Clarithromycin combined with Paracetamol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transaminases Increased Other Serious 2 Female 1/20/2006 Germany
Primary
Secondary
Transaminases Increased Other Serious 2 Female 2/9/2006 Germany
Primary
Secondary
Intentional Drug Misuse Death 5/16/2005 49 Female 12/14/2005 Physician United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 1/1/2006 31 Female 110 lb 4/7/2006 Consumer France
Primary
Secondary
Concomitant
Tonsillitis Streptococcal Hospitalization 3/31/2005 37 Female 101 lb 9/1/2006 Physician Japan
Primary
Secondary
Delirium Other Serious 63 Female 9/14/2006 Spain
Primary
Concomitant
Gangrene Hospitalization 12/1/2005 Male 148 lb 1/17/2007 Belgium
Primary
Concomitant
Thrombocytopenia Other Serious 27 Female 1/18/2007
Primary
Secondary
Agranulocytosis Other Serious 57 Male 1/18/2007
Primary
Secondary
Agranulocytosis Other Serious 4 Female 1/18/2007
Primary
Secondary
Agranulocytosis Other Serious 4 Female 1/25/2007 Germany
Primary
Secondary
Agranulocytosis Other Serious 57 Male 1/25/2007 Germany
Primary
Secondary
Agranulocytosis Other Serious 57 Male 1/31/2007 Germany
Primary
Secondary
Agranulocytosis Other Serious 4 Female 1/31/2007 Germany
Primary
Secondary
Peripheral Ischaemia Hospitalization 12/25/2006 47 Female 2/22/2007 Other Health Professional France
Primary
Secondary
Concomitant
Osteopenia Hospitalization 8/4/2005 61 Male 3/1/2007 Physician Belgium
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/1/2007 Female 226 lb 5/11/2007 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 5/1/2007 Female 226 lb 5/18/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 4/13/2007 37 Female 5/21/2007 Netherlands
Primary
Concomitant
Peripheral Ischaemia Hospitalization 12/25/2006 47 Female 5/31/2007 Other Health Professional France
Primary
Secondary
Concomitant
Gangrene Hospitalization 12/1/2005 Male 148 lb 6/1/2007 Belgium
Primary
Concomitant
Pneumonia Hospitalization 1/1/2007 46 Female 101 lb 6/28/2007 Physician Japan
Primary
Concomitant
Testicular Pain Hospitalization 5/12/2007 Male 227 lb 6/29/2007 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 33 Male 7/10/2007
Primary
Secondary
Toxic Epidermal Necrolysis Death 33 Male 7/11/2007
Primary
Secondary
Rash Hospitalization 7/23/2007 Female 8/9/2007 Physician Japan
Primary
Concomitant
Jaundice Hospitalization Male 92 lb 8/24/2007 Pharmacist United Kingdom
Primary
Concomitant
Injection Site Necrosis Other Serious 8/30/2006 47 Female 8/31/2007 Physician Netherlands
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/9/2007 50 Female 238 lb 9/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Poor Quality Drug Administered Death 2 Male 22 lb 10/1/2007 Physician Philippines
Primary
Concomitant
Multi-organ Failure Death 2 Male 22 lb 10/3/2007 Physician Philippines
Primary
Concomitant
Thrombocytopenia Life Threatening 7/25/2007 Male 154 lb 10/3/2007 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/6/2007 Male 10/19/2007 Physician United Kingdom
Primary
Concomitant
Gangrene Hospitalization 12/1/2005 Male 148 lb 10/25/2007 Belgium
Primary
Concomitant
Tremor Other Serious 9/14/2007 75 Male 146 lb 11/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash Maculo-papular Life Threatening 39 Female 11/12/2007 Physician Germany
Primary
Secondary
Concomitant
Tremor Life Threatening 9/14/2007 75 Male 146 lb 11/15/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Tremor Life Threatening 9/14/2007 75 Male 11/16/2007 United Kingdom
Primary
Secondary
Concomitant
Acute Hepatic Failure Hospitalization 39 Female 12/10/2007
Primary
Secondary
Concomitant
Jaundice Hospitalization 10/22/2007 68 Male 2/1/2008 Physician Ukraine
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 2/9/2008 Female 117 lb 2/15/2008 Physician Germany
Primary
Secondary
Urinary Tract Infection Hospitalization 1/28/2008 78 Female 145 lb 3/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/22/2007 68 Male 4/7/2008 Physician Ukraine
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 32 Female 4/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 1/28/2008 78 Female 145 lb 4/14/2008 United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 3/8/2008 10 Male 4/17/2008 Poland
Primary
Concomitant
Septic Shock Other Serious 12/20/2007 55 Female 4/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/28/2008 Female 121 lb 8/12/2008 Poland
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Tachycardia Other Serious 8/1/2008 Male 8/14/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 2/29/2008 Female 21 lb 11/21/2008 Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 10/27/2008 76 Male 154 lb 11/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious Male 152 lb 12/30/2008 Pharmacist Switzerland
Primary
Concomitant
Lip Swelling Other Serious 1/21/2009 55 Male 2/13/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/22/2007 68 Male 2/17/2009 Physician United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/22/2007 68 Male 2/18/2009 Physician United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 2/2/2009 31 Female 2/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Life Threatening 2/2/2009 31 Female 2/19/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pulse Absent Other Serious 3/16/2009 Other Health Professional Australia
Primary
Secondary
Productive Cough Other Serious 1/6/2009 115 lb 3/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 3/24/2009 United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 12/1/2008 70 Male 4/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Aplastic Anaemia Hospitalization Male 4/10/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 4/10/2009 United Kingdom
Primary
Concomitant
Aplastic Anaemia Hospitalization Male 4/14/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Aplastic Anaemia Hospitalization 72 Male 4/14/2009 Spain
Primary
Secondary
Concomitant
Productive Cough Other Serious 1/6/2009 Female 117 lb 4/17/2009 United Kingdom
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 4/17/2009 United Kingdom
Primary
Concomitant
Stenotrophomonas Infection Hospitalization 1/1/2007 75 Male 4/28/2009 Consumer Spain
Primary
Secondary
Concomitant
Stenotrophomonas Infection Other Serious Male 5/1/2009 Consumer Spain
Primary
Secondary
Concomitant
Overdose Hospitalization 1/1/2009 45 Female 5/8/2009 Other Health Professional Australia
Primary
Secondary
Pneumonia Other Serious 10/20/2003 Male 203 lb 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Gout Other Serious 3/12/2009 72 Female 6/25/2009 Physician United Kingdom
Primary
Concomitant
Infection Other Serious 6/7/2009 Female 7/1/2009 Other Health Professional Switzerland
Primary
Concomitant
Gout Other Serious 3/12/2009 72 Female 7/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Gout Required Intervention 3/12/2009 72 Female 6/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 7/15/2009 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Other Serious Male 8/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Liver Injury Other Serious 1/2/2009 43 Female 9/30/2009 Physician Switzerland
Primary
Secondary
Concomitant
Liver Injury Other Serious 1/2/2009 43 Female 10/2/2009 Physician Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 12/8/2008 70 Male 10/23/2009 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 5/1/2009 97 Male 11/6/2009 Consumer Australia
Primary
Secondary
Concomitant
Interacting
Irritability Other Serious 11/2/2009 Male 11/13/2009 Physician Italy
Primary
Concomitant
Irritability Other Serious 11/2/2009 Male 12/2/2009 Physician Italy
Primary
Concomitant
Purpura Hospitalization 11/22/2009 Male 12/2/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Purpura Hospitalization 11/22/2009 Male 12/11/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 8/23/2008 87 Female 12/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Other Serious 8/23/2008 87 Female 1/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Death 10/27/2008 76 Male 154 lb 1/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 12/23/2008 78 Female 1/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Purpura Hospitalization 11/22/2009 Male 1/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Irritability Other Serious 11/2/2009 Male 2/1/2010 Physician Italy
Primary
Concomitant
Withdrawal Syndrome Other Serious 12/23/2009 63 Male 2/5/2010 Pharmacist United Kingdom
Primary
Concomitant
Trismus Other Serious 2/8/2010 32 Female 115 lb 2/19/2010 Physician Spain
Primary
Concomitant
Hepatic Failure Hospitalization 1/5/2010 67 Male 172 lb 3/11/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 1/5/2010 67 Male 172 lb 3/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Tachycardia Life Threatening 3/3/2010 45 Female 240 lb 3/26/2010 Consumer United Kingdom
Primary
Concomitant
Tongue Discolouration Life Threatening 18 Male 4/29/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Tongue Discolouration Life Threatening 18 Male 4/29/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tongue Discolouration Life Threatening 18 Male 5/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Discolouration Life Threatening 18 Male 5/10/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tongue Discolouration Life Threatening 18 Male 5/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Discolouration Life Threatening 18 Male 5/15/2010 United Kingdom
Primary
Secondary
Concomitant
Hyperthermia Other Serious 18 Female 5/27/2010
Primary
Secondary
Hyperthermia Hospitalization 18 Female 5/27/2010 Other Health Professional Denmark
Primary
Concomitant
Sepsis Life Threatening 11/7/2009 74 Male 7/6/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 6/8/2010 72 Female 7/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Convulsion Hospitalization 6/8/2010 72 Female 7/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Off Label Use Other Serious 1/1/2009 26 Male 7/30/2010 Physician Spain
Primary
Concomitant
Interacting
Subdural Haematoma Life Threatening 11/7/2009 74 Male 8/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Off Label Use Other Serious 1/1/2009 26 Male 8/10/2010 Physician Spain
Primary
Concomitant
Interacting
Hepatocellular Injury Other Serious 11/1/2009 71 Male 10/11/2010 Consumer France
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/16/2010 46 Male 10/27/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Terminal State Life Threatening 10/30/2009 74 Male 11/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 6/10/2010 57 Male 11/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Mononucleosis Syndrome Hospitalization 8/22/2010 39 Female 139 lb 11/15/2010 Physician Italy
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/21/2010 32 Male 11/16/2010 Other Health Professional France
Primary
Secondary
Suicide Attempt Other Serious 10/7/2010 26 Female 11/16/2010 Physician Germany
Primary
Secondary
Wheezing Hospitalization 8/18/2010 40 Male 159 lb 11/23/2010 Physician Ireland
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 12/1/2010 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 10/12/2010 12/29/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 11/1/2010 32 Male 12/29/2010 Consumer France
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 11/25/2010 32 Male 1/10/2011 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/21/2008 70 Female 157 lb 1/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemolytic Anaemia Other Serious 11/22/2010 32 Male 1/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 10/12/2010 1/17/2011 Physician United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 6/10/2010 57 Male 1/19/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Keratitis Hospitalization 3/26/2010 75 Female 1/24/2011 Other Health Professional France
Primary
Secondary
Concomitant
Joint Stiffness Other Serious 3/26/2010 75 Female 2/4/2011 Other Health Professional France
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 6/10/2010 57 Male 2/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Gout Other Serious 3/12/2009 72 Female 3/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Liver Injury Hospitalization 1 Male 22 lb 3/31/2011 Other Health Professional Italy
Primary
Concomitant
Urticaria Hospitalization 2/27/2011 32 Female 127 lb 4/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Delirium Disability 3/24/2011 85 Female 4/13/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Delirium Disability 3/24/2011 85 Female 4/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Delirium Hospitalization 3/24/2011 85 Female 4/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Delirium Hospitalization 3/24/2011 85 Female 4/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Delirium Disability 3/24/2011 85 Female 4/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Multi-organ Failure Death 17 Female 5/5/2011 Other Health Professional Netherlands
Primary
Secondary
Jaundice Hospitalization 11/25/2010 32 Male 5/5/2011 Other Health Professional France
Primary
Secondary
Concomitant
Confusional State Disability 3/23/2011 85 Female 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Delirium Hospitalization 3/23/2011 85 Female 6/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/22/2011 53 Female 6/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Mental Disorder Hospitalization 7/28/2011 68 Male 8/24/2011 Pharmacist United Kingdom
Primary
Concomitant
Respiratory Failure Life Threatening 5/1/2011 75 Female 8/24/2011 Consumer United Kingdom
Primary
Concomitant
Interacting
Hepatocellular Injury Hospitalization 7/6/2008 56 Male 11/8/2011 Other Health Professional France
Primary
Secondary
Concomitant
Leukopenia Hospitalization 3/20/2012 94 Male 4/17/2012 Pharmacist United Kingdom
Primary
Concomitant
Nystagmus Hospitalization 3/7/2012 2 Male 4/26/2012 Physician United Kingdom
Primary
Concomitant
Drug-induced Liver Injury Hospitalization 5/22/2012 78 Male 122 lb 6/7/2012 Physician Japan
Primary
Concomitant
Drug-induced Liver Injury Hospitalization 5/22/2012 78 Male 122 lb 6/14/2012 Pharmacist Japan
Primary
Concomitant

Drug Data