Clonazepam combined with Cyclobenzaprine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Intentional Overdose Life Threatening 44 Male 3/24/2006 Pharmacist United States
Primary
Secondary
Unresponsive To Stimuli Death 1/1/2008 33 Male 6/4/2008 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 33 Male 7/4/2008 Other Health Professional United States
Primary
Secondary
Cerebrovascular Accident Death 1/1/2007 58 Female 11/7/2008 Physician United States
Primary
Concomitant
Respiratory Arrest Death 36 Female 1/19/2009 Physician United States
Primary
Secondary
Dysuria 10/1/2008 53 Male 292 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Pruritus Male 2/24/2009 United States
Primary
Concomitant
Respiratory Arrest Death 36 Female 2/27/2009 Physician United States
Primary
Secondary
Completed Suicide Death 36 Female 3/20/2009 Physician United States
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 7/1/2003 29 Female 4/3/2009 United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 4/15/2003 53 Female 284 lb 4/3/2009 United States
Primary
Concomitant
Erythema Nodosum Other Serious 1/1/2007 Female 4/6/2009 Physician United States
Primary
Concomitant
Somnolence Life Threatening 11/10/2008 52 Male 234 lb 3/16/2009 Other Health Professional United States
Primary
Concomitant
Violence-related Symptom Other Serious 1/1/2008 Female 200 lb 4/10/2009 Consumer United States
Primary
Concomitant
Peptic Ulcer Hospitalization 1/1/2008 62 Female 195 lb 4/7/2009 Physician United States
Primary
Secondary
Concomitant
Skin Laceration Other Serious 1/1/2003 40 Female 150 lb 4/14/2009 United States
Primary
Concomitant
Wound Hospitalization 2/10/2002 40 Male 194 lb 5/20/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/1998 33 Male 231 lb 6/3/2009 United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/2000 48 Female 182 lb 6/25/2009 United States
Primary
Concomitant
Product Quality Issue Death 11/15/2007 Female 150 lb 7/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/1999 40 Female 134 lb 7/16/2009 United States
Primary
Concomitant
Hypoglycaemia Other Serious 4/7/2004 54 Male 251 lb 7/17/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/21/2005 32 Female 204 lb 7/17/2009 United States
Primary
Concomitant
Mitral Valve Incompetence Other Serious 1/1/2007 Male 194 lb 8/21/2009 Brazil
Primary
Concomitant
Flushing 9/5/2008 Female 8/22/2009 United States
Primary
Concomitant
Suicide Attempt Other Serious 2/1/2007 Female 140 lb 8/25/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 6/1/2007 68 Male 9/21/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/14/2003 33 Female 300 lb 9/23/2009 United States
Primary
Concomitant
Overdose Other Serious 4/1/2007 51 Female 263 lb 9/23/2009 United States
Primary
Concomitant
Urinary Tract Infection 5/25/2001 35 Female 100 lb 9/23/2009 United States
Primary
Concomitant
Diabetic Coma Other Serious 4/27/2004 46 Female 153 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2005 34 Female 249 lb 9/23/2009 United States
Primary
Concomitant
Somnambulism Other Serious 3/12/2003 61 Female 155 lb 9/23/2009 United States
Primary
Concomitant
Torticollis 10/31/2003 52 Female 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 6/24/2002 46 Female 180 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/1/2003 45 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus 1/1/2005 38 Female 9/23/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus 9/1/2006 28 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 45 11/10/2009 Other Health Professional United States
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 11/30/2009 Consumer United States
Primary
Concomitant
Confusional State Other Serious 11/16/2009 24 Male 177 lb 12/8/2009 Pharmacist United States
Primary
Secondary
Vomiting Other Serious 3/30/2004 51 Male 390 lb 1/13/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 1/20/2010 Other Health Professional United States
Primary
Concomitant
Drug Toxicity Death 42 Female 1/22/2010 Physician United States
Primary
Secondary
Renal Failure Hospitalization 48 Female 1/26/2010 Other Health Professional United States
Primary
Concomitant
Poisoning Death 42 Female 1/18/2010 Physician United States
Primary
Secondary
Muscular Weakness 7/22/2009 Male 200 lb 1/29/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2001 48 Male 390 lb 2/3/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 2/19/2010 Other Health Professional United States
Primary
Concomitant
Product Quality Issue Required Intervention 4/18/2008 59 Female 125 lb 2/8/2010 United States
Primary
Concomitant
Completed Suicide Death 42 Female 2/23/2010 Physician United States
Primary
Secondary
Drug Toxicity Death Female 2/27/2010 Physician United States
Primary
Secondary
Dysuria 10/1/2008 53 Male 292 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/1/2001 48 Male 390 lb 3/2/2010 United States
Primary
Concomitant
Tremor Hospitalization 2/1/2010 Male 278 lb 3/4/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/30/2004 56 Female 170 lb 3/12/2010 United States
Primary
Concomitant
Mobility Decreased Other Serious 1/1/2009 Female 3/19/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 10/16/2003 Female 276 lb 3/24/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 3/26/2010 Other Health Professional United States
Primary
Concomitant
Angioedema Hospitalization 5/1/2009 Female 195 lb 3/29/2010 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Death 11/15/2007 Female 150 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/13/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 57 Female 276 lb 4/14/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 57 Female 276 lb 4/19/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/22/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/3/2010 United States
Primary
Concomitant
Sedation Death 11/15/2007 50 Female 150 lb 5/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/7/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/12/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2001 48 Male 390 lb 5/14/2010 United States
Primary
Concomitant
Angioedema Hospitalization 5/1/2009 34 Female 195 lb 5/14/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/21/2010 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/1998 33 Male 231 lb 5/31/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/2/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2002 43 Male 6/1/2010 Physician United States
Primary
Concomitant
Tremor Hospitalization 2/1/2010 54 Male 278 lb 6/11/2010 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2010 58 Female 215 lb 6/11/2010 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 10/9/2008 55 Female 237 lb 6/10/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/15/2010 United States
Primary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 176 lb 6/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Disorder Other Serious 4/22/2010 66 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Type 2 Diabetes Mellitus Other Serious 1/1/2002 48 Female 170 lb 7/2/2010 United States
Primary
Concomitant
Sedation Death 11/15/2007 50 Female 150 lb 7/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Procedural Site Reaction Other Serious Female 143 lb 7/8/2010 Consumer Brazil
Primary
Concomitant
Vomiting Other Serious 1/1/2006 44 Female 180 lb 7/8/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 52 Female 132 lb 7/9/2010 Consumer Brazil
Primary
Secondary
Concomitant
Paraesthesia Other Serious 1/1/2010 58 Female 215 lb 7/12/2010 Consumer United States
Primary
Secondary
Concomitant
Toothache 1/1/2007 55 Female 100 lb 7/12/2010 Other Health Professional United States
Primary
Concomitant
Tobacco User Other Serious 1/1/2007 58 Female 224 lb 7/13/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 56 Male 125 lb 7/14/2010 Other Health Professional United States
Primary
Concomitant
Headache 7/9/2007 63 Male 118 lb 7/14/2010 Consumer United States
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/21/2010 Other Health Professional United States
Primary
Concomitant
Overdose Other Serious 70 Female 7/29/2010 Other Health Professional United States
Primary
Concomitant
Sedation Death 11/15/2007 50 Female 150 lb 7/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 7/11/2008 35 Female 152 lb 7/30/2010 Consumer United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/29/2006 25 Female 229 lb 8/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Sciatic Nerve Neuropathy 5/1/2009 70 Male 222 lb 8/4/2010 Consumer United States
Primary
Concomitant
Tremor Hospitalization 6/11/2010 38 Female 123 lb 8/13/2010 Physician United States
Primary
Concomitant
Self Injurious Behaviour Other Serious 6/1/2009 46 Female 294 lb 8/24/2010 Other Health Professional United States
Primary
Concomitant
Paraesthesia 3/10/2010 59 Male 192 lb 8/29/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 25 Female 261 lb 9/3/2010 United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 4/30/2010 32 Female 9/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/29/2010 65 Female 250 lb 9/2/2010 Consumer United States
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 9/8/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 9/9/2010 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Other Serious 2/1/2007 35 Female 140 lb 9/16/2010 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 4/18/2003 45 Male 286 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 45 Female 155 lb 9/20/2010 United States
Primary
Concomitant
Pancreatitis Acute Other Serious 2/2/2006 37 Male 235 lb 9/20/2010 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 9/6/2000 58 Female 241 lb 9/20/2010 United States
Primary
Concomitant
Suicidal Ideation Other Serious 10/1/2009 52 Female 250 lb 9/22/2010 Physician United States
Primary
Secondary
Concomitant
Vertigo Other Serious Female 9/21/2010 Consumer United States
Primary
Secondary
Concomitant
Chest Discomfort Hospitalization 9/12/2010 53 Female 170 lb 9/23/2010 Other Health Professional Canada
Primary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 9/30/2010 Consumer United States
Primary
Concomitant
Tremor Hospitalization 1/1/2007 38 Female 123 lb 10/21/2010 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 10/1/2009 52 Female 250 lb 10/22/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 9/23/2010 77 Male 434 lb 10/25/2010 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 55 Female 10/27/2010 Physician United States
Primary
Secondary
Septic Shock Hospitalization 9/23/2010 77 Male 434 lb 10/27/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 10/27/2010 Consumer United States
Primary
Concomitant
Palpitations 53 Female 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/29/2010 65 Female 250 lb 10/21/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 57 Female 200 lb 11/12/2010 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 11/15/2010 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 11/19/2010 Consumer United States
Primary
Concomitant
Nephrosclerosis Required Intervention 4/18/2008 59 Female 125 lb 11/23/2010 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Other Serious 2/1/2007 35 Female 140 lb 10/14/2009 Consumer United States
Primary
Concomitant
Tremor Other Serious 6/27/2010 71 Female 12/28/2010 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Death 70 Female 1/4/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 1/1/2009 70 Female 1/7/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 1/1/2009 22 Male 1/10/2011 Physician United States
Primary
Secondary
Completed Suicide Death 22 Male 1/11/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 25 Female 1/11/2011 Physician United States
Primary
Secondary
Memory Impairment Other Serious 10/1/2009 52 Female 250 lb 1/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 70 Female 1/13/2011 Physician United States
Primary
Secondary
Completed Suicide Death 70 Female 1/13/2011
Primary
Secondary
Completed Suicide Death 22 Male 1/19/2011 Physician United States
Primary
Secondary
Completed Suicide Death 25 Female 1/19/2011 Physician United States
Primary
Secondary
Completed Suicide Death 70 Female 1/19/2011 Physician United States
Primary
Secondary
Sinusitis Hospitalization 6/15/2007 43 Female 209 lb 11/4/2010 Lawyer United States
Primary
Concomitant
Insomnia Other Serious 10/1/2009 52 Female 250 lb 1/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 22 Male 1/28/2011 Other Health Professional United States
Primary
Secondary
Dizziness Hospitalization 8/12/2008 36 Female 161 lb 1/28/2011 Physician United States
Primary
Secondary
Concomitant
Injection Site Pain 10/24/2010 57 Male 294 lb 1/30/2011 Consumer United States
Primary
Concomitant
Medication Residue 1/1/2010 35 Female 1/31/2011 Consumer United States
Primary
Concomitant

Drug Data