Clonazepam combined with Depakote

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 11/7/2005 34 Male 1/16/2006 France
Primary
Secondary
Muscle Tightness 6/1/2005 Male 1/27/2006 Consumer United States
Primary
Concomitant
Vomiting 30 Female 192 lb 1/27/2006 Consumer United States
Primary
Secondary
Middle Insomnia 9/9/2005 52 Male 230 lb 1/5/2006 Consumer United States
Primary
Secondary
Concomitant
Trismus Other Serious 1/5/2006 Male 176 lb 2/2/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 11/7/2005 34 Male 2/15/2006 Consumer France
Primary
Secondary
Respiratory Arrest Death 40 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Viral Infection Hospitalization 11/27/2005 14 Female 2/24/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/19/2005 38 Male 185 lb 1/20/2006 United States
Primary
Concomitant
Insomnia 49 Female 2/28/2006 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 2/11/2006 65 Female 359 lb 2/28/2006 Physician United States
Primary
Concomitant
Missed Labour Other Serious 6/23/2005 31 Female 3/14/2006 Physician Poland
Primary
Concomitant
Weight Decreased 1/1/2005 31 Male 1/20/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/2/2001 44 Female 201 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 44 Female 201 lb 3/23/2006 Physician United States
Primary
Concomitant
Diabetic Ketoacidosis Other Serious 4/22/2005 26 Male 257 lb 6/27/2005 Physician United States
Primary
Concomitant
Hallucination, Auditory Hospitalization 3/14/2006 Male 3/28/2006 Physician United States
Primary
Concomitant
Rash Other Serious 3/25/2006 Male 3/28/2006 Pharmacist United States
Primary
Concomitant
Pseudomonas Infection Life Threatening 8/8/2005 45 Male 4/6/2006 Other Health Professional France
Primary
Secondary
Somnolence Other Serious 5/28/1999 44 Male 220 lb 2/21/2006 Lawyer United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 2/2/2006 56 Female 167 lb 4/12/2006 Pharmacist United States
Primary
Concomitant
Headache Hospitalization 4/9/2006 23 Male 4/24/2006 Other Health Professional France
Primary
Concomitant
Thrombosis Hospitalization 8/29/2001 58 Female 130 lb 5/8/2006 Lawyer United States
Primary
Concomitant
Pyrexia Hospitalization 2/28/2006 61 Male 5/12/2006 Other Health Professional France
Primary
Concomitant
Interacting
Parkinsonism Other Serious 5/1/2006 67 Female 5/22/2006 Physician France
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 1/1/1995 31 Female 3/21/2005 United States
Primary
Secondary
Concomitant
Insomnia 1/1/2005 59 Female 130 lb 4/3/2006 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 5/18/2006 35 Male 177 lb 5/31/2006 Pharmacist United States
Primary
Concomitant
Normochromic Normocytic Anaemia Hospitalization 4/3/2006 Female 6/5/2006 Other Health Professional France
Primary
Concomitant
Pyrexia Hospitalization 1/1/2006 18 Female 121 lb 6/7/2006 Physician Brazil
Primary
Concomitant
Staphylococcal Infection Life Threatening 2/20/2005 49 Male 6/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2006 18 Female 121 lb 6/22/2006 Physician Brazil
Primary
Concomitant
Wheezing Other Serious 5/27/2006 42 Male 154 lb 6/21/2006 Consumer Brazil
Primary
Concomitant
Suicide Attempt Hospitalization 6/11/2006 36 Male 7/14/2006 Consumer United States
Primary
Secondary
Suicide Attempt Hospitalization 6/11/2006 Male 229 lb 7/28/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 19 Male 145 lb 8/3/2006 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 19 Male 145 lb 8/3/2006 United States
Primary
Concomitant
Death Death 8/7/2006 Physician United States
Primary
Concomitant
Death Death Female 8/10/2006 Physician United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 5/10/2006 52 Female 155 lb 8/18/2006 Physician United States
Primary
Concomitant
Hypoaesthesia Other Serious 4/17/2006 51 Female 220 lb 7/19/2006 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 8/1/2006 84 Female 8/30/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2006 46 Male 9/15/2006 Physician Brazil
Primary
Secondary
Concomitant
Prothrombin Time Shortened Hospitalization 6/27/2006 32 Male 9/18/2006 Consumer France
Primary
Concomitant
Injection Site Irritation 6/26/2006 56 Female 159 lb 8/4/2006 Pharmacist United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 3/10/2006 53 Female 10/27/2006 Consumer France
Primary
Secondary
Cytolytic Hepatitis Hospitalization 3/10/2006 53 Female 10/23/2006 Other Health Professional France
Primary
Secondary
Gamma-glutamyltransferase Increased Hospitalization 3/10/2006 53 Female 10/31/2006 Consumer France
Primary
Secondary
Vision Blurred Required Intervention 1/1/2005 64 Female 187 lb 1/1/2005 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/18/2006 50 Male 11/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 3/10/2006 53 Female 11/17/2006 Consumer France
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 11/7/2006 52 Female 175 lb 11/22/2006 United States
Primary
Concomitant
Memory Impairment Other Serious 11/1/2006 49 Female 12/11/2006 Consumer United States
Primary
Concomitant
Skin Odour Abnormal 30 Male 12/20/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2002 Female 12/21/2006 Consumer United States
Primary
Secondary
Concomitant
Interacting
Gamma-glutamyltransferase Increased Hospitalization 3/10/2006 53 Female 12/28/2006 Consumer France
Primary
Secondary
Concomitant
Memory Impairment Other Serious 11/1/2006 49 Female 12/21/2006 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 2/15/2002 Male 12/29/2006 Lawyer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 11/1/2006 49 Female 1/4/2007 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 8/8/2006 8 Female 45 lb 8/14/2006 Consumer United States
Primary
Concomitant
Hyperglycaemia Hospitalization 1/1/2002 34 Female 191 lb 1/16/2007 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 1/5/2006 48 Male 176 lb 11/28/2006 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 4/1/2006 Male 5/12/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/13/2006 5 Male 35 lb 1/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 1/1/2007 52 Female 223 lb 1/26/2007 Other Health Professional United States
Primary
Concomitant
Mouth Ulceration 11/3/2006 49 Male 3/1/2007 Consumer United States
Primary
Concomitant
Tooth Fracture Other Serious 4/1/2000 52 Female 136 lb 3/16/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2006 Female 108 lb 3/23/2007 Consumer United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Required Intervention 4/1/2003 46 Female 8/21/2004 Physician United States
Primary
Concomitant
Hyperglycaemia Hospitalization 1/1/2002 34 Female 191 lb 3/27/2007 Consumer United States
Primary
Concomitant
Petit Mal Epilepsy Hospitalization 1/28/2007 Male 151 lb 4/9/2007 Consumer United States
Primary
Concomitant
Multiple Sclerosis Other Serious 3/1/2007 48 Female 154 lb 4/9/2007 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 1/20/2007 57 Male 141 lb 3/2/2007 Pharmacist United States
Primary
Concomitant
Suicide Attempt Other Serious 2/15/2002 Male 5/16/2007 Lawyer United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 12/1/2001 49 Male 161 lb 5/18/2007 Consumer United States
Primary
Concomitant
Multiple Sclerosis Other Serious 3/1/2007 48 Female 154 lb 5/23/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious Female 3/28/2007 United States
Primary
Secondary
Concomitant
Mania 1/1/2006 22 Male 197 lb 3/13/2007 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 7/5/2005 Female 93 lb 6/13/2007 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1999 47 210 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2001 38 Female 360 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 45 Male 136 lb 6/20/2007 Physician United States
Primary
Concomitant
Drug Interaction Hospitalization Male 6/27/2007 Pharmacist United States
Primary
Concomitant
Interacting
Therapeutic Agent Toxicity Other Serious 7/5/2005 Female 93 lb 7/10/2007 Lawyer United States
Primary
Secondary
Concomitant
Angioedema Other Serious 7/17/2007 47 Female 8/3/2007 Physician France
Primary
Concomitant
Somnolence Other Serious 57 Female 132 lb 8/3/2007 Consumer Brazil
Primary
Concomitant
Constipation 3/1/2007 52 Male 120 lb 7/10/2007 Consumer United States
Primary
Concomitant
Overdose Hospitalization 6/24/2007 26 Male 8/31/2007 Physician France
Primary
Concomitant
Drug Interaction Hospitalization Male 37 lb 9/4/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Sudden Death Death 7/29/2007 38 Male 9/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 7/24/2007 Male 9/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Paraesthesia Other Serious 5/1/2007 63 Female 176 lb 9/7/2007 Consumer Brazil
Primary
Concomitant
Pancreatitis Hospitalization 3/16/2002 33 Male 175 lb 9/17/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased 1/1/2004 64 Male 255 lb 9/17/2007 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 7/25/2007 49 Female 106 lb 8/21/2007 Pharmacist United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2006 Male 127 lb 9/18/2007 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 36 Female 135 lb 9/13/2007 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization Male 37 lb 10/12/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Neutropenia Other Serious 12/1/2006 22 Male 9/28/2007 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint 9/7/2006 30 Female 10/25/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2006 Female 11/2/2007 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2005 Female 123 lb 11/13/2007 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization Female 11/27/2007 Physician United States
Primary
Secondary
Concomitant
Asthenopia 8/14/2007 54 Male 11/16/2007 United States
Primary
Concomitant
Swelling Face Other Serious 6/1/2004 48 Female 179 lb 11/1/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 4/1/2000 52 Female 136 lb 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting 6/1/2006 18 Male 130 lb 6/5/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Life Threatening 9/1/2007 Male 12/20/2007 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 7/15/2007 Male 12/20/2007 Physician United States
Primary
Secondary
Concomitant
Convulsion Other Serious 6/1/2007 26 Female 12/18/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 6/7/2007 26 Male 180 lb 6/7/2007 Pharmacist United States
Primary
Concomitant
Weight Increased 5/8/2007 21 Male 163 lb 5/8/2007 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 9/1/2001 47 Male 236 lb 12/27/2007 Consumer United States
Primary
Concomitant
Overdose Death 11/28/2007 24 Female 12/28/2007 Physician United States
Primary
Concomitant
Overdose Death 11/28/2007 24 Female 1/3/2008 Physician United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 7/23/2007 17 Male 77 lb 11/25/2007 Physician United States
Primary
Concomitant
Tachycardia Paroxysmal Other Serious 10/1/2004 52 Female 175 lb 1/18/2008 Lawyer United States
Primary
Concomitant
Syncope Other Serious 68 Female 172 lb 1/24/2008 Consumer Brazil
Primary
Secondary
Concomitant
Vision Blurred Other Serious 4/26/2000 Male 301 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Required Intervention 12/1/2007 59 Male 1/28/2008 Physician United States
Primary
Concomitant
Neonatal Respiratory Distress Syndrome Hospitalization 2/22/2007 Male 2/1/2008 Other Health Professional France
Primary
Secondary
Retrognathia Hospitalization 2/22/2007 Male 2/1/2008 Other Health Professional France
Primary
Secondary
Visual Disturbance Other Serious 12/1/2007 Female 140 lb 2/5/2008 United States
Primary
Secondary
Concomitant
Tremor Life Threatening 7/15/2007 Male 2/15/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/1/2007 Male 2/15/2008 Physician United States
Primary
Concomitant
Suicide Attempt Hospitalization 2/1/2007 Female 2/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pseudodementia Hospitalization 4/4/2007 Male 3/3/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Parkinsonian Rest Tremor Other Serious 7/16/1990 64 Male 165 lb 3/4/2008 Physician Brazil
Primary
Secondary
Concomitant
Pseudodementia Hospitalization 4/4/2007 77 Male 2/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Arthralgia 9/28/2007 40 Female 2/15/2008 United States
Primary
Concomitant
Parkinsonian Rest Tremor Other Serious 7/16/1990 64 Male 165 lb 3/7/2008 Physician Brazil
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 7/16/1990 64 Male 165 lb 3/11/2008 Physician Brazil
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 12/31/2007 Female 3/13/2008 Other Health Professional France
Primary
Secondary
Concomitant
Off Label Use 2/25/2008 29 Male 3/5/2008 Pharmacist United States
Primary
Concomitant
Neonatal Respiratory Distress Syndrome Hospitalization 2/22/2007 Male 3/17/2008 Other Health Professional France
Primary
Secondary
Retrognathia Hospitalization 2/22/2007 Male 3/19/2008 Other Health Professional France
Primary
Secondary
Type 1 Diabetes Mellitus Life Threatening 1/2/2008 43 Female 3/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Sedation Life Threatening 1/1/2008 43 Female 3/20/2008 Pharmacist France
Primary
Secondary
Concomitant
Intentional Drug Misuse 2/25/2008 29 Male 3/20/2008 Pharmacist United States
Primary
Concomitant
Tongue Injury 3/26/2007 Female 170 lb 4/11/2008 Physician United States
Primary
Concomitant
Vomiting 3/31/2007 37 Male 220 lb 4/11/2008 Consumer United States
Primary
Concomitant
Weight Decreased 5/1/2007 14 Female 100 lb 4/11/2008 Consumer United States
Primary
Concomitant
Vision Blurred 7/1/2007 Female 182 lb 4/11/2008 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 12/1/2005 Male 231 lb 4/11/2008 Physician United States
Primary
Concomitant
Somnolence 9/21/2007 Female 145 lb 4/11/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 12/13/2007 Female 147 lb 4/11/2008 Consumer United States
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 2/3/2004 Female 150 lb 4/11/2008 Consumer United States
Primary
Concomitant
Weight Increased 64 Male 4/11/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/22/2008 30 Male 4/16/2008 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Life Threatening 35 Female 4/17/2008 Physician Brazil
Primary
Secondary
Concomitant

Drug Data