Clarithromycin combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Muscular Weakness Life Threatening 11/10/2005 85 Female 110 lb 2/23/2006 Other Health Professional Japan
Primary
Concomitant
Death Death 3/1/2006 51 Female 4/12/2006 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2005 73 Female 4/20/2006 Physician Japan
Primary
Secondary
Death Death 3/28/2006 51 Female 5/1/2006 United States
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 2/4/2004 Female 6/15/2006 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 3/1/2005 63 Female 8/17/2006 Physician United States
Primary
Concomitant
Hepatorenal Failure Death 8/12/2006 4 Male 9/1/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Hepatorenal Failure Death 8/12/2006 4 Male 9/1/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Hepatorenal Failure Death 8/18/2006 4 Male 9/13/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/29/2006 64 Female 11/1/2006 Consumer United Kingdom
Primary
Concomitant
Pigmentation Disorder Hospitalization 7/18/2006 77 Female 103 lb 12/4/2006 Physician Japan
Primary
Concomitant
Pigmentation Disorder Hospitalization 7/18/2006 77 Female 103 lb 12/15/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/24/2006 Female 139 lb 3/5/2007 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/24/2006 Female 139 lb 3/9/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/21/2007 0 Male 3/12/2007 Japan
Primary
Concomitant
Spinal Fracture Other Serious 11/2/2006 Male 115 lb 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/2/2006 Male 115 lb 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/2/2006 Male 115 lb 4/13/2007 Physician Canada
Primary
Secondary
Concomitant
Urine Output Decreased Disability 2/21/2007 0 Male 4/13/2007 Japan
Primary
Concomitant
Tachypnoea Life Threatening 12/21/2006 0 Male 10/5/2007 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 12/21/2006 0 Male 10/19/2007 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 11/20/2007 Germany
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 4/16/2008 Germany
Primary
Concomitant
Peritonitis Bacterial Hospitalization 72 Male 5/1/2008 Physician Spain
Primary
Concomitant
Peritonitis Bacterial Hospitalization 72 Male 5/2/2008 Physician Spain
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 5/9/2008 Germany
Primary
Concomitant
Sepsis Hospitalization 1/29/2008 74 Male 6/13/2008 Physician Canada
Primary
Concomitant
Blood Glucose Increased Other Serious 5/9/2008 41 Male 8/4/2008 Physician Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 5/9/2008 41 Male 8/26/2008 Physician Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 5/9/2008 41 Male 9/8/2008 Physician Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 5/9/2008 41 Male 9/12/2008 Physician Japan
Primary
Concomitant
Pulmonary Haemorrhage Life Threatening 9/23/2004 22 Male 10/15/2008 Physician Japan
Primary
Concomitant
Pulmonary Haemorrhage Life Threatening 9/23/2004 22 Male 11/19/2008 Physician Japan
Primary
Concomitant
Hepatitis Acute Other Serious Male 1/15/2009 Physician Germany
Primary
Secondary
Hepatitis Acute Other Serious Male 1/12/2009 Physician Germany
Primary
Secondary
Concomitant
Sinoatrial Block Life Threatening 8/18/2008 66 Female 198 lb 1/16/2009 Physician Germany
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious Male 1/16/2009 Other Health Professional Germany
Primary
Secondary
Sinoatrial Block Other Serious 8/18/2008 66 Female 198 lb 1/20/2009 Physician Germany
Primary
Secondary
Concomitant
Interacting
Sinoatrial Block Life Threatening 8/18/2008 66 Female 198 lb 1/21/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Sinoatrial Block Other Serious 8/18/2008 66 Female 1/23/2009 Physician United States
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious Male 1/16/2009 Germany
Primary
Secondary
Sinoatrial Block Other Serious 8/18/2008 66 Female 1/28/2009 Physician United States
Primary
Secondary
Concomitant
Sinoatrial Block Life Threatening 66 Female 1/26/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Sinoatrial Block Life Threatening 66 Female 1/23/2009 Germany
Primary
Secondary
Concomitant
Respiratory Failure Disability 3/31/2009 77 Female 77 lb 5/14/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 4/14/2009 77 Female 77 lb 5/29/2009 Physician Japan
Primary
Concomitant
Pulmonary Haemorrhage Life Threatening 9/23/2004 Male 7/1/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 53 Female 9/29/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 60 Female 9/29/2009 United States
Primary
Concomitant
Respiratory Failure Life Threatening 4/14/2009 77 Female 77 lb 12/23/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 60 Female 1/22/2010 United States
Primary
Concomitant
Myocardial Infarction Other Serious 10/27/2010 52 Male 11/1/2010 Consumer
Primary
Concomitant
Sinoatrial Block Life Threatening 8/18/2008 66 Female 198 lb 11/29/2010 Physician Germany
Primary
Secondary
Concomitant
Interacting
Renal Failure Life Threatening 8/18/2008 66 Female 198 lb 12/6/2010 Physician Germany
Primary
Secondary
Concomitant
Breast Cancer Female Life Threatening 4/8/2010 12/6/2010 Physician Japan
Primary
Concomitant
Sinoatrial Block Life Threatening 8/18/2008 66 Female 198 lb 12/9/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Diarrhoea Life Threatening 8/18/2008 66 Female 12/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Diarrhoea Life Threatening 8/18/2008 66 Female 12/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Radial Pulse Decreased Death 70 Female 119 lb 3/11/2011 Other Health Professional Brazil
Primary
Secondary
Concomitant
Chest Discomfort Hospitalization 1/1/2006 36 Female 195 lb 3/21/2011 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/30/2007 41 Female 261 lb 4/29/2011 Lawyer United States
Primary
Concomitant
Cardiac Failure Death 12/7/2010 85 Female 5/3/2011 Physician Italy
Primary
Concomitant
Interacting
Dystonia Other Serious 7/1/2009 58 Female 175 lb 5/23/2011 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization Female 126 lb 6/6/2011 Lawyer United States
Primary
Concomitant
Diarrhoea Life Threatening 8/18/2008 66 Female 198 lb 6/13/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/13/2011 75 Male 7/25/2011 Pharmacist Japan
Primary
Concomitant
Carbon Dioxide Increased Hospitalization 7/13/2011 75 Male 8/1/2011 Physician Japan
Primary
Concomitant
Salivary Hypersecretion Disability 7/13/2011 75 Male 143 lb 9/19/2011 Pharmacist Japan
Primary
Concomitant
Cough Hospitalization 83 Male 9/29/2011 Physician Canada
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 83 Male 9/30/2011 Physician Canada
Primary
Secondary
Carbon Dioxide Increased Other Serious 7/13/2011 75 Male 143 lb 10/27/2011 Pharmacist Japan
Primary
Concomitant
Death Death 59 Male 11/4/2011 Physician Sweden
Primary
Concomitant
Interacting
Gastric Haemorrhage Hospitalization 10/6/2011 73 Female 11/10/2011 Pharmacist United States
Primary
Concomitant
Blood Creatinine Increased Death 75 Male 132 lb 11/11/2011 Pharmacist Australia
Primary
Secondary
Concomitant
Drug Interaction Death 59 Male 11/28/2011 Physician Sweden
Primary
Concomitant
Interacting
Agranulocytosis Death 5/31/2011 59 Male 12/2/2011 Physician Sweden
Primary
Concomitant
Interacting
Cardiac Arrest Death 5/1/2011 59 Male 12/9/2011 Physician Sweden
Primary
Concomitant
Interacting
Hallucination, Visual Other Serious 11/22/2011 89 Male 229 lb 12/13/2011 Physician United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 11/22/2011 89 Male 229 lb 12/14/2011 Physician United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 11/22/2011 89 Male 229 lb 12/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 11/22/2011 89 Male 229 lb 12/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 11/22/2011 89 Male 229 lb 12/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 11/22/2011 89 Male 12/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Arthralgia Other Serious 1/1/2008 24 Female 12/30/2011 Other Health Professional United States
Primary
Concomitant
Dizziness Other Serious 83 Male 1/10/2012 Other Health Professional Canada
Primary
Concomitant
Interacting
Ileus Paralytic Hospitalization 1/1/2010 64 Male 209 lb 1/4/2012 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 83 Male 1/16/2012 Other Health Professional Canada
Primary
Concomitant
Interacting
Nausea Hospitalization 83 Male 1/16/2012 Other Health Professional Canada
Primary
Concomitant
Interacting
Clostridium Colitis Hospitalization 8/25/2011 85 Female 1/19/2012 Pharmacist Italy
Primary
Secondary
Concomitant
Arrhythmia Other Serious 9/29/2009 70 Male 260 lb 1/13/2012 Lawyer United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 4/1/2010 64 Male 209 lb 1/19/2012 Physician United States
Primary
Concomitant
Clostridium Colitis Hospitalization 8/25/2011 85 Female 1/26/2012 Pharmacist Italy
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 83 Male 1/26/2012 Physician Canada
Primary
Secondary
Fatigue Hospitalization 83 Male 1/24/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Megacolon Hospitalization 8/25/2011 85 Female 1/31/2012 Pharmacist Italy
Primary
Secondary
Concomitant
Clostridium Colitis Hospitalization 8/25/2011 85 Female 2/2/2012 Pharmacist Italy
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 75 Male 132 lb 2/14/2012 Pharmacist Australia
Primary
Secondary
Concomitant
Cough Hospitalization 83 Male 2/10/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Dyspnoea Exertional Hospitalization 83 Male 2/10/2012 Physician Canada
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2011 46 Female 128 lb 2/27/2012 Physician Japan
Primary
Secondary
Concomitant
Malaise Disability 2/13/2012 75 Female 154 lb 2/28/2012 Physician United Kingdom
Primary
Concomitant
Megacolon Hospitalization 8/25/2011 85 Female 2/28/2012 Pharmacist Italy
Primary
Secondary
Concomitant
Normochromic Normocytic Anaemia Hospitalization 1/1/2012 79 Female 3/2/2012 Physician France
Primary
Secondary
Concomitant
Headache Disability 2/13/2012 75 Female 154 lb 3/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/15/2004 43 Female 126 lb 3/6/2012 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2011 84 Female 2/24/2012 Other Health Professional Germany
Primary
Concomitant
Headache Disability 2/13/2012 75 Female 154 lb 3/7/2012 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Disability 2/13/2012 75 Female 154 lb 3/8/2012 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Disability 2/13/2012 75 Female 154 lb 3/9/2012 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Life Threatening Female 3/9/2012 Consumer Australia
Primary
Concomitant
Renal Impairment Hospitalization 83 Male 3/27/2012 Canada
Primary
Concomitant
Interacting
Dizziness Hospitalization 83 Male 4/3/2012 Other Health Professional Canada
Primary
Secondary
Cough Hospitalization 83 Male 4/5/2012 Other Health Professional Canada
Primary
Concomitant
Interacting
Nausea Hospitalization 83 Male 4/5/2012 Other Health Professional Canada
Primary
Concomitant
Interacting
Cough Hospitalization 83 Male 4/5/2012 Other Health Professional Canada
Primary
Concomitant
Interacting
Liver Injury Hospitalization 4/13/2012 64 Male 132 lb 4/26/2012 Physician Estonia
Primary
Concomitant
Liver Injury Hospitalization 4/13/2012 64 Male 132 lb 5/7/2012 Physician Estonia
Primary
Concomitant
Bundle Branch Block Left Hospitalization 83 Male 5/8/2012 Physician Canada
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/26/2012 70 Male 5/18/2012 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Pulmonary Hypertension Life Threatening Male 165 lb 5/23/2012 Consumer United States
Primary
Concomitant
Nausea Hospitalization 83 Male 5/23/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/13/2011 77 Male 6/7/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Apnoea Death 2/6/2008 6/20/2012 Consumer Germany
Primary
Concomitant
Feeling Hot Other Serious 6/2/2012 79 Female 122 lb 7/14/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Scab Other Serious 5/8/2012 79 Female 122 lb 7/16/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 6/2/2012 79 Female 122 lb 7/19/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 6/2/2012 79 Female 122 lb 7/24/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Death 6/2/2012 79 Female 122 lb 7/25/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 6/2/2012 79 Female 122 lb 7/25/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Death 6/2/2012 79 Female 122 lb 7/25/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 6/2/2012 79 Female 122 lb 7/26/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Death 6/2/2012 7/26/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 6/2/2012 79 Female 122 lb 7/19/2012 Pharmacist
Primary
Secondary
Concomitant
Fluid Overload Death 6/2/2012 79 Female 7/23/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/8/2012 79 Female 122 lb 8/6/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 6/2/2012 79 Female 122 lb 8/6/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Dry Skin Hospitalization 6/2/2012 79 Female 122 lb 7/24/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 6/2/2012 79 Female 122 lb 8/9/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 6/2/2012 79 Female 8/10/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Blister Death 6/2/2012 79 Female 122 lb 8/13/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 6/2/2012 79 Female 122 lb 8/14/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Pruritic Death 6/2/2012 79 Female 122 lb 8/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 6/2/2012 79 Female 122 lb 8/17/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pain Death 6/2/2012 79 Female 122 lb 8/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Other Serious 5/8/2012 79 Female 122 lb 8/20/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 6/2/2012 79 Female 122 lb 8/21/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Petechiae Death 6/2/2012 8/21/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 5/14/2012 66 Female 8/24/2012 Consumer France
Primary
Concomitant
Urticaria Other Serious 2011 Female 128 lb 11/23/2012 Physician Jp
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 11/14/2012 Pharmacist Gb
Primary
Secondary
Concomitant

Drug Data