Clofarabine combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Hospitalization 12/13/2005 27 Female 136 lb 1/10/2006 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 12/13/2005 27 Female 136 lb 2/1/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Death 4/9/2006 Female 214 lb 4/10/2006 Other Health Professional United States
Primary
Secondary
Rash Hospitalization 12/13/2005 27 Female 136 lb 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Death 4/9/2006 Female 214 lb 4/10/2006 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 4/19/2006 5 Male 40 lb 4/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 4/19/2006 5 Male 40 lb 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Virus Urine Test Positive Hospitalization 4/19/2006 5 Male 40 lb 5/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 5/4/2006 72 Female 5/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 5/4/2006 72 Female 6/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 4/17/2006 70 Male 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 5/4/2006 72 Female 7/13/2006 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 7/23/2006 60 Male 8/8/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2006 72 Female 8/21/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/5/2006 8/22/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 7/21/2006 6 Female 47 lb 8/22/2006 Physician United States
Primary
Secondary
Concomitant
Virus Urine Test Positive Required Intervention 7/21/2006 6 Female 47 lb 9/1/2006 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/12/2006 72 Female 113 lb 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2006 33 Female 9/1/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 7/23/2006 60 Male 9/5/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/5/2006 59 Female 143 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 59 Female 143 lb 9/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 59 Female 143 lb 9/25/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/24/2006 58 Male 9/26/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/17/2006 5 Male 42 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Transfusion Reaction Required Intervention 8/18/2006 9 Female 56 lb 10/19/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/17/2006 5 Male 42 lb 11/3/2006 United States
Primary
Secondary
Concomitant
Stem Cell Transplant Required Intervention 8/18/2006 9 Female 56 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/22/2006 11 Female 75 lb 11/22/2006 Physician United States
Primary
Secondary
Concomitant
Vaginal Cellulitis Other Serious 11/17/2006 26 Female 11/27/2006 Physician United States
Primary
Secondary
Concomitant
Vaginal Cellulitis Other Serious 11/17/2006 26 Female 12/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Cellulitis Required Intervention 11/17/2006 26 Female 12/18/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/17/2006 26 Female 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Hospitalization 10/22/2006 11 Female 75 lb 1/18/2007 Physician United States
Primary
Secondary
Concomitant
Vaginal Cellulitis Required Intervention 11/17/2006 26 Female 1/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/22/2007 5 Female 27 lb 2/7/2007 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/22/2007 5 Female 27 lb 2/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/22/2007 5 Female 27 lb 2/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/31/2007 9 Female 52 lb 3/5/2007 Physician United States
Primary
Secondary
Concomitant
X-ray Gastrointestinal Tract Abnormal Hospitalization 1/22/2007 5 Female 27 lb 4/10/2007 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 4/9/2007 19 Male 167 lb 6/4/2007 Physician United States
Primary
Secondary
Concomitant
Vitreous Floaters Hospitalization 1/30/2007 69 Male 205 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 10/16/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/19/2007 13 Female 82 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 11/8/2007 20 Male 118 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/17/2007 20 Female 142 lb 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/9/2007 65 Male 162 lb 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 1/1/2008 27 Female 12/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Life Threatening 1/1/2009 11 Male 3/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/15/2009 11 Male 3/24/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2009 11 Male 82 lb 3/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/16/2009 11 Male 3/30/2009 Pharmacist United Kingdom
Primary
Secondary
Sepsis Other Serious 1/1/2009 11 Male 82 lb 3/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 82 lb 4/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/16/2009 11 Male 4/21/2009 Pharmacist United Kingdom
Primary
Secondary
Vomiting Other Serious 1/6/2009 11 Male 84 lb 4/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 1/15/2009 11 Male 4/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 38 Male 5/4/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 82 lb 5/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 82 lb 5/7/2009 Pharmacist United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 7/9/2009 Other Health Professional United States
Primary
Secondary
Venoocclusive Liver Disease Other Serious 7/9/2009 Other Health Professional United States
Primary
Secondary
Venoocclusive Liver Disease Other Serious 7/9/2009 Other Health Professional United States
Primary
Secondary
Hyperbilirubinaemia Other Serious 7/9/2009 Other Health Professional United States
Primary
Secondary
Renal Impairment Other Serious 1 Female 8/24/2009 United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 1 Female 9/10/2009 United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 4/20/2009 17 Female 9/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Disease Progression Death 9/16/2009 13 Male 10/23/2009 Consumer United Kingdom
Primary
Secondary
Therapeutic Response Decreased Death 9/16/2009 13 Male 10/23/2009 Physician United Kingdom
Primary
Secondary
Mediastinal Mass Death 9/16/2009 13 Male 10/23/2009 Physician United Kingdom
Primary
Secondary
Disease Progression Death 9/16/2009 13 Male 10/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
T-cell Lymphoma Death 9/16/2009 13 Male 10/29/2009 Physician United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 4/20/2009 17 Female 11/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Disease Progression Death 9/16/2009 13 Male 106 lb 11/24/2009 Consumer United Kingdom
Primary
Secondary
Renal Impairment Other Serious 2 Female 11/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 2 Female 12/2/2009 United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 2 Female 11/24/2009 United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Death 9/16/2009 13 Male 106 lb 12/2/2009 Consumer United Kingdom
Primary
Secondary
Renal Impairment Other Serious 1 Female 11/30/2009 United Kingdom
Primary
Secondary
Renal Impairment Other Serious 2 Female 12/2/2009 United Kingdom
Primary
Secondary
Vomiting Life Threatening 1/3/2009 11 Male 83 lb 1/25/2010 Pharmacist United Kingdom
Primary
Secondary
Sepsis Death 1/15/2009 11 Male 83 lb 1/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 12/3/2009 Male 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 12/8/2009 11 Male 82 lb 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 9/19/2009 17 Male 198 lb 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
White Blood Cell Count Decreased Hospitalization 9/17/2006 5 Male 42 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/6/2009 16 Male 209 lb 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 5/7/2010 4 Female 7/2/2010 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 7/2/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Fungal Other Serious 5/18/2010 5 Female 57 lb 7/7/2010 Physician United States
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious 7/8/2010 Other Health Professional United States
Primary
Secondary
Septic Shock Life Threatening 9/29/2009 15 Male 240 lb 7/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Fungal Other Serious 5/18/2010 5 Female 57 lb 7/14/2010 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 9/19/2009 17 Male 198 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Septic Shock Life Threatening 9/29/2009 15 Male 240 lb 7/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 9/19/2009 17 Male 198 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 8/11/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Fungal Other Serious 5/18/2010 5 Female 57 lb 8/13/2010 Physician United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 8/20/2010 Physician United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/25/2010 61 Female 187 lb 9/23/2010 Other Health Professional France
Primary
Secondary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 9/24/2010 Physician United States
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 4/9/2010 4 Female 10/6/2010 Consumer United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 10/14/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/8/2009 11 Male 82 lb 10/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Encephalitis Other Serious 9/1/2010 38 Female 11/9/2010 Other Health Professional France
Primary
Concomitant
Respiratory Syncytial Virus Test Positive Life Threatening 11/16/2010 14 Female 130 lb 11/24/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Life Threatening 11/16/2010 14 Female 130 lb 12/3/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 11/16/2010 14 Female 130 lb 12/17/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Fungal Other Serious 5/18/2010 5 Female 57 lb 12/22/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 4/18/2010 18 Female 223 lb 12/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 11/16/2010 14 Female 130 lb 12/27/2010 Physician United States
Primary
Secondary
Concomitant
Toxoplasmosis Other Serious 19 Male 12/28/2010 Other Health Professional Switzerland
Primary
Secondary
Bone Marrow Failure Death 5/18/2010 5 Female 57 lb 1/5/2011 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Life Threatening 11/16/2010 14 Female 130 lb 1/5/2011 Physician United States
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious 1/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 4/18/2010 18 Female 223 lb 2/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Encephalitis Other Serious 9/1/2010 38 Female 2/8/2011 Other Health Professional France
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/16/2010 14 Female 130 lb 3/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fungal Skin Infection Hospitalization 5/18/2010 5 Female 57 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 8/4/2010 13 Female 99 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 9/1/2010 38 Female 5/9/2011 Other Health Professional France
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 4/1/2011 Physician United States
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 6/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis Fungal Other Serious 7/13/2011 Physician United States
Primary
Secondary
Graft Versus Host Disease Death Female 7/15/2011 Physician Malaysia
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death Female 7/15/2011 Physician Malaysia
Primary
Secondary
Concomitant
Eyelid Oedema Other Serious 7/7/2011 1 Male 8/4/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Graft Versus Host Disease Death Female 8/5/2011 Physician Malaysia
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death Female 8/5/2011 Physician Malaysia
Primary
Secondary
Concomitant
Graft Versus Host Disease Death Female 8/22/2011 Consumer Singapore
Primary
Secondary
Concomitant
Haemoglobin Decreased Death 12/1/2009 11 Female 8/22/2011 Consumer Singapore
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 12/1/2009 11 Female 8/22/2011 Physician Singapore
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 12/1/2009 11 Female 9/23/2011 Physician Singapore
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/8/2011 30 Male 9/26/2011 Other Health Professional France
Primary
Secondary
Sepsis Death 9/20/2011 2 Male 33 lb 9/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Capillary Leak Syndrome Death 11 Male 90 lb 10/11/2011 Physician Colombia
Primary
Secondary
Concomitant
Sepsis Other Serious 9/19/2011 2 Male 33 lb 10/19/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Other Serious 9/17/2011 16 Female 117 lb 10/19/2011 Physician France
Primary
Secondary
Concomitant
Septic Shock Other Serious 9/17/2011 16 Female 117 lb 11/7/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 8/7/2010 Female 16 lb 11/29/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pulmonary Oedema Death 1/4/2012 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Death 1/4/2012 Other Health Professional United States
Primary
Secondary
Septic Shock Death 1/4/2012 Other Health Professional United States
Primary
Secondary
Venoocclusive Disease Death 1/4/2012 Other Health Professional United States
Primary
Secondary
Venoocclusive Disease Death 1/4/2012 Other Health Professional United States
Primary
Secondary
Septic Shock Death 1/4/2012 Other Health Professional United States
Primary
Secondary

Drug Data