary
Secondary
Completed Suicide Death 71 Male 1/31/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 46 Female 1/31/2008 Physician United States
Primary
Secondary
Completed Suicide Death 71 Male 2/8/2008 United States
Primary
Secondary
Completed Suicide Death 71 Male 2/6/2008 Physician United States
Primary
Secondary
Completed Suicide Death 46 Female 2/6/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 36 Female 2/6/2008 Physician United States
Primary
Secondary
Drug Abuse Death 20 Female 2/6/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 20 Female 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 36 Female 2/13/2008 Physician United States
Primary
Secondary
Death Death 1/1/2006 71 Male 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 46 Female 2/13/2008 Physician United States
Primary
Secondary
Pitting Oedema Hospitalization 8/20/2006 60 Female 264 lb 3/6/2008 United States
Primary
Concomitant
Fatigue Female 200 lb 3/15/2008 United States
Primary
Concomitant
Completed Suicide Death 3/27/2008 Physician United States
Primary
Secondary
Renal Tubular Acidosis Hospitalization Male 3/31/2008 Pharmacist Canada
Primary
Concomitant
Toxic Encephalopathy Hospitalization 49 Female 4/17/2008 Physician Canada
Primary
Secondary
Concomitant
Sinus Congestion Hospitalization 2/1/2008 58 Female 5/6/2008 Physician Canada
Primary
Concomitant
Urinoma Hospitalization 39 Female 5/8/2008 United Kingdom
Primary
Secondary
Urinary Tract Infection Hospitalization 1/1/2007 Female 71 lb 5/21/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/6/2007 56 Female 115 lb 5/19/2008 Physician Japan
Primary
Concomitant
Subacute Combined Cord Degeneration Hospitalization 2/1/2008 58 Female 5/30/2008 Physician Canada
Primary
Concomitant
Respiratory Arrest Death 20 Female 6/18/2008 Physician United States
Primary
Secondary
Shoulder Operation Other Serious 6/19/2008 Female 138 lb 6/27/2008 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 4/18/2008 46 Female 7/1/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Hospitalization 6/19/2008 Female 138 lb 7/11/2008 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 1/1/2007 56 Female 190 lb 7/25/2008 Consumer United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 1/1/2007 56 Female 190 lb 7/25/2008 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 7/14/2008 61 Male 200 lb 8/13/2008 United States
Primary
Concomitant
Vomiting Hospitalization 9/6/2008 52 Female 181 lb 9/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/6/2008 52 Female 181 lb 9/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Female 145 lb 9/12/2008 United States
Primary
Concomitant
Urinoma Other Serious 39 Female 115 lb 9/24/2008
Primary
Secondary
Concomitant
Toxic Encephalopathy Required Intervention 49 Female 9/22/2008 Canada
Primary
Secondary
Concomitant
Urinoma Other Serious 39 Female 115 lb 10/3/2008
Primary
Secondary
Concomitant
Thinking Abnormal Hospitalization 9/8/2008 60 Female 155 lb 10/30/2008 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious Female 11/18/2008 Physician Canada
Primary
Concomitant
Pulmonary Embolism Life Threatening 5/4/2007 Female 11/24/2008 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Required Intervention 9/19/2006 57 Male 11/12/2008 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 5/4/2007 Female 12/1/2008 Physician United States
Primary
Concomitant
Angina Unstable Other Serious 7/9/2001 Male 194 lb 1/8/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 Female 207 lb 1/13/2009 Physician United States
Primary
Concomitant
Personality Disorder 57 Female 117 lb 1/13/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 10/19/2008 67 Male 1/14/2009 France
Primary
Secondary
Concomitant
Angina Unstable Other Serious 7/9/2001 Male 194 lb 1/24/2009 Physician United States
Primary
Concomitant
Cardio-respiratory Arrest Death 1/1/2007 32 Male 2/3/2009 Pharmacist United States
Primary
Secondary
Weight Decreased Hospitalization 10/19/2008 67 Male 1/29/2009 Physician France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/19/2008 67 Male 2/9/2009 France
Primary
Secondary
Concomitant
Somnolence Other Serious 60 Male 3/3/2009 Pharmacist Japan
Primary
Concomitant
Vomiting Hospitalization 9/22/2008 30 Female 2/18/2009 Physician United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 12/18/2007 Female 153 lb 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 2/1/2009 54 Female 220 lb 4/23/2009 Consumer United States
Primary
Concomitant
Hallucination Hospitalization 4/18/2009 Male 319 lb 5/7/2009 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 2/1/2009 54 Female 220 lb 5/13/2009 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 11/1/2003 39 Female 5/20/2009 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 10/1/2008 Female 230 lb 5/20/2009 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 3/14/2009 78 Female 6/5/2009 France
Primary
Secondary
Concomitant
Visual Impairment Required Intervention 4/23/2009 41 Female 100 lb 5/5/2009 Pharmacist United States
Primary
Concomitant
Death Death 9/14/2008 58 7/7/2009 Physician Japan
Primary
Concomitant
Wheezing Other Serious 1/1/2008 Female 230 lb 7/7/2009 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2007 37 Female 146 lb 7/15/2009 Other Health Professional United States
Primary
Concomitant
Overdose Other Serious 55 8/3/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 77 Male 155 lb 8/5/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/19/2008 67 Male 7/31/2009 France
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 2/1/2007 Female 140 lb 8/25/2009 Consumer United States
Primary
Concomitant
Overdose Other Serious 7/11/2008 56 8/28/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 9/14/2006 61 Female 157 lb 9/3/2009 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 71 Male 9/8/2009 Physician United States
Primary
Secondary
Respiratory Failure Hospitalization 9/4/2009 Male 9/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 11/1/2003 39 Female 9/16/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/4/2009 Male 9/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Suicide Attempt Other Serious 2/1/2007 Female 140 lb 10/14/2009 Consumer United States
Primary
Concomitant
Substance Abuse Death Female 172 lb 11/6/2009 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 6/11/2007 Female 12/1/2009 Lawyer United States
Primary
Secondary
Concomitant
Tremor 1/1/2009 62 Female 203 lb 12/9/2009 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 6/11/2007 64 Female 97 lb 12/22/2009 Lawyer United States
Primary
Secondary
Concomitant
Pain Other Serious 5/25/2007 64 Female 97 lb 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2008 43 Female 1/14/2010 Physician United States
Primary
Secondary
Urinary Tract Infection Other Serious 1/1/2008 Female 137 lb 1/17/2010 Consumer Brazil
Primary
Concomitant
Pain Other Serious 5/25/2007 64 Female 97 lb 1/18/2010 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 43 Female 1/20/2010 Physician United States
Primary
Secondary
Intentional Drug Misuse Other Serious 43 Female 1/20/2010 Physician United States
Primary
Secondary
Renal Failure Hospitalization 48 Female 1/26/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/3/2009 Female 118 lb 1/29/2010 Physician United States
Primary
Concomitant
Ischaemic Cerebral Infarction Life Threatening 6 Male 53 lb 2/5/2010 Other Health Professional Canada
Primary
Concomitant
Lung Disorder Hospitalization 12/31/2009 Male 205 lb 2/5/2010 Belgium
Primary
Concomitant
Respiratory Arrest Death 1/1/2008 43 Female 2/2/2010 Physician United States
Primary
Secondary
Serotonin Syndrome Other Serious 44 Female 2/24/2010 Physician United States
Primary
Secondary
Concomitant
Interacting
Wrong Technique In Drug Usage Process Death 4/22/2007 Male 275 lb 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Narcotic Intoxication Death 3/2/2002 26 Female 163 lb 3/1/2010 Consumer United States
Primary
Secondary
Pain Other Serious 5/25/2007 64 Female 97 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected 11/18/2009 Female 130 lb 3/8/2010 Consumer United States
Primary
Concomitant
Wheezing Other Serious 2/1/2009 54 Female 220 lb 3/11/2010 Consumer United States
Primary
Secondary
Concomitant
Restlessness Other Serious 1/13/2010 53 Female 130 lb 3/23/2010 Physician Canada
Primary
Secondary
Concomitant

Drug Data