Clofarabine combined with Cytarabine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Death 9/1/2005 67 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/7/2005 74 Male 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 9/7/2005 71 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Death 3/7/2005 73 Male 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 1/1/2005 72 Male 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/9/2005 80 Male 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 4/29/2005 78 Male 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/25/2005 67 Male 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/18/2005 66 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 11/30/2005 4 Male 1/31/2006 Physician Spain
Primary
Concomitant
Skin Exfoliation Death 12/1/2005 37 Male 198 lb 2/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/3/2005 7 Female 2/9/2006 France
Primary
Secondary
Concomitant
Zinc Deficiency Death 12/1/2005 37 Male 198 lb 2/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/30/2005 4 Male 2/24/2006 Physician Spain
Primary
Concomitant
Platelet Count Decreased 9/12/2005 77 Male 1/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased 8/1/2005 21 1/25/2006 Physician United States
Primary
Secondary
Skin Exfoliation 12/1/2005 37 Male 198 lb 1/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Death 77 Female 3/14/2006 Physician United States
Primary
Secondary
Sepsis Death 66 Male 3/7/2006 Physician United States
Primary
Secondary
Skin Toxicity Hospitalization 1/22/2006 15 Female 3/20/2006 Spain
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 11/30/2005 4 Male 3/27/2006 Spain
Primary
Concomitant
Vomiting Hospitalization 12/3/2005 7 Female 3/30/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 2/28/2006 74 Male 4/11/2006 Physician United States
Primary
Concomitant
Sepsis Death 4/28/2006 Other Health Professional United States
Primary
Secondary
Sepsis Death 5/1/2006 Physician United States
Primary
Secondary
Skin Toxicity Hospitalization 1/30/2006 15 Female 5/1/2006 Spain
Primary
Secondary
Concomitant
Vomiting Required Intervention 5/21/2005 74 Female 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/25/2006 60 Male 198 lb 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2006 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Tracheal Haemorrhage Hospitalization 5/31/2006 69 Male 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 6/11/2006 64 Male 6/27/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 5/21/2005 74 Female 6/27/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 10/11/2005 78 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 5/31/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 11/9/2005 NotSpecified 7/18/2006 Physician United States
Primary
Secondary
Vomiting Required Intervention 6/9/2006 48 Female 227 lb 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2005 NotSpecified 7/24/2006 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 61 Male 7/28/2006 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 7/28/2006 Physician United States
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 7/28/2006 Physician United States
Primary
Secondary
Sepsis Hospitalization 68 Male 7/28/2006 Physician United States
Primary
Secondary
Sepsis Hospitalization 7/28/2006 Physician United States
Primary
Secondary
Sepsis Hospitalization 7/28/2006 Physician United States
Primary
Secondary
Fungal Sepsis Hospitalization 7/28/2006 Physician United States
Primary
Secondary
Sepsis Death 7/16/2006 67 Male 8/2/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 67 Female 7/28/2006 Physician United States
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome 6/19/2006 Male 7/26/2006 Other Health Professional United States
Primary
Secondary
Bone Marrow Failure 3/29/2006 70 Female 7/26/2006 Other Health Professional United States
Primary
Secondary
Bone Marrow Failure 12/1/2005 70 Female 7/26/2006 Other Health Professional United States
Primary
Secondary
Respiratory Failure Hospitalization 1/1/2004 77 Female 8/21/2006 Physician United States
Primary
Secondary
Febrile Neutropenia Other Serious 7/11/2006 71 Male 8/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 7/16/2006 67 Male 9/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 49 Male 209 lb 10/16/2006 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 1/1/2006 23 Male 141 lb 10/20/2006 Physician United States
Primary
Secondary
Vomiting Hospitalization 1/1/2006 23 Male 141 lb 11/1/2006 Physician United States
Primary
Secondary
Tricuspid Valve Incompetence Required Intervention 11/2/2006 64 Male 11/9/2006 Physician United States
Primary
Secondary
Tricuspid Valve Incompetence Required Intervention 11/2/2006 64 Male 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Vaginal Cellulitis Other Serious 11/17/2006 26 Female 11/27/2006 Physician United States
Primary
Secondary
Concomitant
Vaginal Cellulitis Other Serious 11/17/2006 26 Female 12/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 23 Male 141 lb 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Required Intervention 10/29/2006 70 Male 12/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Cellulitis Required Intervention 11/17/2006 26 Female 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Required Intervention 11/2/2006 64 Male 12/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 23 Male 141 lb 12/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/17/2006 26 Female 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Required Intervention 8/29/2006 26 Male 185 lb 8/31/2006 United States
Primary
Concomitant
Sepsis Death 1/3/2007 67 Male 1/9/2007 Other Health Professional United States
Primary
Secondary
Vaginal Cellulitis Required Intervention 11/17/2006 26 Female 1/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Disability 11/29/2006 57 Female 1/31/2007 United Kingdom
Primary
Secondary
Neutrophil Count Abnormal Life Threatening 2/6/2007 68 Female 2/12/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Disability 11/29/2006 57 Female 2/12/2007 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 1/31/2007 9 Female 52 lb 3/5/2007 Physician United States
Primary
Secondary
Concomitant
Transplant Other Serious Female 3/27/2007 Physician United States
Primary
Secondary
Neurotoxicity Other Serious 12/4/2006 65 Female 1/22/2007 Physician United States
Primary
Secondary
Staphylococcal Infection Disability 11/29/2006 57 Female 3/28/2007 United Kingdom
Primary
Secondary
Serratia Sepsis Required Intervention 3/1/2007 24 Female 224 lb 4/2/2007 Physician United States
Primary
Secondary
Neurotoxicity Other Serious 12/4/2006 65 Female 1/22/2007 Physician United States
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Required Intervention 6/20/2007 28 Female 108 lb 6/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pancreatitis Life Threatening 10/7/2007 14 Male 203 lb 10/15/2007 Physician United States
Primary
Secondary
Pseudomonas Infection Hospitalization 10/13/2007 Male 182 lb 11/21/2007 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 3/31/2008 54 Male 164 lb 5/5/2008 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 4/18/2008 58 Female 5/16/2008 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 9 Female 7/3/2008
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 1/1/2008 63 Female 141 lb 8/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 3/4/2008 Male 150 lb 8/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 14 Male 11/27/2008 Physician United States
Primary
Secondary
Concomitant
Sudden Death Hospitalization 14 Male 1/5/2009 Other Health Professional United States
Primary
Secondary
Unresponsive To Stimuli Other Serious 14 Male 1/29/2009 Other Health Professional United States
Primary
Secondary
Rash Maculo-papular Hospitalization 3/27/2009 4/14/2009 Germany
Primary
Secondary
Concomitant
Rash Required Intervention 12/19/2008 69 Male 190 lb 1/6/2009 Pharmacist United States
Primary
Concomitant
Rash Maculo-papular Hospitalization 3/27/2009 68 5/19/2009 Germany
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 3/27/2009 68 6/24/2009 Germany
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 14 Male 12/29/2009 Other Health Professional United States
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome 1/26/2010 Female 182 lb 2/10/2010 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 9/1/2009 43 Female 194 lb 2/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Shock Required Intervention 9/9/2009 45 Female 3/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 3/14/2010 7 Male 45 lb 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 9/1/2009 43 Female 194 lb 4/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 1/1/2008 63 Female 141 lb 6/22/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 5/7/2010 64 Male 178 lb 7/6/2010 Physician United States
Primary
Secondary
Toxic Encephalopathy Other Serious 4/1/2010 49 Female 7/9/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 4/1/2010 49 Female 7/15/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 4/29/2010 49 Female 7/19/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Lipase Increased Other Serious 6/24/2010 20 Female 155 lb 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 4/1/2010 49 Female 119 lb 7/27/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 4/1/2010 49 Female 119 lb 7/27/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 4/29/2010 49 Female 7/28/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Septic Shock Other Serious 7/14/2010 45 Female 104 lb 7/28/2010 Physician France
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 6/26/2010 40 Male 313 lb 8/9/2010 Physician United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 6/24/2010 20 Female 159 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 8/20/2010 Physician United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 6/24/2010 20 Female 159 lb 9/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 7/14/2010 45 Female 104 lb 9/9/2010 Physician France
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Death 17 Male 9/16/2010 Physician Argentina
Primary
Secondary
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 9/24/2010 Physician United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 8/30/2010 45 Male 154 lb 9/28/2010 Other Health Professional France
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 8/30/2010 45 Male 154 lb 10/6/2010 Other Health Professional France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 7/14/2010 45 Female 104 lb 10/12/2010 Physician France
Primary
Secondary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 10/14/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 8/12/2010 72 Male 10/22/2010 Consumer Japan
Primary
Secondary
Pneumonia Other Serious 10/28/2010 Physician Italy
Primary
Secondary
Pneumonia Life Threatening 8/12/2010 72 Male 11/5/2010 Consumer Japan
Primary
Secondary
Encephalitis Other Serious 9/1/2010 38 Female 11/9/2010 Other Health Professional France
Primary
Concomitant
Streptococcal Bacteraemia Death 1/13/2010 60 Male 161 lb 11/29/2010 Physician Hong Kong
Primary
Secondary
Toxoplasmosis Other Serious 19 Male 12/28/2010 Other Health Professional Switzerland
Primary
Secondary
Septic Shock Death 9/1/2009 43 Female 194 lb 1/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Death 9/1/2009 1/17/2011 Consumer United States
Primary
Secondary
Concomitant
Encephalitis Other Serious 9/1/2010 38 Female 2/8/2011 Other Health Professional France
Primary
Concomitant
Pneumonia Other Serious 2/14/2011 Physician Italy
Primary
Secondary
Renal Failure Hospitalization 8/23/2009 63 Female 262 lb 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Kussmaul Respiration Life Threatening 10/19/2007 62 Male 3/2/2011 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 3/5/2007 68 Male 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Prerenal Failure Hospitalization 12/4/2009 82 Male 170 lb 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 2/16/2007 62 Male 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/28/2006 68 Male 181 lb 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 11/25/2007 70 Female 3/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 12/3/2007 74 Male 3/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dysphagia Other Serious 2/3/2007 76 Male 3/2/2011 Physician United States
Primary
Secondary
Concomitant
Fungal Infection Disability 5/24/2007 77 Male 214 lb 3/3/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 3/10/2007 73 Male 179 lb 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 10/11/2009 59 Female 190 lb 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Life Threatening 2/10/2007 79 Male 155 lb 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/12/2011 Physician China
Primary
Secondary
Leukoencephalopathy Other Serious 8/4/2010 13 Female 99 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/21/2011 15 Male 5/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 9/1/2010 38 Female 5/9/2011 Other Health Professional France
Primary
Concomitant
Neutropenic Sepsis Death 5/10/2011 50 Male 6/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data