Clarithromycin combined with Rifampicin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pruritus Hospitalization 11/10/2005 78 Female 1/5/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/27/2005 77 Female 1/16/2006 Australia
Primary
Concomitant
Transaminases Increased Other Serious 2 Female 1/20/2006 Germany
Primary
Secondary
Somnolence Hospitalization 2 Female 1/17/2006 United States
Primary
Secondary
Respiratory Failure Hospitalization 9/1/2005 0 Male 2/2/2006 Physician France
Primary
Concomitant
Transaminases Increased Other Serious 2 Female 2/9/2006 Germany
Primary
Secondary
Streptococcal Infection Hospitalization 12/1/2000 73 Male 3/10/2006 Physician Japan
Primary
Secondary
Concomitant
Retinal Pigment Epitheliopathy Disability 4/1/2005 71 Male 4/13/2006 Consumer United States
Primary
Secondary
Concomitant
Hepatitis Cholestatic Death 3/3/2006 Male 5/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 61 Male 110 lb 6/26/2006 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 61 Male 110 lb 7/6/2006 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 12/1/2000 Male 7/18/2006 Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/1/2000 Male 7/27/2006 Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/1/2000 Male 8/1/2006 Japan
Primary
Secondary
Concomitant
Hearing Impaired Disability 5/1/2006 13 Male 82 lb 9/12/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 3/1/2006 69 Male 11/9/2006 Physician Japan
Primary
Concomitant
Pulmonary Fibrosis Death 75 Female 171 lb 12/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 75 Female 171 lb 11/29/2006 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/8/2006 Male 99 lb 1/19/2007 Physician Japan
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/9/2007 24 Female 90 lb 2/9/2007 Pharmacist United Kingdom
Primary
Concomitant
Rash Other Serious 3/1/2006 Male 137 lb 2/13/2007 Physician Japan
Primary
Concomitant
Optic Neuropathy Other Serious 10/1/2006 63 Male 165 lb 2/22/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/24/2006 Male 99 lb 3/1/2007 Japan
Primary
Concomitant
Thrombocytopenia Other Serious 4/12/2007 54 Female 5/17/2007 United States
Primary
Concomitant
Mycobacterium Abscessus Infection Hospitalization 73 Female 6/20/2007 Other Health Professional Japan
Primary
Secondary
Neutropenia Life Threatening 6/1/2007 90 Male 8/2/2007 Physician Japan
Primary
Concomitant
Eosinophilic Pneumonia Other Serious 80 Female 8/21/2007 Other Health Professional Japan
Primary
Concomitant
Eosinophilic Pneumonia Other Serious 80 Female 8/28/2007 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2006 57 Female 90 lb 8/31/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/30/2005 73 Female 9/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Paradoxical Drug Reaction Hospitalization 6/30/2007 73 Female 9/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/25/2007 Male 154 lb 10/3/2007 Physician United Kingdom
Primary
Concomitant
Pyopneumothorax Death 77 Male 11/12/2007 Physician Japan
Primary
Concomitant
Rash Other Serious 67 Female 11/21/2007 Japan
Primary
Concomitant
Pyopneumothorax Death 77 Male 11/22/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 27 Male 12/28/2007 Brazil
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/7/2007 24 Female 90 lb 2/1/2008 Pharmacist United Kingdom
Primary
Concomitant
Mycobacterium Abscessus Infection Hospitalization 73 Female 3/18/2008 Japan
Primary
Secondary
Concomitant
Death Death Male 3/19/2008 Other Health Professional Japan
Primary
Concomitant
Hepatic Failure Other Serious 32 Female 4/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hepatic Failure Other Serious 32 Female 4/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Inappropriate Antidiuretic Hormone Secretion Other Serious 74 Female 4/23/2008 Japan
Primary
Secondary
Inappropriate Antidiuretic Hormone Secretion Other Serious 74 Female 4/30/2008 Japan
Primary
Secondary
Thrombosis In Device Hospitalization 69 Male 4/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thrombosis In Device Hospitalization 69 Male 5/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Thrombosis Hospitalization 69 Male 5/29/2008 United Kingdom
Primary
Interacting
Drug Resistance Other Serious 69 Male 6/4/2008 United Kingdom
Primary
Concomitant
Interacting
Thrombosis Hospitalization 69 Male 6/6/2008 United Kingdom
Primary
Interacting
Thrombosis Hospitalization 6/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombosis In Device Life Threatening 69 Male 5/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis Hospitalization 69 Male 6/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 69 Male 6/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Thrombosis In Device Hospitalization 69 Male 6/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 69 Male 6/18/2008 United Kingdom
Primary
Concomitant
Interacting
Thrombosis In Device Hospitalization 69 Male 6/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 69 Male 6/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 69 Male 6/18/2008 United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 70 Male 6/25/2008
Primary
Concomitant
Thrombosis Hospitalization 69 Male 6/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis In Device Life Threatening 69 Male 6/24/2008 United Kingdom
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 69 Male 7/3/2008 United Kingdom
Primary
Concomitant
Interacting
Thrombosis In Device Hospitalization 69 Male 7/15/2008
Primary
Secondary
Thrombosis In Device Hospitalization 69 Male 7/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis In Device Life Threatening 69 Male 7/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Skin Exfoliation Hospitalization 5/1/2008 Male 9/2/2008 Other Health Professional France
Primary
Secondary
Thrombosis In Device Other Serious 69 Male 9/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 9/1/2008 75 Female 141 lb 11/10/2008 Consumer United States
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 9/1/2008 36 Male 12/11/2008 Physician France
Primary
Secondary
Concomitant
Weight Increased Other Serious 9 Female 12/23/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Vasculitis Other Serious 10/1/2007 43 Male 12/30/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 1/1/2005 80 Female 77 lb 1/5/2009
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 1/1/2005 80 Female 77 lb 1/5/2009
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/10/2008 1 Male 2/11/2009 Physician France
Primary
Concomitant
Tachycardia Hospitalization 10/10/2008 1 Male 2/12/2009 Physician France
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 10/10/2008 1 Male 2/20/2009 Physician France
Primary
Concomitant
Pneumonia Death 3/2/2009 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 10/10/2008 1 Male 3/6/2009 Physician France
Primary
Concomitant
Drug Ineffective Death 52 Male 4/8/2009 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 14 Male 110 lb 4/3/2009 Other Health Professional Mexico
Primary
Concomitant
Respiratory Gas Exchange Disorder Other Serious 52 Male 4/15/2009
Primary
Secondary
Concomitant
Vomiting Hospitalization 49 Male 5/11/2009 Other Health Professional Denmark
Primary
Secondary
Renal Failure Hospitalization 49 Male 5/14/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Failure Hospitalization 49 Male 5/18/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Vitamin D Decreased Other Serious 49 Male 5/18/2009
Primary
Secondary
Concomitant
Vomiting Hospitalization 49 Male 5/18/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2009 49 Male 6/12/2009 Other Health Professional Denmark
Primary
Secondary
Renal Tubular Necrosis Hospitalization 10/10/2008 1 Male 6/12/2009 Physician France
Primary
Concomitant
Optic Neuritis Disability 6/2/2009 77 Female 8/10/2009 Physician Denmark
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 44 Male 8/19/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 6/26/2009 Female 90 lb 8/21/2009 Japan
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 44 Male 8/24/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Visual Impairment Other Serious 6/26/2009 Female 90 lb 8/26/2009 Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/2009 60 9/7/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 6/26/2009 Female 90 lb 9/11/2009 Japan
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 44 Male 9/29/2009
Primary
Secondary
Skin Lesion Other Serious 44 Male 10/21/2009 Consumer Spain
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/11/2007 55 Female 10/29/2009 United Kingdom
Primary
Secondary
Concomitant
Skin Lesion Other Serious 44 Male 11/5/2009 Consumer Spain
Primary
Secondary
Concomitant
Headache Hospitalization 12/26/2008 59 Female 160 lb 12/3/2009 United States
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/25/2008 70 Female 73 lb 3/24/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 4/10/2010 64 Female 4/20/2010 Physician Japan
Primary
Secondary
Renal Failure Chronic Other Serious 4/10/2010 64 Female 5/14/2010 Physician Japan
Primary
Secondary
Affect Lability Other Serious 4/8/2010 60 Female 126 lb 5/17/2010 Consumer United Kingdom
Primary
Concomitant
Renal Failure Chronic Other Serious 4/10/2010 64 Female 5/20/2010 Physician Japan
Primary
Secondary
Nocardiosis Hospitalization 7/1/2006 Female 5/21/2010 Japan
Primary
Concomitant
Affect Lability Other Serious 4/8/2010 60 Female 126 lb 5/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 2/1/2010 Female 5/25/2010 Physician Australia
Primary
Concomitant
Affect Lability Other Serious 4/8/2010 60 Female 5/21/2010 United Kingdom
Primary
Concomitant
Nocardiosis Hospitalization 7/1/2006 Female 5/25/2010 Japan
Primary
Concomitant
Affect Lability Other Serious 4/8/2010 60 Female 5/28/2010 United Kingdom
Primary
Concomitant
Nausea Other Serious 44 Male 157 lb 6/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious 44 Male 157 lb 6/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Superinfection Hospitalization 7/1/2006 70 Female 7/15/2010 Physician Japan
Primary
Concomitant
Paradoxical Drug Reaction Other Serious Male 7/28/2010 Physician Australia
Primary
Secondary
Paradoxical Drug Reaction Other Serious 66 Male 7/28/2010 Physician Australia
Primary
Secondary
Cholestasis Hospitalization 5/26/2009 37 Female 8/9/2010 Other Health Professional France
Primary
Secondary
Concomitant
Nocardiosis Other Serious 70 Female 8/26/2010 Other Health Professional Japan
Primary
Concomitant
Affect Lability Other Serious 4/8/2010 60 Female 126 lb 8/31/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 50 Female 9/24/2010 Physician Netherlands
Primary
Secondary
Weight Decreased Other Serious 1/1/2005 50 Female 10/13/2010 Physician Netherlands
Primary
Secondary
Visual Impairment Other Serious 2/1/2010 Female 10/14/2010 Physician Australia
Primary
Concomitant
Interacting
Uveitis Other Serious 1/12/2009 81 Female 121 lb 10/28/2010 Physician Japan
Primary
Concomitant
Interacting
Pneumothorax Hospitalization 44 Male 12/2/2010 Other Health Professional France
Primary
Secondary
Respiratory Distress Other Serious 44 Male 12/13/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 44 Male 12/15/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 44 Male 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 2/1/2007 57 Male 1/5/2011 Other Health Professional Belgium
Primary
Secondary
Concomitant
Cough Other Serious 11/1/2002 51 Female 1/18/2011 Physician United States
Primary
Secondary
Concomitant
Vision Blurred 60 Male 90 lb 1/18/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 79 Female 3/24/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6/1/2007 79 Female 3/28/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6/1/2007 79 Female 4/8/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Disability 10/1/2010 70 Male 168 lb 5/10/2011 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Disability 10/1/2010 70 Male 168 lb 5/20/2011 Physician Japan
Primary
Concomitant
Oedema Peripheral Disability 10/1/2010 70 Male 168 lb 6/15/2011 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Disability 10/1/2010 70 Male 168 lb 6/16/2011 Physician Japan
Primary
Concomitant
Drug Hypersensitivity Disability 5/24/2011 63 Female 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 40 Female 7/12/2011 Pharmacist Japan
Primary
Concomitant
Interacting
Drug Resistance Other Serious 7/1/2000 19 Female 7/22/2011 Other Health Professional Sweden
Primary
Concomitant
Hypoalbuminaemia Disability 5/12/2009 68 Male 168 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Other Serious 11/20/2010 74 Female 8/12/2011 Physician Japan
Primary
Concomitant
Pruritus Hospitalization 12/21/2009 74 Male 90 lb 8/16/2011 Other Health Professional Japan
Primary
Secondary
Malaise Hospitalization 12/21/2009 74 Male 90 lb 8/16/2011 Other Health Professional Japan
Primary
Secondary
Drug Eruption 11/20/2010 74 Female 8/16/2011 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Other Serious 70 Male 8/19/2011 Other Health Professional Canada
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 70 Male 8/29/2011 Other Health Professional Canada
Primary
Concomitant
Interacting
Thrombocytopenia Death 11/17/2009 64 Male 97 lb 8/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Lung Infiltration Other Serious 68 Male 86 lb 9/12/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Diarrhoea Other Serious 68 Male 90 lb 9/13/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Pulmonary Cavitation Other Serious 61 Male 93 lb 9/13/2011 Other Health Professional Japan
Primary
Concomitant
Interacting

Drug Data