Clarithromycin combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Visual Field Defect Other Serious 1/1/2006 74 Male 2/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 62 Female 3/10/2006 United Kingdom
Primary
Interacting
Vitreous Opacities Other Serious 62 Female 3/22/2006 United Kingdom
Primary
Interacting
Vitreous Opacities Other Serious 62 Female 3/22/2006 United Kingdom
Primary
Interacting
Vomiting Other Serious 56 Female 4/18/2006 Physician Pakistan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 3/1/2006 57 Male 4/18/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Required Intervention 69 Female 5/5/2006 Physician United Kingdom
Primary
Concomitant
Ulcer Haemorrhage Other Serious 3/1/2006 57 Male 115 lb 5/5/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Other Serious 69 Female 5/11/2006 Other Health Professional United Kingdom
Primary
Interacting
Retroperitoneal Haematoma Other Serious 69 Female 5/18/2006 Other Health Professional United Kingdom
Primary
Interacting
International Normalised Ratio Increased Other Serious Female 6/9/2006 United States
Primary
Secondary
Viral Infection Hospitalization 69 Female 176 lb 6/16/2006 Canada
Primary
Concomitant
Interacting
Retroperitoneal Haematoma Hospitalization 69 Female 6/14/2006 United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 11/17/2005 85 Female 110 lb 6/30/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 11/17/2005 Female 110 lb 7/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Complication Required Intervention 1/31/2006 37 Female 123 lb 10/4/2006 Physician Japan
Primary
Concomitant
Oesophageal Ulcer Hospitalization 80 Male 10/26/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 80 Male 11/3/2006 United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 80 Male 11/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 80 Male 11/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Other Serious 80 Male 11/9/2006 United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 10/12/2006 65 Female 106 lb 12/1/2006 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 10/12/2006 65 Female 106 lb 12/15/2006 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 11/13/2006 54 Male 213 lb 1/22/2007 Other Health Professional United States
Primary
Concomitant
Nephritis Interstitial Hospitalization 4/20/2006 61 Female 1/31/2007 United Kingdom
Primary
Secondary
Concomitant
Nephritis Interstitial Hospitalization 4/20/2006 61 Female 2/2/2007 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 10/2/2006 52 Male 154 lb 11/22/2006 Other Health Professional United States
Primary
Secondary
International Normalised Ratio Increased Hospitalization 11/11/2006 Male 152 lb 11/30/2006 Pharmacist United States
Primary
Secondary
Nephritis Interstitial Hospitalization 4/20/2006 61 Female 2/15/2007 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 10/18/2006 Male 2/28/2007 Physician Norway
Primary
Interacting
Pneumonia Other Serious 10/18/2006 Male 2/28/2007 Physician Norway
Primary
Interacting
Nephritis Interstitial Hospitalization 4/20/2006 61 Female 121 lb 2/28/2007 United Kingdom
Primary
Secondary
Concomitant
Sensation Of Heaviness Hospitalization 3/1/2007 51 Male 3/16/2007 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 65 Male 4/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Oedema Peripheral Other Serious 65 Male 4/6/2007 United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 65 Male 4/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Death 11/24/2006 39 Male 179 lb 4/19/2007 Consumer United Kingdom
Primary
Concomitant
Retroperitoneal Haematoma Hospitalization 69 Female 5/16/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/7/2007 79 Male 5/24/2007 Other Health Professional Italy
Primary
Concomitant
Retroperitoneal Haematoma Other Serious 69 Female 6/7/2007 United States
Primary
Concomitant
Interacting
Mania Other Serious 6/1/2007 73 Male 6/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Menorrhagia Hospitalization 6/26/2007 38 Female 112 lb 7/10/2007 Physician Japan
Primary
Concomitant
Therapeutic Product Ineffective Hospitalization 78 Male 198 lb 7/16/2007
Primary
Secondary
General Physical Health Deterioration Hospitalization 78 Male 8/27/2007 Physician Belgium
Primary
Secondary
Concomitant
Hyphaema Other Serious 62 Female 9/5/2007 United Kingdom
Primary
Secondary
International Normalised Ratio Increased Other Serious 62 Female 9/5/2007 United Kingdom
Primary
Secondary
Visual Acuity Reduced Other Serious 62 Female 9/20/2007 United Kingdom
Primary
Secondary
Visual Acuity Reduced Other Serious 62 Female 9/27/2007 Other Health Professional United Kingdom
Primary
Secondary
International Normalised Ratio Increased Other Serious 2 Male 10/9/2007 Physician Saudi Arabia
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/6/2007 Male 10/19/2007 Physician United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 10/8/2007 Male 11/5/2007 Physician Japan
Primary
Secondary
Concomitant
Tremor Other Serious 9/14/2007 75 Male 146 lb 11/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 9/14/2007 75 Male 146 lb 11/15/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Melaena Hospitalization 7/25/2007 76 Male 11/16/2007 Consumer Italy
Primary
Secondary
Concomitant
Obstructive Airways Disorder Life Threatening 9/14/2007 75 Male 146 lb 11/16/2007 United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 9/14/2007 75 Male 11/16/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/6/2007 Male 12/18/2007 Physician United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 10/8/2007 Male 112 lb 12/26/2007 Physician Ireland
Primary
Concomitant
Urticaria Hospitalization 12/20/2007 63 Male 12/27/2007 Pharmacist United States
Primary
Secondary
Respiratory Failure Hospitalization 3/26/2007 Male 141 lb 2/26/2008 Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 2/3/2007 Male 141 lb 3/17/2008 Japan
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2006 Female 3/31/2008 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haematoma Hospitalization 69 Female 4/28/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 4/18/2008 87 Male 168 lb 5/21/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 4/18/2008 5/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 4/18/2008 87 Male 168 lb 5/22/2008 United Kingdom
Primary
Concomitant
Vena Cava Injury Death 2/8/2008 Female 180 lb 6/10/2008 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 Male 6/25/2008 Physician Japan
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 4/18/2008 87 Male 8/9/2008 United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 11/24/2006 39 Male 179 lb 8/21/2008 Consumer United Kingdom
Primary
Concomitant
Mania Other Serious 6/1/2007 73 Male 8/26/2008 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 11/14/2008 90 Male 11/20/2008 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious 11/4/2008 Male 12/23/2008 Physician France
Primary
Concomitant
Interacting
Toxic Skin Eruption Hospitalization 11/14/2008 67 Male 1/29/2009 Consumer Japan
Primary
Concomitant
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 2/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 12/2/2008 62 Female 187 lb 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/10/2009 82 Male 4/21/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/22/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/27/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/29/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 1/6/2009 79 Female 5/1/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Tonic Convulsion Hospitalization 3/10/2009 82 Male 5/6/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Myositis Hospitalization 1/17/2009 79 Female 5/1/2009
Primary
Secondary
Concomitant
Syncope Hospitalization 1/6/2009 79 Female 5/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 5/13/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Syncope Death 79 Female 5/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Death 1/6/2009 79 Female 5/18/2009 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 4/28/2009 86 Male 176 lb 5/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 67 Male 6/17/2009 United States
Primary
Concomitant
Sequestrectomy Hospitalization 2/1/2009 Male 150 lb 6/26/2009 Physician Japan
Primary
Concomitant
Gout Other Serious 3/12/2009 72 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Gout Required Intervention 3/12/2009 72 Female 6/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/16/2009 81 Male 254 lb 6/2/2009 Pharmacist United States
Primary
Secondary
Tonic Convulsion Hospitalization 3/8/2009 82 Male 7/24/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/21/2008 66 Male 179 lb 7/21/2009 United States
Primary
Concomitant
Wound Abscess Other Serious 1/9/2009 Male 8/3/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 8/5/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 9/2/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 9/2/2009 United States
Primary
Concomitant
International Normalised Ratio Abnormal Other Serious 7/30/2009 67 Female 9/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 7/30/2009 67 Female 9/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal Other Serious 7/30/2009 67 Female 9/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
International Normalised Ratio Abnormal Other Serious 7/30/2009 67 Female 9/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Staphylococcal Death 5/18/2009 77 Male 9/29/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 7/30/2009 Male 10/15/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 10/17/2009 United States
Primary
Concomitant
Syncope Death 1/6/2009 79 Female 10/23/2009 United Kingdom
Primary
Concomitant
Vasodilatation Male 10/26/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 5/1/2009 97 Male 11/6/2009 Consumer Australia
Primary
Secondary
Concomitant
Interacting
Vasodilatation 43 Male 11/4/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 11/4/2009 United States
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 4/20/2006 61 Female 121 lb 11/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 61 Female 11/17/2009 Lawyer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2009 Male 12/21/2009 Pharmacist Ireland
Primary
Concomitant
Pallor Hospitalization 75 Male 1/22/2010 Lawyer United States
Primary
Concomitant
Vision Blurred Hospitalization 43 Male 2/17/2010 United States
Primary
Concomitant
Tooth Infection Other Serious 3/4/1996 25 Female 5/27/2010 Pharmacist United States
Primary
Secondary
Concomitant
Wheezing Other Serious 10/29/2008 57 Female 120 lb 8/3/2010 Consumer United States
Primary
Concomitant
Off Label Use Other Serious 5/25/2010 73 Female 130 lb 9/13/2010 Consumer United States
Primary
Concomitant
Vaginitis Bacterial Other Serious 3/4/1996 25 Female 9/28/2010 Pharmacist United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 5/25/2010 73 Female 130 lb 9/30/2010 Consumer United States
Primary
Concomitant
5Q Minus Syndrome Other Serious 12/10/2009 70 Male 10/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 5/25/2010 73 Female 130 lb 10/21/2010 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/12/2008 34 Female 154 lb 11/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 80 Female 12/16/2010 Consumer Australia
Primary
Secondary
Concomitant
Radiculitis Lumbosacral Hospitalization 3/4/1996 25 Female 1/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 4/12/2008 33 Female 154 lb 1/28/2011 Other Health Professional United States
Primary
Concomitant
Potentiating Drug Interaction Other Serious 2/4/2011 Physician United Kingdom
Primary
Interacting
Muscle Haemorrhage Other Serious 12/30/2010 74 Female 134 lb 2/4/2011 Physician United Kingdom
Primary
Concomitant
Interacting
Drug Dispensing Error Other Serious 2/4/2011 Physician United Kingdom
Primary
Interacting
Drug Dispensing Error Other Serious 2/4/2011 Physician United Kingdom
Primary
Interacting
Haemoglobin Decreased Hospitalization 12/30/2010 74 Female 134 lb 2/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Potentiating Drug Interaction Hospitalization 12/30/2010 74 Female 134 lb 2/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peripheral Ischaemia Life Threatening 6/21/2010 76 Male 251 lb 2/15/2011 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 74 Female 2/11/2011 United Kingdom
Primary
Secondary
Concomitant
Myositis Other Serious 1/6/2009 79 Female 3/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Increased Hospitalization 72 Male 4/22/2011 Physician
Primary
Secondary
Concomitant
Cardiac Failure Death 12/7/2010 85 Female 5/3/2011 Physician Italy
Primary
Concomitant
Interacting
Acute Pulmonary Oedema Hospitalization 4/1/2011 83 Female 155 lb 5/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Muscular Weakness Hospitalization 77 Female 124 lb 4/29/2011 Consumer United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 4/18/2011 73 Female 5/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Embolic Cerebral Infarction Other Serious Female 5/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Helicobacter Test Positive Hospitalization 7/30/2009 69 Female 88 lb 5/26/2011 Physician Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Death 3/30/2011 73 Male 120 lb 6/1/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Death 3/30/2011 73 Male 120 lb 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Pharyngitis Other Serious 3/4/1996 25 Female 6/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Embolic Cerebral Infarction Hospitalization 4/24/2011 65 Female 104 lb 7/6/2011 Physician Japan
Primary
Concomitant
Epistaxis Hospitalization 3/28/2011 90 Female 7/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 3/28/2011 90 Female 7/7/2011 Pharmacist United Kingdom
Primary
Concomitant
Interacting

Drug Data