Clonazepam combined with Duloxetine Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Serotonin Syndrome Required Intervention 31 Female 12/8/2006 Physician United States
Primary
Secondary
Epilepsy Other Serious 23 Female 8/2/2007 Physician Portugal
Primary
Concomitant
Oedema Peripheral Hospitalization 7/1/2006 Male 240 lb 9/28/2007 Consumer United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 4/13/2007 Female 10/12/2007 Physician Portugal
Primary
Concomitant
Rash Pruritic 10/17/2007 Female 219 lb 12/14/2007 United States
Primary
Concomitant
Depression Hospitalization 12/20/2007 Male 159 lb 1/18/2008 United States
Primary
Concomitant
Drug Ineffective 11/1/2007 Female 190 lb 3/14/2008 United States
Primary
Concomitant
Respiratory Tract Congestion 1/1/2007 Female 170 lb 3/15/2008 United States
Primary
Concomitant
Alanine Aminotransferase Increased 3/25/2008 Female 4/22/2008 Physician Russian Federation
Primary
Concomitant
Alanine Aminotransferase Increased 3/25/2008 Female 4/25/2008 Physician Russian Federation
Primary
Concomitant
Dactylitis Hospitalization 3/22/2008 Female 5/29/2008 Other Health Professional Switzerland
Primary
Concomitant
Visual Field Defect Other Serious 1/1/2002 Female 5/30/2008 United States
Primary
Secondary
Concomitant
Drug Ineffective 11/1/2007 47 Female 190 lb 6/23/2008 United States
Primary
Concomitant
Shoulder Operation Other Serious 6/19/2008 Female 138 lb 6/27/2008 Consumer United States
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 6/19/2008 Female 138 lb 7/11/2008 Consumer United States
Primary
Concomitant
Gait Disturbance Hospitalization 3/22/2008 Female 7/17/2008 Other Health Professional Switzerland
Primary
Concomitant
Gait Disturbance Hospitalization 3/22/2008 Female 7/24/2008 Other Health Professional Switzerland
Primary
Concomitant
Rash Macular 5/1/2008 Female 241 lb 9/12/2008 United States
Primary
Concomitant
Sensory Disturbance 6/30/2008 Female 9/12/2008 United States
Primary
Concomitant
Psoriatic Arthropathy Female 130 lb 9/13/2008 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Female 250 lb 9/13/2008 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2008 Female 10/28/2008 Physician United States
Primary
Concomitant
Muscle Tightness 3/1/2008 Female 222 lb 11/26/2008 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Female 11/26/2008 United States
Primary
Concomitant
Tremor Other Serious 1/1/2002 Female 12/5/2008 United States
Primary
Secondary
Concomitant
Weight Increased 8/19/2008 Male 200 lb 12/12/2008 United States
Primary
Concomitant
Upper Respiratory Tract Infection 6/16/2008 Female 158 lb 12/12/2008 Physician United States
Primary
Concomitant
Contusion 10/1/2008 Female 183 lb 12/12/2008 Other Health Professional United States
Primary
Concomitant
Pain 1/1/2007 Male 12/12/2008 Consumer United States
Primary
Concomitant
Tremor Other Serious 1/1/2002 Female 2/24/2009 United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 57 Female 2/26/2009 United States
Primary
Secondary
Respiratory Arrest Death 37 Male 2/26/2009 Physician United States
Primary
Secondary
Completed Suicide Death 37 Male 3/20/2009 Physician United States
Primary
Secondary
Convulsion Hospitalization 2/28/2009 Female 3/25/2009 Consumer United States
Primary
Secondary
Concomitant
Sensation Of Heaviness 8/28/2008 Female 145 lb 4/2/2009 Physician United States
Primary
Concomitant
Respiratory Arrest Death 39 Female 2/6/2009 United States
Primary
Secondary
Intentional Overdose Death 39 Female Physician United States
Primary
Secondary
Suicide Attempt Hospitalization 5/4/2009 Male 6/2/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 51 Female 300 lb 6/18/2009 United States
Primary
Concomitant
Completed Suicide Death 42 Female 7/1/2009 Physician United States
Primary
Secondary
Completed Suicide Death 57 Female 7/1/2009 Physician United States
Primary
Secondary
Diabetes Mellitus Hospitalization 11/1/2005 32 Female 133 lb 7/24/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 3/25/2003 45 Female 370 lb 8/3/2009 United States
Primary
Concomitant
Alopecia Male 180 lb 8/6/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2004 35 Female 8/6/2009 Consumer United States
Primary
Secondary
Concomitant
Pruritus 42 Female 8/21/2009 Physician United States
Primary
Concomitant
Hyperhidrosis 9/1/2008 Female 8/21/2009 United States
Primary
Concomitant
Flushing 9/5/2008 Female 8/22/2009 United States
Primary
Concomitant
Pruritus Generalised 7/23/2009 Male 185 lb 8/23/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 1/21/2008 Female 137 lb 8/24/2009 Brazil
Primary
Concomitant
Physical Assault Other Serious 8/14/2009 Male 9/1/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 7/14/2007 Male 195 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 7/19/2007 Female 137 lb 9/11/2009 Consumer United States
Primary
Concomitant
Drug Eruption Hospitalization Female 9/24/2009 Physician Brazil
Primary
Secondary
Physical Assault Other Serious 8/14/2009 Male 10/20/2009 Consumer United States
Primary
Concomitant
Physical Assault Other Serious 8/14/2009 Male 11/2/2009 Physician United States
Primary
Concomitant
Death Death 9/15/2009 Male 11/16/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Headache Other Serious 50 Female 11/18/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Drug Abuse Other Serious 50 Female 11/23/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Headache Other Serious 50 Female 11/25/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Procedural Pain Hospitalization 11/1/2007 Female 12/1/2009 Consumer United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2008 51 Female 2/1/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 51 Female 2/1/2010 Physician United States
Primary
Secondary
Obsessive Thoughts 9/11/2008 25 Male 220 lb 9/15/2008 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 42 Female 2/23/2010 Physician United States
Primary
Secondary
Serotonin Syndrome Other Serious 44 Female 2/24/2010 Physician United States
Primary
Secondary
Concomitant
Interacting
Death Death 51 Female 2/26/2010 Other Health Professional United States
Primary
Secondary
Urinary Hesitation 10/12/2008 53 Male 292 lb 11/13/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Death Death 51 Female 3/5/2010 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 42 Female 3/5/2010 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 51 Female 2/26/2010 Other Health Professional Denmark
Primary
Secondary
Unresponsive To Stimuli Other Serious 44 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Serotonin Syndrome Other Serious 44 Female 3/26/2010
Primary
Secondary
Concomitant
Death Death 1/1/2008 42 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Serotonin Syndrome Other Serious 44 Female 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 1/1/2008 51 Female 3/30/2010 Other Health Professional United States
Primary
Secondary
Unresponsive To Stimuli Other Serious 44 Female 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/12/2010 35 Female 176 lb 3/31/2010 Pharmacist United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 44 Female 4/5/2010 Physician United States
Primary
Secondary
Serotonin Syndrome Other Serious 44 Female 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 44 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Urine Odour Abnormal Hospitalization 1/1/2010 58 Female 143 lb 4/5/2010 Consumer United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/2/2010 37 Female 179 lb 4/9/2010 Consumer United States
Primary
Concomitant
Serotonin Syndrome Other Serious 44 Female 4/15/2010 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 44 Female 4/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 66 Female 5/5/2010 Other Health Professional Italy
Primary
Secondary
Unresponsive To Stimuli Other Serious 44 Female 5/10/2010 Consumer United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 66 Female 5/10/2010 Other Health Professional Italy
Primary
Secondary
Mental Status Changes Hospitalization 66 Female 5/10/2010 Other Health Professional Italy
Primary
Secondary
Mental Status Changes Hospitalization 66 Female 5/10/2010 Other Health Professional Italy
Primary
Secondary
Mental Status Changes Hospitalization 66 Female 5/10/2010 Other Health Professional Italy
Primary
Secondary
Mental Status Changes Hospitalization 66 Female 5/10/2010 Other Health Professional Italy
Primary
Secondary
Mental Status Changes Hospitalization 66 Female 5/10/2010 Other Health Professional Italy
Primary
Secondary
Serotonin Syndrome Other Serious 44 Female 5/20/2010 Physician United States
Primary
Secondary
Concomitant
Bronchospasm Other Serious 3/23/2010 52 Male 233 lb 5/27/2010 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Hospitalization 66 Female 5/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Suicide Attempt Other Serious 66 Female 6/2/2010 Other Health Professional Italy
Primary
Secondary
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/21/2008 63 Female 137 lb 7/2/2010 Other Health Professional Brazil
Primary
Concomitant
Tremor 50 Male 6/24/2010 Consumer United States
Primary
Secondary
Interacting
Asthma Other Serious 3/23/2010 52 Male 233 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Bronchospasm Other Serious 3/23/2010 52 Male 233 lb 7/12/2010 Other Health Professional United States
Primary
Concomitant
Asthma Other Serious 3/23/2010 52 Male 233 lb 7/27/2010 Other Health Professional United States
Primary
Concomitant
Haemorrhage Other Serious 4/1/2010 71 Female 146 lb 8/23/2010 Consumer Mexico
Primary
Concomitant
Thrombocytopenia Hospitalization 49 Female 9/20/2010 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 58 Female 9/20/2010 Physician United States
Primary
Concomitant
Somnolence 1/1/2010 34 Female 125 lb 11/6/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 11/4/2009 12/13/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 11/4/2009 12/13/2010 Consumer United States
Primary
Concomitant
Rhinitis Allergic Female 12/14/2010 Physician United States
Primary
Concomitant
Skin Haemorrhage Other Serious 12/29/2009 12/16/2010 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 44 Female 12/7/2010 Physician United States
Primary
Secondary
Concomitant
Rhinitis Allergic Female 1/3/2011 Physician United States
Primary
Concomitant
Completed Suicide Death 70 Female 1/10/2011 Physician United States
Primary
Secondary
Overdose Death 37 Female 1/13/2011 Physician United States
Primary
Secondary
Completed Suicide Death 70 Female 1/13/2011 Physician United States
Primary
Secondary
Sinus Tachycardia Hospitalization 1/1/2010 25 Male 157 lb 1/12/2011 Consumer United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 37 Female 2/2/2011 United States
Primary
Secondary
Secondary Immunodeficiency Hospitalization 11/26/2010 59 Male 170 lb 3/3/2011 Physician United States
Primary
Secondary
Concomitant
Enteritis Hospitalization 11/26/2010 59 Male 170 lb 3/14/2011 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 70 Female 3/30/2011 Physician United States
Primary
Secondary
Intraocular Pressure Increased Other Serious 6/1/2009 28 Female 125 lb 3/22/2011 Consumer United States
Primary
Secondary
Concomitant
Anxiety Other Serious 1/1/2011 38 Female 148 lb 4/1/2011 Consumer United States
Primary
Secondary
Concomitant
Malnutrition Hospitalization Female 4/14/2011 Physician United States
Primary
Concomitant
Rash Maculo-papular Other Serious 8/1/2007 64 Female 160 lb 4/7/2011 Consumer United States
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 8/1/2007 64 Female 160 lb 4/7/2011 Consumer United States
Primary
Secondary
Concomitant
Ear Infection Fungal Hospitalization 9/13/2010 43 Female 190 lb 4/28/2011 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization Female 5/19/2011 Consumer South Africa
Primary
Concomitant
Abdominal Pain Other Serious 4/18/2011 30 Female 125 lb 5/27/2011 Consumer United States
Primary
Concomitant
Road Traffic Accident Death 11/27/2006 53 Male 5/24/2011 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/2/2011 32 Male 51 lb 7/1/2011 United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 49 Female 7/11/2011 Consumer Japan
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 1/1/2007 37 Male 7/12/2011 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 51 Female 7/18/2011 Physician United States
Primary
Secondary
Suicidal Ideation Death 1/1/2008 42 Female 7/21/2011 Physician United States
Primary
Secondary
Hypothyroidism Other Serious 1/1/2007 42 Male 9/22/2011 Consumer United States
Primary
Concomitant
Hypotension Other Serious 7/5/2011 60 Female 10/11/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Liver Injury Other Serious 65 Female 10/26/2011 Physician Korea, Republic Of
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2007 49 Female 185 lb 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious 1/1/2007 49 Female 185 lb 11/1/2011 United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 1/1/2007 49 Female 185 lb 11/2/2011 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 6/1/2009 28 Female 125 lb 11/21/2011 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Death 56 Female 12/14/2011 Other Health Professional United States
Primary
Secondary
Tremor Other Serious 6/1/2009 28 Female 125 lb 12/5/2011 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 37 Female 12/19/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 37 Female 12/19/2011 Other Health Professional United States
Primary
Secondary
Immune System Disorder Hospitalization 1/1/2007 49 Female 185 lb 12/21/2011 United States
Primary
Secondary
Concomitant

Drug Data