Clarithromycin combined with Rifabutin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Other Serious 12 Male 1/23/2006 United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 12/8/2005 60 Female 2/6/2006 France
Primary
Secondary
Immune Reconstitution Syndrome Hospitalization 3/11/2003 Male 121 lb 2/8/2006 United States
Primary
Concomitant
Urethral Discharge Hospitalization 10/22/2003 22 Female 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 31 Male 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 12/8/2005 60 Female 3/23/2006 Other Health Professional France
Primary
Secondary
Vomiting Hospitalization 3/10/2000 Female 3/31/2006 Physician Japan
Primary
Secondary
Concomitant
Steatorrhoea Other Serious 15 Male 4/7/2006 Argentina
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 Female 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/19/2006 Female 126 lb 8/7/2006 Physician Germany
Primary
Concomitant
Splenomegaly Other Serious 33 Female 11/3/2006 France
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/19/2006 Female 126 lb 12/13/2006 Physician Germany
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 4/5/2004 Female 12/28/2006 France
Primary
Concomitant
Tuberculosis Gastrointestinal Hospitalization 8/2/2005 29 Female 2/1/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/23/2006 Female 2/1/2007 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 11/23/2006 Female 46 lb 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 1/1/2006 Male 154 lb 3/30/2007 Consumer United States
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 4/5/2004 Female 4/5/2007 France
Primary
Concomitant
No Therapeutic Response Hospitalization 1/1/2006 34 Male 108 lb 5/14/2007 Physician France
Primary
Concomitant
Failure To Thrive Hospitalization 8/1/2006 Male 108 lb 6/8/2007 Physician United States
Primary
Concomitant
Tachycardia Other Serious 10 Female 6/12/2007 Consumer Canada
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 9/19/2006 Male 7/5/2007 Physician Japan
Primary
Secondary
Concomitant
Somnolence Disability 40 Male 7/10/2007 Other Health Professional Australia
Primary
Concomitant
Visual Field Defect Other Serious 9/19/2006 Male 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 9/19/2006 41 Male 9/24/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 9/19/2006 41 Male 10/22/2007 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 48 Female 10/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 Female 12/19/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 Female 12/28/2007 Physician Japan
Primary
Secondary
Concomitant
No Therapeutic Response Hospitalization 1/1/2006 34 Male 108 lb 3/12/2008 Physician France
Primary
Concomitant
Iridocyclitis Other Serious 2/13/2008 38 Female 90 lb 3/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 Female 5/8/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/28/2008 Male 97 lb 7/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Hospitalization 6/4/2008 Male 7/24/2008 Other Health Professional France
Primary
Concomitant
Colitis Other Serious 7/9/2008 Male 8/21/2008 Physician Japan
Primary
Secondary
Concomitant
Uveitis Other Serious 79 Male 8/25/2008 Switzerland
Primary
Secondary
Concomitant
Colitis Disability 7/9/2008 Male 9/5/2008 Physician Japan
Primary
Secondary
Concomitant
Uveitis Other Serious 79 Male 9/10/2008 Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/21/2003 Male 9/12/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 9/19/2006 Male 9/15/2008 Physician Japan
Primary
Secondary
Concomitant
Colitis Disability 7/9/2008 Male 9/17/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Viral Infection Other Serious 10 Male 12/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/16/2008 59 Female 123 lb 12/16/2008 Physician Germany
Primary
Concomitant
Vomiting Life Threatening 11/16/2008 59 Female 123 lb 12/17/2008 Physician Germany
Primary
Concomitant
Visual Field Defect Other Serious 12/12/2006 Male 12/24/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 9 Female 12/23/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 10/16/2008 Male 158 lb 1/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Tubular Necrosis Other Serious 10/16/2008 Male 158 lb 1/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 10/16/2008 Male 159 lb 1/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 10/16/2008 Male 158 lb 1/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 48 Male 1/12/2009
Primary
Secondary
Renal Tubular Necrosis Other Serious 10/16/2008 Male 158 lb 1/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 10/16/2008 1/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Required Intervention Male 1/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 1/28/2009 2/20/2009 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 12/23/2008 2/20/2009 Japan
Primary
Concomitant
Pneumonia Death 3/2/2009 Physician Japan
Primary
Concomitant
Sputum Retention Death 11/2/2008 Male 3/4/2009 Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 1/21/2009 3/9/2009 Physician Japan
Primary
Concomitant
Uveitis Other Serious 79 Male 6/4/2009 Other Health Professional Switzerland
Primary
Secondary
Uveitis Other Serious 79 Male 7/1/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Liver Disorder Other Serious 4/9/2009 82 7/10/2009 Japan
Primary
Concomitant
Vomiting Hospitalization 3/10/2000 Female 7/20/2009 Japan
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 5/1/2009 32 Female 7/14/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/1995 51 Male 8/7/2009 Physician United States
Primary
Secondary
Hepatitis Fulminant Life Threatening 5/16/2009 36 Female 8/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/2009 60 9/7/2009 Japan
Primary
Concomitant
Uveitis Other Serious 73 Male 9/25/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Vitritis Other Serious 73 Male 9/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Uveitis Other Serious 73 Male 9/29/2009 United Kingdom
Primary
Secondary
Vomiting Hospitalization 8/16/2009 43 Female 9/24/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/12/2009 Male 132 lb 10/16/2009 Other Health Professional Spain
Primary
Concomitant
Viral Infection Other Serious 10 Male 12/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 10 Male 12/18/2009 Physician United States
Primary
Secondary
Concomitant
Hepatitis Fulminant Life Threatening 5/16/2009 36 Female 2/19/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 44 Male 7/8/2010
Primary
Secondary
Cholestasis Hospitalization 5/26/2009 37 Female 8/9/2010 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 5/24/2007 60 Male 139 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 6/24/2007 60 Male 139 lb 8/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Death 4/1/2009 58 Female 8/31/2010 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 50 Female 9/24/2010 Physician Netherlands
Primary
Secondary
Weight Decreased Other Serious 1/1/2005 50 Female 10/13/2010 Physician Netherlands
Primary
Secondary
Uveitis Other Serious 64 Female 77 lb 10/14/2010 Physician Japan
Primary
Secondary
Uveitis Other Serious 81 Female 121 lb 10/14/2010 Physician Japan
Primary
Secondary
Uveitis Other Serious 1/13/2009 81 Female 121 lb 10/21/2010 Physician Japan
Primary
Secondary
Concomitant
Uveitis Other Serious 64 Female 77 lb 10/22/2010 Physician Japan
Primary
Secondary
Concomitant
Uveitis Other Serious 1/12/2009 81 Female 121 lb 10/28/2010 Physician Japan
Primary
Concomitant
Interacting
Uveitis Other Serious 64 Female 77 lb 11/9/2010 Physician Japan
Primary
Secondary
Concomitant
Uveitis Other Serious 64 Female 77 lb 11/9/2010 Physician Japan
Primary
Concomitant
Interacting
Multi-organ Failure Death 2/8/2010 59 Female 12/10/2010 Physician Japan
Primary
Concomitant
Tremor Other Serious 10/26/2008 55 Female 12/15/2010 Pharmacist Japan
Primary
Concomitant
Thrombocytopenia Other Serious 35 Male 12/9/2010 Physician United States
Primary
Concomitant
Rash Other Serious 2/10/2009 32 Male 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 10/27/2008 55 Female 1/10/2011 Pharmacist Japan
Primary
Concomitant
Cytomegalovirus Chorioretinitis Other Serious 2/10/2009 32 Male 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred 60 Male 90 lb 1/18/2011 Physician Japan
Primary
Concomitant
Pneumonia Death 12/28/2009 80 Male 81 lb 1/18/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 10/23/2009 64 Male 99 lb 1/20/2011 Physician Japan
Primary
Concomitant
Platelet Disorder Other Serious 35 Male 1/24/2011 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 35 Male 1/26/2011
Primary
Secondary
Concomitant
Anaemia Other Serious 35 Male 2/1/2011 Other Health Professional United States
Primary
Secondary
Haematuria Other Serious 35 Male 2/3/2011 Other Health Professional United States
Primary
Secondary
Aspartate Aminotransferase Increased Other Serious 35 Male 2/3/2011 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Other Serious 35 Male 2/3/2011 Other Health Professional United States
Primary
Secondary
Alanine Aminotransferase Increased Other Serious 3/12/2010 2 Male 22 lb 3/9/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 35 Male 4/25/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Abscess Hospitalization 11/28/2010 40 Male 197 lb 5/19/2011 Physician Germany
Primary
Secondary
Concomitant
Cytomegalovirus Chorioretinitis Other Serious 2/10/2009 32 Male 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Convulsion Death 5/3/2008 66 Male 99 lb 5/31/2011 Physician Japan
Primary
Concomitant
Aids Encephalopathy Death 11/9/2009 58 Female 6/2/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Viraemia Death 11/9/2009 58 Female 6/7/2011 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Death 11/9/2009 58 Female 6/28/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Disorder Disability 6/1/2009 65 Female 7/21/2011 Physician Japan
Primary
Concomitant
Pigmentation Disorder Disability 6/1/2009 65 Female 7/25/2011 Physician Japan
Primary
Secondary
Drug Resistance Other Serious 7/1/2000 19 Female 7/22/2011 Other Health Professional Sweden
Primary
Concomitant
Microtia Congenital Anomaly Male 7/28/2011 Physician France
Primary
Secondary
Aorticopulmonary Septal Defect Other Serious Male 7/29/2011 Physician France
Primary
Secondary
Polydactyly Other Serious 3/1/2011 Male 8/1/2011 Other Health Professional France
Primary
Secondary
Kidney Malformation Other Serious 3/1/2011 Male 5 lb 8/1/2011 Other Health Professional France
Primary
Secondary
Death Death 3/17/2011 71 Male 99 lb 8/26/2011 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 2/26/2010 68 Female 324 lb 9/7/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 68 Male 90 lb 9/13/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Anaemia Other Serious 1/17/2011 71 Male 99 lb 9/16/2011 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 68 Male 90 lb 9/26/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Cholestasis Hospitalization 10/27/2009 73 Female 72 lb 10/4/2011 Physician Japan
Primary
Concomitant
Neurological Decompensation Other Serious 10/24/2011 Other Health Professional Netherlands
Primary
Concomitant
Drug Interaction Other Serious 73 Male 110 lb 10/25/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Cholestasis Hospitalization 10/27/2009 73 Female 72 lb 10/27/2011 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 10/26/2010 50 Male 12/7/2011 Physician France
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/1/2011 60 Female 12/28/2011 Physician Germany
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 11/16/2010 80 Male 12/29/2011 Other Health Professional France
Primary
Secondary
Pyrexia Hospitalization 11/16/2010 80 Male 12/29/2011 Physician France
Primary
Secondary
Drug Ineffective Other Serious 44 Male 1/30/2012 Other Health Professional France
Primary
Secondary
Aids Encephalopathy Other Serious 2/1/2010 46 Male 2/8/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Congenital Aortic Atresia Other Serious Male 2/10/2012 Physician France
Primary
Secondary
Hyponatraemia Other Serious 9/4/2009 78 Female 90 lb 3/21/2012 Physician Japan
Primary
Concomitant
Gastroenteritis Other Serious 7/21/2009 75 Male 106 lb 4/10/2012 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 9/4/2009 78 Female 90 lb 4/27/2012 Physician Japan
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Hospitalization 3/22/2012 61 Male 273 lb 5/11/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/22/2012 61 Male 273 lb 5/21/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 10/13/2011 73 Male 5/25/2012 Physician France
Primary
Secondary
Gastroenteritis Other Serious 7/21/2009 75 Male 106 lb 5/30/2012 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/13/2011 73 Male 6/1/2012 Other Health Professional France
Primary
Secondary
Liver Disorder Hospitalization 11/2/2010 63 Female 103 lb 6/8/2012 Physician Japan
Primary
Concomitant
Hypokalaemia Other Serious 9/4/2009 78 Female 90 lb 6/18/2012 Physician Japan
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Death 3/22/2012 61 Male 245 lb 7/18/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Uveitis Hospitalization 4/1/2012 72 Male 7/24/2012 Other Health Professional France
Primary
Secondary
Prurigo Hospitalization 4/1/2012 72 Male 7/25/2012 Physician France
Primary
Secondary
Concomitant
Diarrhoea Life Threatening 7/25/2012 34 Male 8/13/2012 Other Health Professional France
Primary
Secondary
Convulsion Other Serious 7/25/2012 8/14/2012 Other Health Professional France
Primary
Secondary

Drug Data