Clonazepam combined with Clozapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rhabdomyolysis Hospitalization 1/1/2005 36 Male 1/9/2006 France
Primary
Secondary
Weight Increased Other Serious 11/3/2005 36 Male 197 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Myalgia Hospitalization 11/3/2005 Male 2/6/2006 France
Primary
Secondary
Concomitant
Myalgia Hospitalization 11/3/2005 36 Male 2/16/2006 Pharmacist France
Primary
Secondary
Concomitant
Menorrhagia Hospitalization 10/2/2005 47 Female 2/15/2006 United States
Primary
Concomitant
Pyrexia Hospitalization 12/15/2005 56 Male 3/3/2006 France
Primary
Concomitant
Dementia Alzheimer's Type Death 1/10/2006 83 Female 2/27/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2006 45 Female 170 lb 3/7/2006 Other Health Professional United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 8/9/2005 54 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 1/30/2006 68 Female 3/14/2006 United States
Primary
Concomitant
Diabetic Ketoacidosis Other Serious 4/22/2005 26 Male 257 lb 6/27/2005 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/18/2005 36 Female 126 lb 12/14/2005 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2005 62 Female 12/14/2005 Physician United States
Primary
Concomitant
Suicidal Ideation Hospitalization 4/1/2005 42 Male 6/8/2005 Physician United States
Primary
Concomitant
Unevaluable Event Death 8/10/2005 49 Male 12/14/2005 Pharmacist United States
Primary
Concomitant
Drug Ineffective Hospitalization 7/3/2005 51 Male 12/14/2005 Physician United States
Primary
Concomitant
Unevaluable Event Death 6/27/2005 62 Female 12/14/2005 Physician United States
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 5/16/2005 49 Female 12/14/2005 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/2/2005 33 Female 192 lb 2/2/2005 Pharmacist United States
Primary
Concomitant
Lung Neoplasm Malignant Death 1/30/2006 68 Female 4/7/2006 United States
Primary
Concomitant
Disease Progression Death 1/10/2006 83 Female 4/17/2006 United States
Primary
Concomitant
Sarcoma Other Serious 9/1/2005 33 Male 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Lung Cancer Metastatic Death 3/19/2006 42 Male 5/1/2006 United States
Primary
Concomitant
Death Death 4/15/2006 52 Male 6/6/2006 United States
Primary
Concomitant
Mental Disorder Required Intervention 1/26/2006 45 Female 6/14/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/20/2005 26 Female 3/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/28/2005 21 Male 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/23/2006 27 Female 4/11/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/25/2006 64 Female 4/11/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/23/2006 42 Female 6/12/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/12/2005 45 Female 1/30/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/13/2005 36 Male 1/27/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Life Threatening 10/5/2005 51 Female 1/25/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/9/2005 29 Male 155 lb 6/20/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/1/2005 61 Male 173 lb 5/12/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 10/17/2005 46 Male 1/27/2006 Consumer United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 8/30/2005 64 Male 177 lb 2/8/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/26/2005 36 Male 259 lb 1/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/28/2005 32 Male 1/25/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 9/19/2005 44 Female 1/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/4/2005 42 Male 5/24/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/7/2005 28 Female 5/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/14/2005 53 Male 3/29/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 10/24/2005 51 Male 1/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/14/2005 29 Male 150 lb 3/22/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/7/2005 46 Male 141 lb 2/14/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/8/2005 54 Male 2/7/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 11/8/2005 47 Male 2/6/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/26/2005 41 Female 2/6/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/8/2005 59 Female 3/22/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/12/2006 56 Female 140 lb 6/21/2006 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 10/1/2005 29 Male 2/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 3/10/2006 31 Male 300 lb 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/25/2005 25 Male 5/31/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/13/2005 46 Male 5/31/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 8/17/2005 33 Male 1/5/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/1/2005 35 Male 190 lb 1/6/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/12/2005 49 Male 220 lb 1/16/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/19/2005 49 Female 178 lb 1/16/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1999 27 Female 8/17/2006 Other Health Professional New Zealand
Primary
Secondary
Leukopenia Required Intervention 11/10/2005 50 Female 3/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/10/2006 52 Female 5/22/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/16/2005 30 Female 2/24/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 11/2/2005 43 Male 196 lb 6/16/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 40 Female 3/21/2006 United States
Primary
Concomitant
Weight Increased Required Intervention 8/31/2005 41 Female 1/11/2006 United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 9/13/2005 58 Male 1/9/2006 Consumer United States
Primary
Concomitant
Death Death 7/4/2006 36 Male 8/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 7/27/2006 43 Female 9/28/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 7/27/2006 43 Female 10/10/2006 Other Health Professional United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 7/26/2006 32 Male 10/11/2006 Other Health Professional Switzerland
Primary
Concomitant
Intestinal Obstruction Death 10/9/2006 22 Male 10/18/2006 United States
Primary
Concomitant
Schizoaffective Disorder Death 7/14/2006 44 Male 300 lb 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Death Death 9/1/2006 50 Male 11/6/2006 Other Health Professional United States
Primary
Concomitant
Psychotic Disorder Required Intervention 35 Male 11/7/2006 United States
Primary
Concomitant
Intestinal Obstruction Death 10/5/2006 22 Male 11/14/2006 United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 7/14/2006 45 Male 300 lb 11/22/2006 Physician United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 12/7/2006 Male 12/28/2006 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 7/1/2006 Male 300 lb 1/9/2007 Physician United States
Primary
Concomitant
Interacting
Ventricular Fibrillation Death 1/1/2006 44 Male 300 lb 1/11/2007 Physician United States
Primary
Secondary
Concomitant
Polycystic Ovaries Hospitalization 3/1/2006 27 Female 2/8/2007 Physician Philippines
Primary
Concomitant
Restlessness Hospitalization 17 Male 2/13/2007 Thailand
Primary
Secondary
Concomitant
Vomiting Hospitalization 62 Male 2/22/2007 Other Health Professional Hungary
Primary
Concomitant
Vomiting Other Serious 2/21/2007 31 3/2/2007 Physician Peru
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 11/24/2006 54 Male 2/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/21/2007 31 3/9/2007 Physician Peru
Primary
Concomitant
Vomiting Other Serious 2/21/2007 31 3/18/2007 Physician Peru
Primary
Concomitant
Vomiting Other Serious 2/21/2007 31 3/23/2007 Physician Peru
Primary
Concomitant
Ultrasound Liver Abnormal Hospitalization 9/19/2005 Male 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Stupor Hospitalization 38 Male 5/11/2007 Other Health Professional United States
Primary
Concomitant
Stupor Hospitalization 38 Male 5/11/2007 Other Health Professional United States
Primary
Concomitant
Cardiac Tamponade Death 6/1/2007 Female 225 lb 6/15/2007 Physician United States
Primary
Concomitant
Neutrophil Count Increased Other Serious 5/8/2007 33 Male 164 lb 7/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 7/24/2007 Male 9/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Hospitalization 31 Male 11/9/2007 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 62 Male 11/13/2007 Physician Hungary
Primary
Concomitant
Vomiting Hospitalization 7/25/2001 Male 157 lb 11/20/2007 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 55 Male 12/10/2007 Physician United States
Primary
Concomitant
Weight Increased Life Threatening 6/8/2007 24 Female 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 6/4/2007 24 Female 12/14/2007 Physician United States
Primary
Secondary
Concomitant
Tremor Required Intervention 5/18/2007 28 Male 170 lb 5/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Intentional Self-injury Other Serious 33 Female 2/29/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 13 Female 3/10/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 13 Female 3/10/2008 Other Health Professional United States
Primary
Concomitant
Rash Generalised Other Serious 20 Male 3/9/2008 Consumer
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2000 15 Male 4/7/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 20 Male 4/9/2008 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/19/2008 44 Male 4/21/2008 Germany
Primary
Secondary
Concomitant
Surgery Other Serious 3/1/2001 Female 5/7/2008 Other Health Professional
Primary
Secondary
Ileus Hospitalization 3/8/2004 Female 5/8/2008 Physician Italy
Primary
Secondary
Ileus Hospitalization 3/8/2004 Female 5/9/2008 Other Health Professional Denmark
Primary
Secondary
Volvulus Other Serious 3/8/2004 Female 5/22/2008 Physician Italy
Primary
Secondary
Volvulus Other Serious 3/8/2004 Female 5/30/2008 Physician Italy
Primary
Concomitant
Completed Suicide Death 24 6/9/2008 Other Health Professional United States
Primary
Secondary
Respiratory Depression Death 4/6/2008 43 Male 6/16/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/29/2008 Norway
Primary
Concomitant
Retinal Exudates Other Serious 6/9/2008 42 Female 8/18/2008 Other Health Professional United States
Primary
Concomitant
Telangiectasia Other Serious 6/9/2008 42 Female 8/27/2008 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2008 42 Female 8/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/19/2008 44 Male 9/5/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/1/2007 22 Male 9/24/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 10/2/2008 Female 10/21/2008 Consumer Colombia
Primary
Concomitant
Tonsillitis Hospitalization 3/28/2008 36 Male 11/4/2008 France
Primary
Secondary
Tonsillitis Hospitalization 3/28/2008 36 Male 11/12/2008 France
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 1/1/2008 42 Female 11/19/2008 Physician United States
Primary
Secondary
Concomitant
Testis Cancer Other Serious 1/1/2000 Male 187 lb 12/8/2008 Consumer Argentina
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 45 Male 12/8/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Viral Myocarditis Hospitalization 3/3/2008 21 Female 12/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Liver Disorder Other Serious 58 Male 12/26/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 58 Male 12/29/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2000 Male 187 lb 1/6/2009 Consumer Argentina
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 12/1/2007 Female 1/8/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Sudden Death Death 12/1/2007 74 Female 1/9/2009 Consumer Italy
Primary
Secondary
Concomitant
Retinal Exudates Other Serious 6/9/2008 42 Female 1/9/2009 Physician United States
Primary
Concomitant
Hepatic Function Abnormal Other Serious 58 Male 1/12/2009 Physician Netherlands
Primary
Secondary
Concomitant
Infection Hospitalization 58 Male 1/23/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Drug Level Increased Hospitalization 58 Male 1/28/2009 Consumer Netherlands
Primary
Secondary
Concomitant
Urinary Tract Infection Required Intervention 58 Male 2/11/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pleurothotonus Disability 67 Male 2/5/2009 Physician Argentina
Primary
Secondary
Concomitant
Death Death 12/8/2008 60 Male 179 lb 2/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Mania Other Serious 22 Male 2/27/2009 Consumer United States
Primary
Secondary
Neutropenia Other Serious 45 Male 3/16/2009 Other Health Professional Canada
Primary
Secondary
Liver Disorder Other Serious 58 Male 3/27/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hypoxia Hospitalization 1/30/2009 Male 4/1/2009 Physician France
Primary
Secondary
Restless Legs Syndrome Other Serious 36 Female 3/30/2009 Physician Korea, Republic Of
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/18/2009 Male 158 lb 4/24/2009 Physician United States
Primary
Concomitant
Sudden Death Other Serious 1/1/2007 33 Male 6/12/2009 Physician Canada
Primary
Concomitant
Drug Interaction Hospitalization 58 Male 6/23/2009 Netherlands
Primary
Concomitant
Cerebral Hypoperfusion Other Serious 27 Male 7/14/2009 Other Health Professional South Africa
Primary
Secondary

Drug Data